{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T01:34:20Z","timestamp":1778636060779,"version":"3.51.4"},"reference-count":34,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s529767","type":"journal-article","created":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T12:00:12Z","timestamp":1751976012000},"page":"5899-5909","source":"Crossref","is-referenced-by-count":2,"title":["Effects of Dexmedetomidine on Minimum Alveolar Concentration of Sevoflurane for Blunting Sympathetic Response to Pneumoperitoneum: A Randomized Trial"],"prefix":"10.2147","volume":"Volume 19","author":[{"given":"Yan","family":"Yuan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guanlin","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinsheng","family":"Guan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenye","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8632-7300","authenticated-orcid":true,"given":"Weitao","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0561-6475","authenticated-orcid":true,"given":"Junyu","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8701-6639","authenticated-orcid":true,"given":"Dongsheng","family":"Dai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8488-8876","authenticated-orcid":true,"given":"Yusheng","family":"Yao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1799","DOI":"10.1200\/JCO.23.01019","volume":"42","author":"Fichtinger","year":"2024","journal-title":"J Clin Oncol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1552","DOI":"10.1016\/j.surg.2021.11.035","volume":"171","author":"Hakkenbrak","year":"2022","journal-title":"Surgery"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.ijsu.2015.04.083","volume":"18","author":"Coccolini","year":"2015","journal-title":"Int J Surg"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1389","DOI":"10.1016\/s0735-1097(98)00406-9","volume":"32","author":"Joris","year":"1998","journal-title":"J Am Coll Cardiol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1111\/anae.12168","volume":"68","author":"Aranake","year":"2013","journal-title":"Anaesthesia"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1213\/ANE.0000000000005784","volume":"135","author":"Wu","year":"2022","journal-title":"Anesth Analg"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1046\/j.1365-2346.1999.00446.x","volume":"16","author":"Ura","year":"1999","journal-title":"Eur J Anaesthesiol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"2155","DOI":"10.2165\/00003495-200161150-00001","volume":"61","author":"Gentz","year":"2001","journal-title":"Drugs"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1804","DOI":"10.1111\/bcp.15869","volume":"90","author":"Jacob","year":"2024","journal-title":"Br J Clin Pharmacol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.clinph.2022.08.019","volume":"143","author":"Miao","year":"2022","journal-title":"Clin Neurophysiol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1097\/00000542-200402000-00012","volume":"100","author":"Albertin","year":"2004","journal-title":"Anesthesiology"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1111\/jcpt.13263","volume":"46","author":"Chen","year":"2021","journal-title":"J Clin Pharm Ther"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1186\/s12871-020-01160-1","volume":"20","author":"Guo","year":"2020","journal-title":"BMC Anesthesiol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1007\/s40262-017-0507-7","volume":"56","author":"Weerink","year":"2017","journal-title":"Clin Pharmacokinet"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1097\/EJA.0b013e32833e266d","volume":"28","author":"Mantz","year":"2011","journal-title":"Eur J Anaesthesiol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1016\/s0952-8180(99)00081-1","volume":"11","author":"Fragen","year":"1999","journal-title":"J Clin Anesth"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1097\/00000542-199705000-00008","volume":"86","author":"Aantaa","year":"1997","journal-title":"Anesthesiology"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.jclinane.2013.12.012","volume":"26","author":"Yao","year":"2014","journal-title":"J Clin Anesth"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1610","DOI":"10.1001\/jama.2019.3087","volume":"321","author":"Juszczak","year":"2019","journal-title":"JAMA"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1097\/ALN.0000000000004381","volume":"138","author":"Joshi","year":"2023","journal-title":"Anesthesiology"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1097\/00000542-199305000-00002","volume":"78","author":"Dyck","year":"1993","journal-title":"Anesthesiology"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1093\/bja\/aeu400","volume":"114","author":"Zou","year":"2015","journal-title":"Br J Anaesth"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1097\/00000542-196305000-00016","volume":"24","author":"Merkel","year":"1963","journal-title":"Anesthesiology"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1097\/ALN.0000000000004282","volume":"137","author":"Oron","year":"2022","journal-title":"Anesthesiology"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1097\/EJA.0000000000001295","volume":"38","author":"M\u00fcller","year":"2021","journal-title":"Eur J Anaesthesiol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1016\/j.jclinane.2015.03.026","volume":"27","author":"Chen","year":"2015","journal-title":"J Clin Anesth"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1016\/j.jclinane.2010.02.006","volume":"22","author":"Luo","year":"2010","journal-title":"J Clin Anesth"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1111\/anae.14657","volume":"74","author":"Grape","year":"2019","journal-title":"Anaesthesia"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1016\/j.bja.2024.06.007","volume":"133","author":"Verret","year":"2024","journal-title":"Br J Anaesth"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1213\/ANE.0000000000005945","volume":"136","author":"Karam","year":"2023","journal-title":"Anesth Analg"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.bja.2023.04.024","volume":"131","author":"Cao","year":"2023","journal-title":"Br J Anaesth"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1097\/ALN.0000000000003725","volume":"134","author":"Beloeil","year":"2021","journal-title":"Anesthesiology"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"110287","DOI":"10.1016\/j.jclinane.2021.110287","volume":"72","author":"De Cassai","year":"2021","journal-title":"J Clin Anesth"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"245","DOI":"10.4097\/kja.21359","volume":"75","author":"De Cassai","year":"2022","journal-title":"Korean J Anesthesiol"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/104627","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/104627","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T12:00:14Z","timestamp":1751976014000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/effects-of-dexmedetomidine-on-minimum-alveolar-concentration-of-sevofl-peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":34,"URL":"https:\/\/doi.org\/10.2147\/dddt.s529767","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7]]}}}