{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T17:57:18Z","timestamp":1770746238950,"version":"3.49.0"},"reference-count":40,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s542160","type":"journal-article","created":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T09:55:14Z","timestamp":1759398914000},"page":"8935-8947","source":"Crossref","is-referenced-by-count":1,"title":["Dexmedetomidine\u2019s Effect on Catecholamine and Inflammation in Reducing In-Hospital Adverse Events for Older Patients with STEMI Undergoing Primary PCI"],"prefix":"10.2147","volume":"Volume 19","author":[{"given":"Guang-An","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanglong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linxiao","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruoxi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1093\/eurheartj\/ehad486","volume":"45","author":"Matter","year":"2024","journal-title":"Eur Heart J"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1177\/2047487318761091","volume":"25","author":"Seferovi\u0107","year":"2018","journal-title":"Eur J Prev Cardiol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1016\/j.jpsychires.2010.03.004","volume":"44","author":"von K\u00e4nel","year":"2010","journal-title":"J Psychiatr Res"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"300060520938959","DOI":"10.1177\/0300060520938959","volume":"48","author":"Wu","year":"2020","journal-title":"J Int Med Res"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1080\/13548500500448478","volume":"12","author":"Lemon","year":"2007","journal-title":"Psychol Health Med"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1016\/S1474-4422(24)00369-7","volume":"23","author":"Feigin","year":"2024","journal-title":"Lancet Neurol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1186\/s12877-024-04726-7","volume":"24","author":"Fu","year":"2024","journal-title":"BMC Geriatr"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1016\/j.bja.2019.07.027","volume":"123","author":"Wang","year":"2019","journal-title":"Br J Anaesth"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.jclinane.2017.06.004","volume":"41","author":"Lu","year":"2017","journal-title":"J Clin Anesth"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1113.e7","DOI":"10.1016\/j.jcrc.2013.07.062","volume":"28","author":"Goodwin","year":"2013","journal-title":"J Crit Care"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"176090","DOI":"10.1016\/j.ejphar.2023.176090","volume":"959","author":"Hou","year":"2023","journal-title":"Eur J Pharmacol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1007\/s00540-023-03261-w","volume":"37","author":"Takahashi","year":"2023","journal-title":"J Anesth"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"e2318611","DOI":"10.1001\/jamanetworkopen.2023.18611","volume":"6","author":"Yu","year":"2023","journal-title":"JAMA Netw Open"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1007\/s10554-020-02068-0","volume":"37","author":"Tang","year":"2021","journal-title":"Int J Cardiovasc Imag"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1136\/bmj.330.7497.960","volume":"330","author":"Mamdani","year":"2005","journal-title":"BMJ"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1097\/DCC.0000000000000346","volume":"38","author":"Rasheed","year":"2019","journal-title":"Dimens Crit Care Nurs"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1097\/00000539-199603000-00002","volume":"82","author":"Moerman","year":"1996","journal-title":"Anesth Analg"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1630","DOI":"10.1001\/jamainternmed.2014.3904","volume":"174","author":"Bradley","year":"2014","journal-title":"JAMA Intern Med"},{"key":"ref19","first-page":"61","volume":"48","author":"Westermann","year":"2002","journal-title":"Clin Lab"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"79","DOI":"10.2176\/nmc.oa.2017-0188","volume":"58","author":"Nii","year":"2018","journal-title":"Neurol Med Chir"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1007\/s00540-012-1460-0","volume":"27","author":"Mavridou","year":"2013","journal-title":"J Anesth"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1097\/ALN.0000000000000951","volume":"124","author":"Djaiani","year":"2016","journal-title":"Anesthesiology"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1097\/TA.0000000000001069","volume":"81","author":"Pajoumand","year":"2016","journal-title":"J Trauma Acute Care Surg"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"e01317","DOI":"10.1002\/brb3.1317","volume":"9","author":"Ren","year":"2019","journal-title":"Brain Behav"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1007\/s00540-009-0777-9","volume":"23","author":"Nakano","year":"2009","journal-title":"J Anesth"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1177\/1538574410363621","volume":"44","author":"Huncke","year":"2010","journal-title":"Vasc Endovasc Surg"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1097\/00000539-200003000-00035","volume":"90","author":"Hall","year":"2000","journal-title":"Anesth Analg"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1097\/00000542-200008000-00016","volume":"93","author":"Ebert","year":"2000","journal-title":"Anesthesiology"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1768","DOI":"10.1093\/europace\/euaa232","volume":"22","author":"Kowlgi","year":"2020","journal-title":"Europace"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1253\/circj.CJ-23-0023","volume":"88","author":"Hanada","year":"2024","journal-title":"Circ J"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1161\/01.CIR.101.9.969","volume":"101","author":"Rathore","year":"2000","journal-title":"Circulation"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1378\/chest.15-0358","volume":"148","author":"Walkey","year":"2015","journal-title":"Chest"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"5158362","DOI":"10.1155\/2022\/5158362","volume":"2022","author":"Zhong","year":"2022","journal-title":"Cardiol Res Pract"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1016\/j.athoracsur.2011.04.099","volume":"92","author":"Chrysostomou","year":"2011","journal-title":"Ann Thorac Surg"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.genhosppsych.2015.11.004","volume":"39","author":"Meister","year":"2016","journal-title":"Gen Hosp Psychiatry"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1080\/1354750X.2017.1279218","volume":"22","author":"Milwidsky","year":"2017","journal-title":"Biomarkers"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1002\/jts.20445","volume":"22","author":"Helfricht","year":"2009","journal-title":"J Trauma Stress"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1955","DOI":"10.1161\/01.CIR.0000125690.80303.A8","volume":"109","author":"Ridker","year":"2004","journal-title":"Circulation"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1007\/s12160-015-9744-x","volume":"50","author":"Ginzburg","year":"2016","journal-title":"Ann Behav Med"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"1482","DOI":"10.1016\/j.socscimed.2011.03.016","volume":"72","author":"Heffner","year":"2011","journal-title":"Soc Sci Med"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/107539","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/107539","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T09:55:15Z","timestamp":1759398915000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/dexmedetomidines-effect-on-catecholamine-and-inflammation-in-reducing--peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":40,"URL":"https:\/\/doi.org\/10.2147\/dddt.s542160","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10]]}}}