{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:23:59Z","timestamp":1792614239935,"version":"4.5.0"},"reference-count":230,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s559919","type":"journal-article","created":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T11:50:13Z","timestamp":1763725813000},"page":"10383-10409","source":"Crossref","is-referenced-by-count":26,"title":["The Clinical Application of GLP-1RAs and GLP-1\/GIP Dual Receptor Agonists Based on Pharmacological Mechanisms: A Review"],"prefix":"10.2147","volume":"Volume 19","author":[{"given":"Zhao","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanshan","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyan","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luguang","family":"Sheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mai Re","family":"YanMu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1016\/j.cmet.2018.03.001","volume":"27","author":"Drucker","year":"2018","journal-title":"Cell Metab"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"21","DOI":"10.2337\/db18-0729","volume":"68","author":"Holt","year":"2019","journal-title":"Diabetes"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.molmet.2019.09.010","volume":"30","author":"M\u00fcller","year":"2019","journal-title":"Mol Metab"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/s11154-014-9289-5","volume":"15","author":"Shah","year":"2014","journal-title":"Rev Endocr Metab Disord"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"4186","DOI":"10.2337\/db14-0849","volume":"63","author":"Van Bloemendaal","year":"2014","journal-title":"Diabetes"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1925","DOI":"10.1007\/s00125-022-05787-2","volume":"65","author":"Davies","year":"2022","journal-title":"Diabetologia"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"American Diabetes Association Professional Practice Committee. 9. Pharmacologic approaches to glycemic treatment: standards of medical care in diabetes-2022. Diabetes Care. 2022;45(Suppl 1):S125\u2013s43. doi:10.2337\/dc22-S009","DOI":"10.2337\/dc22-S009"},{"key":"ref8","first-page":"1405","volume":"17","author":"Scheen","year":"2021","journal-title":"Rev Med Suisse"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"765","DOI":"10.2337\/dc20-1473","volume":"44","author":"Frias","year":"2021","journal-title":"Diabetes Care"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1016\/S2213-8587(21)00174-1","volume":"9","author":"Fr\u00edas","year":"2021","journal-title":"Lancet Diabetes Endocrinol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.cmet.2016.06.021","volume":"24","author":"Tsch\u00f6p","year":"2016","journal-title":"Cell Metab"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1038\/nrendo.2015.3","volume":"11","author":"Scheen","year":"2015","journal-title":"Nat Rev Endocrinol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"101090","DOI":"10.1016\/j.molmet.2020.101090","volume":"46","author":"Baggio","year":"2021","journal-title":"Mol Metab"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1007\/s12020-020-02223-6","volume":"68","author":"Cao","year":"2020","journal-title":"Endocrine"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"178","DOI":"10.3389\/fendo.2020.00178","volume":"11","author":"Gilbert","year":"2020","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"465","DOI":"10.2215\/CJN.11881019","volume":"15","author":"Mann","year":"2020","journal-title":"Clin J Am Soc Nephrol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"107520","DOI":"10.1016\/j.jdiacomp.2019.107520","volume":"34","author":"Anderson","year":"2020","journal-title":"J Diabetes Complications"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1007\/s13300-020-00786-1","volume":"11","author":"Thangavelu","year":"2020","journal-title":"Diabetes Ther"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.53738\/REVMED.2022.18.792.1539","volume":"18","author":"Scheen","year":"2022","journal-title":"Rev Med Suisse"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1038\/s42255-020-00327-x","volume":"3","author":"Gribble","year":"2021","journal-title":"Nat Metab"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1186\/1756-0500-7-849","volume":"7","author":"Lastya","year":"2014","journal-title":"BMC Res Notes"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1136\/gut.38.6.916","volume":"38","author":"Ranganath","year":"1996","journal-title":"Gut"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1016\/j.cmet.2013.04.008","volume":"17","author":"Campbell","year":"2013","journal-title":"Cell Metab"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"1696","DOI":"10.1016\/S0140-6736(06)69705-5","volume":"368","author":"Drucker","year":"2006","journal-title":"Lancet"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"672","DOI":"10.3389\/fendo.2018.00672","volume":"9","author":"Rowlands","year":"2018","journal-title":"Front Endocrinol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"R470","DOI":"10.1152\/ajpregu.00732.2002","volume":"285","author":"Vrang","year":"2003","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1038\/s42255-021-00344-4","volume":"3","author":"Brierley","year":"2021","journal-title":"Nat Metab"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.134359","volume":"5","author":"Cheng","year":"2020","journal-title":"JCI Insight"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1210\/jc.2009-1062","volume":"95","author":"Beglinger","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/S0167-0115(02)00157-X","volume":"110","author":"Hansen","year":"2002","journal-title":"Regul Pept"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1186\/s12986-016-0153-3","volume":"13","author":"Bodnaruc","year":"2016","journal-title":"Nutr Metab (Lond)"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"3103","DOI":"10.1210\/en.2011-0174","volume":"152","author":"Kanoski","year":"2011","journal-title":"Endocrinology"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"584","DOI":"10.3389\/fendo.2018.00584","volume":"9","author":"Paternoster","year":"2018","journal-title":"Front Endocrinol"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1172\/JCI81335","volume":"127","author":"Gaykema","year":"2017","journal-title":"J Clin Invest"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"1350","DOI":"10.1016\/j.molmet.2017.08.009","volume":"6","author":"Shi","year":"2017","journal-title":"Mol Metab"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.133429","volume":"5","author":"Gabery","year":"2020","journal-title":"JCI Insight"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1016\/j.coph.2009.09.003","volume":"9","author":"Burcelin","year":"2009","journal-title":"Curr Opin Pharmacol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"4356","DOI":"10.1210\/en.2014-1248","volume":"155","author":"Richard","year":"2014","journal-title":"Endocrinology"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1172\/JCI25483","volume":"117","author":"Hansotia","year":"2007","journal-title":"J Clin Invest"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"3127","DOI":"10.1210\/endo.139.7.6092","volume":"139","author":"Scrocchi","year":"1998","journal-title":"Endocrinology"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1038\/nm1196-1254","volume":"2","author":"Scrocchi","year":"1996","journal-title":"Nat Med"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"4678","DOI":"10.1210\/en.2010-0289","volume":"151","author":"Ayala","year":"2010","journal-title":"Endocrinology"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"4768","DOI":"10.1210\/en.2008-0180","volume":"149","author":"Knauf","year":"2008","journal-title":"Endocrinology"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"2046","DOI":"10.2337\/db07-1824","volume":"57","author":"Sandoval","year":"2008","journal-title":"Diabetes"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.1210\/en.2008-1221","volume":"150","author":"R\u00fcttimann","year":"2009","journal-title":"Endocrinology"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"1680","DOI":"10.1210\/en.2008-1045","volume":"150","author":"Williams","year":"2009","journal-title":"Endocrinology"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1111\/dom.13162","volume":"20","author":"Aroda","year":"2018","journal-title":"Diabetes Obes Metab"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"e2710","DOI":"10.1210\/clinem\/dgaa327","volume":"105","author":"Holst","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"E418","DOI":"10.1210\/jc.2013-3644","volume":"99","author":"Christensen","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/dom.14831","volume":"25","author":"De Block","year":"2023","journal-title":"Diabetes Obes Metab"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"2468","DOI":"10.2337\/dbi21-0026","volume":"70","author":"Holst","year":"2021","journal-title":"Diabetes"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"1076","DOI":"10.1210\/jcem-24-10-1076","volume":"24","author":"Elrick","year":"1964","journal-title":"J Clin Endocrinol Metab"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"6820377","DOI":"10.1155\/2022\/6820377","volume":"2022","author":"Xu","year":"2022","journal-title":"Cardiovasc Ther"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1038\/nrendo.2012.140","volume":"8","author":"Meier","year":"2012","journal-title":"Nat Rev Endocrinol"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1111\/dom.14496","volume":"23 Suppl 3","author":"Nauck","year":"2021","journal-title":"Diabetes Obes Metab"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1111\/jdi.12466","volume":"7 Suppl 1","author":"D\u2019alessio","year":"2016","journal-title":"J Diabetes Investig"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1038\/s41569-023-00849-3","volume":"20","author":"Ussher","year":"2023","journal-title":"Nat Rev Cardiol"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"721135","DOI":"10.3389\/fendo.2021.721135","volume":"12","author":"Zhao","year":"2021","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"2221","DOI":"10.1056\/NEJMoa2307563","volume":"389","author":"Lincoff","year":"2023","journal-title":"N Engl J Med"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1007\/s42000-023-00488-w","volume":"22","author":"Liakos","year":"2023","journal-title":"Hormones"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.molmet.2018.09.009","volume":"18","author":"Coskun","year":"2018","journal-title":"Mol Metab"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1210\/endrev\/bnaa032","volume":"42","author":"Mclean","year":"2021","journal-title":"Endocr Rev"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"3103","DOI":"10.2337\/db11-0979","volume":"60","author":"Christensen","year":"2011","journal-title":"Diabetes"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"2504","DOI":"10.1111\/dom.14166","volume":"22","author":"Horowitz","year":"2020","journal-title":"Diabetes Obes Metab"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1016\/j.diabet.2017.05.009","volume":"43","author":"Nakatani","year":"2017","journal-title":"Diabetes Metab"},{"key":"ref66","doi-asserted-by":"publisher","first-page":"407","DOI":"10.2337\/db13-1764","volume":"63","author":"Tong","year":"2014","journal-title":"Diabetes"},{"key":"ref67","doi-asserted-by":"publisher","first-page":"4749","DOI":"10.1113\/jphysiol.2009.175067","volume":"587","author":"Holmes","year":"2009","journal-title":"J Physiol"},{"key":"ref68","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/0165-1838(83)90134-0","volume":"9","author":"Schwartz","year":"1983","journal-title":"J Auton Nerv Syst"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1369\/0022155413497586","volume":"61","author":"Broide","year":"2013","journal-title":"J Histochem Cytochem"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1210\/jc.2017-02006","volume":"103","author":"Halim","year":"2018","journal-title":"J Clin Endocrinol Metab"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/5584_2020_496","volume":"1307","author":"Maselli","year":"2021","journal-title":"Adv Exp Med Biol"},{"key":"ref72","doi-asserted-by":"publisher","first-page":"912","DOI":"10.1210\/jcem.76.4.8473405","volume":"76","author":"Nauck","year":"1993","journal-title":"J Clin Endocrinol Metab"},{"key":"ref73","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1097\/ALN.0000000000004752","volume":"140","author":"Weber","year":"2024","journal-title":"Anesthesiology"},{"key":"ref74","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1111\/anae.16306","volume":"79","author":"Milder","year":"2024","journal-title":"Anaesthesia"},{"key":"ref75","doi-asserted-by":"publisher","first-page":"14","DOI":"10.5694\/mja2.52170","volume":"220","author":"Raven","year":"2024","journal-title":"Med J Aust"},{"key":"ref76","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1056\/NEJMoa2032183","volume":"384","author":"Wilding","year":"2021","journal-title":"N Engl J Med"},{"key":"ref77","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1056\/NEJMoa2206038","volume":"387","author":"Jastreboff","year":"2022","journal-title":"N Engl J Med"},{"key":"ref78","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1111\/dom.12824","volume":"19","author":"Bettge","year":"2017","journal-title":"Diabetes Obes Metab"},{"key":"ref79","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1001\/jamainternmed.2013.2720","volume":"173","author":"Singh","year":"2013","journal-title":"JAMA Intern Med"},{"key":"ref80","doi-asserted-by":"publisher","first-page":"107","DOI":"10.4158\/CS-2019-0472","volume":"26","author":"Garber","year":"2020","journal-title":"Endocr Pract"},{"key":"ref81","doi-asserted-by":"publisher","first-page":"2131","DOI":"10.1053\/j.gastro.2007.03.054","volume":"132","author":"Baggio","year":"2007","journal-title":"Gastroenterology"},{"key":"ref82","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1111\/dom.12251","volume":"16","author":"Seufert","year":"2014","journal-title":"Diabetes Obes Metab"},{"key":"ref83","doi-asserted-by":"publisher","first-page":"1158","DOI":"10.3390\/nu13041158","volume":"13","author":"Cifuentes","year":"2021","journal-title":"Nutrients"},{"key":"ref84","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.1002\/phar.1507","volume":"34","author":"Trujillo","year":"2014","journal-title":"Pharmacotherapy"},{"key":"ref85","doi-asserted-by":"publisher","first-page":"1470","DOI":"10.1007\/s12325-021-01637-6","volume":"38","author":"Jiang","year":"2021","journal-title":"Adv Ther"},{"key":"ref86","doi-asserted-by":"publisher","first-page":"108904","DOI":"10.1016\/j.diabres.2021.108904","volume":"177","author":"Xia","year":"2021","journal-title":"Diabetes Res Clin Pract"},{"key":"ref87","doi-asserted-by":"publisher","first-page":"e061807","DOI":"10.1136\/bmjopen-2022-061807","volume":"13","author":"Ma","year":"2023","journal-title":"BMJ Open"},{"key":"ref88","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1001\/jama.2022.0078","volume":"327","author":"Dahl","year":"2022","journal-title":"JAMA"},{"key":"ref89","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1016\/S2213-8587(22)00188-7","volume":"10","author":"Inagaki","year":"2022","journal-title":"Lancet Diabetes Endocrinol"},{"key":"ref90","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1016\/S2213-8587(22)00187-5","volume":"10","author":"Kadowaki","year":"2022","journal-title":"Lancet Diabetes Endocrinol"},{"key":"ref91","doi-asserted-by":"publisher","first-page":"e076410","DOI":"10.1136\/bmj-2023-076410","volume":"384","author":"Yao","year":"2024","journal-title":"BMJ"},{"key":"ref92","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1172\/JCI990","volume":"101","author":"Flint","year":"1998","journal-title":"J Clin Invest"},{"key":"ref93","doi-asserted-by":"publisher","first-page":"1300","DOI":"10.1016\/S0140-6736(87)91194-9","volume":"2","author":"Kreymann","year":"1987","journal-title":"Lancet"},{"key":"ref94","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1016\/S0140-6736(23)01233-3","volume":"402","author":"Sherrill","year":"2023","journal-title":"Lancet"},{"key":"ref95","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1111\/dom.14054","volume":"22","author":"Thethi","year":"2020","journal-title":"Diabetes Obes Metab"},{"key":"ref96","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/S0140-6736(23)01185-6","volume":"402","author":"Knop","year":"2023","journal-title":"Lancet"},{"key":"ref97","doi-asserted-by":"publisher","first-page":"29959","DOI":"10.1073\/pnas.2014879117","volume":"117","author":"Kawai","year":"2020","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref98","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1016\/S0140-6736(23)01302-8","volume":"402","author":"Frias","year":"2023","journal-title":"Lancet"},{"key":"ref99","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1056\/NEJMoa2302392","volume":"389","author":"Wharton","year":"2023","journal-title":"N Engl J Med"},{"key":"ref100","doi-asserted-by":"publisher","first-page":"8208","DOI":"10.1021\/acs.jmedchem.1c01856","volume":"65","author":"Griffith","year":"2022","journal-title":"J Med Chem"},{"key":"ref101","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1007\/s12098-023-04613-w","volume":"90","author":"Soni","year":"2023","journal-title":"Indian J Pediatr"},{"key":"ref102","doi-asserted-by":"publisher","first-page":"e2314493","DOI":"10.1001\/jamanetworkopen.2023.14493","volume":"6","author":"Saxena","year":"2023","journal-title":"JAMA Netw Open"},{"key":"ref103","doi-asserted-by":"publisher","first-page":"117202","DOI":"10.1016\/j.biopha.2024.117202","volume":"178","author":"Zhao","year":"2024","journal-title":"Biomed Pharmacother"},{"key":"ref104","doi-asserted-by":"publisher","first-page":"2613","DOI":"10.1016\/j.apsb.2024.03.011","volume":"14","author":"He","year":"2024","journal-title":"Acta Pharm Sin B"},{"key":"ref105","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1016\/S2213-8587(24)00155-4","volume":"12","author":"Apperloo","year":"2024","journal-title":"Lancet Diabetes Endocrinol"},{"key":"ref106","doi-asserted-by":"publisher","first-page":"1394","DOI":"10.1056\/NEJMoa2313917","volume":"390","author":"Kosiborod","year":"2024","journal-title":"N Engl J Med"},{"key":"ref107","doi-asserted-by":"publisher","first-page":"101470","DOI":"10.1016\/j.diabet.2023.101470","volume":"49","author":"Monney","year":"2023","journal-title":"Diabetes Metab"},{"key":"ref108","doi-asserted-by":"publisher","first-page":"139239","DOI":"10.1155\/2013\/139239","volume":"2013","author":"Makki","year":"2013","journal-title":"ISRN Inflamm"},{"key":"ref109","doi-asserted-by":"publisher","first-page":"338","DOI":"10.2174\/18715273113126660137","volume":"13","author":"Kamal","year":"2014","journal-title":"CNS Neurol Disord Drug Targets"},{"key":"ref110","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/S0197-4580(00)00124-X","volume":"21","author":"Akiyama","year":"2000","journal-title":"Neurobiol Aging"},{"key":"ref111","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1016\/j.neuint.2012.12.016","volume":"62","author":"Taylor","year":"2013","journal-title":"Neurochem Int"},{"key":"ref112","doi-asserted-by":"publisher","first-page":"1387","DOI":"10.1177\/1535370215576313","volume":"240","author":"Stojkovska","year":"2015","journal-title":"Exp Biol Med (Maywood)"},{"key":"ref113","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1007\/s00401-003-0766-2","volume":"106","author":"Imamura","year":"2003","journal-title":"Acta Neuropathol"},{"key":"ref114","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.neuropharm.2017.12.001","volume":"136","author":"Ferrario","year":"2018","journal-title":"Neuropharmacology"},{"key":"ref115","doi-asserted-by":"publisher","DOI":"10.3390\/cells10051236","volume":"10","author":"Burillo","year":"2021","journal-title":"Cells"},{"key":"ref116","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1007\/s00592-013-0546-y","volume":"51","author":"Heni","year":"2014","journal-title":"Acta Diabetol"},{"key":"ref117","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1096\/fj.06-7703com","volume":"22","author":"Zhao","year":"2008","journal-title":"FASEB J"},{"key":"ref118","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.bbr.2017.11.015","volume":"339","author":"Zhang","year":"2018","journal-title":"Behav Brain Res"},{"key":"ref119","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1016\/j.cmet.2022.04.001","volume":"34","author":"Mayneris-Perxachs","year":"2022","journal-title":"Cell Metab"},{"key":"ref120","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/1471-2202-13-33","volume":"13","author":"Hunter","year":"2012","journal-title":"BMC Neurosci"},{"key":"ref121","doi-asserted-by":"publisher","first-page":"637","DOI":"10.3233\/JAD-130491","volume":"37","author":"Yang","year":"2013","journal-title":"J Alzheimers Dis"},{"key":"ref122","doi-asserted-by":"publisher","first-page":"623","DOI":"10.3233\/JAD-130584","volume":"37","author":"Xiong","year":"2013","journal-title":"J Alzheimers Dis"},{"key":"ref123","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1111\/jnc.13248","volume":"135","author":"Ma","year":"2015","journal-title":"J Neurochem"},{"key":"ref124","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1177\/13872877251329439","volume":"105","author":"Zhai","year":"2025","journal-title":"J Alzheimers Dis"},{"key":"ref125","doi-asserted-by":"publisher","first-page":"171271","DOI":"10.1016\/j.peptides.2024.171271","volume":"179","author":"Yang","year":"2024","journal-title":"Peptides"},{"key":"ref126","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1186\/s12967-024-04927-z","volume":"22","author":"Fontanella","year":"2024","journal-title":"J Transl Med"},{"key":"ref127","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/j.bbr.2018.08.006","volume":"356","author":"Watson","year":"2019","journal-title":"Behav Brain Res"},{"key":"ref128","doi-asserted-by":"publisher","first-page":"285","DOI":"10.3390\/cimb47040285","volume":"47","author":"Al Qassab","year":"2025","journal-title":"Curr Issues Mol Biol"},{"key":"ref129","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1007\/s11154-023-09807-3","volume":"24","author":"Garc\u00eda-Casares","year":"2023","journal-title":"Rev Endocr Metabol Disord"},{"key":"ref130","doi-asserted-by":"publisher","first-page":"3812","DOI":"10.3390\/ijms25073812","volume":"25","author":"Kalinderi","year":"2024","journal-title":"Int J Mol Sci"},{"key":"ref131","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1001\/jama.2024.1017","volume":"331","author":"Rubin","year":"2024","journal-title":"JAMA"},{"key":"ref132","doi-asserted-by":"publisher","first-page":"1873","DOI":"10.2337\/dci24-0003","volume":"47","author":"Drucker","year":"2024","journal-title":"Diabetes Care"},{"key":"ref133","doi-asserted-by":"publisher","first-page":"1176","DOI":"10.1056\/NEJMoa2312323","volume":"390","author":"Meissner","year":"2024","journal-title":"N Engl J Med"},{"key":"ref134","doi-asserted-by":"publisher","first-page":"1421","DOI":"10.1016\/j.parkreldis.2015.10.006","volume":"21","author":"Horv\u00e1th","year":"2015","journal-title":"Parkinsonism Relat Disord"},{"key":"ref135","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.159863","volume":"7","author":"Klausen","year":"2022","journal-title":"JCI Insight"},{"key":"ref136","doi-asserted-by":"publisher","first-page":"819470","DOI":"10.3389\/fphar.2022.819470","volume":"13","author":"Zhu","year":"2022","journal-title":"Front Pharmacol"},{"key":"ref137","doi-asserted-by":"publisher","first-page":"2","DOI":"10.3390\/receptors4010002","volume":"4","author":"Teixeira","year":"2025","journal-title":"Receptors"},{"key":"ref138","doi-asserted-by":"publisher","first-page":"103385","DOI":"10.1016\/j.eclinm.2025.103385","volume":"86","author":"Wang","year":"2025","journal-title":"eClinicalMedicine"},{"key":"ref139","volume":"16","author":"Sun","year":"2025","journal-title":"Frontiers in Immunology"},{"key":"ref140","doi-asserted-by":"publisher","first-page":"Cd014885","DOI":"10.1002\/14651858.CD014885.pub2","volume":"6","author":"Mohanannair Geethadevi","year":"2023","journal-title":"Cochrane Database Syst Rev"},{"key":"ref141","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1111\/bph.15677","volume":"179","author":"Klausen","year":"2022","journal-title":"Br J Pharmacol"},{"key":"ref142","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1016\/S0140-6736(19)31775-1","volume":"394","author":"Carvalho","year":"2019","journal-title":"Lancet"},{"key":"ref143","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1017\/S0033291716002841","volume":"47","author":"Borges","year":"2017","journal-title":"Psychol Med"},{"key":"ref144","doi-asserted-by":"publisher","first-page":"Cd013308","DOI":"10.1002\/14651858.CD013308.pub2","volume":"6","author":"Theodoulou","year":"2023","journal-title":"Cochrane Database Syst Rev"},{"key":"ref145","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.1111\/add.14234","volume":"113","author":"Peacock","year":"2018","journal-title":"Addiction"},{"key":"ref146","doi-asserted-by":"publisher","first-page":"2627","DOI":"10.1007\/s00204-021-03068-2","volume":"95","author":"Baldo","year":"2021","journal-title":"Arch Toxicol"},{"key":"ref147","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1038\/nrn3104","volume":"12","author":"Badiani","year":"2011","journal-title":"Nat Rev Neurosci"},{"key":"ref148","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1037\/amp0000059","volume":"71","author":"Berridge","year":"2016","journal-title":"Am Psychol"},{"key":"ref149","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1176\/appi.ajp.2019.19121284","volume":"177","author":"Volkow","year":"2020","journal-title":"Am J Psychiatry"},{"key":"ref150","doi-asserted-by":"publisher","first-page":"136","DOI":"10.3389\/fnbeh.2019.00136","volume":"13","author":"Zorrilla","year":"2019","journal-title":"Front Behav Neurosci"},{"key":"ref151","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1001\/jamapsychiatry.2018.3126","volume":"76","author":"Volkow","year":"2019","journal-title":"JAMA Psychiatry"},{"key":"ref152","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1038\/nrn.2017.130","volume":"18","author":"Volkow","year":"2017","journal-title":"Nat Rev Neurosci"},{"key":"ref153","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.drugalcdep.2018.06.038","volume":"191","author":"Lee","year":"2018","journal-title":"Drug Alcohol Depend"},{"key":"ref154","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1016\/j.celrep.2015.06.062","volume":"12","author":"Wang","year":"2015","journal-title":"Cell Rep"},{"key":"ref155","doi-asserted-by":"publisher","first-page":"1969","DOI":"10.1038\/npp.2015.47","volume":"40","author":"Harasta","year":"2015","journal-title":"Neuropsychopharmacology"},{"key":"ref156","doi-asserted-by":"publisher","first-page":"6985","DOI":"10.1523\/JNEUROSCI.0115-14.2014","volume":"34","author":"Mietlicki-Baase","year":"2014","journal-title":"J Neurosci"},{"key":"ref157","doi-asserted-by":"publisher","first-page":"e019562","DOI":"10.1136\/bmjopen-2017-019562","volume":"8","author":"Antonsen","year":"2018","journal-title":"BMJ Open"},{"key":"ref158","doi-asserted-by":"publisher","first-page":"e583","DOI":"10.1038\/tp.2015.68","volume":"5","author":"Suchankova","year":"2015","journal-title":"Transl Psychiatry"},{"key":"ref159","doi-asserted-by":"publisher","first-page":"1372","DOI":"10.1530\/EC-19-0317","volume":"8","author":"Lanng","year":"2019","journal-title":"Endocr Connect"},{"key":"ref160","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.physbeh.2019.03.026","volume":"206","author":"Hernandez","year":"2019","journal-title":"Physiol Behav"},{"key":"ref161","doi-asserted-by":"publisher","first-page":"e69010","DOI":"10.1371\/journal.pone.0069010","volume":"8","author":"Egecioglu","year":"2013","journal-title":"PLoS One"},{"key":"ref162","doi-asserted-by":"publisher","first-page":"146562","DOI":"10.1016\/j.brainres.2019.146562","volume":"1727","author":"Jerlhag","year":"2020","journal-title":"Brain Res"},{"key":"ref163","doi-asserted-by":"publisher","DOI":"10.1523\/ENEURO.0443-18.2019","volume":"6","author":"Bornebusch","year":"2019","journal-title":"eNeuro"},{"key":"ref164","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1038\/s41386-019-0531-4","volume":"45","author":"Zhang","year":"2020","journal-title":"Neuropsychopharmacology"},{"key":"ref165","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.1111\/dom.15459","volume":"26","author":"Lau","year":"2024","journal-title":"Diabetes Obes Metab"},{"key":"ref166","doi-asserted-by":"publisher","first-page":"103238","DOI":"10.1016\/j.dsx.2025.103238","volume":"19","author":"Di Stefano","year":"2025","journal-title":"Diabetes Metab Syndr"},{"key":"ref167","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1111\/jdi.12463","volume":"1","author":"Knudsen","year":"2016","journal-title":"J Diabetes Investig"},{"key":"ref168","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1016\/S1474-4422(20)30173-3","volume":"19","author":"Cukierman-Yaffe","year":"2020","journal-title":"Lancet Neurol"},{"key":"ref169","doi-asserted-by":"publisher","first-page":"1020","DOI":"10.1007\/s43440-021-00274-8","volume":"73","author":"Detka","year":"2021","journal-title":"Pharmacol Rep"},{"key":"ref170","doi-asserted-by":"publisher","first-page":"2505","DOI":"10.1111\/dom.15538","volume":"26","author":"Silverii","year":"2024","journal-title":"Diabetes Obes Metab"},{"key":"ref171","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.1111\/dom.12963","volume":"19","author":"O\u2019neil","year":"2017","journal-title":"Diabetes Obes Metab"},{"key":"ref172","doi-asserted-by":"publisher","first-page":"e023830","DOI":"10.1136\/bmjopen-2018-023830","volume":"8","author":"Gamble","year":"2018","journal-title":"BMJ Open"},{"key":"ref173","doi-asserted-by":"publisher","first-page":"1503","DOI":"10.3390\/brainsci13111503","volume":"13","author":"Arillotta","year":"2023","journal-title":"Brain Sci"},{"key":"ref174","doi-asserted-by":"publisher","first-page":"2428","DOI":"10.3390\/ijms24032428","volume":"24","author":"Kaewlert","year":"2023","journal-title":"Int J Mol Sci"},{"key":"ref175","doi-asserted-by":"publisher","first-page":"5505","DOI":"10.3892\/ol.2018.9284","volume":"16","author":"You","year":"2018","journal-title":"Oncol Lett"},{"key":"ref176","doi-asserted-by":"publisher","first-page":"118548","DOI":"10.1016\/j.lfs.2020.118548","volume":"262","author":"Saengboonmee","year":"2020","journal-title":"Life Sci"},{"key":"ref177","doi-asserted-by":"publisher","first-page":"4416","DOI":"10.3748\/wjg.v29.i28.4416","volume":"29","author":"Saengboonmee","year":"2023","journal-title":"World J Gastroenterol"},{"key":"ref178","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1016\/j.bja.2020.10.023","volume":"126","author":"Hulst","year":"2021","journal-title":"Br J Anaesth"},{"key":"ref179","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/j.bja.2023.02.039","volume":"131","author":"Crowley","year":"2023","journal-title":"Br J Anaesth"},{"key":"ref180","doi-asserted-by":"publisher","first-page":"922","DOI":"10.1177\/10600280211055804","volume":"56","author":"Stark","year":"2022","journal-title":"Ann Pharmacother"},{"key":"ref181","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1001\/jamasurg.2024.0111","volume":"159","author":"Sen","year":"2024","journal-title":"JAMA Surg"},{"key":"ref182","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1111\/dom.14280","volume":"23","author":"Friedrichsen","year":"2021","journal-title":"Diabetes Obes Metab"},{"key":"ref183","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1097\/ALN.0000000000004776","volume":"140","author":"Ushakumari","year":"2024","journal-title":"Anesthesiology"},{"key":"ref184","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1111\/dom.14944","volume":"25","author":"Jensterle","year":"2023","journal-title":"Diabetes Obes Metab"},{"key":"ref185","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/j.cgh.2023.11.002","volume":"22","author":"Hashash","year":"2024","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref186","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1007\/s40262-021-01012-2","volume":"60","author":"Urva","year":"2021","journal-title":"Clin Pharmacokinet"},{"key":"ref187","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1007\/s40262-022-01140-3","volume":"61","author":"Urva","year":"2022","journal-title":"Clin Pharmacokinet"},{"key":"ref188","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1111\/dom.13979","volume":"22","author":"Frias","year":"2020","journal-title":"Diabetes Obes Metab"},{"key":"ref189","doi-asserted-by":"publisher","first-page":"2180","DOI":"10.1016\/S0140-6736(18)32260-8","volume":"392","author":"Frias","year":"2018","journal-title":"Lancet"},{"key":"ref190","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/S0140-6736(21)01324-6","volume":"398","author":"Rosenstock","year":"2021","journal-title":"Lancet"},{"key":"ref191","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1056\/NEJMoa2107519","volume":"385","author":"Fr\u00edas","year":"2021","journal-title":"N Engl J Med"},{"key":"ref192","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/S0140-6736(21)01443-4","volume":"398","author":"Ludvik","year":"2021","journal-title":"Lancet"},{"key":"ref193","doi-asserted-by":"publisher","first-page":"1811","DOI":"10.1016\/S0140-6736(21)02188-7","volume":"398","author":"Del Prato","year":"2021","journal-title":"Lancet"},{"key":"ref194","doi-asserted-by":"publisher","first-page":"1631","DOI":"10.1001\/jama.2023.20294","volume":"330","author":"Rosenstock","year":"2023","journal-title":"JAMA"},{"key":"ref195","doi-asserted-by":"publisher","first-page":"1251","DOI":"10.1007\/s00125-022-05715-4","volume":"65","author":"Karagiannis","year":"2022","journal-title":"Diabetologia"},{"key":"ref196","doi-asserted-by":"publisher","first-page":"990182","DOI":"10.3389\/fcvm.2022.990182","volume":"9","author":"Yu","year":"2022","journal-title":"Front Cardiovasc Med"},{"key":"ref197","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/S2213-8587(22)00116-4","volume":"10","author":"Scheen","year":"2022","journal-title":"Lancet Diabetes Endocrinol"},{"key":"ref198","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1186\/s12933-021-01366-8","volume":"20","author":"Giugliano","year":"2021","journal-title":"Cardiovasc Diabetol"},{"key":"ref199","doi-asserted-by":"publisher","first-page":"1834","DOI":"10.1056\/NEJMoa1607141","volume":"375","author":"Marso","year":"2016","journal-title":"N Engl J Med"},{"key":"ref200","doi-asserted-by":"publisher","first-page":"1861","DOI":"10.1111\/dom.14775","volume":"24","author":"Vadher","year":"2022","journal-title":"Diabetes Obes Metab"},{"key":"ref201","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/S2213-8587(22)00070-5","volume":"10","author":"Gastaldelli","year":"2022","journal-title":"Lancet Diabetes Endocrinol"},{"key":"ref202","doi-asserted-by":"publisher","first-page":"107516","DOI":"10.1016\/j.cct.2024.107516","volume":"141","author":"Malhotra","year":"2024","journal-title":"Contemp Clin Trials"},{"key":"ref203","doi-asserted-by":"publisher","first-page":"1193","DOI":"10.1056\/NEJMoa2404881","volume":"391","author":"Malhotra","year":"2024","journal-title":"N Engl J Med"},{"key":"ref204","doi-asserted-by":"publisher","first-page":"1893","DOI":"10.1007\/s13300-025-01784-x","volume":"16","author":"Fadini","year":"2025","journal-title":"Diabetes Ther"},{"key":"ref205","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1056\/NEJMoa2410027","volume":"392","author":"Packer","year":"2025","journal-title":"N Engl J Med"},{"key":"ref206","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1016\/j.jacc.2024.11.001","volume":"85","author":"Kramer","year":"2025","journal-title":"J Am Coll Cardiol"},{"key":"ref207","doi-asserted-by":"publisher","first-page":"2909","DOI":"10.1038\/s41591-023-02597-w","volume":"29","author":"Wadden","year":"2023","journal-title":"Nat Med"},{"key":"ref208","doi-asserted-by":"publisher","first-page":"4268","DOI":"10.1111\/dom.16463","volume":"27","author":"Gibble","year":"2025","journal-title":"Diabetes Obes Metab"},{"key":"ref209","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1089\/dia.2024.0050","volume":"26","author":"Garg","year":"2024","journal-title":"Diabetes Technol Ther"},{"key":"ref210","doi-asserted-by":"publisher","first-page":"114150","DOI":"10.1016\/j.bcp.2020.114150","volume":"180","author":"Darbalaei","year":"2020","journal-title":"Biochem Pharmacol"},{"key":"ref211","doi-asserted-by":"publisher","first-page":"2215","DOI":"10.1056\/NEJMoa2411528","volume":"392","author":"Ji","year":"2025","journal-title":"N Engl J Med"},{"key":"ref212","doi-asserted-by":"publisher","first-page":"8289","DOI":"10.1038\/s41467-023-44067-4","volume":"14","author":"Ji","year":"2023","journal-title":"Nat Commun"},{"key":"ref213","doi-asserted-by":"publisher","first-page":"160","DOI":"10.2337\/dc23-1287","volume":"47","author":"Zhang","year":"2024","journal-title":"Diabetes Care"},{"key":"ref214","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.cmet.2021.12.005","volume":"34","author":"Bossart","year":"2022","journal-title":"Cell Metab"},{"key":"ref215","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1038\/s41467-022-28683-0","volume":"13","author":"Zhao","year":"2022","journal-title":"Nat Commun"},{"key":"ref216","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/S2213-8587(22)00349-7","volume":"11","author":"Scheen","year":"2023","journal-title":"Lancet Diabetes Endocrinol"},{"key":"ref217","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1080\/13543784.2017.1395020","volume":"26","author":"Scheen","year":"2017","journal-title":"Expert Opin Investig Drugs"},{"key":"ref218","doi-asserted-by":"publisher","first-page":"1781","DOI":"10.1161\/CIRCULATIONAHA.124.071689","volume":"150","author":"Neuen","year":"2024","journal-title":"Circulation"},{"key":"ref219","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1016\/j.amjms.2024.07.011","volume":"368","author":"Tuersun","year":"2024","journal-title":"Am J Med Sci"},{"key":"ref220","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/S0025-7753(14)70107-1","volume":"143","author":"Soldevila","year":"2014","journal-title":"Med Clin (Barc)"},{"key":"ref221","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics14242829","volume":"14","author":"Osei","year":"2024","journal-title":"Diagnostics (Basel)"},{"key":"ref222","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1186\/s13098-023-01198-4","volume":"15","author":"Zhou","year":"2023","journal-title":"Diabetol Metab Syndr"},{"key":"ref223","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1177\/23969873241234238","volume":"9","author":"Stefanou","year":"2024","journal-title":"Eur Stroke J"},{"key":"ref224","doi-asserted-by":"publisher","first-page":"3509","DOI":"10.2147\/DDDT.S506957","volume":"19","author":"Min","year":"2025","journal-title":"Drug Des Devel Ther"},{"key":"ref225","doi-asserted-by":"publisher","first-page":"100298","DOI":"10.1016\/j.clinme.2025.100298","volume":"25","author":"Varughese","year":"2025","journal-title":"Clin Med (Lond)"},{"key":"ref226","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1007\/s00404-024-07849-9","volume":"311","author":"Price","year":"2025","journal-title":"Arch Gynecol Obstet"},{"key":"ref227","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.140532","volume":"5","author":"Willard","year":"2020","journal-title":"JCI Insight"},{"key":"ref228","doi-asserted-by":"publisher","first-page":"1431292","DOI":"10.3389\/fendo.2024.1431292","volume":"15","author":"Liu","year":"2024","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref229","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1080\/14740338.2018.1428305","volume":"17","author":"Consoli","year":"2018","journal-title":"Expert Opin Drug Saf"},{"key":"ref230","doi-asserted-by":"publisher","first-page":"1872","DOI":"10.1111\/apt.70196","volume":"61","author":"Zafer","year":"2025","journal-title":"Aliment Pharmacol Ther"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/109155","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/109155","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T11:50:15Z","timestamp":1763725815000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/the-clinical-application-of-glp-1ras-and-glp-1gip-dual-receptor-agonis-peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":230,"URL":"https:\/\/doi.org\/10.2147\/dddt.s559919","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11]]}}}