{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T14:40:13Z","timestamp":1772548813129,"version":"3.50.1"},"reference-count":27,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s562181","type":"journal-article","created":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T10:40:12Z","timestamp":1772534412000},"page":"1-13","source":"Crossref","is-referenced-by-count":0,"title":["Development and Validation of an HPLC-MS\/MS Method for Pharmacokinetic Evaluation of Tofacitinib\/Simvastatin Compound Ointment in Rats"],"prefix":"10.2147","volume":"Volume 20","author":[{"given":"Shengnan","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenxiao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaxin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6194-541X","authenticated-orcid":true,"given":"Guofei","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3070-4186","authenticated-orcid":true,"given":"Yingjie","family":"Qi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2026,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1146\/annurev-immunol-100919-023531","volume":"38","author":"Frisoli","year":"2020","journal-title":"Annu Rev Immunol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"5225","DOI":"10.3390\/jcm13175225","volume":"13","author":"Speeckaert","year":"2024","journal-title":"J Clin Med"},{"key":"ref3","first-page":"696","volume":"78","author":"Ting","year":"2023","journal-title":"Med J Malaysia"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"4409","DOI":"10.3390\/ijms25084409","volume":"25","author":"Yamaguchi","year":"2024","journal-title":"Int J Mol Sci"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1007\/s00105-024-05467-9","volume":"76","author":"Seidel","year":"2025","journal-title":"Dermatologie"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1007\/s40291-023-00672-z","volume":"27","author":"Bia\u0142czyk","year":"2023","journal-title":"Mol Diagn Ther"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"936","DOI":"10.3390\/cells12060936","volume":"12","author":"Chang","year":"2023","journal-title":"Cells"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1111\/pcmr.13101","volume":"36","author":"Post","year":"2023","journal-title":"Pigm Cell Melanoma Res"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"2074","DOI":"10.1038\/jid.2014.241","volume":"134","author":"Qiu","year":"2014","journal-title":"J Invest Dermatol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"108670","DOI":"10.1016\/j.abb.2020.108670","volume":"696","author":"Lin","year":"2020","journal-title":"Arch Biochem Biophys"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1307","DOI":"10.1111\/jcmm.12812","volume":"20","author":"Jian","year":"2016","journal-title":"J Cell Mol Med"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"121523","DOI":"10.1016\/j.ijpharm.2022.121523","volume":"615","author":"Elhalmoushy","year":"2022","journal-title":"Int J Pharm"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"e390","DOI":"10.1111\/ijd.15330","volume":"60","author":"Hasan","year":"2021","journal-title":"Int J Dermatol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"e15969","DOI":"10.1111\/dth.15969","volume":"35","author":"Shaker","year":"2022","journal-title":"Dermatol Ther"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1007\/s00403-025-04234-7","volume":"317","author":"Zhang","year":"2025","journal-title":"Arch Dermatol Res"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/s41392-023-01468-7","volume":"8","author":"Xue","year":"2023","journal-title":"Signal Transduct Target Ther"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"103276","DOI":"10.1016\/j.autrev.2023.103276","volume":"22","author":"Benucci","year":"2023","journal-title":"Autoimmun Rev"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"790125","DOI":"10.3389\/fimmu.2021.790125","volume":"12","author":"Qi","year":"2021","journal-title":"Front Immunol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.jdermsci.2023.12.008","volume":"113","author":"Inoue","year":"2024","journal-title":"J Dermatol Sci"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1001\/jamadermatol.2015.1520","volume":"151","author":"Craiglow","year":"2015","journal-title":"JAMA Dermatol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1111\/bjd.18606","volume":"182","author":"Mobasher","year":"2020","journal-title":"Br J Dermatol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1111\/pde.14159","volume":"37","author":"Olamiju","year":"2020","journal-title":"Pediatr Dermatol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1097\/FTD.0000000000000411","volume":"39","author":"Tron","year":"2017","journal-title":"Ther Drug Monit"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.cca.2014.12.008","volume":"441","author":"Patteet","year":"2015","journal-title":"Clin Chim Acta"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1002\/pca.2906","volume":"31","author":"Nahar","year":"2020","journal-title":"Phytochem Anal"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"2865","DOI":"10.2147\/DDDT.S199362","volume":"13","author":"Mei","year":"2019","journal-title":"Drug Des Devel Ther"},{"key":"ref27","unstructured":"National Pharmacopoeia Commission. The Pharmacopoeia of the People\u2019s Republic of China. Beijing China: China Medical Science and Technology Press; 2020."}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/112635","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/112635","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T10:40:18Z","timestamp":1772534418000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/development-and-validation-of-an-hplc-msms-method-for-pharmacokinetic--peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":27,"URL":"https:\/\/doi.org\/10.2147\/dddt.s562181","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]}}}