{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T15:11:34Z","timestamp":1771081894359,"version":"3.50.1"},"reference-count":40,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DHPS"],"DOI":"10.2147\/dhps.s246050","type":"journal-article","created":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T01:06:30Z","timestamp":1594688790000},"page":"103-112","source":"Crossref","is-referenced-by-count":5,"title":["<p>Pharmaceutical Quality of Selected Metronidazole and Ciprofloxacin Infusions Marketed in South Eastern Nigeria<\/p>"],"prefix":"10.2147","volume":"Volume 12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8519-2555","authenticated-orcid":true,"given":"Angus Nnamdi","family":"Oli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6482-9163","authenticated-orcid":true,"given":"MaryRose Ukamaka","family":"Ibeabuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ifeoma Bessie","family":"Enweani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9579-7029","authenticated-orcid":true,"given":"Stephen Chijioke","family":"Emencheta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2020,7]]},"reference":[{"key":"ref1","unstructured":"Bah-Traore N. Quality assurance and safety issue of pharmaceutical products marketed in developing countries. Dissertation. Mathematisch Naturwissenschaftlichen Fakult\u00e4t, Rheinische Friedrich-Wilhelms-Universit\u00e4t Bonn vorgelegt von. 2012. https:\/\/d-nb.info\/1044082860\/34."},{"key":"ref2","doi-asserted-by":"publisher","first-page":"2197","DOI":"10.5897\/AJB2006.000-5439","volume":"6","author":"Atata","year":"2007","journal-title":"Afr J Biotechnol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1136\/pgmj.2003.010421","volume":"80","author":"Waitt","year":"2004","journal-title":"Postgrad Med J"},{"key":"ref4","unstructured":"National Clinical Guideline Centre (UK). Intravenous Fluid Therapy: intravenous Fluid Therapy in Adults in Hospital [Internet]. (NICE Clinical Guidelines, No. 174.) 5, Principles and protocols for intravenous fluid therapy. London: Royal College of Physicians (UK);Dec. 2013. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK333103\/. Accessed 26 December 2019."},{"key":"ref5","volume-title":"Peripheral Line Placement","year":"2019"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"59","DOI":"10.4103\/0300-1652.103543","volume":"53","author":"Revelas","year":"2012","journal-title":"Niger Med J"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Paut O, R\u00e9mond C, Lagier P, Fortier G, Camboulives J Severe hyponatremic encephalopathy after pediatric surgery: report of seven cases and recommendations for management and prevention. Ann Fr Anesth Reanim 2000;19:467\u2013473","DOI":"10.1016\/S0750-7658(00)00221-5"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"69","DOI":"10.4103\/ajps.AJPS_40_16","volume":"15","author":"Omoifo","year":"2018","journal-title":"Afr J Paediatr Surg"},{"key":"ref9","unstructured":"CDC. Epidemiologic notes and reports nosocomial bacteremia\u2019s associated with Intravenous Fluids therapy-USA. MMWR. 1997;46(51):1227."},{"key":"ref10","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1136\/jcp.50.5.444","volume":"50","author":"Armour","year":"1997","journal-title":"J Clin Pathol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1218","DOI":"10.1136\/bmj.304.6836.1218","volume":"304","author":"Arieff","year":"1992","journal-title":"Br Med J"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/1744-8603-5-14","volume":"5","author":"Garuba","year":"2009","journal-title":"Global Health"},{"key":"ref13","first-page":"690","volume":"84","author":"Raufu","year":"2006","journal-title":"Bull World Health Organ"},{"key":"ref14","volume-title":"Global Corruption Report","year":"2006"},{"key":"ref15","unstructured":"The British Pharmacopoeia (BP). The department of health Published by the British pharmacopeia commission, London, III, 2017."},{"key":"ref16","doi-asserted-by":"publisher","first-page":"441","DOI":"10.4314\/tjpr.v8i5.48088","volume":"8","author":"Mwambete","year":"2009","journal-title":"Trop J Pharm Res"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"National Research Council (US). Committee for the Update of the Guide for the Care and Use of Laboratory Animals. Guide for the Care and Use of Laboratory Animals. 8th ed. Washington (DC): National Academies Press (US): 2011. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK54050\/doi:10.17226\/12910.","DOI":"10.17226\/12910"},{"key":"ref18","unstructured":"Veterinary Surgeon Act Cap V3 LFN 2004, Federal Republic of Nigeria. The Care and Use of Animals for Scientific Purposes. 2014."},{"key":"ref19","unstructured":"Animal Diseases (Control) Act. Cap A17 LFN, 2004, Federal Republic of Nigeria The Care and Use of Animals for Scientific Purposes. 2004."},{"key":"ref20","unstructured":"The International Pharmacopoeia. Parenteral Preparations. 9th ed. 2016; 1\u20134."},{"key":"ref21","unstructured":"The United States Pharmacopeial Convention. U. S. Pharmacopeia-National Formulary: USP monographs: ciprofloxacin and metronidazole infusions, 2017."},{"key":"ref22","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1590\/1983-084X\/14_110","volume":"17","author":"Waltrich","year":"2015","journal-title":"Revista Brasileira De Plantas Medicinais"},{"key":"ref23","volume-title":"A Standard Laboratory Technique in Pharmaceutics and Pharmaceutical Microbiology","year":"2004"},{"key":"ref24","unstructured":"CLSI. CLSI supplements M100. 27th ed. In: Performance Standards for Antimicrobial Susceptibility Testing. Wayne, PA: Clinical and Laboratory Standards Institute; 2017; 1-15."},{"key":"ref25","doi-asserted-by":"publisher","first-page":"255","DOI":"10.9734\/JSRR\/2014\/4328","volume":"3","author":"Okoye","year":"2014","journal-title":"J Sci Res Rep"},{"key":"ref26","first-page":"3207","volume":"7","author":"Jayshree","year":"2013","journal-title":"J Pure Appl Microbio"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"148","DOI":"10.11604\/pamj.2016.24.148.9270","volume":"20;24","author":"Oli","year":"2016","journal-title":"Pan Afr Med J"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1016\/j.ajic.2009.08.015","volume":"38","author":"Macias","year":"2010","journal-title":"Am J Infect Contr"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"4801247","DOI":"10.1155\/2018\/4801247","volume":"2018","author":"Ejiofor","year":"2018","journal-title":"J Pathog"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1007\/s00228-019-02631-2","volume":"75","author":"Larmen\u00e9-Beld","year":"2019","journal-title":"Euro J Clin Pharmacol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"162","DOI":"10.4103\/2229-5151.134184","volume":"4","author":"Gahlot","year":"2014","journal-title":"Int J Crit Illn Inj Sci"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/s13049-019-0596-4","volume":"27","author":"Minasyan","year":"2019","journal-title":"Scand J Trauma Resusc Emerg Med"},{"key":"ref33","unstructured":"Sandle T Assessing non-endotoxin microbial pyrogens in relation in pharmaceutical processing. Peer Reviewed: Pharmaceutical Processing. 2015."},{"key":"ref34","doi-asserted-by":"publisher","first-page":"53913","DOI":"10.3791\/53913","volume":"111","author":"Fullerton","year":"2016","journal-title":"J Visualiz Exp"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"4","DOI":"10.3390\/antibiotics8040156","volume":"8","author":"Oli","year":"2019","journal-title":"Antibiotics (Basel)"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.165.4.2108033","volume":"165","author":"Lehr","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/s40635-018-0205-2","volume":"6","author":"Benlabed","year":"2018","journal-title":"Intensive Care Med Exp"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"H274","DOI":"10.1152\/ajpheart.01031.2006","volume":"293","author":"Contaldo","year":"2007","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"7714","DOI":"10.1038\/s41598-018-25602-6","volume":"8","author":"Perez","year":"2018","journal-title":"Sci Rep"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1186\/s40360-018-0265-7","volume":"19","author":"Leopoldino","year":"2018","journal-title":"BMC Pharmacol Toxicol"}],"container-title":["Drug, Healthcare and Patient Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=59662","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=59662","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T01:06:37Z","timestamp":1594688797000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/pharmaceutical-quality-of-selected-metronidazole-and-ciprofloxacin-inf-peer-reviewed-article-DHPS"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":40,"URL":"https:\/\/doi.org\/10.2147\/dhps.s246050","relation":{},"ISSN":["1179-1365"],"issn-type":[{"value":"1179-1365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7]]}}}