{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T04:07:21Z","timestamp":1748837241099},"reference-count":27,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DMSO"],"DOI":"10.2147\/dmso.s291612","type":"journal-article","created":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T21:07:23Z","timestamp":1626124043000},"page":"3221-3228","source":"Crossref","is-referenced-by-count":3,"title":["Serum Heparanase: A New Clinical Biomarker Involved in Senile Metabolic Inflammatory Syndrome"],"prefix":"10.2147","volume":"Volume 14","author":[{"given":"Xiu-ling","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingsong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guang-hai","family":"Mei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiantao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongyu","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyu","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaodie","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"III","given":"Chengfeng","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingchun","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinghong","family":"Tao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Houguang","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2021,7]]},"reference":[{"key":"ref1","first-page":"960","volume":"31","author":"Hu","year":"2016","journal-title":"Clinical Focus"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/j.jcjd.2013.05.008","volume":"37","author":"Wang","year":"2013","journal-title":"Can J Diabetes"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1680","DOI":"10.1007\/s00125-008-1085-x","volume":"51","author":"Irving-Rodgers","year":"2008","journal-title":"Diabetologia"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"e17312","DOI":"10.1371\/journal.pone.0017312","volume":"6","author":"Shafat","year":"2011","journal-title":"PLoS One"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/j.atherosclerosis.2010.09.003","volume":"213","author":"Baker","year":"2010","journal-title":"Atherosclerosis"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.atherosclerosis.2018.07.026","volume":"276","author":"Muhammad","year":"2018","journal-title":"Atherosclerosis"},{"key":"ref7","first-page":"139","volume":"112","author":"Colman","year":"1999","journal-title":"N Z Med J"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1097\/MCG.0000000000000116","volume":"48","author":"Review","year":"2014","journal-title":"J Clin Gastroenterol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"846","DOI":"10.5551\/jat.GL2017","volume":"25","author":"Kinoshita","year":"2018","journal-title":"J Atheroscler Thromb"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"m997","DOI":"10.1136\/bmj.m997","volume":"369","author":"Li","year":"2020","journal-title":"BMJ"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"104602","DOI":"10.1016\/j.phrs.2019.104602","volume":"152","author":"Aamir","year":"2020","journal-title":"Pharmacol Res"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"4","DOI":"10.26442\/terarkh20189054-12","volume":"90","author":"Nasonov","year":"2018","journal-title":"Terapevt Arkh"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.jhepr.2019.02.004","volume":"1","author":"Lefere","year":"2019","journal-title":"JHEP Rep"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"591","DOI":"10.2147\/DMSO.S242397","volume":"13","author":"Ma","year":"2020","journal-title":"Diabetes Metab Syndr Obes"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"4565","DOI":"10.3748\/wjg.v24.i40.4565","volume":"24","author":"Liu","year":"2018","journal-title":"World J Gastroenterol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"43521","DOI":"10.18632\/oncotarget.16575","volume":"8","author":"Sun","year":"2017","journal-title":"Oncotarget"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1302","DOI":"10.1093\/annonc\/mdp524","volume":"21","author":"Khasraw","year":"2010","journal-title":"Ann Oncol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"2307","DOI":"10.1111\/febs.12184","volume":"280","author":"Meirovitz","year":"2013","journal-title":"FEBS J"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"46229","DOI":"10.1038\/srep46229","volume":"7","author":"Digre","year":"2017","journal-title":"Sci Rep"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.lfs.2015.09.023","volume":"141","author":"Quaglio","year":"2015","journal-title":"Life Sci"},{"key":"ref21","first-page":"380","volume":"44","author":"Li","year":"2017","journal-title":"Fudan Univ J Med Sci"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1533","DOI":"10.3945\/ajcn.112.056333","volume":"98","author":"van Woudenbergh","year":"2013","journal-title":"Am J Clin Nutr"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1507\/endocrj.EJ18-0153","volume":"66","author":"Zheng","year":"2019","journal-title":"Endocr J"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1007\/s00059-019-04876-0","volume":"45","author":"Schutt","year":"2020","journal-title":"Herz"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.jdiacomp.2009.01.005","volume":"24","author":"Abdin","year":"2010","journal-title":"J Diabetes Complicat"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.1172\/JCI0214955","volume":"109","author":"Hundal","year":"2002","journal-title":"J Clin Invest"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"6267","DOI":"10.1158\/1078-0432.CCR-17-0242","volume":"23","author":"Dai","year":"2017","journal-title":"Clin Cancer Res"}],"container-title":["Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=71637","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=71637","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T21:07:28Z","timestamp":1626124048000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/serum-heparanase-a-new-clinical-biomarker-involved-in-senile-metabolic-peer-reviewed-fulltext-article-DMSO"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":27,"URL":"https:\/\/doi.org\/10.2147\/dmso.s291612","relation":{},"ISSN":["1178-7007"],"issn-type":[{"value":"1178-7007","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}