{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:16:48Z","timestamp":1783469808982,"version":"3.55.0"},"reference-count":65,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DMSO"],"DOI":"10.2147\/dmso.s300525","type":"journal-article","created":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T00:41:40Z","timestamp":1616632900000},"page":"1385-1403","source":"Crossref","is-referenced-by-count":20,"title":["Glutathione S-Transferase (GSTT1 rs17856199) and Nitric Oxide Synthase (NOS2 rs2297518) Genotype Combination as Potential Oxidative Stress-Related Molecular Markers for Type 2 Diabetes Mellitus"],"prefix":"10.2147","volume":"Volume 14","author":[{"given":"Amani MT","family":"Gusti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Safaa Y","family":"Qusti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6674-5409","authenticated-orcid":true,"given":"Suhad M","family":"Bahijri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9267-3787","authenticated-orcid":true,"given":"Eman A","family":"Toraih","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8272-7718","authenticated-orcid":true,"given":"Samia","family":"Bokhari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sami M","family":"Attallah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulwahab","family":"Alzahrani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wafaa MA","family":"Alshehri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hawazin","family":"Alotaibi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1252-8403","authenticated-orcid":true,"given":"Manal S","family":"Fawzy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2021,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"107843","DOI":"10.1016\/j.diabres.2019.107843","volume":"157","author":"Saeedi","year":"2019","journal-title":"Diabetes Res Clin Pract"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"204","DOI":"10.2174\/1573399815666190531093735","volume":"16","author":"Robert","year":"2020","journal-title":"Curr Diabetes Rev"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"55","DOI":"10.22159\/ajpcr.2018.v11i1.21657","volume":"11","author":"Elfaki","year":"2018","journal-title":"Asian J Pharm Clin Res"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.2174\/1389200221999201027200931","volume":"21","author":"Elfaki","year":"2020","journal-title":"Curr Drug Metab"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"98","DOI":"10.3390\/genes11010098","volume":"11","author":"Bakhashab","year":"2020","journal-title":"Genes"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.7150\/ijms.10001","volume":"11","author":"Wu","year":"2014","journal-title":"Int J Med Sci"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"78","DOI":"10.3390\/ijerph15010078","volume":"15","author":"Dendup","year":"2018","journal-title":"Int J Environ Res Public Health"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.redox.2013.12.001","volume":"2","author":"Banerjee","year":"2014","journal-title":"Redox Biol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"546","DOI":"10.4103\/2230-8210.183480","volume":"20","author":"Chawla","year":"2016","journal-title":"Indian J Endocrinol Metab"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"760694","DOI":"10.1155\/2014\/760694","volume":"2014","author":"Soto","year":"2014","journal-title":"Oxid Med Cell Longev"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1111\/j.1749-6632.2010.05838.x","volume":"1212","author":"Billings","year":"2010","journal-title":"Ann N Y Acad Sci"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1038\/475163a","volume":"475","author":"Bustamante","year":"2011","journal-title":"Nature"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3109\/10715762.2014.971782","volume":"49","author":"Vats","year":"2015","journal-title":"Free Radic Res"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"3425617","DOI":"10.1155\/2016\/3425617","volume":"2016","author":"Rom\u00e1n-Pintos","year":"2016","journal-title":"J Diabetes Res"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1080\/09674845.2019.1595869","volume":"76","author":"Banerjee","year":"2019","journal-title":"Br J Biomed Sci"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"e13238","DOI":"10.1111\/eci.13238","volume":"50","author":"Malik","year":"2020","journal-title":"Eur J Clin Invest"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/S0891-5849(02)00905-X","volume":"33","author":"Zelko","year":"2002","journal-title":"Free Radic Biol Med"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/1471-2350-9-30","volume":"9","author":"Flekac","year":"2008","journal-title":"BMC Med Genet"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1136\/thorax.2003.005611","volume":"59","author":"Kinnula","year":"2004","journal-title":"Thorax"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"3787268","DOI":"10.1155\/2016\/3787268","volume":"2016","author":"Nithya","year":"2016","journal-title":"Genet Res Int"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.4238\/gmr15048418","volume":"15","author":"Yang","year":"2016","journal-title":"Genet Mol Res"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1080\/15476286.2015.1122164","volume":"13","author":"Zhou","year":"2016","journal-title":"RNA Biol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1002\/dmrr.442","volume":"20","author":"Chistiakov","year":"2004","journal-title":"Diabetes Metab Res Rev"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1067\/mlc.2000.107692","volume":"136","author":"Chen","year":"2000","journal-title":"J Lab Clin Med"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0891-5849(02)01197-8","volume":"34","author":"Imai","year":"2003","journal-title":"Free Radic Biol Med"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.gene.2012.05.057","volume":"505","author":"Najafi","year":"2012","journal-title":"Gene"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"804","DOI":"10.3109\/10715762.2013.828347","volume":"47","author":"Monteiro","year":"2013","journal-title":"Free Radic Res"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1177\/1479164118820641","volume":"16","author":"Admoni","year":"2019","journal-title":"Diab Vasc Dis Res"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.ajme.2014.03.003","volume":"51","author":"Zaki","year":"2015","journal-title":"Alexandria Med J"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"3722","DOI":"10.4238\/2011.October.31.14","volume":"10","author":"Amer","year":"2011","journal-title":"Genet Mol Res"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"46","DOI":"10.5455\/dmm.20131027101207","volume":"1","author":"Vats","year":"2013","journal-title":"Dis Mol Med"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"135","DOI":"10.22088\/acadpub.BUMS.6.3.135","volume":"6","author":"Tabatabaei-Malazy","year":"2017","journal-title":"Int J Mol Cell Med"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"1188","DOI":"10.17179\/excli2017-828","volume":"16","author":"Saadat","year":"2017","journal-title":"EXCLI J"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"23","DOI":"10.3109\/13816810.2011.620057","volume":"33","author":"Santos","year":"2012","journal-title":"Ophthalmic Genet"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"1743","DOI":"10.2147\/TCRM.S93172","volume":"11","author":"Porojan","year":"2015","journal-title":"Ther Clin Risk Manag"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1007\/s11033-016-4075-y","volume":"43","author":"Pri\u0161\u010d\u00e1kov\u00e1","year":"2016","journal-title":"Mol Biol Rep"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1002\/iub.1513","volume":"68","author":"Chen","year":"2016","journal-title":"IUBMB Life"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1186\/s12944-018-0778-5","volume":"17","author":"Al-Ghamdi","year":"2018","journal-title":"Lipids Health Dis"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","volume":"18","author":"Friedewald","year":"1972","journal-title":"Clin Chem"},{"key":"ref40","unstructured":"National Institutes of H. ATP III Guidelines At-a-Glance Quick Desk Reference. NIH publication; 2001: 01\u20133305."},{"key":"ref41","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1097\/GIM.0b013e31812eece0","volume":"9","author":"Janssens","year":"2007","journal-title":"Genet Med"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s11004-005-1558-0","volume":"37","author":"Haschenburger","year":"2005","journal-title":"Math Geol"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"1928","DOI":"10.1093\/bioinformatics\/btl268","volume":"22","author":"Sol\u00e9","year":"2006","journal-title":"Bioinformatics"},{"key":"ref44","first-page":"1","volume":"5","author":"Horita","year":"2015","journal-title":"Metagene"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v025.i01","volume":"25","author":"Le","year":"2008","journal-title":"J Stat Softw"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"782","DOI":"10.3389\/fphar.2018.00782","volume":"9","author":"Ma","year":"2018","journal-title":"Front Pharmacol"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"8609213","DOI":"10.1155\/2020\/8609213","volume":"2020","author":"Yaribeygi","year":"2020","journal-title":"Oxid Med Cell Longev"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.freeradbiomed.2018.04.567","volume":"121","author":"Liu","year":"2018","journal-title":"Free Radic Biol Med"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1016\/j.ygeno.2012.04.006","volume":"99","author":"Masoodi","year":"2012","journal-title":"Genomics"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"2976","DOI":"10.1093\/nar\/gkt1249","volume":"42","author":"Kheradpour","year":"2014","journal-title":"Nucleic Acids Res"},{"key":"ref51","volume-title":"Bioinformatics for Geneticists","year":"2003"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"W452","DOI":"10.1093\/nar\/gks539","volume":"40","author":"Sim","year":"2012","journal-title":"Nucleic Acids Res"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1002\/0471142905.hg0720s76","volume":"76","author":"Adzhubei","year":"2013","journal-title":"Curr Protoc Hum Genet"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1111\/j.1365-3083.2010.02458.x","volume":"72","author":"Qidwai","year":"2010","journal-title":"Scand J Immunol"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"e46","DOI":"10.1038\/ctg.2013.17","volume":"5","author":"Dhillon","year":"2014","journal-title":"Clin Transl Gastroenterol"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"1598","DOI":"10.1089\/dna.2012.1739","volume":"31","author":"Ghattas","year":"2012","journal-title":"DNA Cell Biol"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/S1471-4914(03)00030-3","volume":"9","author":"Ioannidis","year":"2003","journal-title":"Trends Mol Med"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1038\/nbt1096","volume":"23","author":"Kelley","year":"2005","journal-title":"Nat Biotechnol"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"e7407","DOI":"10.7717\/peerj.7407","volume":"7","author":"Decharatchakul","year":"2019","journal-title":"PeerJ"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1097\/01213011-200505000-00006","volume":"15","author":"Sutton","year":"2005","journal-title":"Pharmacogenet Genomics"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.metabol.2005.04.030","volume":"55","author":"Lee","year":"2006","journal-title":"Metabolism"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"1681","DOI":"10.1016\/j.metabol.2006.08.011","volume":"55","author":"Lee","year":"2006","journal-title":"Metabolism"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"378","DOI":"10.3390\/ijms16010378","volume":"16","author":"Marseglia","year":"2014","journal-title":"Int J Mol Sci"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"842","DOI":"10.1161\/CIRCRESAHA.109.212217","volume":"106","author":"Yan","year":"2010","journal-title":"Circ Res"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"978","DOI":"10.5551\/jat.53074","volume":"27","author":"Yi","year":"2020","journal-title":"J Atheroscler Thromb"}],"container-title":["Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=67964","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=67964","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T00:41:49Z","timestamp":1616632909000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/glutathione-s-transferase-gstt1-rs17856199-and-nitric-oxide-synthase-n-peer-reviewed-article-DMSO"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":65,"URL":"https:\/\/doi.org\/10.2147\/dmso.s300525","relation":{},"ISSN":["1178-7007"],"issn-type":[{"value":"1178-7007","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3]]}}}