{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T03:00:50Z","timestamp":1790218850340,"version":"4.1.0"},"reference-count":35,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DMSO"],"DOI":"10.2147\/dmso.s312334","type":"journal-article","created":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T21:53:07Z","timestamp":1622670787000},"page":"2495-2504","source":"Crossref","is-referenced-by-count":16,"title":["Maternal Plasma Betaine in Middle Pregnancy Was Associated with Decreased Risk of GDM in Twin Pregnancy: A Cohort Study"],"prefix":"10.2147","volume":"Volume 14","author":[{"given":"Xiaoli","family":"Gong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufeng","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaona","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangyu","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2021,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/j.diabres.2013.11.003","volume":"103","author":"Guariguata","year":"2014","journal-title":"Diabetes Res Clin Pract"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3967\/bes2016.001","volume":"29","author":"Xu","year":"2016","journal-title":"Biomed Environ Sci"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1186\/s12884-018-1984-x","volume":"18","author":"Kahveci","year":"2018","journal-title":"BMC Pregnancy Childbirth"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"887","DOI":"10.3967\/bes2017.119","volume":"30","author":"Du","year":"2017","journal-title":"Biomed Environ Sci"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"3718","DOI":"10.1210\/jc.2006-0624","volume":"91","author":"Fetita","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"ref6","first-page":"B142","volume":"21","author":"Silverman","year":"1998","journal-title":"Diabetes Care"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"140","DOI":"10.3967\/bes2015.017","volume":"28","author":"Chang","year":"2015","journal-title":"Biomed Environ Sci"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"e110","DOI":"10.2337\/dc16-0825","volume":"39","author":"Retnakaran","year":"2016","journal-title":"Diabetes Care"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2018.10.027","volume":"220","author":"Hiersch","year":"2019","journal-title":"Am J Obstet Gynecol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/jdi.13441","author":"Hung","year":"2020","journal-title":"J Diabetes Investig"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1111\/1753-0407.12255","volume":"8","author":"Lai","year":"2016","journal-title":"J Diabetes"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1146\/annurev.nutr.26.061505.111156","volume":"26","author":"Zeisel","year":"2006","journal-title":"Annu Rev Nutr"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s10545-010-9088-4","volume":"34","author":"Ueland","year":"2011","journal-title":"J Inherit Metab Dis"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"902","DOI":"10.2337\/db15-1094","volume":"65","author":"Ejaz","year":"2016","journal-title":"Diabetes"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1016\/j.jbiosc.2014.03.001","volume":"118","author":"Gao","year":"2014","journal-title":"J Biosci Bioeng"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"G1068","DOI":"10.1152\/ajpgi.00249.2010","volume":"299","author":"Kathirvel","year":"2010","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"3732","DOI":"10.1021\/pr200352m","volume":"10","author":"Diaz","year":"2011","journal-title":"J Proteome Res"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"5529","DOI":"10.1210\/jc.2019-00710","volume":"104","author":"Huo","year":"2019","journal-title":"J Clin Endocrinol Metab"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1093\/ajcn\/nqy116","volume":"108","author":"Li","year":"2018","journal-title":"Am J Clin Nutr"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1186\/s12884-018-2082-9","volume":"18","author":"Santana","year":"2018","journal-title":"BMC Pregnancy Childbirth"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"e49","DOI":"10.1038\/nutd.2012.23","volume":"2","author":"Yan","year":"2012","journal-title":"Nutr Diabetes"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"676","DOI":"10.2337\/dc09-1848","volume":"33","author":"Metzger","year":"2010","journal-title":"Diabetes Care"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/1471-2288-3-21","volume":"3","author":"Barros","year":"2003","journal-title":"BMC Med Res Methodol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"m1361","DOI":"10.1136\/bmj.m1361","volume":"369","author":"Vounzoulaki","year":"2020","journal-title":"BMJ (Clinical Research Ed)"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1813","DOI":"10.3390\/jcm8111813","volume":"8","author":"Garcia","year":"2019","journal-title":"J Clin Med"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1093\/ajcn\/nqy058","volume":"108","author":"Papandreou","year":"2018","journal-title":"Am J Clin Nutr"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1283","DOI":"10.3945\/ajcn.116.137158","volume":"105","author":"Roe","year":"2017","journal-title":"Am J Clin Nutr"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1373\/clinchem.2015.250761","volume":"62","author":"Svingen","year":"2016","journal-title":"Clin Chem"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1424","DOI":"10.2337\/db15-1063","volume":"65","author":"Walford","year":"2016","journal-title":"Diabetes"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1016\/j.fct.2013.08.049","volume":"62","author":"Jung","year":"2013","journal-title":"Food Chem Toxicol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"22403","DOI":"10.1074\/jbc.M110.108514","volume":"285","author":"Jacobs","year":"2010","journal-title":"J Biol Chem"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"16187","DOI":"10.1074\/jbc.M111.303255","volume":"287","author":"Teng","year":"2012","journal-title":"J Biol Chem"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"703","DOI":"10.3945\/ajcn.115.121269","volume":"103","author":"Obeid","year":"2016","journal-title":"Am J Clin Nutr"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"888","DOI":"10.3945\/ajcn.117.157107","volume":"106","author":"Shan","year":"2017","journal-title":"Am J Clin Nutr"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.2337\/dc19-2533","volume":"43","author":"Vangipurapu","year":"2020","journal-title":"Diabetes Care"}],"container-title":["Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=70176","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=70176","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T21:53:11Z","timestamp":1622670791000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/maternal-plasma-betaine-in-middle-pregnancy-was-associated-with-decrea-peer-reviewed-fulltext-article-DMSO"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":35,"URL":"https:\/\/doi.org\/10.2147\/dmso.s312334","relation":{},"ISSN":["1178-7007"],"issn-type":[{"value":"1178-7007","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6]]}}}