{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T08:11:42Z","timestamp":1759479102874,"version":"build-2065373602"},"reference-count":59,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DMSO"],"DOI":"10.2147\/dmso.s557119","type":"journal-article","created":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T07:40:12Z","timestamp":1759477212000},"page":"3731-3750","source":"Crossref","is-referenced-by-count":0,"title":["CD44, ACAN, PLVAP, and HBEGF Emerged as Potential Biomarkers in Diabetic Retinopathy"],"prefix":"10.2147","volume":"Volume 18","author":[{"given":"Qingbo","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5312-7748","authenticated-orcid":true,"given":"Juping","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaorong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6940-671X","authenticated-orcid":true,"given":"Yan","family":"Shao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"109119","DOI":"10.1016\/j.diabres.2021.109119","volume":"183","author":"Sun","year":"2022","journal-title":"Diabet Res Clin Pract"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"e144","DOI":"10.1016\/s2214-109x(20)30489-7","volume":"9","author":"Steinmetz","year":"2021","journal-title":"Lancet Glob Health"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1077669","DOI":"10.3389\/fendo.2022.1077669","volume":"13","author":"Tan","year":"2022","journal-title":"Front Endocrinol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1172\/jci.insight.93751","author":"Duh","year":"2017","journal-title":"JCI Insight"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1016\/j.ophtha.2019.06.022","volume":"126","author":"Couturier","year":"2019","journal-title":"Ophthalmology"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1038\/npp.2012.112","volume":"38","author":"Moore","year":"2013","journal-title":"Neuropsychopharmacology"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1038\/nrg3230","volume":"13","author":"Jones","year":"2012","journal-title":"Nat Rev Genet"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1186\/s13578-022-00927-y","volume":"12","author":"Cai","year":"2022","journal-title":"Cell Biosci"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"105520","DOI":"10.1016\/j.phrs.2021.105520","volume":"170","author":"Lu","year":"2021","journal-title":"Pharmacol Res"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/s13059-015-0600-x","volume":"16","author":"Lehne","year":"2015","journal-title":"Genome Biol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1186\/s40779-022-00434-8","volume":"9","author":"Su","year":"2022","journal-title":"Mil Med Res"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1186\/s13059-017-1215-1","volume":"18","author":"Hasin","year":"2017","journal-title":"Genome Biol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1038\/nrg.2018.4","volume":"19","author":"Karczewski","year":"2018","journal-title":"Nat Rev Genet"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1080\/14712598.2018.1545836","volume":"18","author":"Whitehead","year":"2018","journal-title":"Expert Opin Biol Ther"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/s13578-017-0167-1","volume":"7","author":"Zhang","year":"2017","journal-title":"Cell Biosci"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1111\/pedi.12521","volume":"18","author":"Bansal","year":"2017","journal-title":"Pediatr Diabetes"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1167\/iovs.61.13.12","volume":"61","author":"Chen","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1167\/tvst.8.6.43","volume":"8","author":"Duraisamy","year":"2019","journal-title":"Transl Vis Sci Technol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1186\/s12916-015-0421-5","volume":"13","author":"Agardh","year":"2015","journal-title":"BMC Med"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1038\/s41392-020-00303-7","volume":"5","author":"Zhao","year":"2020","journal-title":"Signal Transduct Target Ther"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"11762","DOI":"10.1038\/s41598-017-12084-1","volume":"7","author":"Berdasco","year":"2017","journal-title":"Sci Rep"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/1868-7083-5-6","volume":"5","author":"Sundrani","year":"2013","journal-title":"Clin Clin Epigenet"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"5748","DOI":"10.1167\/iovs.16-19759","volume":"57","author":"Mishra","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"13125","DOI":"10.1096\/fj.202000380RR","volume":"34","author":"Chen","year":"2020","journal-title":"FASEB j"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1101\/gad.14.2.163","volume":"14","author":"Yu","year":"2000","journal-title":"Genes Dev"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"761","DOI":"10.3892\/ijo_00000389","volume":"35","author":"Matou-Nasri","year":"2009","journal-title":"Int J Oncol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1007\/s10059-012-2294-1","volume":"33","author":"Park","year":"2012","journal-title":"Mol Cells"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"603450","DOI":"10.3389\/fendo.2020.603450","volume":"11","author":"Zhang","year":"2020","journal-title":"Front Endocrinol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1136\/bjo.82.9.1063","volume":"82","author":"Shen","year":"1998","journal-title":"Br J Ophthalmol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1369\/0022155420952902","volume":"68","author":"Koch","year":"2020","journal-title":"J Histochem Cytochem"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.exer.2014.08.011","volume":"133","author":"Roy","year":"2015","journal-title":"Exp Eye Res"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.exer.2015.04.004","volume":"142","author":"Roy","year":"2016","journal-title":"Exp Eye Res"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/s12987-018-0109-2","volume":"15","author":"Bosma","year":"2018","journal-title":"Fluids Barriers CNS"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1016\/j.ajpath.2015.11.019","volume":"186","author":"Wisniewska-Kruk","year":"2016","journal-title":"Am J Pathol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1165\/rcmb.2022-0174OC","volume":"67","author":"Hult","year":"2022","journal-title":"Am J Respir Cell Mol Biol"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1089\/met.2019.0120","volume":"18","author":"Kim","year":"2020","journal-title":"Metab Syndr Relat Disord"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1038\/s41423-020-0412-0","volume":"17","author":"Metzemaekers","year":"2020","journal-title":"Cell Mol Immunol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1126\/science.aay5356","author":"Binet","year":"2020","journal-title":"Science"},{"key":"ref39","first-page":"1153","volume":"41","author":"Barouch","year":"2000","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1038\/nm.1959","volume":"15","author":"Kessenbrock","year":"2009","journal-title":"Nat Med"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1186\/s12964-024-01653-3","volume":"22","author":"Li","year":"2024","journal-title":"Cell Commun Signal"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1007\/s10456-024-09911-1","volume":"27","author":"Hu","year":"2024","journal-title":"Angiogenesis"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"564077","DOI":"10.3389\/fimmu.2020.564077","volume":"11","author":"Kinuthia","year":"2020","journal-title":"Front Immunol"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"1276225","DOI":"10.3389\/fendo.2023.1276225","volume":"14","author":"Yao","year":"2023","journal-title":"Front Endocrinol"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/s12951-024-02330-w","volume":"22","author":"Wang","year":"2024","journal-title":"J Nanobiotechnology"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1186\/s12964-024-01838-w","volume":"22","author":"Li","year":"2024","journal-title":"Cell Commun Signal"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"851","DOI":"10.3892\/mmr.2018.9715","volume":"19","author":"Wu","year":"2019","journal-title":"Mol Med Rep"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"874885","DOI":"10.3389\/fgene.2022.874885","volume":"13","author":"Li","year":"2022","journal-title":"Front Genet"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"576","DOI":"10.2174\/1386207325666220610122114","volume":"26","author":"Wang","year":"2023","journal-title":"Comb Chem High Throughput Screen"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1007\/s00281-008-0111-x","volume":"30","author":"Adamis","year":"2008","journal-title":"Semin Immunopathol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"1270145","DOI":"10.3389\/fendo.2023.1270145","volume":"14","author":"Sun","year":"2023","journal-title":"Front Endocrinol"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1186\/s12974-015-0368-7","volume":"12","author":"Yu","year":"2015","journal-title":"J Neuroinflammation"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1084\/jem.20022027","volume":"198","author":"Ishida","year":"2003","journal-title":"J Exp Med"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1038\/nm877","volume":"9","author":"Ishida","year":"2003","journal-title":"Nat Med"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"103921","DOI":"10.1016\/j.cellimm.2019.04.009","volume":"341","author":"Sigurdardottir","year":"2019","journal-title":"Cell Immunol"},{"key":"ref56","first-page":"2010","volume":"19","author":"Yang","year":"2015","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1038\/s41467-017-00751-w","volume":"8","author":"Deliyanti","year":"2017","journal-title":"Nat Commun"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"623","DOI":"10.4049\/jimmunol.1302181","volume":"192","author":"Han","year":"2014","journal-title":"J Immunol"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"4631290","DOI":"10.1155\/2020\/4631290","volume":"2020","author":"Liu","year":"2020","journal-title":"J Diabetes Res"}],"container-title":["Diabetes, Metabolic Syndrome and Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/107579","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/107579","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T07:40:13Z","timestamp":1759477213000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/cd44-acan-plvap-and-hbegf-emerged-as-potential-biomarkers-in-diabetic--peer-reviewed-fulltext-article-DMSO"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":59,"URL":"https:\/\/doi.org\/10.2147\/dmso.s557119","relation":{},"ISSN":["1178-7007"],"issn-type":[{"value":"1178-7007","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10]]}}}