{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T00:08:35Z","timestamp":1754093315095,"version":"3.41.2"},"reference-count":47,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HMER"],"DOI":"10.2147\/hmer.s527644","type":"journal-article","created":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T07:35:16Z","timestamp":1754033716000},"page":"61-73","source":"Crossref","is-referenced-by-count":0,"title":["The Effect of Liv.52 DS in Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD): A Pilot, Randomized, Double-Blind, Placebo-Controlled, Clinical Study"],"prefix":"10.2147","volume":"Volume 17","author":[{"given":"Umesh","family":"Jalihal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh","family":"Nanda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuldeep","family":"Katariya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Balamurugan","family":"Ramanathan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9304-646X","authenticated-orcid":true,"given":"Rajesh","family":"Kumawat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-024-02072-z","volume":"10","author":"Gan","year":"2025","journal-title":"Sig Transduct Target Ther"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1111\/liv.13301","volume":"37","author":"Bedossa","year":"2017","journal-title":"Liver Int"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"19","DOI":"10.21037\/tgh.2019.10.02","volume":"5","author":"Sharma","year":"2020","journal-title":"Transl Gastroenterol Hepatol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1291501","DOI":"10.3389\/fmed.2024.1291501","volume":"11","author":"Habibullah","year":"2024","journal-title":"Front Med Lausanne"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"16226","DOI":"10.3390\/ijms232416226","volume":"23","author":"Malnick","year":"2022","journal-title":"Int J Mol Sci"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"318","DOI":"10.37349\/edd.2023.00034","author":"Garc\u00eda-Cort\u00e9s","year":"2023","journal-title":"Explor Dig Dis"},{"key":"ref7","volume-title":"Hormonal Signaling in Biology and Medicine: Comprehensive Modern Endocrinology","year":"2020"},{"key":"ref8","volume-title":"StatPearls","year":"2023"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"10","DOI":"10.12703\/r\/12-10","volume":"12","author":"Jennison","year":"2023","journal-title":"Fac Rev"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"103043","DOI":"10.1016\/j.arcmed.2024.103043","volume":"55","author":"Amini-Salehi","year":"2024","journal-title":"Arch Med Res"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.jceh.2022.11.014","volume":"13","author":"Duseja","year":"2023","journal-title":"J Clin Exp Hepatol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.jhep.2020.03.039","volume":"73","author":"Eslam","year":"2020","journal-title":"J Hepatol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"2130","DOI":"10.1007\/s12325-021-01690-1","volume":"38","author":"Lonardo","year":"2021","journal-title":"Adv Ther"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1120621","DOI":"10.3389\/fmed.2023.1120621","volume":"10","author":"Dong","year":"2023","journal-title":"Front Med Lausanne"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1557","DOI":"10.1002\/hep.29085","volume":"65","author":"Dulai","year":"2017","journal-title":"Hepatology"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"377","DOI":"10.3390\/gastroent13040037","volume":"13","author":"Ganesh","year":"2022","journal-title":"Gastroenterol Insights"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"293","DOI":"10.3390\/gastroent14030021","volume":"14","author":"Kantharia","year":"2023","journal-title":"Gastroenterol Insights"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"e60898","DOI":"10.7759\/cureus.60898","volume":"16","author":"Shivnitwar","year":"2024","journal-title":"Cureus"},{"key":"ref19","unstructured":"WHO. The Use of the WHO-UMC System for Standardised Case Causality Assessment; 2013."},{"key":"ref20","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1080\/14786419.2010.487189","volume":"25","author":"Boga","year":"2011","journal-title":"Nat Prod Res"},{"key":"ref21","first-page":"285","volume":"6","author":"Aghel","year":"2007","journal-title":"Iran J Pharm Res World"},{"key":"ref22","first-page":"1145","volume":"11","author":"Mehmood","year":"2012","journal-title":"Iran J Pharm Res"},{"key":"ref23","first-page":"200","volume":"7","author":"Naseem","year":"2011","journal-title":"Ann Pak Inst Med Sci"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"59","DOI":"10.21608\/eajbsc.2013.16111","volume":"5","author":"Elshater","year":"2013","journal-title":"Egypt Acad J Biol Sci C Physiol Mol Biol"},{"key":"ref25","first-page":"12","volume":"2","author":"Mushtaq","year":"2013","journal-title":"EuroJ Zoolog Res"},{"key":"ref26","first-page":"143","volume":"9","author":"Patil","year":"2015","journal-title":"Int J Pharm Pharm Sci"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1002\/cbf.2867","volume":"31","author":"Shivananjappa","year":"2013","journal-title":"Cell Biochem Funct"},{"key":"ref28","first-page":"217","volume":"3","author":"Mehta","year":"2010","journal-title":"Pharmacologyonline"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"98","DOI":"10.22192\/ijarbs.2017.04.08.015","volume":"4","author":"Al-Ezzy","year":"2017","journal-title":"Int J Adv Res Biol Sci"},{"key":"ref30","first-page":"504","volume":"7","author":"Gawate","year":"2016","journal-title":"Int J Pharm Pharm Sci"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1080\/19390211.2017.1310783","volume":"15","author":"Urfi","year":"2018","journal-title":"J Diet Suppl"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/1743-422X-8-26","volume":"8","author":"Javed","year":"2011","journal-title":"Virol J"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"25","DOI":"10.5923\/j.ajmms.2012020","volume":"2","author":"Baghiani","year":"2012","journal-title":"Am J Med Sci"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"116352","DOI":"10.1016\/j.jep.2023.116352","volume":"310","author":"Kumar","year":"2023","journal-title":"J Ethnopharmacol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"2021","DOI":"10.1101\/2021.08.06.455195","volume":"8","author":"Pavan","year":"2021","journal-title":"bioRxiv"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1016\/j.phymed.2004.10.003","volume":"12","author":"Huseini","year":"2005","journal-title":"Phytomedicine"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"3777","DOI":"10.3748\/wjg.v21.i13.3777","volume":"21","author":"Takahashi","year":"2015","journal-title":"World J Gastroenterol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1016\/j.phymed.2012.08.005","volume":"19","author":"Vidyashankar","year":"2012","journal-title":"Phytomedicine"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"129","DOI":"10.15584\/ejcem.2021.2.3","volume":"19","author":"Siregar","year":"2021","journal-title":"Eur J Clin Exp Med"},{"key":"ref40","doi-asserted-by":"crossref","unstructured":"European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu; clinical practice guideline panel; chair: EASL governing board representative; panel members: EASL clinical practice guidelines on non-invasive tests for evaluation of liver disease severity and prognosis - 2021 update. J Hepatol. 2021;75(3):659\u2013689. doi:10.1016\/j.jhep.2021.05.025","DOI":"10.1016\/j.jhep.2021.05.025"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1136\/flgastro-2013-100403","volume":"5","author":"Dyson","year":"2014","journal-title":"Frontline Gastroenterol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"1797","DOI":"10.1097\/HEP.0000000000000323","volume":"77","author":"Rinella","year":"2023","journal-title":"Hepatology"},{"key":"ref43","doi-asserted-by":"crossref","unstructured":"European Association for the Study of the Liver (EASL); European Association for the Study of Diabetes (EASD); European Association for the Study of Obesity (EASO). EASL-EASD-EASO clinical practice guidelines for the management of non-alcoholic fatty liver disease. J Hepatol. 2016;64(6):1388\u20131402. doi:10.1016\/j.jhep.2015.11.004","DOI":"10.1016\/j.jhep.2015.11.004"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"21117","DOI":"10.1038\/s41598-020-78342-x","volume":"10","author":"Goyal","year":"2020","journal-title":"Sci Rep"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"S104","DOI":"10.1016\/j.jhep.2008.01.009","volume":"48","author":"de Alwis","year":"2008","journal-title":"J Hepatol"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/j.jtcme.2014.12.002","volume":"6","author":"Azeemuddin","year":"2015","journal-title":"J Tradit Complement Med"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1016\/j.dsx.2019.01.005","volume":"13","author":"Safarian","year":"2019","journal-title":"Diabetes Metab Syndr"}],"container-title":["Hepatic Medicine: Evidence and Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/105384","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/105384","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T07:35:20Z","timestamp":1754033720000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/the-effect-of-liv52-ds-in-metabolic-dysfunction-associated-fatty-liver-peer-reviewed-fulltext-article-HMER"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":47,"URL":"https:\/\/doi.org\/10.2147\/hmer.s527644","relation":{},"ISSN":["1179-1535"],"issn-type":[{"value":"1179-1535","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8]]}}}