{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T12:48:39Z","timestamp":1783687719271,"version":"3.55.0"},"reference-count":51,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IDR"],"DOI":"10.2147\/idr.s560253","type":"journal-article","created":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T14:40:13Z","timestamp":1765982413000},"page":"6747-6756","source":"Crossref","is-referenced-by-count":1,"title":["ESAT-6 Modulates Macrophage Apoptosis in Mycobacterium Tuberculosis via lncNEAT1\/miR-125b-5p\/TNF-\u03b1 Pathway"],"prefix":"10.2147","volume":"Volume 18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2122-0008","authenticated-orcid":true,"given":"Zulipikaer","family":"Abudureheman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuerhongjiang","family":"Axirejiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8182-3927","authenticated-orcid":true,"given":"Jingran","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abudushalamu","family":"Abuduwake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayiguli","family":"Alimu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiheriban","family":"Mamuti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aifang","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8711-9156","authenticated-orcid":true,"given":"Li","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"107325","DOI":"10.1016\/j.ijid.2024.107325","volume":"150","author":"Goletti","year":"2025","journal-title":"Int J Infect Dis"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1080\/17576180.2024.2349423","volume":"16","author":"Khan","year":"2024","journal-title":"Bioanalysis"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"668060","DOI":"10.3389\/fimmu.2021.668060","volume":"12","author":"Bade","year":"2021","journal-title":"Front Immunol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"597","DOI":"10.21775\/cimb.041.597","volume":"41","author":"Naeem","year":"2021","journal-title":"Curr Issues Mol Biol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1080\/1040841X.2024.2370979","volume":"51","author":"van der Klugt","year":"2025","journal-title":"Crit Rev Microbiol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"6592","DOI":"10.1038\/s41467-021-26925-1","volume":"12","author":"Pajuelo","year":"2021","journal-title":"Nat Commun"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"839","DOI":"10.3390\/pathogens12060839","volume":"12","author":"Ramon-Luing","year":"2023","journal-title":"Pathogens"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"170","DOI":"10.23749\/mdl.v111i3.9983","volume":"111","author":"Zellweger","year":"2020","journal-title":"Med Lav"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1111\/sji.12447","volume":"84","author":"Ma","year":"2016","journal-title":"Scand J Immunol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"166292","DOI":"10.1016\/j.bbadis.2021.166292","volume":"1868","author":"Zonghai","year":"2022","journal-title":"Biochim Biophys Acta Mol Basis Dis"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1007\/s11010-019-03522-x","volume":"457","author":"Lin","year":"2019","journal-title":"Mol Cell Biochem"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1111\/j.1462-5822.2007.00892.x","volume":"9","author":"Derrick","year":"2007","journal-title":"Cell Microbiol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1994","DOI":"10.1111\/cmi.12169","volume":"15","author":"Aguilo","year":"2013","journal-title":"Cell Microbiol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"2445","DOI":"10.1016\/j.febslet.2010.04.050","volume":"584","author":"Choi","year":"2010","journal-title":"FEBS Lett"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"e40836","DOI":"10.1371\/journal.pone.0040836","volume":"7","author":"Grover","year":"2012","journal-title":"PLoS One"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1276","DOI":"10.1159\/000373950","volume":"35","author":"Yang","year":"2015","journal-title":"Cell Physiol Biochem"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"5748756","DOI":"10.1155\/2022\/5748756","volume":"2022","author":"Zheng","year":"2022","journal-title":"Dis Markers"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"36","DOI":"10.3390\/ncrna7020036","volume":"7","author":"Aliperti","year":"2021","journal-title":"Noncoding RNA"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1016\/j.bbrc.2019.01.005","volume":"509","author":"Li","year":"2019","journal-title":"Biochem Biophys Res Commun"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"9529072","DOI":"10.1155\/2018\/9529072","volume":"2018","author":"Huang","year":"2018","journal-title":"Biomed Res Int"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"434","DOI":"10.2478\/raon-2019-0051","volume":"53","author":"Wang","year":"2019","journal-title":"Radiol Oncol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.3892\/ijo.2019.4869","volume":"55","author":"Xiong","year":"2019","journal-title":"Int J Oncol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"2771","DOI":"10.3892\/mmr.2017.8186","volume":"17","author":"Wang","year":"2018","journal-title":"Mol Med Rep"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1093\/abbs\/gmab055","volume":"53","author":"Dong","year":"2021","journal-title":"Acta Biochim Biophys Sin"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"3290","DOI":"10.3892\/etm.2020.9079","volume":"20","author":"Liu","year":"2020","journal-title":"Exp Ther Med"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"109157","DOI":"10.1016\/j.exer.2022.109157","volume":"222","author":"Chen","year":"2022","journal-title":"Exp Eye Res"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1002\/iub.2033","volume":"71","author":"Chen","year":"2019","journal-title":"IUBMB Life"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"7167","DOI":"10.3390\/ijms23137167","volume":"23","author":"Ptb","year":"2022","journal-title":"Int J Mol Sci"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"230","DOI":"10.3390\/ijms25010230","volume":"25","author":"Chen","year":"2023","journal-title":"Int J Mol Sci"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"309","DOI":"10.3109\/08820139.2014.914533","volume":"44","author":"Kim","year":"2015","journal-title":"Immunol Invest"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"17408","DOI":"10.1073\/pnas.1112660108","volume":"108","author":"Rajaram","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"3993","DOI":"10.1096\/fj.201701407R","volume":"32","author":"Oh","year":"2018","journal-title":"FASEB J"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"1525922","DOI":"10.3389\/fimmu.2025.1525922","volume":"16","author":"Yang","year":"2025","journal-title":"Front Immunol"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"6255","DOI":"10.3390\/ijms25116255","volume":"25","author":"Vu","year":"2024","journal-title":"Int J Mol Sci"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"e0286056","DOI":"10.1371\/journal.pone.0286056","volume":"18","author":"Liu","year":"2023","journal-title":"PLoS One"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.diff.2022.10.001","volume":"128","author":"Mohd Yasin","year":"2022","journal-title":"Differentiation"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"130425","DOI":"10.1016\/j.bbagen.2023.130425","volume":"1867","author":"Kumar","year":"2023","journal-title":"Biochim Biophys Acta Gen Subj"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"476","DOI":"10.3390\/cells12030476","volume":"12","author":"Su","year":"2023","journal-title":"Cells"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1111\/imr.12268","volume":"264","author":"Hmama","year":"2015","journal-title":"Immunol Rev"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"107283","DOI":"10.1016\/j.intimp.2020.107283","volume":"91","author":"Yang","year":"2021","journal-title":"Int Immunopharmacol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"209","DOI":"10.2174\/1566524013363933","volume":"1","author":"Mariani","year":"2001","journal-title":"Curr Mol Med"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"e01017","DOI":"10.1128\/mBio.01017-18","volume":"9","author":"Grover","year":"2018","journal-title":"mBio"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1007\/s00005-015-0365-7","volume":"64","author":"Travar","year":"2016","journal-title":"Arch Immunol Ther Exp"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3349\/ymj.2009.50.1.1","volume":"50","author":"Lee","year":"2009","journal-title":"Yonsei Med J"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"lxad104","DOI":"10.1093\/jambio\/lxad104","volume":"134","author":"Jumat","year":"2023","journal-title":"J Appl Microbiol"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/j.ijbiomac.2020.04.030","volume":"156","author":"Fathizadeh","year":"2020","journal-title":"Int J Biol Macromol"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1016\/j.ccm.2019.07.003","volume":"40","author":"Godfrey","year":"2019","journal-title":"Clin Chest Med"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"1841","DOI":"10.1007\/s10571-021-01063-w","volume":"42","author":"Zhou","year":"2022","journal-title":"Cell Mol Neurobiol"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.molimm.2021.06.025","volume":"137","author":"Kumar","year":"2021","journal-title":"Mol Immunol"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1146\/annurev-immunol-093019-010426","volume":"39","author":"Ravesloot-Ch\u00e1vez","year":"2021","journal-title":"Annu Rev Immunol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.molimm.2020.11.020","volume":"130","author":"Pattanaik","year":"2021","journal-title":"Mol Immunol"}],"container-title":["Infection and Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/110060","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/110060","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T14:40:14Z","timestamp":1765982414000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/esat-6-modulates-macrophage-apoptosis-in-mycobacterium-tuberculosis-vi-peer-reviewed-fulltext-article-IDR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":51,"URL":"https:\/\/doi.org\/10.2147\/idr.s560253","relation":{},"ISSN":["1178-6973"],"issn-type":[{"value":"1178-6973","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12]]}}}