{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T03:06:09Z","timestamp":1779073569903,"version":"3.51.4"},"reference-count":64,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IDR"],"DOI":"10.2147\/idr.s595891","type":"journal-article","created":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T02:15:13Z","timestamp":1779070513000},"page":"1-22","source":"Crossref","is-referenced-by-count":0,"title":["Multicenter Surveillance of Klebsiella pneumoniae: Resistance Shifts, CRKP Prevalence and Hypervirulent Evolution Trajectories in Hebei, China (2019-2023)"],"prefix":"10.2147","volume":"Volume 19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-7559-3143","authenticated-orcid":true,"given":"Kaiyue","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiying","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4541-7144","authenticated-orcid":true,"given":"Ziye","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3326-6600","authenticated-orcid":true,"given":"Cuixin","family":"Qiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2363-6648","authenticated-orcid":true,"given":"Jiansheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4323-7859","authenticated-orcid":true,"given":"Pu","family":"Qin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0312-9917","authenticated-orcid":true,"given":"Ziyuan","family":"Mao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8868-3687","authenticated-orcid":true,"given":"Ya","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7920-7239","authenticated-orcid":true,"given":"Zhirong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7368-7961","authenticated-orcid":true,"given":"Jianhong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2026,5]]},"reference":[{"key":"ref1","unstructured":"China Antimicrobial Resistance Surveillance System. Antimicrobial resistance of bacteria from different grades of hospitals: surveillance report from China Antimicrobial Resistance Surveillance System, 2020-2024. Chin J Infect Control. 2025;24(12):1717\u20131734. doi:10.12138\/j.issn.1671-9638.20255414"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"2658","DOI":"10.1016\/j.scib.2023.09.040","volume":"68","author":"Pu","year":"2023","journal-title":"Sci Bull"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.1017\/ice.2017.197","volume":"38","author":"Kohler","year":"2017","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"13041","DOI":"10.1038\/s41598-024-63864-5","volume":"14","author":"Ma","year":"2024","journal-title":"Sci Rep"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/s12941-025-00827-2","volume":"24","author":"Yang","year":"2025","journal-title":"Ann Clin Microbiol Antimicrob"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"814","DOI":"10.1038\/s41564-024-01612-1","volume":"9","author":"Hu","year":"2024","journal-title":"Nat Microbiol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"e0416522","DOI":"10.1128\/spectrum.04165-22","volume":"11","author":"Wang","year":"2023","journal-title":"Microbiol Spectr"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"107","DOI":"10.4161\/viru.22718","volume":"4","author":"Shon","year":"2013","journal-title":"Virulence"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1080\/17460913.2025.2576434","volume":"20","author":"Khoshnood","year":"2025","journal-title":"Future Microbiol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.jgar.2021.02.020","volume":"25","author":"Lan","year":"2021","journal-title":"J Global Antimicrob Resist"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"e02400","DOI":"10.1128\/spectrum.02400-22","volume":"10","author":"Wang","year":"2022","journal-title":"Microbiol Spectr"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/S1473-3099(17)30489-9","volume":"18","author":"Gu","year":"2018","journal-title":"Lancet Infect Dis"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"e02435","DOI":"10.1128\/AAC.02435-20","volume":"65","author":"Jin","year":"2021","journal-title":"Antimicrob Agents Chemother"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1353849","DOI":"10.3389\/fmicb.2024.1353849","volume":"15","author":"Zhang","year":"2024","journal-title":"Front Microbiol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1186\/s13073-021-00936-5","volume":"13","author":"Xu","year":"2021","journal-title":"Genome Med"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"eado9097","DOI":"10.1126\/sciadv.ado9097","volume":"11","author":"Sun","year":"2025","journal-title":"Sci Adv"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1186\/s13073-023-01260-w","volume":"15","author":"Zhang","year":"2023","journal-title":"Genome Med"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1936","DOI":"10.1080\/22221751.2022.2103454","volume":"11","author":"Tian","year":"2022","journal-title":"Emerging Microbes Infect"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"105952","DOI":"10.1016\/j.ijantimicag.2020.105952","volume":"55","author":"Li","year":"2020","journal-title":"Int J Antimicrob Agents"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"24296","DOI":"10.1038\/s41598-024-74307-6","volume":"14","author":"Yuan","year":"2024","journal-title":"Sci Rep"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"107245","DOI":"10.1016\/j.ijantimicag.2024.107245","volume":"64","author":"Wang","year":"2024","journal-title":"Int J Antimicrob Agents"},{"key":"ref22","unstructured":"China Antimicrobial Resistance Surveillance System. Changing carbapenem resistance profiles of Klebsiella pneumoniae: surveillance report from China Antimicrobial Resistance Surveillance System, 2020-2024. Chin J Infect Chemother. 2026;26(02):179\u2013185. doi:10.16718\/j.1009-7708.2026.02.011"},{"key":"ref23","unstructured":"Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility. 34th. In: Testing. M100. Wayne, PA: CLSI; 2024."},{"key":"ref24","unstructured":"The European Committee on Antimicrobial Susceptibility Testing. Breakpoint tables for interpretation of MICs and zone diameters. In: Version. Vol. 10. Stockholm: EUCAST; 2020."},{"key":"ref25","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1186\/1756-0500-5-337","volume":"5","author":"Lindgreen","year":"2012","journal-title":"BMC Res Notes"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/2047-217X-1-18","volume":"1","author":"Luo","year":"2012","journal-title":"GigaScience"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"001428","DOI":"10.1099\/mgen.0.001428","volume":"11","author":"Stanton","year":"2025","journal-title":"Microb Genomics"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"4188","DOI":"10.1038\/s41467-021-24448-3","volume":"12","author":"Lam","year":"2021","journal-title":"Nat Commun"},{"key":"ref29","doi-asserted-by":"crossref","unstructured":"GBD 2023 Causes of Death Collaborators.Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990-2023: a systematic analysis for the global burden of disease study 2023. Lancet. 2025;406(10513):1811\u20131872. doi:10.1016\/S0140-6736(25)01917-8","DOI":"10.1016\/S0140-6736(25)01917-8"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"1584574","DOI":"10.3389\/fpubh.2025.1584574","volume":"13","author":"Rozman","year":"2025","journal-title":"Front Public Health"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"5391","DOI":"10.2147\/IDR.S550953","volume":"18","author":"Du","year":"2025","journal-title":"Infect Drug Resist"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1038\/s41577-024-00996-9","volume":"24","author":"Forsyth","year":"2024","journal-title":"Nat Rev Immunol"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"e70037","DOI":"10.1002\/mbo3.70037","volume":"14","author":"Yakobi","year":"2025","journal-title":"Microbiologyopen"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"2451","DOI":"10.3390\/microorganisms13112451","volume":"13","author":"Borcan","year":"2025","journal-title":"Microorganisms"},{"key":"ref35","unstructured":"World Health Organization. Global antibiotic resistance surveillance report 2025. Available from: https:\/\/www.who.int\/publications\/i\/item\/9789240116337. Accessed May 05, 2026."},{"key":"ref36","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1016\/j.jgar.2020.03.023","volume":"22","author":"Zhao","year":"2020","journal-title":"J Global Antimicrob Resist"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.2147\/IDR.S455146","volume":"17","author":"Li","year":"2024","journal-title":"Infect Drug Resist"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1855","DOI":"10.2147\/IDR.S311968","volume":"14","author":"Chen","year":"2021","journal-title":"Infect Drug Resist"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"e0419722","DOI":"10.1128\/spectrum.04197-22","volume":"11","author":"Wang","year":"2023","journal-title":"Microbiol Spectr"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"e0009023","DOI":"10.1128\/mmbr.00090-23","volume":"89","author":"Whitfield","year":"2025","journal-title":"Microbiol Mol Biol Rev"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"e000073","DOI":"10.1099\/mgen.0.000073","volume":"2","author":"Follador","year":"2016","journal-title":"Microb Genomics"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"15573","DOI":"10.1038\/srep15573","volume":"5","author":"Pan","year":"2015","journal-title":"Sci Rep"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"289","DOI":"10.3201\/eid2602.190594","volume":"26","author":"Zhou","year":"2020","journal-title":"Emerg Infect Dis"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"101083","DOI":"10.1016\/j.drup.2024.101083","volume":"74","author":"Wang","year":"2024","journal-title":"Drug Resist Updates"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1186\/s12866-025-03888-7","volume":"25","author":"Wang","year":"2025","journal-title":"BMC Microbiol"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"121581","DOI":"10.1016\/j.carbpol.2023.121581","volume":"326","author":"Artyszuk","year":"2024","journal-title":"Carbohydr Polym"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"2464","DOI":"10.1038\/s41467-023-38061-z","volume":"14","author":"Zhou","year":"2023","journal-title":"Nat Commun"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"107154","DOI":"10.1016\/j.micpath.2024.107154","volume":"198","author":"Yan","year":"2025","journal-title":"Microbiol Pathogen"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"S196","DOI":"10.1093\/cid\/ciy660","volume":"67","author":"Wang","year":"2018","journal-title":"Clin Infect Dis"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"1380678","DOI":"10.3389\/fcimb.2024.1380678","volume":"14","author":"Li","year":"2024","journal-title":"Front Cell Infect Microbiol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"1569004","DOI":"10.3389\/fcimb.2025.1569004","volume":"15","author":"Lian","year":"2025","journal-title":"Front Cell Infect Microbiol"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1016\/S1473-3099(21)00399-6","volume":"22","author":"Wang","year":"2022","journal-title":"Lancet Infect Dis"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"101137","DOI":"10.1016\/j.drup.2024.101137","volume":"77","author":"Jia","year":"2024","journal-title":"Drug Resist Updates"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"6385","DOI":"10.2147\/IDR.S425949","volume":"16","author":"Chen","year":"2023","journal-title":"Infect Drug Resist"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"101124","DOI":"10.1016\/j.drup.2024.101124","volume":"77","author":"Liu","year":"2024","journal-title":"Drug Resist Updates"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"1325077","DOI":"10.3389\/fmicb.2023.1325077","volume":"14","author":"Mendes","year":"2023","journal-title":"Front Microbiol"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1038\/s41467-023-44351-3","volume":"15","author":"Wang","year":"2024","journal-title":"Nat Commun"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"e0110124","DOI":"10.1128\/msystems.01101-24","volume":"9","author":"Han","year":"2024","journal-title":"mSystems"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"e0054023","DOI":"10.1128\/spectrum.00540-23","volume":"11","author":"Morales-Le\u00f3n","year":"2023","journal-title":"Microbiol Spectr"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1080\/21505594.2021.1924019","volume":"12","author":"Tian","year":"2021","journal-title":"Virulence"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1186\/s12866-025-04638-5","volume":"26","author":"Zhou","year":"2025","journal-title":"BMC Microbiol"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1093\/jac\/dkz538","volume":"75","author":"Tang","year":"2020","journal-title":"J Antimicrob Chemother"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"893","DOI":"10.3390\/microorganisms8060893","volume":"8","author":"Ja\u00e9n-Luchoro","year":"2020","journal-title":"Microorganisms"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1016\/j.gpb.2022.02.005","volume":"20","author":"Li","year":"2022","journal-title":"Genomics Proteomics Bioinf"}],"container-title":["Infection and Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/115268","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/115268","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T02:15:16Z","timestamp":1779070516000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/multicenter-surveillance-of-klebsiella-pneumoniae-resistance-shifts-cr-peer-reviewed-fulltext-article-IDR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":64,"URL":"https:\/\/doi.org\/10.2147\/idr.s595891","relation":{},"ISSN":["1178-6973"],"issn-type":[{"value":"1178-6973","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]}}}