{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T14:29:59Z","timestamp":1787668199148,"version":"build-2736575974"},"reference-count":23,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IDR"],"DOI":"10.2147\/idr.s608393","type":"journal-article","created":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T14:55:23Z","timestamp":1778511323000},"page":"1-13","source":"Crossref","is-referenced-by-count":3,"title":["Combination Therapy with Ceftazidime-Avibactam, Aztreonam, and Topical Polymyxin B for NDM-Producing Klebsiella pneumoniae CNS Infection: A Case Report"],"prefix":"10.2147","volume":"Volume 19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-8792-4796","authenticated-orcid":true,"given":"Guanghong","family":"Qi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenkai","family":"Cong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingda","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengjie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenwei","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2843-1577","authenticated-orcid":true,"given":"Hongwei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/j.jsps.2015.01.001","volume":"23","author":"Zhi-Wen","year":"2015","journal-title":"Saudi Pharm J"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"675","DOI":"10.3390\/antibiotics14070675","volume":"14","author":"Chan","year":"2025","journal-title":"Antibiotics"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"13973","DOI":"10.1002\/anie.201700964","volume":"56","author":"Seeberger","year":"2017","journal-title":"Angew Chem Int Ed Engl"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1186\/s13756-018-0435-9","volume":"7","author":"Zhang","year":"2018","journal-title":"Antimicrob Resist Infect Control"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"103118","DOI":"10.1016\/j.jiph.2025.103118","volume":"19","author":"Abbas","year":"2026","journal-title":"J Infect Public Health"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"e00010","DOI":"10.1128\/AAC.00010-19","volume":"63","author":"Emeraud","year":"2019","journal-title":"Antimicrob Agents Chemother"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"9684","DOI":"10.1038\/s41598-021-89255-8","volume":"11","author":"Alghoribi","year":"2021","journal-title":"Sci Rep"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1093\/jac\/dkz495","volume":"75","author":"Sieswerda","year":"2020","journal-title":"J Antimicrob Chemother"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.jgar.2023.08.006","volume":"35","author":"Hu","year":"2023","journal-title":"J Glob Antimicrob Resist"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"3329","DOI":"10.2147\/IDR.S523271","volume":"18","author":"Xia","year":"2025","journal-title":"Infect Drug Resist"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"e0315490","DOI":"10.1371\/journal.pone.0315490","volume":"20","author":"Al-Ouqaili","year":"2025","journal-title":"PLoS One"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1515\/med-2018-0070","volume":"13","author":"Lin","year":"2018","journal-title":"Open Med"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"e0064924","DOI":"10.1128\/jcm.00649-24","volume":"62","author":"Lemon","year":"2024","journal-title":"J Clin Microbiol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"ciaf259","DOI":"10.1093\/cid\/ciaf259","author":"Balbuena","year":"2025","journal-title":"Clin Infect Dis"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"2622","DOI":"10.1093\/jac\/dkaa197","volume":"75","author":"Lodise","year":"2020","journal-title":"J Antimicrob Chemother"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1007\/s15010-023-02094-9","volume":"52","author":"Sree","year":"2024","journal-title":"Infection"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"S436","DOI":"10.1093\/cid\/ciaa1521","volume":"71","author":"Shi","year":"2020","journal-title":"Clin Infect Dis"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2021.03.001","volume":"27","author":"Venditti","year":"2021","journal-title":"Clin Microbiol Infect"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1016\/j.ajt.2023.03.011","volume":"23","author":"P\u00e9rez-Nadales","year":"2023","journal-title":"Am J Transplant"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1038\/s41467-021-27656-z","volume":"13","author":"Eskenazi","year":"2022","journal-title":"Nat Commun"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"101205","DOI":"10.1016\/j.drup.2025.101205","volume":"79","author":"Li","year":"2025","journal-title":"Drug Resist Updat"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"809","DOI":"10.2217\/fmb-2016-0042","volume":"11","author":"Karampatakis","year":"2016","journal-title":"Future Microbiol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"1604045","DOI":"10.3389\/fneur.2025.1604045","volume":"16","author":"Cong","year":"2025","journal-title":"Front Neurol"}],"container-title":["Infection and Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/115040","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/115040","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T14:55:24Z","timestamp":1778511324000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/combination-therapy-with-ceftazidime-avibactam-aztreonam-and-topical-p-peer-reviewed-fulltext-article-IDR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":23,"URL":"https:\/\/doi.org\/10.2147\/idr.s608393","relation":{},"ISSN":["1178-6973"],"issn-type":[{"value":"1178-6973","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]}}}