{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T02:33:44Z","timestamp":1790130824744,"version":"4.0.1"},"reference-count":34,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s225807","type":"journal-article","created":{"date-parts":[[2020,3,9]],"date-time":"2020-03-09T19:37:46Z","timestamp":1583782666000},"page":"1677-1691","source":"Crossref","is-referenced-by-count":63,"title":["<p>Multifunctional Immunoliposomes Combining Catalase and PD-L1 Antibodies Overcome Tumor Hypoxia and Enhance Immunotherapeutic Effects Against Melanoma<\/p>"],"prefix":"10.2147","volume":"Volume 15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8485-733X","authenticated-orcid":true,"given":"Yu","family":"Hei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BingHong","family":"Teng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ZiQian","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SiQi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JiJia","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ZuYuan","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8821-2643","authenticated-orcid":true,"given":"ChunYang","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6024-9615","authenticated-orcid":true,"given":"ShiCheng","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2020,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.phrs.2019.104258","volume":"145","author":"Shergold","year":"2019","journal-title":"Pharmacol Res"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1016\/j.cell.2016.03.031","volume":"165","author":"Minn","year":"2016","journal-title":"Cell"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1014","DOI":"10.1038\/ni.2703","volume":"14","author":"Gajewski","year":"2013","journal-title":"Nat Immunol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1172\/JCI83465","volume":"126","author":"Leisegang","year":"2016","journal-title":"J Clin Invest"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1038\/nature25187","volume":"553","author":"Eroglu","year":"2018","journal-title":"Nature"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"2375","DOI":"10.1093\/annonc\/mdv383","volume":"26","author":"Naidoo","year":"2015","journal-title":"Ann Oncol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"137","DOI":"10.2337\/dc15-0889","volume":"38","author":"Mellati","year":"2015","journal-title":"Diabetes Care"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1038\/nrclinonc.2016.58","volume":"13","author":"Boutros","year":"2016","journal-title":"Nat Rev Clin Oncol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"76","DOI":"10.14694\/EdBook_AM.2015.35.76","volume":"35","author":"Postow","year":"2015","journal-title":"Am Soc Clin Oncol Educ B"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"2092","DOI":"10.1200\/JCO.2014.60.0379","volume":"33","author":"Weber","year":"2015","journal-title":"J Clin Oncol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1038\/nature13904","volume":"515","author":"Powles","year":"2014","journal-title":"Nature"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1152\/ajpcell.00207.2015","volume":"309","author":"Noman","year":"2015","journal-title":"Am J Physiol Cell Physiol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1016\/j.coi.2013.02.009","volume":"25","author":"Gajewski","year":"2013","journal-title":"Curr Opin Immunol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s12032-013-0698-1","volume":"30","author":"Shi","year":"2013","journal-title":"Med Oncol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1152\/ajpcell.00204.2015","volume":"309","author":"Tao","year":"2015","journal-title":"Am J Physiol Cell Physiol"},{"key":"ref16","first-page":"1","volume":"32","author":"Zhang","year":"2016","journal-title":"Front Immunol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1038\/onc.2016.225","volume":"36","author":"Chouaib","year":"2017","journal-title":"Oncogene"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"6110","DOI":"10.1002\/adma.201503006","volume":"27","author":"Song","year":"2015","journal-title":"Adv Mater"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.msec.2014.04.049","volume":"41","author":"Felice","year":"2015","journal-title":"Mater Sci Eng C Mater Biol Appl"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"4361","DOI":"10.2174\/092986709789712916","volume":"16","author":"Fanciullino","year":"2009","journal-title":"Curr Med Chem"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.addr.2012.09.037","volume":"65","author":"Allen","year":"2013","journal-title":"Adv Drug Deliv Rev"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1021\/nn5062029","volume":"9","author":"Shao","year":"2015","journal-title":"ACS Nano"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1016\/j.jconrel.2018.08.011","volume":"286","author":"Zili","year":"2018","journal-title":"J Control Release"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/978-1-4939-6591-5_2","volume":"1522","author":"Hongwei","year":"2017","journal-title":"Methods Mol Biol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/j.jconrel.2015.10.044","volume":"220","author":"Arabi","year":"2015","journal-title":"J Control Release"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"17","DOI":"10.2147\/IJN.S175340","volume":"14","author":"Xu","year":"2019","journal-title":"Int J Nanomedicine"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"7143","DOI":"10.1002\/adma.201602111","volume":"28","author":"Song","year":"2016","journal-title":"Adv Mater"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/0009-8981(91)90067-M","volume":"196","author":"Goth","year":"1991","journal-title":"Clin Chim Acta"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"81","DOI":"10.7150\/thno.7193","volume":"4","author":"Kobayashi","year":"2014","journal-title":"Theranostics"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.drudis.2012.11.005","volume":"18","author":"Southan","year":"2013","journal-title":"Drug Discov Today"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.biomaterials.2017.05.025","volume":"138","author":"Zhang","year":"2017","journal-title":"Biomaterials"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"2508","DOI":"10.1016\/j.biomaterials.2011.11.078","volume":"33","author":"Zhao","year":"2012","journal-title":"Biomaterials"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.bbamem.2004.01.006","volume":"1663","author":"Cevc","year":"2004","journal-title":"BBA-Biomembranes"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/0005-2736(91)90385-L","volume":"1062","author":"Klibanov","year":"1991","journal-title":"Biochim Biophys Acta"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=56690","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=56690","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,11]],"date-time":"2020-03-11T22:21:36Z","timestamp":1583965296000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/multifunctional-immunoliposomes-combining-catalase-and-pd-l1-antibodie-peer-reviewed-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":34,"URL":"https:\/\/doi.org\/10.2147\/ijn.s225807","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3]]}}}