{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T17:03:05Z","timestamp":1790442185156,"version":"4.1.0"},"reference-count":59,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s245608","type":"journal-article","created":{"date-parts":[[2020,6,29]],"date-time":"2020-06-29T20:52:25Z","timestamp":1593463945000},"page":"4659-4676","source":"Crossref","is-referenced-by-count":73,"title":["&lt;p&gt;Involvement of FAK\/P38 Signaling Pathways in Mediating the Enhanced Osteogenesis Induced by Nano-Graphene Oxide Modification on Titanium Implant Surface&lt;\/p&gt;"],"prefix":"10.2147","volume":"Volume 15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4358-3934","authenticated-orcid":true,"given":"Qingfan","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuolin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2020,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.jpor.2014.11.007","volume":"59","author":"Shibata","year":"2015","journal-title":"J Prosthodont Res"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1007\/s00784-013-0953-z","volume":"18","author":"Gil","year":"2014","journal-title":"Clin Oral Investig"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.mser.2004.11.001","volume":"47","author":"Liu","year":"2004","journal-title":"Mater Sci Eng R Rep"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.bbrc.2015.02.157","volume":"460","author":"Li","year":"2015","journal-title":"Biochem Biophys Res Commun"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"6268","DOI":"10.1016\/j.actbio.2012.12.002","volume":"9","author":"Gittens","year":"2013","journal-title":"Acta Biomater"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1021\/acsbiomaterials.6b00604","volume":"3","author":"Civantos","year":"2017","journal-title":"ACS Biomater Sci Eng"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1039\/C5TB02190A","volume":"4","author":"Yu","year":"2016","journal-title":"J Mater Chem B"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1586\/erd.09.74","volume":"7","author":"Elias","year":"2010","journal-title":"Expert Rev Med Devices"},{"key":"ref9","first-page":"63","volume":"25","author":"Wennerberg","year":"2010","journal-title":"Int J Oral Maxillofac Implants"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1016\/j.dental.2006.06.025","volume":"23","author":"Le Guehennec","year":"2007","journal-title":"Dent Mater"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1594","DOI":"10.1038\/nm.2542","volume":"17","author":"Liu","year":"2011","journal-title":"Nat Med"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"2834","DOI":"10.1016\/j.actbio.2014.02.002","volume":"10","author":"Yoshizawa","year":"2014","journal-title":"Acta Biomater"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"356","DOI":"10.4162\/nrp.2010.4.5.356","volume":"4","author":"Seo","year":"2010","journal-title":"Nutr Res Pract"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.pharmthera.2012.07.009","volume":"136","author":"Saidak","year":"2012","journal-title":"Pharmacol Ther"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"3184","DOI":"10.1016\/j.biomaterials.2013.01.008","volume":"34","author":"Zhang","year":"2013","journal-title":"Biomaterials"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1406","DOI":"10.1016\/j.progpolymsci.2014.01.001","volume":"39","author":"Tejero","year":"2014","journal-title":"Prog Polym Sci"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1016\/j.apmt.2017.12.004","volume":"10","author":"Miszuk","year":"2018","journal-title":"Appl Mater Today"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"9","DOI":"10.2147\/IJN.S88285","volume":"10","author":"Wu","year":"2015","journal-title":"Int J Nanomedicine"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"2258","DOI":"10.1002\/adma.201203700","volume":"25","author":"Bitounis","year":"2013","journal-title":"Adv Mater"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"1927","DOI":"10.2147\/IJN.S105264","volume":"11","author":"Gurunathan","year":"2016","journal-title":"Int J Nanomedicine"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.addr.2016.03.007","volume":"105","author":"Shin","year":"2016","journal-title":"Adv Drug Deliv Rev"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1002\/adma.201003669","volume":"23","author":"Kim","year":"2011","journal-title":"Adv Mater"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"3432","DOI":"10.1016\/j.actbio.2011.05.019","volume":"7","author":"Depan","year":"2011","journal-title":"Acta Biomater"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"8484","DOI":"10.1039\/C4CC02442G","volume":"50","author":"Tatavarty","year":"2014","journal-title":"Chem Commun (Camb)"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"7334","DOI":"10.1021\/nn202190c","volume":"5","author":"Lee","year":"2011","journal-title":"ACS Nano"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"9243","DOI":"10.1016\/j.actbio.2013.08.016","volume":"9","author":"Liu","year":"2013","journal-title":"Acta Biomater"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1365","DOI":"10.1517\/17425247.2012.729575","volume":"9","author":"Pan","year":"2012","journal-title":"Expert Opin Drug Deliv"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1002\/mame.201000307","volume":"296","author":"Rana","year":"2011","journal-title":"Macromol Mater Eng"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"5901","DOI":"10.2147\/IJN.S37397","volume":"7","author":"Gurunathan","year":"2012","journal-title":"Int J Nanomedicine"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"549","DOI":"10.2147\/IJN.S75768","volume":"10","author":"Nanda","year":"2015","journal-title":"Int J Nanomedicine"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"2886","DOI":"10.1039\/C4CC07836E","volume":"51","author":"Mangadlao","year":"2015","journal-title":"Chem Commun (Camb)"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"6659","DOI":"10.2147\/IJN.S92110","volume":"10","author":"Zhu","year":"2015","journal-title":"Int J Nanomedicine"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"9598","DOI":"10.1021\/acsami.5b03431","volume":"7","author":"Jung","year":"2015","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"4051","DOI":"10.1002\/smll.201300571","volume":"9","author":"La","year":"2013","journal-title":"Small"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"2518","DOI":"10.1039\/C8TB02850H","volume":"7","author":"Zhang","year":"2019","journal-title":"J Mater Chem B"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1039\/C7BM01044C","volume":"6","author":"Zhang","year":"2018","journal-title":"Biomater Sci"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/j.apsusc.2012.07.033","volume":"259","author":"Parsikia","year":"2012","journal-title":"Appl Surf Sci"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"3465","DOI":"10.1007\/s10856-008-3505-3","volume":"19","author":"He","year":"2008","journal-title":"J Mater Sci Mater Med"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/j.surfcoat.2012.03.037","volume":"231","author":"Hung","year":"2013","journal-title":"Surf Coat Technol"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"13053","DOI":"10.1021\/acsami.5b03209","volume":"7","author":"Cheng","year":"2015","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"12253","DOI":"10.1021\/acsami.7b00314","volume":"9","author":"Qiu","year":"2017","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1021\/nl071822y","volume":"8","author":"Kudin","year":"2008","journal-title":"Nano Lett"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"33835","DOI":"10.1038\/srep33835","volume":"6","author":"Jeong","year":"2016","journal-title":"Sci Rep"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"3906","DOI":"10.1002\/adma.201001068","volume":"22","author":"Zhu","year":"2010","journal-title":"Adv Mater"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1111\/clr.12146","volume":"25","author":"Bang","year":"2014","journal-title":"Clin Oral Implants Res"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"17151","DOI":"10.1021\/acsami.6b05198","volume":"8","author":"Jia","year":"2016","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"4987","DOI":"10.1021\/nn507149w","volume":"9","author":"Park","year":"2015","journal-title":"ACS Nano"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"2787","DOI":"10.1016\/j.biomaterials.2013.01.001","volume":"34","author":"Yang","year":"2013","journal-title":"Biomaterials"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"7022","DOI":"10.1016\/j.biomaterials.2014.04.066","volume":"35","author":"Kanakia","year":"2014","journal-title":"Biomaterials"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"7031","DOI":"10.2147\/IJN.S90343","volume":"10","author":"Mao","year":"2015","journal-title":"Int J Nanomedicine"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"8008","DOI":"10.1021\/am402089w","volume":"5","author":"Lin","year":"2013","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1016\/S0248-4900(00)01101-1","volume":"92","author":"Petit","year":"2000","journal-title":"Biol Cell"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/S0955-0674(99)00067-8","volume":"12","author":"Critchley","year":"2000","journal-title":"Curr Opin Cell Biol"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"7615","DOI":"10.1021\/acsami.8b21558","volume":"11","author":"Wang","year":"2019","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.yexcr.2006.09.013","volume":"313","author":"Salasznyk","year":"2007","journal-title":"Exp Cell Res"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1038\/nrm1549","volume":"6","author":"Mitra","year":"2005","journal-title":"Nat Rev Mol Cell Biol"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1016\/j.lfs.2011.08.013","volume":"89","author":"So","year":"2011","journal-title":"Life Sci"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"14845","DOI":"10.1074\/jbc.M606695200","volume":"282","author":"Slack-Davis","year":"2007","journal-title":"J Biol Chem"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/S0165-6147(00)01865-4","volume":"23","author":"English","year":"2002","journal-title":"Trends Pharmacol Sci"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=59284","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=59284","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,29]],"date-time":"2020-06-29T20:52:27Z","timestamp":1593463947000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/involvement-of-fakp38-signaling-pathways-in-mediating-the-enhanced-ost-peer-reviewed-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":59,"URL":"https:\/\/doi.org\/10.2147\/ijn.s245608","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6]]}}}