{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T02:08:06Z","timestamp":1773799686141,"version":"3.50.1"},"reference-count":53,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s247252","type":"journal-article","created":{"date-parts":[[2020,4,15]],"date-time":"2020-04-15T02:20:52Z","timestamp":1586917252000},"page":"2529-2539","source":"Crossref","is-referenced-by-count":25,"title":["<p>Pumpkin Oil\u2013Based Nanostructured Lipid Carrier System for Antiulcer Effect in NSAID-Induced Gastric Ulcer Model in Rats<\/p>"],"prefix":"10.2147","volume":"Volume 15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3204-381X","authenticated-orcid":true,"given":"Osama AA","family":"Ahmed","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Usama A","family":"Fahmy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rana","family":"Bakhaidar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed A","family":"El-Moselhy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed A","family":"Alfaleh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9875-6399","authenticated-orcid":true,"given":"Al-Shaimaa F","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8655-6656","authenticated-orcid":true,"given":"Asmaa SA","family":"Hammad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hibah","family":"Aldawsari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3826-1519","authenticated-orcid":true,"given":"Nabil A","family":"Alhakamy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2020,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1155\/2006\/175217","volume":"20","author":"Zapata-Colindres","year":"2006","journal-title":"Can J Gastroenterol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"7515692","DOI":"10.1155\/2018\/7515692","volume":"2018","author":"Fazalda","year":"2018","journal-title":"Evidence-Based Complement Altern Med"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"2147","DOI":"10.3748\/wjg.v18.i18.2147","volume":"18","author":"Takeuchi","year":"2012","journal-title":"World J Gastroenterol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-018-22727-6","volume":"8","author":"Shahin","year":"2018","journal-title":"Sci Rep"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2019\/4605748","volume":"2019","author":"Fang","year":"2019","journal-title":"Biomed Res Int"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1053\/gast.2000.16510","volume":"119","author":"Wallace","year":"2000","journal-title":"Gastroenterology"},{"key":"ref7","first-page":"1131","volume":"167","author":"Wright","year":"2002","journal-title":"CMAJ"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"13049","DOI":"10.3390\/ijms131013049","volume":"13","author":"Zainol","year":"2012","journal-title":"Int J Mol Sci"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/S2468-1253(18)30037-2","volume":"3","author":"Scally","year":"2018","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"30","DOI":"10.3390\/foods7030030","volume":"7","author":"Montesano","year":"2018","journal-title":"Foods"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1730","DOI":"10.1002\/jsfa.7279","volume":"96","author":"Siano","year":"2016","journal-title":"J Sci Food Agric"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2013\/136932","volume":"2013","author":"Farzaei","year":"2013","journal-title":"ISRN Gastroenterol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1016\/j.foodres.2011.03.016","volume":"44","author":"Adams","year":"2011","journal-title":"Food Res Int"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-016-0237-0","volume":"15","author":"Bardaa","year":"2016","journal-title":"Lipids Health Dis"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1007\/s11130-006-0016-6","volume":"61","author":"Caili","year":"2006","journal-title":"Plant Foods Hum Nutr"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1002\/ejlt.200390055","volume":"105","author":"Fruhwirth","year":"2003","journal-title":"Eur J Lipid Sci Technol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"4005","DOI":"10.1021\/jf0706979","volume":"55","author":"Stevenson","year":"2007","journal-title":"J Agric Food Chem"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"9539","DOI":"10.1166\/jnn.2015.10880","volume":"15","author":"Zhu","year":"2015","journal-title":"J Nanosci Nanotechnol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1016\/j.addr.2003.12.002","volume":"56","author":"Wissing","year":"2004","journal-title":"Adv Drug Deliv Rev"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1016\/j.tips.2009.08.004","volume":"30","author":"Malam","year":"2009","journal-title":"Trends Pharmacol Sci"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/S0939-6411(00)00087-4","volume":"50","author":"M\u00fcller","year":"2000","journal-title":"Eur J Pharm Biopharm"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"683","DOI":"10.2147\/ijn.s17386","volume":"6","author":"Hao","year":"2011","journal-title":"Int J Nanomedicine"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1016\/j.addr.2007.04.007","volume":"59","author":"Almeida","year":"2007","journal-title":"Adv Drug Deliv Rev"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"349","DOI":"10.4103\/0250-474X.57282","volume":"71","author":"Mukherjee","year":"2009","journal-title":"Indian J Pharm Sci"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1007\/s13197-017-2937-5","volume":"55","author":"Akhoond Zardini","year":"2018","journal-title":"J Food Sci Technol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1016\/j.jddst.2019.04.019","volume":"52","author":"Khan","year":"2019","journal-title":"J Drug Deliv Sci Technol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"691","DOI":"10.3109\/10717544.2014.898110","volume":"22","author":"Gaba","year":"2015","journal-title":"Drug Deliv"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.ijpharm.2007.05.060","volume":"346","author":"Joshi","year":"2008","journal-title":"Int J Pharm"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1016\/j.ijpharm.2011.05.044","volume":"415","author":"Tiwari","year":"2011","journal-title":"Int J Pharm"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"305","DOI":"10.15171\/apb.2015.043","volume":"5","author":"Naseri","year":"2015","journal-title":"Adv Pharm Bull"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"6539","DOI":"10.2147\/IJN.S208489","volume":"14","author":"Lee","year":"2019","journal-title":"Int J Nanomedicine"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1016\/j.biopha.2018.04.055","volume":"103","author":"Khosa","year":"2018","journal-title":"Biomed Pharmacother"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"2125","DOI":"10.1002\/jbm.a.34890","volume":"102","author":"Aboutaleb","year":"2014","journal-title":"J Biomed Mater Res - Part A"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"586","DOI":"10.3390\/ijms19020586","volume":"19","author":"Serini","year":"2018","journal-title":"Int J Mol Sci"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"13340","DOI":"10.3390\/molecules181113340","volume":"18","author":"Zhang","year":"2013","journal-title":"Molecules"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1691\/ph.2009.9084","volume":"64","author":"Muchow","year":"2009","journal-title":"Pharmazie"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.jddst.2017.06.013","volume":"42","author":"Beloqui","year":"2017","journal-title":"J Drug Deliv Sci Technol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/J.EJPB.2013.08.013","volume":"86","author":"Weber","year":"2014","journal-title":"Eur J Pharm Biopharm"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"15802","DOI":"10.1038\/s41598-018-34235-8","volume":"8","author":"Ahmed","year":"2018","journal-title":"Sci Rep"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/0002-9343(89)90153-8","volume":"86","author":"Szabo","year":"1989","journal-title":"Am J Med"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/0003-2697(78)90342-1","volume":"86","author":"Mihara","year":"1978","journal-title":"Anal Biochem"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/0003-2697(82)90118-X","volume":"126","author":"Green","year":"1982","journal-title":"Anal Biochem"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1093\/clinchem\/26.2.227","volume":"26","author":"Fossati","year":"1980","journal-title":"Clin Chem"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.jbiotec.2004.06.007","volume":"113","author":"Muller","year":"2004","journal-title":"J Biotechnol"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"2467","DOI":"10.2147\/DDDT.S104395","volume":"10","author":"Pinheiro","year":"2016","journal-title":"Drug Des Devel Ther"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"143","DOI":"10.15171\/apb.2016.021","volume":"6","author":"Bahari","year":"2016","journal-title":"Adv Pharm Bull"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"7461","DOI":"10.2147\/IJN.S224611","volume":"14","author":"El-Say","year":"2019","journal-title":"Int J Nanomedicine"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.ejps.2012.05.010","volume":"47","author":"Das","year":"2012","journal-title":"Eur J Pharm Sci"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"1308","DOI":"10.3109\/03639045.2015.1132226","volume":"42","author":"Song","year":"2016","journal-title":"Drug Dev Ind Pharm"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2019\/1568720","volume":"2019","author":"Kh\u00e9miri","year":"2019","journal-title":"Oxid Med Cell Longev"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.3748\/wjg.v21.i5.1377","volume":"21","author":"Tovey","year":"2015","journal-title":"World J Gastroenterol"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1016\/j.jddst.2019.05.009","volume":"52","author":"Sindi","year":"2019","journal-title":"J Drug Deliv Sci Technol"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"1265","DOI":"10.1002\/ptr.4865","volume":"27","author":"Tovey","year":"2013","journal-title":"Phytother Res"}],"updated-by":[{"DOI":"10.2147\/ijn.s419017","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T00:00:00Z","timestamp":1682640000000},"record-id":"44537"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=57390","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=57390","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,15]],"date-time":"2020-04-15T02:20:55Z","timestamp":1586917255000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/pumpkin-oilndashbased-nanostructured-lipid-carrier-system-for-antiulce-peer-reviewed-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":53,"URL":"https:\/\/doi.org\/10.2147\/ijn.s247252","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4]]}}}