{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T03:38:23Z","timestamp":1784432303131,"version":"3.55.0"},"reference-count":70,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s250047","type":"journal-article","created":{"date-parts":[[2020,7,28]],"date-time":"2020-07-28T21:48:43Z","timestamp":1595972923000},"page":"5417-5432","source":"Crossref","is-referenced-by-count":58,"title":["&lt;p&gt;The Potential Anticancer Activity of 5-Fluorouracil Loaded in Cellulose Fibers Isolated from Rice Straw&lt;\/p&gt;"],"prefix":"10.2147","volume":"Volume 15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0512-5078","authenticated-orcid":true,"given":"Mostafa","family":"Yusefi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3955-4604","authenticated-orcid":true,"given":"Kamyar","family":"Shameli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7035-1963","authenticated-orcid":true,"given":"Hossein","family":"Jahangirian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3824-0224","authenticated-orcid":true,"given":"Sin-Yeang","family":"Teow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Umakoshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4930-5094","authenticated-orcid":true,"given":"Bahram","family":"Saleh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1571-9822","authenticated-orcid":true,"given":"Roshanak","family":"Rafiee-moghaddam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2028-5969","authenticated-orcid":true,"given":"Thomas J","family":"Webster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2020,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1007\/s10924-017-0963-z","volume":"26","author":"Yusefi","year":"2018","journal-title":"J Polym Environ"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"025302","DOI":"10.1088\/2053-1591\/aa5cdb","volume":"4","author":"Yusefi","year":"2017","journal-title":"Mater Res Express"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.agwat.2013.06.011","volume":"128","author":"Ram","year":"2013","journal-title":"Agric Water Manag"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.conbuildmat.2015.01.035","volume":"79","author":"Ardanuy","year":"2015","journal-title":"Constr Build Mater"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"23761","DOI":"10.1038\/srep2376","volume":"6","author":"Kim","year":"2016","journal-title":"Sci Rep"},{"key":"ref6","volume-title":"Bacterial Nanocellulose: A Sophisticated Multifunctional Material","year":"2013"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"4164","DOI":"10.1016\/j.biortech.2009.04.005","volume":"100","author":"Cai","year":"2009","journal-title":"Bioresour Technol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1007\/s10570-007-9145-9","volume":"15","author":"Mor\u00e1n","year":"2008","journal-title":"Cellulose"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1705","DOI":"10.1002\/app.2010","volume":"82","author":"Lim","year":"2001","journal-title":"J Appl Polym Sci"},{"key":"ref10","doi-asserted-by":"publisher","volume-title":"Extraction of Cellulose Nanofibers and Their Eco\/Friendly Polymer Composites","year":"2019","DOI":"10.1007\/978-3-030-05399-4_23"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"394","DOI":"10.3322\/caac.21492","volume":"68","author":"Bray","year":"2018","journal-title":"CA Cancer J Clin"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"9","DOI":"10.3390\/diagnostics10010009","volume":"10","author":"Pang","year":"2020","journal-title":"Diagnostics"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1053\/j.gastro.2004.06.050","volume":"127","author":"Kiesslich","year":"2004","journal-title":"Gastroenterology"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1884","DOI":"10.1002\/ijc.24567","volume":"125","author":"Lui","year":"2009","journal-title":"Int J Cancer"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"7591","DOI":"10.2147\/OTT.S176002","volume":"11","author":"Yu","year":"2018","journal-title":"Onco Targets Ther"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1633","DOI":"10.2147\/IJN.S184723","volume":"14","author":"Jahangirian","year":"2019","journal-title":"Int J Nanomedicine"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1080\/00914037.2013.854225","volume":"63","author":"Anirudhan","year":"2014","journal-title":"Int J Polym Mater Pol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"4895","DOI":"10.1002\/pola.26317","volume":"50","author":"Jung","year":"2012","journal-title":"J Polym Sci Pol Chem"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"619","DOI":"10.3390\/biom9100619","volume":"9","author":"Jahangirian","year":"2019","journal-title":"Biomolecules"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1186\/s12885-019-5834-7","volume":"19","author":"Song","year":"2019","journal-title":"BMC Cancer"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1016\/j.cej.2019.03.216","volume":"370","author":"Zhang","year":"2019","journal-title":"Chem Eng J"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.carbpol.2016.05.028","volume":"150","author":"HPS AK","year":"2016","journal-title":"Carbohydr Polym"},{"key":"ref23","doi-asserted-by":"publisher","volume-title":"Applications of Targeted Nano Drugs and Delivery Systems","year":"2019","DOI":"10.1016\/B978-0-12-814029-1.00018-1"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"217","DOI":"10.4103\/2278-344X.107832","volume":"1","author":"Jawahar","year":"2012","journal-title":"Int J Res Health Allied Sci"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.ijpharm.2015.01.020","volume":"480","author":"Bae","year":"2015","journal-title":"Int J Pharm"},{"key":"ref26","doi-asserted-by":"publisher","volume-title":"Multifunctional Systems for Combined Delivery, Biosensing and Diagnostics","year":"2017","DOI":"10.1016\/B978-0-323-52725-5.00013-7"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.jconrel.2013.01.026","volume":"167","author":"Li","year":"2013","journal-title":"J Control Release"},{"key":"ref28","first-page":"6387","volume":"46","author":"Matsumura","year":"1986","journal-title":"Cancer Res"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"11979","DOI":"10.1039\/C7NJ01745F","volume":"41","author":"Anirudhan","year":"2017","journal-title":"New J Chem"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1200\/JCO.2011.38.9650","volume":"30","author":"Meyerhardt","year":"2012","journal-title":"J Clin Oncol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1634\/theoncologist.2016-0215","volume":"22","author":"Niedzwiecki","year":"2017","journal-title":"Oncologist"},{"key":"ref32","first-page":"12","volume":"2","author":"Fearnhead","year":"2017","journal-title":"Drug Target Rev"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"645","DOI":"10.3109\/02841869209083847","volume":"31","author":"Glimelius","year":"1992","journal-title":"Acta Oncol"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1016\/S1542-3565(04)00293-9","volume":"2","author":"\u00d6sterlund","year":"2004","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"160","DOI":"10.4103\/njms.NJMS_27_18","volume":"9","author":"Srivastava","year":"2018","journal-title":"Natl J Maxillofac Surg"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1080\/02652040701281365","volume":"24","author":"Rokhade","year":"2007","journal-title":"J Microencapsul"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"7763","DOI":"10.15376\/biores.14.4.7763-7774","volume":"14","author":"Zheng","year":"2019","journal-title":"Bioresources"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1007\/s10570-009-9334-9","volume":"16","author":"Abe","year":"2009","journal-title":"Cellulose"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1080\/00914037.2013.854225","volume":"355","author":"Anirudhan","year":"2015","journal-title":"Int J Polym Mater"},{"key":"ref40","unstructured":"abm. Immortalized Human Nasopharyngeal Epithelial Cells (NP460) \u2013 hTERT; 2019. Available from: https:\/\/www.abmgood.com\/Immortalized-Human-Nasopharyngeal-Epithelial-Cells-(NP460)-hTERT-T0635.html. Accessed July 18, 2020."},{"key":"ref41","doi-asserted-by":"publisher","first-page":"9524","DOI":"10.1073\/pnas.86.23.9524","volume":"86","author":"Glaser","year":"1989","journal-title":"Proc Natl Acad Sci"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"2169","DOI":"10.1002\/ijc.23374","volume":"122","author":"Chan","year":"2008","journal-title":"Int J Cancer"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"109899","DOI":"10.1016\/j.msec.2019.109899","volume":"104","author":"Ismail","year":"2019","journal-title":"Mater Sci Eng C"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.molstruc.2019.04.026","volume":"1189","author":"Sukri","year":"2019","journal-title":"J Mol Struct"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"127539","DOI":"10.1016\/j.molstruc.2019.127539","volume":"1204","author":"Yusefi","year":"2020","journal-title":"J Mol Struct"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.mseb.2009.01.029","volume":"162","author":"Hessien","year":"2009","journal-title":"Mater Sci Eng B"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1016\/j.carbpol.2011.08.022","volume":"87","author":"Lu","year":"2012","journal-title":"Carbohydr Polym"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"7132","DOI":"10.1021\/ie9001052","volume":"48","author":"Wu","year":"2009","journal-title":"Ind Eng Chem Res"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"1804","DOI":"10.1016\/j.carbpol.2010.10.040","volume":"83","author":"Chen","year":"2011","journal-title":"Carbohydr Polym"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"3941","DOI":"10.1016\/j.biortech.2009.02.028","volume":"100","author":"Basta","year":"2009","journal-title":"Bioresour Technol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"012040","DOI":"10.1088\/1757-899X\/128\/1\/012040","volume":"128","author":"Nandiyanto","year":"2016","journal-title":"IOP Conf Ser Mater Sci Eng"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/j.carbpol.2011.02.022","volume":"85","author":"Chen","year":"2011","journal-title":"Carbohydr Polym"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.carbpol.2013.02.022","volume":"95","author":"Jiang","year":"2013","journal-title":"Carbohydr Polym"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.foodchem.2016.10.048","volume":"221","author":"de Oliveira","year":"2017","journal-title":"Food Chem"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1021\/ja044336a","volume":"127","author":"Hulme","year":"2005","journal-title":"J Am Chem Soc"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"1962","DOI":"10.1021\/jf1020347","volume":"59","author":"Li","year":"2011","journal-title":"J Agric Food Chem"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.carbpol.2017.01.036","volume":"163","author":"Zainuddin","year":"2017","journal-title":"Carbohydr Polym"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.indcrop.2017.05.011","volume":"105","author":"Daneshfozoun","year":"2017","journal-title":"Ind Crops Prod"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"e02404","DOI":"10.1016\/j.heliyon.2019.e02404","volume":"5","author":"Kadry","year":"2019","journal-title":"Heliyon"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1016\/j.carbpol.2017.12.014","volume":"181","author":"Seabra","year":"2018","journal-title":"Carbohydr Polym"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1016\/j.ijpharm.2012.10.022","volume":"441","author":"Zhu","year":"2013","journal-title":"Int J Pharm"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1016\/j.ijpharm.2015.09.044","volume":"495","author":"Illangakoon","year":"2015","journal-title":"Int J Pharm"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1080\/10717544.2019.1582729","volume":"26","author":"Radu","year":"2019","journal-title":"Drug Deliv"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"2021","DOI":"10.2147\/IJN.S124318","volume":"12","author":"Bhandari","year":"2017","journal-title":"Int J Nanomedicine"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.5138\/ijdd.2009.0975.0215.01001","volume":"1","author":"Pragati","year":"2009","journal-title":"J Drug Deliv"},{"key":"ref66","unstructured":"Cancer IAfRo. IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man; 1972:1"},{"key":"ref67","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1089\/ind.2014.0024","volume":"11","author":"Roman","year":"2015","journal-title":"Ind Biotechnol"},{"key":"ref68","first-page":"1512","volume":"35","author":"Watanabe","year":"1989","journal-title":"Gan No Rinsho"},{"key":"ref69","doi-asserted-by":"publisher","volume-title":"Electrospun Materials for Tissue Engineering and Biomedical Applications","year":"2017","DOI":"10.1016\/B978-0-08-101022-8.00013-2"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"1224","DOI":"10.1016\/j.drudis.2017.05.006","volume":"22","author":"Banerjee","year":"2017","journal-title":"Drug Discov Today"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=60126","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=60126","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,28]],"date-time":"2020-07-28T21:48:54Z","timestamp":1595972934000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/the-potential-anticancer-activity-of-5-fluorouracil-loaded-in-cellulos-peer-reviewed-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":70,"URL":"https:\/\/doi.org\/10.2147\/ijn.s250047","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7]]}}}