{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T13:07:42Z","timestamp":1785589662383,"version":"3.56.0"},"reference-count":54,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s299969","type":"journal-article","created":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T21:38:17Z","timestamp":1621892297000},"page":"3565-3578","source":"Crossref","is-referenced-by-count":71,"title":["Mesenchymal Stem Cells Attenuate Renal Fibrosis via Exosomes-Mediated Delivery of microRNA Let-7i-5p Antagomir"],"prefix":"10.2147","volume":"Volume 16","author":[{"given":"Juan","family":"Jin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengmei","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danna","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenfang","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianguang","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2021,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.semcdb.2018.05.024","volume":"91","author":"Chevalier","year":"2019","journal-title":"Semin Cell Dev Biol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.3390\/ijms17081314","volume":"17","author":"Parrish","year":"2016","journal-title":"Int J Mol Sci"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1089\/dis.2006.9.86","volume":"9","author":"Chen","year":"2006","journal-title":"Dis Manag"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"16","DOI":"10.3389\/fmed.2015.00016","volume":"2","author":"Mallipattu","year":"2015","journal-title":"Front Med (Lausanne)"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1016\/j.kint.2018.10.018","volume":"95","author":"Floege","year":"2019","journal-title":"Kidney Int"},{"key":"ref6","first-page":"776","volume":"96","author":"Gaitonde","year":"2017","journal-title":"Am Fam Physician"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1038\/nrneph.2015.85","volume":"11","author":"Wouters","year":"2015","journal-title":"Nat Rev Nephrol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"s03","DOI":"10.1590\/1806-9282.66.s1.3","volume":"66","author":"Ammirati","year":"2020","journal-title":"Rev Assoc Med Bras"},{"key":"ref9","first-page":"9","volume":"27","author":"Hsieh","year":"2018","journal-title":"Acta Neurol Taiwan"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"337","DOI":"10.7326\/0003-4819-127-5-199709010-00001","volume":"127","author":"Giatras","year":"1997","journal-title":"Ann Intern Med"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1046\/j.1523-1755.2000.00840.x","volume":"57","author":"Pereira","year":"2000","journal-title":"Kidney Int"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1152\/physiolgenomics.00039.2017","volume":"50","author":"Lv","year":"2018","journal-title":"Physiol Genomics"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"82","DOI":"10.3389\/fphys.2015.00082","volume":"6","author":"Meng","year":"2015","journal-title":"Front Physiol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1038\/ki.1993.259","volume":"44","author":"Solez","year":"1993","journal-title":"Kidney Int"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1681\/ASN.2009091005","volume":"22","author":"Farris","year":"2011","journal-title":"J Am Soc Nephrol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1111\/nep.13467","volume":"23","author":"Chou","year":"2018","journal-title":"Nephrology (Carlton)"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"43790","DOI":"10.1038\/srep43790","volume":"7","author":"Tu","year":"2017","journal-title":"Sci Rep"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1470320317717831","DOI":"10.1177\/1470320317717831","volume":"18","author":"Xu","year":"2017","journal-title":"J Renin Angiotensin Aldosterone Syst"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1089\/rej.2018.2104","volume":"22","author":"Dou","year":"2019","journal-title":"Rejuvenation Res"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.kint.2016.12.023","volume":"92","author":"Eirin","year":"2017","journal-title":"Kidney Int"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"8387350","DOI":"10.1155\/2019\/8387350","volume":"2019","author":"Zhuang","year":"2019","journal-title":"Stem Cells Int"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1111\/j.1582-4934.2007.00041.x","volume":"11","author":"P\u0103unescu","year":"2007","journal-title":"J Cell Mol Med"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1080\/08860220902928981","volume":"31","author":"Singaravelu","year":"2009","journal-title":"Ren Fail"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/978-1-4939-3584-0_7","volume":"1416","author":"Gnecchi","year":"2016","journal-title":"Methods Mol Biol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"70707","DOI":"10.18632\/oncotarget.19979","volume":"8","author":"Zhu","year":"2017","journal-title":"Oncotarget"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"e346","DOI":"10.1038\/emm.2017.63","volume":"49","author":"Lou","year":"2017","journal-title":"Exp Mol Med"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1038\/s41392-020-00261-0","volume":"5","author":"Dai","year":"2020","journal-title":"Signal Transduct Target Ther"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1186\/s13287-020-01792-7","volume":"11","author":"Wang","year":"2020","journal-title":"Stem Cell Res Ther"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1290","DOI":"10.1038\/mt.2016.90","volume":"24","author":"Wang","year":"2016","journal-title":"Mol Ther"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"11357","DOI":"10.1038\/s41598-019-47778-1","volume":"9","author":"Conserva","year":"2019","journal-title":"Sci Rep"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1681\/ASN.2012080849","volume":"24","author":"Zhou","year":"2013","journal-title":"J Am Soc Nephrol"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1016\/j.ymthe.2019.02.009","volume":"27","author":"Liu","year":"2019","journal-title":"Mol Ther"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"14518","DOI":"10.1073\/pnas.0903458106","volume":"106","author":"Grgic","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref34","first-page":"1","volume":"51","author":"Kim","year":"2019","journal-title":"Exp Mol Med"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"8197","DOI":"10.7150\/thno.43968","volume":"10","author":"Zhou","year":"2020","journal-title":"Theranostics"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"4145","DOI":"10.1038\/s41598-017-04067-z","volume":"7","author":"Li","year":"2017","journal-title":"Sci Rep"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"e0175242","DOI":"10.1371\/journal.pone.0175242","volume":"12","author":"Gooch","year":"2017","journal-title":"PLoS One"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1186\/s13075-019-2044-2","volume":"21","author":"Luan","year":"2019","journal-title":"Arthritis Res Ther"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"9425","DOI":"10.7150\/thno.43315","volume":"10","author":"Chen","year":"2020","journal-title":"Theranostics"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"34842","DOI":"10.1038\/srep34842","volume":"6","author":"Nagaishi","year":"2016","journal-title":"Sci Rep"},{"key":"ref41","first-page":"4998","volume":"12","author":"Liu","year":"2020","journal-title":"Am J Transl Res"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1186\/s13287-020-01852-y","volume":"11","author":"Xiang","year":"2020","journal-title":"Stem Cell Res Ther"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1186\/s13287-018-1069-9","volume":"9","author":"Qiu","year":"2018","journal-title":"Stem Cell Res Ther"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"2963","DOI":"10.1111\/jcmm.13208","volume":"21","author":"Lou","year":"2017","journal-title":"J Cell Mol Med"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1016\/j.ebiom.2018.04.023","volume":"31","author":"Zhou","year":"2018","journal-title":"EBioMedicine"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/s13287-017-0760-6","volume":"9","author":"Liu","year":"2018","journal-title":"Stem Cell Res Ther"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"2898","DOI":"10.1007\/s10620-018-5234-x","volume":"63","author":"Zhang","year":"2018","journal-title":"Dig Dis Sci"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.exer.2018.03.013","volume":"172","author":"Ma","year":"2018","journal-title":"Exp Eye Res"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1007\/s00109-003-0517-9","volume":"82","author":"Zeisberg","year":"2004","journal-title":"J Mol Med (Berl)"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"10539","DOI":"10.2147\/CMAR.S221585","volume":"11","author":"Sun","year":"2019","journal-title":"Cancer Manag Res"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"e1006623","DOI":"10.1371\/journal.pgen.1006623","volume":"13","author":"Jin","year":"2017","journal-title":"PLoS Genet"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"e3000420","DOI":"10.1371\/journal.pbio.3000420","volume":"17","author":"Shi","year":"2019","journal-title":"PLoS Biol"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"6250","DOI":"10.26355\/eurrev_201907_18445","volume":"23","author":"Shao","year":"2019","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"1555","DOI":"10.1038\/s41401-019-0244-6","volume":"40","author":"Lu","year":"2019","journal-title":"Acta Pharmacol Sin"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=69775","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=69775","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T21:38:23Z","timestamp":1621892303000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/mesenchymal-stem-cells-attenuate-renal-fibrosis-via-exosomes-mediated--peer-reviewed-fulltext-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":54,"URL":"https:\/\/doi.org\/10.2147\/ijn.s299969","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5]]}}}