{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:26:38Z","timestamp":1790785598713,"version":"4.1.0"},"reference-count":49,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s361377","type":"journal-article","created":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T00:30:22Z","timestamp":1656289822000},"page":"2791-2804","source":"Crossref","is-referenced-by-count":22,"title":["Perampanel Reduces Brain Damage via Induction of M2 Microglia in a Neonatal Rat Stroke Model"],"prefix":"10.2147","volume":"Volume 17","author":[{"given":"Hyo Jung","family":"Shin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ka Young","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joon Won","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Gyu","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7691-1394","authenticated-orcid":true,"given":"Dong Woon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0725-4025","authenticated-orcid":true,"given":"Yoon Young","family":"Yi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2022,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/S1474-4422(04)00679-9","volume":"3","author":"Nelson","year":"2004","journal-title":"Lancet Neurol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1038\/jcbfm.2014.41","volume":"34","author":"Fernandez-Lopez","year":"2014","journal-title":"J Cereb Blood Flow Metab"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"71","DOI":"10.5469\/neuroint.2019.00164","volume":"14","author":"Ko","year":"2019","journal-title":"Neurointervention"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"146","DOI":"10.3174\/ajnr.A3169","volume":"34","author":"Murphy","year":"2013","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"e51","DOI":"10.1161\/STR.0000000000000183","volume":"50","author":"Ferriero","year":"2019","journal-title":"Stroke"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"2006","DOI":"10.3892\/mmr.2020.11003","volume":"21","author":"Jiang","year":"2020","journal-title":"Mol Med Rep"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1111\/cns.12575","volume":"22","author":"Meng","year":"2016","journal-title":"CNS Neurosci Ther"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"6295","DOI":"10.1039\/D1BM00486G","volume":"9","author":"Kim","year":"2021","journal-title":"Biomater Sci-UK"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1515\/ntrev-2012-0084","volume":"2","author":"Li","year":"2013","journal-title":"Nanotechnol Rev"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"443","DOI":"10.3390\/polym12020443","volume":"12","author":"Shin","year":"2020","journal-title":"Polymers-Basel"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1607","DOI":"10.2217\/nnm-2018-0054","volume":"13","author":"Shin","year":"2018","journal-title":"Nanomedicine-UK"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.3390\/polym12051014","volume":"12","author":"Shin","year":"2020","journal-title":"Polymers-Basel"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"27","DOI":"10.30827\/ars.v57i1.4384","volume":"57","author":"Garcia-Corvillo","year":"2016","journal-title":"Ars Pharm"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"5657","DOI":"10.3390\/ijms22115657","volume":"22","author":"Lee","year":"2021","journal-title":"Int J Mol Sci"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1113","DOI":"10.2217\/nnm-2019-0462","volume":"15","author":"Pham","year":"2020","journal-title":"Nanomedicine-UK"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1111\/j.1528-1167.2011.03109.x","volume":"52","author":"Hanada","year":"2011","journal-title":"Epilepsia"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1408","DOI":"10.1212\/WNL.0b013e318254473a","volume":"78","author":"Krauss","year":"2012","journal-title":"Neurology"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1111\/j.1528-1167.2012.03638.x","volume":"54","author":"French","year":"2013","journal-title":"Epilepsia"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/j.neuroscience.2018.06.043","volume":"386","author":"Nakajima","year":"2018","journal-title":"Neuroscience"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1007\/s10571-017-0489-x","volume":"38","author":"Niu","year":"2018","journal-title":"Cell Mol Neurobiol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1007\/s10571-016-0341-8","volume":"37","author":"Chen","year":"2017","journal-title":"Cell Mol Neurobiol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"2450","DOI":"10.3390\/ijms20102450","volume":"20","author":"Ceprian","year":"2019","journal-title":"Int J Mol Sci"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"3703","DOI":"10.3390\/ijms21103703","volume":"21","author":"Yi","year":"2020","journal-title":"Int J Mol Sci"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"3107","DOI":"10.2147\/IJN.S63535","volume":"9","author":"Maji","year":"2014","journal-title":"Int J Nanomedicine"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1449","DOI":"10.1097\/00001756-200105250-00030","volume":"12","author":"Kang","year":"2001","journal-title":"Neuroreport"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/0165-5728(90)90073-V","volume":"27","author":"Blasi","year":"1990","journal-title":"J Neuroimmunol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1007\/s12975-020-00874-1","volume":"12","author":"Hwang","year":"2021","journal-title":"Transl Stroke Res"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1523\/JNEUROSCI.20-01-00251.2000","volume":"20","author":"Noda","year":"2000","journal-title":"J Neurosci"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"141","DOI":"10.4110\/in.2013.13.4.141","volume":"13","author":"Kim","year":"2013","journal-title":"Immune Netw"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"8978704","DOI":"10.1155\/2020\/8978704","volume":"2020","author":"Peng","year":"2020","journal-title":"Biomed Res Int"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"136","DOI":"10.3978\/j.issn.2305-5839.2015.03.49","volume":"3","author":"Wang","year":"2015","journal-title":"Ann Transl Med"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1265","DOI":"10.1517\/17425255.4.10.1265","volume":"4","author":"Harry","year":"2008","journal-title":"Expert Opin Drug Metab Toxicol"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1007\/BF00218471","volume":"223","author":"Murabe","year":"1982","journal-title":"Cell Tissue Res"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1002\/(SICI)1098-1063(1998)8:5<458::AID-HIPO6>3.0.CO;2-N","volume":"8","author":"Dalmau","year":"1998","journal-title":"Hippocampus"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"4216","DOI":"10.1523\/JNEUROSCI.3441-12.2013","volume":"33","author":"Cunningham","year":"2013","journal-title":"J Neurosci"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.neuroscience.2018.01.023","volume":"405","author":"Mallard","year":"2019","journal-title":"Neuroscience"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"1456","DOI":"10.1126\/science.1202529","volume":"333","author":"Paolicelli","year":"2011","journal-title":"Science"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1002\/btm2.10175","volume":"5","author":"Joseph","year":"2020","journal-title":"Bioeng Transl Med"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"101121","DOI":"10.1016\/j.redox.2019.101121","volume":"21","author":"Peng","year":"2019","journal-title":"Redox Biol"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41419-017-0012-9","volume":"9","author":"Wang","year":"2018","journal-title":"Cell Death Dis"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"1181","DOI":"10.1007\/s12035-014-9070-5","volume":"53","author":"Tang","year":"2016","journal-title":"Mol Neurobiol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1097\/00004647-199703000-00006","volume":"17","author":"Gottlieb","year":"1997","journal-title":"J Cerebr Blood F Met"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"104848","DOI":"10.1016\/j.nbd.2020.104848","volume":"140","author":"Mazzocchetti","year":"2020","journal-title":"Neurobiol Dis"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.01236","volume":"10","author":"Collmann","year":"2019","journal-title":"Front Immunol"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.yexmp.2008.12.004","volume":"86","author":"Singh","year":"2009","journal-title":"Exp Mol Pathol"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"2790","DOI":"10.1016\/j.biomaterials.2009.01.057","volume":"30","author":"Cartiera","year":"2009","journal-title":"Biomaterials"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"2854","DOI":"10.1016\/j.bioactmat.2021.01.023","volume":"6","author":"Tian","year":"2021","journal-title":"Bioact Mater"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1038\/s41377-020-0319-7","volume":"9","author":"Azzam","year":"2020","journal-title":"Light Sci Appl"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1021\/acs.chemrev.1c00165","volume":"122","author":"Xie","year":"2022","journal-title":"Chem Rev"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=81736","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=81736","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T11:56:56Z","timestamp":1675943816000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/perampanel-reduces-brain-damage-via-induction-of-m2-microglia-in-a-neo-peer-reviewed-fulltext-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":49,"URL":"https:\/\/doi.org\/10.2147\/ijn.s361377","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6]]}}}