{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T01:52:30Z","timestamp":1789091550870,"version":"build-2803163510"},"reference-count":28,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s390866","type":"journal-article","created":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T23:20:06Z","timestamp":1672183206000},"page":"6675-6686","source":"Crossref","is-referenced-by-count":14,"title":["Microfluidic Post-Insertion Method for the Efficient Preparation of PEGylated Liposomes Using High Functionality and Quality Lipids"],"prefix":"10.2147","volume":"Volume 17","author":[{"given":"Yuri","family":"Sugimoto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadaharu","family":"Suga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8233-5426","authenticated-orcid":true,"given":"Naoya","family":"Kato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mizuki","family":"Umino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asako","family":"Yamayoshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0749-8783","authenticated-orcid":true,"given":"Hidefumi","family":"Mukai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8765-2463","authenticated-orcid":true,"given":"Shigeru","family":"Kawakami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2022,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1336","DOI":"10.7150\/thno.15464","volume":"6","author":"Xing","year":"2016","journal-title":"Theranostics"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.jconrel.2012.03.020","volume":"160","author":"Barenholz","year":"2012","journal-title":"J Control Release"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1021\/acsmedchemlett.0c00075","volume":"11","author":"Sanna","year":"2020","journal-title":"ACS Med Chem Lett"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"542","DOI":"10.3390\/pharmaceutics5040542","volume":"5","author":"Nag","year":"2013","journal-title":"Pharmaceutics"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/j.ijpharm.2017.02.041","volume":"521","author":"Suga","year":"2017","journal-title":"Int J Pharm"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"4481","DOI":"10.1021\/acs.molpharmaceut.8b00476","volume":"15","author":"Suga","year":"2018","journal-title":"Mol Pharm"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.ejps.2018.07.036","volume":"123","author":"Hagimori","year":"2018","journal-title":"Eur J Pharm Sci"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1016\/j.jddst.2018.12.037","volume":"49","author":"Suga","year":"2019","journal-title":"J Drug Deliv Sci Technol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"106239","DOI":"10.1016\/j.ejps.2022.106239","volume":"176","author":"Kato","year":"2022","journal-title":"Eur J Pharm Sci"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1983","DOI":"10.1248\/bpb.b16-00462","volume":"39","author":"Lee","year":"2016","journal-title":"Biol Pharm Bull"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1016\/j.ijpharm.2018.10.028","volume":"552","author":"Mare","year":"2018","journal-title":"Int. J. Pharm"},{"key":"ref12","unstructured":"Renee Hood, Donald Lad DeVoe, inventor; University of Maryland, College Park, assignee. Microfluidic Liposome Synthesis, Purification And Active Drug Loading. United States patent US 2017\/0181972 A1. 2017."},{"key":"ref13","doi-asserted-by":"publisher","first-page":"e37","DOI":"10.1038\/mtna.2012.28","volume":"1","author":"Belliveau","year":"2012","journal-title":"Mol Ther Nucleic Acids"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1126\/science.1066238","volume":"295","author":"Stroock","year":"2002","journal-title":"Science"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1601","DOI":"10.4155\/fmc.12.75","volume":"4","author":"Roxin","year":"2012","journal-title":"Future Med Chem"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"20233","DOI":"10.1016\/S0021-9258(17)31981-6","volume":"269","author":"Pfaff","year":"1994","journal-title":"J Biol Chem"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"2801","DOI":"10.1016\/j.bbamem.2012.06.019","volume":"1818","author":"Nakamura","year":"2012","journal-title":"Biochim Biophys Acta"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"320","DOI":"10.3390\/pharmaceutics7030320","volume":"7","author":"Hada","year":"2015","journal-title":"Pharmaceutics"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1248\/bpb.b13-00291","volume":"36","author":"Takafuji","year":"2013","journal-title":"Biol Pharm Bull"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.jconrel.2016.01.009","volume":"224","author":"Kooijmans","year":"2016","journal-title":"J Control Release"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/0014-5793(96)00452-8","volume":"386","author":"Uster","year":"1996","journal-title":"FEBS Lett"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"100450","DOI":"10.1016\/j.dmpk.2022.100450","volume":"44","author":"Mukai","year":"2022","journal-title":"Drug Metab Pharmacokinet"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1056\/NEJMoa1716153","volume":"379","author":"Adams","year":"2018","journal-title":"N Engl J Med"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"7300","DOI":"10.1021\/acs.nanolett.5b02497","volume":"15","author":"Kauffman","year":"2015","journal-title":"Nano Lett"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.1016\/j.nano.2016.12.014","volume":"13","author":"Kulkarni","year":"2017","journal-title":"Nanomedicine"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1038\/nbt.1807","volume":"29","author":"Alvarez-Erviti","year":"2011","journal-title":"Nat Biotechnol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jconrel.2019.12.005","volume":"318","author":"Zhao","year":"2020","journal-title":"J Control Release"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"10817","DOI":"10.1021\/acsnano.8b02587","volume":"12","author":"Jc Bose","year":"2018","journal-title":"ACS Nano"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=86424","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=86424","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T23:20:09Z","timestamp":1672183209000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/microfluidic-post-insertion-method-for-the-efficient-preparation-of-pe-peer-reviewed-fulltext-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":28,"URL":"https:\/\/doi.org\/10.2147\/ijn.s390866","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12]]}}}