{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T18:19:52Z","timestamp":1788200392243,"version":"build-2803163510"},"reference-count":53,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s416966","type":"journal-article","created":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T10:35:07Z","timestamp":1689590107000},"page":"3879-3896","source":"Crossref","is-referenced-by-count":15,"title":["Proteinase K\/Retinoic Acid-Loaded Cationic Liposomes as Multifunctional Anti-Acne Therapy to Disorganize Biofilm and Regulate Keratinocyte Proliferation"],"prefix":"10.2147","volume":"Volume 18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0338-3639","authenticated-orcid":true,"given":"Ming-Jun","family":"Tsai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Yu","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji\u0159\u00ed","family":"Trousil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Calvin T","family":"Sung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Hua","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2114-7709","authenticated-orcid":true,"given":"Jia-You","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Chun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"e13279","DOI":"10.1111\/dth.13279","volume":"33","author":"Goodarzi","year":"2020","journal-title":"Dermatol Ther"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"128","DOI":"10.3390\/microorganisms7050128","volume":"7","author":"McLaughlin","year":"2019","journal-title":"Microorganisms"},{"key":"ref3","doi-asserted-by":"crossref","DOI":"10.1111\/bjd.19477","volume":"184","author":"Layton","year":"2021","journal-title":"Br J Dermatol"},{"key":"ref4","doi-asserted-by":"crossref","DOI":"10.1038\/jid.2010.281","volume":"131","author":"Isard","year":"2011","journal-title":"J Invest Dermatol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"168","DOI":"10.3390\/jcm9010168","volume":"9","author":"Park","year":"2020","journal-title":"J Clin Med"},{"key":"ref6","volume":"32","author":"Dr\u00e9no","year":"2018","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref7","doi-asserted-by":"crossref","DOI":"10.1111\/j.1365-2133.2012.10897.x","volume":"167","author":"Jahns","year":"2012","journal-title":"Br J Dermatol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"21104","DOI":"10.1038\/s41598-022-25436-3","volume":"12","author":"Cavallo","year":"2022","journal-title":"Sci Rep"},{"key":"ref9","volume":"131","author":"Wang","year":"2021","journal-title":"J Appl Microbiol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"6392","DOI":"10.3390\/molecules26216392","volume":"26","author":"Lin","year":"2021","journal-title":"Molecules"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2018.09.005","volume":"308","author":"Kuehnast","year":"2018","journal-title":"Int J Med Microbiol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"6156720","DOI":"10.1155\/2020\/6156720","volume":"2020","author":"Eladawy","year":"2020","journal-title":"Interdiscip Perspect Infect Dis"},{"key":"ref13","doi-asserted-by":"crossref","DOI":"10.1016\/S0022-2275(20)33392-7","volume":"40","author":"Campanh\u00e3","year":"1999","journal-title":"J Lipid Res"},{"key":"ref14","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejpb.2020.01.013","volume":"149","author":"Montefusco-Pereira","year":"2020","journal-title":"Eur J Pharm Biopharm"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.3389\/fmicb.2018.01493","volume":"9","author":"Alalaiwe","year":"2018","journal-title":"Front Microbiol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"8121","DOI":"10.2147\/IJN.S335804","volume":"16","author":"Fang","year":"2021","journal-title":"Int J Nanomed"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s13555-017-0185-2","volume":"7","author":"Leyden","year":"2017","journal-title":"Dermatol Ther"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"3703","DOI":"10.2174\/0929867325666180313110917","volume":"25","author":"Raminelli","year":"2018","journal-title":"Curr Med Chem"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"5351","DOI":"10.1007\/s12325-022-02319-7","volume":"39","author":"Milosheska","year":"2022","journal-title":"Adv Ther"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.addr.2020.06.022","volume":"156","author":"Filipczak","year":"2020","journal-title":"Adv Drug Deliv Rev"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"122162","DOI":"10.1016\/j.ijpharm.2022.122162","volume":"627","author":"Lee","year":"2022","journal-title":"Int J Pharm"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"165","DOI":"10.3934\/microbiol.2018.1.165","volume":"4","author":"Polyudova","year":"2018","journal-title":"AIMS Microbiol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3390\/molecules21010015","volume":"21","author":"Tsai","year":"2016","journal-title":"Molecules"},{"key":"ref24","first-page":"e56825","volume":"133","author":"Cappiello","year":"2018","journal-title":"J Vis Exp"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1128\/CMR.00092-13","volume":"27","author":"Achermann","year":"2014","journal-title":"Clin Microbiol Rev"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1080\/14740338.2020.1757646","volume":"19","author":"Otlewska","year":"2020","journal-title":"Expert Opin Drug Saf"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"138","DOI":"10.3390\/pharmaceutics13020138","volume":"13","author":"Salem","year":"2021","journal-title":"Pharmaceutics"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1080\/08982104.2019.1630646","volume":"30","author":"Ero\u01e7lu","year":"2020","journal-title":"J Liposome Res"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1080\/10717544.2018.1492046","volume":"25","author":"Veloso","year":"2018","journal-title":"Drug Deliv"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1038\/s41598-020-79976-7","volume":"11","author":"Kannan","year":"2021","journal-title":"Sci Rep"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"7646","DOI":"10.1021\/la300948n","volume":"28","author":"Botequim","year":"2012","journal-title":"Langmuir"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.anaerobe.2016.10.001","volume":"42","author":"Jahns","year":"2016","journal-title":"Anaerobe"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1021\/acsinfecdis.7b00170","volume":"4","author":"Wolfmeier","year":"2018","journal-title":"ACS Infect Dis"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/ja.2012.98","volume":"66","author":"Shukla","year":"2013","journal-title":"J Antibiot"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.ijfoodmicro.2014.06.025","volume":"187","author":"Nguyen","year":"2014","journal-title":"Int J Food Microbiol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1111\/1751-7915.13949","volume":"15","author":"Zerillo","year":"2022","journal-title":"Microb Biotechnol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1186\/s12951-021-00851-2","volume":"19","author":"Barros","year":"2021","journal-title":"J Nanobiotechnol"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1039\/D0CS00986E","volume":"50","author":"Blackman","year":"2021","journal-title":"Chem Soc Rev"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/s42003-020-01266-9","volume":"3","author":"Cho","year":"2020","journal-title":"Commun Biol"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/ja.2016.138","volume":"70","author":"Culp","year":"2017","journal-title":"J Antibiot"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/s10753-019-01125-8","volume":"43","author":"Zhu","year":"2020","journal-title":"Inflammation"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.3390\/pharmaceutics14091952","volume":"14","author":"Dell\u2019Annunziata","year":"2022","journal-title":"Pharmaceutics"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"392","DOI":"10.5114\/ada.2019.87443","volume":"4","author":"Zasada","year":"2019","journal-title":"Adv Dermatol Allergol"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1186\/s11671-018-2728-6","volume":"13","author":"Forroozandeh","year":"2018","journal-title":"Nanoscale Res Lett"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1007\/s11095-021-03079-9","volume":"38","author":"Liu","year":"2021","journal-title":"Pharm Res"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.jconrel.2022.09.025","volume":"351","author":"Phatale","year":"2022","journal-title":"J Control Release"},{"key":"ref47","first-page":"3501","volume":"15","author":"Yoshioka","year":"2018","journal-title":"Exp Ther Med"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"119500","DOI":"10.1016\/j.ijpharm.2020.119500","volume":"585","author":"Zhang","year":"2020","journal-title":"Int J Pharm"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"646554","DOI":"10.3389\/fbioe.2021.646554","volume":"9","author":"Yu","year":"2021","journal-title":"Front Bioeng Biotechnol"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"100063","DOI":"10.1016\/j.bioflm.2021.100063","volume":"4","author":"Coenye","year":"2022","journal-title":"Biofilm"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"12304","DOI":"10.3390\/ijms222212304","volume":"22","author":"Kim","year":"2021","journal-title":"Int J Mol Sci"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1001\/jama.2021.17633","volume":"326","author":"Eichenfield","year":"2021","journal-title":"JAMA"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/jocd.12193","volume":"15","author":"Kong","year":"2015","journal-title":"J Cosmet Dermatol"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=91236","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=91236","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T10:35:27Z","timestamp":1689590127000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/proteinase-kretinoic-acid-loaded-cationic-liposomes-as-multifunctional-peer-reviewed-fulltext-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":53,"URL":"https:\/\/doi.org\/10.2147\/ijn.s416966","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7]]}}}