{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:14:10Z","timestamp":1792188850117,"version":"4.4.0"},"reference-count":52,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s433510","type":"journal-article","created":{"date-parts":[[2023,11,28]],"date-time":"2023-11-28T07:10:12Z","timestamp":1701155412000},"page":"7047-7063","source":"Crossref","is-referenced-by-count":31,"title":["Exosome Derived from Mesenchymal Stem Cells Alleviates Hypertrophic Scar by Inhibiting the Fibroblasts via TNFSF-13\/HSPG2 Signaling Pathway"],"prefix":"10.2147","volume":"Volume 18","author":[{"given":"Huimin","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengyu","family":"Zang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9127-6309","authenticated-orcid":true,"given":"Wen","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linfeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhang","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongtao","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1016\/j.cps.2017.05.024","volume":"44","author":"Diegidio","year":"2017","journal-title":"Clin Plast Surg"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1111\/iwj.12944","volume":"15","author":"Matiasek","year":"2018","journal-title":"Int Wound J"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"7601","DOI":"10.1021\/acsnano.7b07439","volume":"12","author":"Weng","year":"2018","journal-title":"ACS nano"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"4586569","DOI":"10.1155\/2022\/4586569","volume":"2022","author":"Qian","year":"2022","journal-title":"Oxid Med Cell Longev"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1111\/iwj.12283","volume":"13","author":"Chun","year":"2016","journal-title":"Int Wound J"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1016\/S0140-6736(16)31406-4","volume":"388","author":"Finnerty","year":"2016","journal-title":"Lancet"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"117174","DOI":"10.1016\/j.lfs.2019.117174","volume":"241","author":"Song","year":"2020","journal-title":"Life Sci"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"105236","DOI":"10.1016\/j.isci.2022.105236","volume":"25","author":"Zhang","year":"2022","journal-title":"iScience"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1016\/j.fsc.2019.07.013","volume":"27","author":"Lee Peng","year":"2019","journal-title":"Facial Plast Surg Clin North Am"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.bjps.2018.05.052","volume":"72","author":"Hietanen","year":"2019","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"13670","DOI":"10.1038\/s41598-021-93203-x","volume":"11","author":"Chen","year":"2021","journal-title":"Sci Rep"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1272\/jnms.JNMS.2021_88-106","volume":"88","author":"Ogawa","year":"2021","journal-title":"J Nippon Med Schl"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"e2201989","DOI":"10.1002\/adhm.202201989","volume":"12","author":"Yao","year":"2023","journal-title":"Adv Healthcare Mater"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"39","DOI":"10.3389\/fvets.2017.00039","volume":"4","author":"Casado","year":"2017","journal-title":"Front Vet Sci"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"102007","DOI":"10.1016\/j.tice.2022.102007","volume":"80","author":"Khazaei","year":"2023","journal-title":"Tissue Cell"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"17802","DOI":"10.1021\/acsnano.2c08774","volume":"16","author":"Tenchov","year":"2022","journal-title":"ACS nano"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"102102","DOI":"10.1016\/j.tice.2023.102102","volume":"82","author":"Rahmati","year":"2023","journal-title":"Tissue Cell"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1016\/j.cca.2019.10.022","volume":"500","author":"Chung","year":"2020","journal-title":"Clinica Chimica Acta"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.actbio.2018.12.045","volume":"86","author":"Liao","year":"2019","journal-title":"Acta Biomater"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"32993","DOI":"10.1038\/srep32993","volume":"6","author":"Hu","year":"2016","journal-title":"Sci Rep"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"e2202751","DOI":"10.1002\/adhm.202202751","volume":"12","author":"Zhang","year":"2023","journal-title":"Adv Healthcare Mater"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1900513","DOI":"10.1002\/advs.201900513","volume":"6","author":"Kim","year":"2019","journal-title":"Adv Sci"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"124","DOI":"10.7507\/1002-1892.201903058","volume":"34","author":"Wang","year":"2020","journal-title":"Zhongguo xiu fu chong jian wai ke za zhi\u300a\u4e2d\u56fd\u4fee\u590d\u91cd\u5efa\u5916\u79d1\u6742\u5fd7\u300b"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1152\/physrev.00045.2017","volume":"99","author":"Dostert","year":"2019","journal-title":"Physiol Rev"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1186\/s12974-016-0552-4","volume":"13","author":"Funk","year":"2016","journal-title":"J Neuroinflam"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"22939","DOI":"10.1016\/S0021-9258(18)54445-8","volume":"266","author":"Noonan","year":"1991","journal-title":"J Biol Chem"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1652","DOI":"10.1074\/jbc.M115.686295","volume":"291","author":"Purushothaman","year":"2016","journal-title":"J Biol Chem"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"e0151736","DOI":"10.1371\/journal.pone.0151736","volume":"11","author":"Baiocchini","year":"2016","journal-title":"PLoS One"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1322","DOI":"10.1002\/jcb.24788","volume":"115","author":"Warren","year":"2014","journal-title":"J Cell Biochem"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1007\/s10735-016-9677-0","volume":"47","author":"Shu","year":"2016","journal-title":"J Mol Histol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1038\/s41586-021-03818-3","volume":"597","author":"Tsiantoulas","year":"2021","journal-title":"Nature"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"4023","DOI":"10.2147\/IJN.S377317","volume":"17","author":"Zhao","year":"2022","journal-title":"Int J Nanomedicine"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1111\/phpp.12716","volume":"38","author":"Yan","year":"2022","journal-title":"Photodermatol Photoimmunol Photomed"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"750","DOI":"10.1111\/1523-1747.ep12606979","volume":"104","author":"Zhang","year":"1995","journal-title":"J Invest Dermatol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"606","DOI":"10.3390\/ijms18030606","volume":"18","author":"Ogawa","year":"2017","journal-title":"Int J Mol Sci"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/s41038-019-0175-y","volume":"7","author":"Ogawa","year":"2019","journal-title":"Burns Trauma"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"1219907","DOI":"10.3389\/fimmu.2023.1219907","volume":"14","author":"Steele","year":"2023","journal-title":"Front Immunol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1309\/AJCP4JP8BZOMHEAW","volume":"141","author":"Qian","year":"2014","journal-title":"Am J Clin Pathol"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"4699","DOI":"10.1158\/0008-5472.CAN-04-0810","volume":"64","author":"Zhou","year":"2004","journal-title":"Cancer Res"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"1699","DOI":"10.1016\/S0002-9440(10)61252-7","volume":"167","author":"Chen","year":"2005","journal-title":"Am J Pathol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1111\/j.0105-2896.2006.00375.x","volume":"210","author":"Hoffmann","year":"2006","journal-title":"Immunol Rev"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1146\/annurev.immunol.021908.132641","volume":"27","author":"Vallabhapurapu","year":"2009","journal-title":"Annu Rev Immunol"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1016\/j.cyto.2012.10.018","volume":"61","author":"Park","year":"2013","journal-title":"Cytokine"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"926","DOI":"10.4049\/jimmunol.2100623","volume":"209","author":"Stephenson","year":"2022","journal-title":"J Immunol"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"107982","DOI":"10.1016\/j.celrep.2020.107982","volume":"32","author":"Cornelis","year":"2020","journal-title":"Cell Rep"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1038\/ni.1699","volume":"10","author":"Hao","year":"2009","journal-title":"Nature Immunol"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"1047907","DOI":"10.3389\/fonc.2022.1047907","volume":"12","author":"Zhang","year":"2022","journal-title":"Front Oncol"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"2408","DOI":"10.1016\/j.neurobiolaging.2013.03.029","volume":"34","author":"Kim","year":"2013","journal-title":"Neurobiol Aging"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"2424","DOI":"10.1111\/iwj.14081","volume":"20","author":"Yuan","year":"2023","journal-title":"Int Wound J"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"658","DOI":"10.22074\/cellj.2021.7595","volume":"23","author":"Rezakhani","year":"2021","journal-title":"Cell J"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"1009338","DOI":"10.3389\/fgene.2022.1009338","volume":"13","author":"Rashidi","year":"2022","journal-title":"Front Genetics"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"9742765","DOI":"10.1155\/2019\/9742765","volume":"2019","author":"Ding","year":"2019","journal-title":"Biomed Res Int"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=94721","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=94721","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,28]],"date-time":"2023-11-28T07:10:18Z","timestamp":1701155418000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/exosome-derived-from-mesenchymal-stem-cells-alleviates-hypertrophic-sc-peer-reviewed-fulltext-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":52,"URL":"https:\/\/doi.org\/10.2147\/ijn.s433510","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11]]}}}