{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T07:10:44Z","timestamp":1783667444110,"version":"3.55.0"},"reference-count":38,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s438742","type":"journal-article","created":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T01:40:05Z","timestamp":1703814005000},"page":"8131-8141","source":"Crossref","is-referenced-by-count":8,"title":["Combination of Chlorambucil and Mercaptopurine Show Effective Anti-Cancer Effects in Mice Model"],"prefix":"10.2147","volume":"Volume 18","author":[{"given":"Weibing","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxin","family":"Di","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengjing","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zixuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haitao","family":"Long","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lumei","family":"Pu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Runtian","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8488-9833","authenticated-orcid":true,"given":"Yanwei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.addr.2015.10.022","volume":"98","author":"Hu","year":"2016","journal-title":"Adv Drug Deliv Rev"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"9518","DOI":"10.1021\/nn405674m","volume":"7","author":"Ma","year":"2013","journal-title":"ACS Nano"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/j.jconrel.2016.06.012","volume":"240","author":"Zhang","year":"2016","journal-title":"J Control Release"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"915","DOI":"10.1016\/j.trecan.2022.06.009","volume":"8","author":"Pomeroy","year":"2022","journal-title":"Trends Cancer"},{"key":"ref5","first-page":"364985","volume":"2011","author":"Woodcock","year":"2011","journal-title":"N Engl J Med"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"5896","DOI":"10.1021\/ja502011g","volume":"136","author":"Liao","year":"2014","journal-title":"J Am Chem Soc"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1038\/s41565-022-01310-1","volume":"18","author":"Detappe","year":"2023","journal-title":"Nat Nanotechnol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"2352","DOI":"10.1111\/cas.15364","volume":"113","author":"Funasaki","year":"2022","journal-title":"Cancer Sci"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"28","DOI":"10.3390\/ijms231810471","volume":"23","author":"Aputen","year":"2022","journal-title":"Int J Mol Sci"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.molliq.2022.120575","volume":"367","author":"Akdogan","year":"2022","journal-title":"J Mol Liq"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"14","DOI":"10.3390\/pharmaceutics15020649","volume":"15","author":"Kumari","year":"2023","journal-title":"Pharmaceutics"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"79","DOI":"10.2147\/IJN.S394819","volume":"18","author":"Zou","year":"2023","journal-title":"Int J Nanomed"},{"key":"ref13","first-page":"12","volume":"23","author":"de Beaumais","year":"2022","journal-title":"Int J Mol Sci"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"4544","DOI":"10.1007\/s12274-021-4037-0","volume":"15","author":"Wang","year":"2022","journal-title":"Nano Res"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/s12951-018-0362-1","volume":"16","author":"Kalimuthu","year":"2018","journal-title":"J Nanobiotechnol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.2147\/IJN.S290466","volume":"16","author":"Zou","year":"2021","journal-title":"Int J Nanomed"},{"key":"ref17","first-page":"2327","volume":"80","author":"Ali","year":"2023","journal-title":"Drug Des Dev Ther"},{"key":"ref18","first-page":"36","volume":"34","author":"Zhang","year":"2022","journal-title":"Adv Mater"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"6937","DOI":"10.2147\/IJN.S332920","volume":"16","author":"Salim","year":"2021","journal-title":"Int J Nanomed"},{"key":"ref20","first-page":"108802","volume":"191","author":"Monajati","year":"2023","journal-title":"Colloids Surf B Biointerfaces"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"1534","DOI":"10.3390\/pharmaceutics14081534","volume":"14","author":"Yi","year":"2022","journal-title":"Pharmaceutics"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"9931","DOI":"10.1039\/D1NJ05974B","volume":"46","author":"Monajati","year":"2022","journal-title":"New J Chem"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"18544","DOI":"10.1039\/D1NJ03134A","volume":"45","author":"Li","year":"2021","journal-title":"New J Chem"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"4983","DOI":"10.1039\/C7PY00196G","volume":"8","author":"Alfurhood","year":"2017","journal-title":"Poly Chem"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.1002\/marc.201600146","volume":"37","author":"Saha","year":"2016","journal-title":"Macromol Rapid Comm"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"12215","DOI":"10.1039\/C9NJ02582K","volume":"43","author":"Xu","year":"2019","journal-title":"New J Chem"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.1007\/s12043-008-0183-0","volume":"71","author":"Gunasekaran","year":"2008","journal-title":"Pramana"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"439","DOI":"10.3390\/md16110439","volume":"16","author":"Wei","year":"2018","journal-title":"Mar Drugs"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"5091","DOI":"10.1002\/pola.26941","volume":"51","author":"Ebbesen","year":"2013","journal-title":"J Polym Sci Pol Chem"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"1967","DOI":"10.1021\/bc4002932","volume":"24","author":"Dhal","year":"2013","journal-title":"Bioconjugate Chem"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"2347","DOI":"10.1021\/bm060336m","volume":"7","author":"Callahan","year":"2006","journal-title":"Biomacromolecules"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.ijpharm.2020.119173","volume":"579","author":"Rani","year":"2020","journal-title":"Int J Pharm"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"881","DOI":"10.2147\/IJN.S393507","volume":"18","author":"Wang","year":"2023","journal-title":"Int J Nanomed"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.ijpharm.2017.02.008","volume":"520","author":"Ghorbani","year":"2017","journal-title":"Int J Pharm"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"w739","DOI":"10.1093\/nar\/gkac382","volume":"50","author":"Ianevski","year":"2022","journal-title":"Nucleic Acids Res"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"646","DOI":"10.3390\/nano12040646","volume":"12","author":"Xin","year":"2022","journal-title":"Nanomaterials"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"113062","DOI":"10.1016\/j.biopha.2022.113062","volume":"150","author":"Rodr\u00edguez-Exp\u00f3sito","year":"2022","journal-title":"Biomed Pharmacother"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/j.actbio.2018.11.050","volume":"84","author":"Chen","year":"2019","journal-title":"Acta Biomater"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=95652","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=95652","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T01:40:29Z","timestamp":1703814029000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/combination-of-chlorambucil-and-mercaptopurine-show-effective-anti-can-peer-reviewed-fulltext-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":38,"URL":"https:\/\/doi.org\/10.2147\/ijn.s438742","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12]]}}}