{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T04:15:48Z","timestamp":1790655348900,"version":"4.1.0"},"reference-count":53,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s474098","type":"journal-article","created":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T11:05:13Z","timestamp":1730372713000},"page":"11055-11070","source":"Crossref","is-referenced-by-count":20,"title":["TME-Activated MnO2\/Pt Nanoplatform of Hydroxyl Radical and Oxygen Generation to Synergistically Promote Radiotherapy and MR Imaging of Glioblastoma"],"prefix":"10.2147","volume":"Volume 19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6761-1338","authenticated-orcid":true,"given":"Lijuan","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingbo","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunjuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaqiong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Jiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiyun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2024,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"5687","DOI":"10.1038\/s41467-020-19225-7","volume":"11","author":"Gregory","year":"2020","journal-title":"Nat Commun"},{"key":"ref2","volume-title":"Malignant Brain Tumors: State-of-The-Art Treatment","year":"2016"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"100988","DOI":"10.1016\/j.nantod.2020.100988","volume":"35","author":"Lv","year":"2020","journal-title":"Nano Today"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1176","DOI":"10.3390\/cancers14051176","volume":"14","author":"Park","year":"2022","journal-title":"Cancers"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"126305","DOI":"10.1016\/j.cej.2020.126305","volume":"403","author":"Liu","year":"2021","journal-title":"Chem Eng J"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"22537","DOI":"10.1002\/anie.202003653","volume":"59","author":"Li","year":"2020","journal-title":"Angew Chem Int Ed"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1039\/d1bm01401c","volume":"10","author":"Li","year":"2022","journal-title":"Biomater Sci"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1700996","DOI":"10.1002\/adma.201700996","volume":"29","author":"Song","year":"2017","journal-title":"Adv Mater"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1200\/JCO.2004.00.1768","volume":"24","author":"Suh","year":"2006","journal-title":"J clin oncol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"CD005007","DOI":"10.1002\/14651858.CD005007.pub4","volume":"4","author":"Bennett","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.jconrel.2019.12.028","volume":"319","author":"Wang","year":"2020","journal-title":"J Contr Rel"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1700250","DOI":"10.1002\/adfm.201700250","volume":"27","author":"Shen","year":"2017","journal-title":"Adv Funct Mater"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"137964","DOI":"10.1016\/j.cej.2022.137964","volume":"450","author":"Hu","year":"2022","journal-title":"Chem Eng J"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"3202","DOI":"10.1021\/nn405773r","volume":"8","author":"Prasad","year":"2014","journal-title":"ACS Nano"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1186\/s12951-022-01441-6","volume":"20","author":"Li","year":"2022","journal-title":"J Nanobiotech"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"101317","DOI":"10.1016\/j.nantod.2021.101317","volume":"41","author":"Zhang","year":"2021","journal-title":"Nano Today"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"119513","DOI":"10.1016\/j.ijpharm.2020.119513","volume":"585","author":"Nie","year":"2020","journal-title":"Int J Pharm"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1080\/10717544.2019.1631409","volume":"26","author":"Zeng","year":"2019","journal-title":"Drug Deliv"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.bios.2018.08.004","volume":"121","author":"Liu","year":"2018","journal-title":"Biosens Bioelectron"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"1605926","DOI":"10.1002\/adfm.201605926","volume":"27","author":"Liu","year":"2017","journal-title":"Adv Funct Mater"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1016\/j.cej.2018.09.076","volume":"356","author":"Bi","year":"2019","journal-title":"Chem Eng J"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"3267","DOI":"10.1007\/s12274-016-1205-8","volume":"9","author":"Yi","year":"2016","journal-title":"Nano Res"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"2203734","DOI":"10.1002\/adma.202203734","volume":"34","author":"Hua","year":"2022","journal-title":"Adv Mater"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.biomaterials.2019.01.004","volume":"197","author":"Li","year":"2019","journal-title":"Biomaterials"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"101708","DOI":"10.1016\/j.nantod.2022.101708","volume":"48","author":"Zhang","year":"2023","journal-title":"Nano Today"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"107744","DOI":"10.1016\/j.cclet.2022.107744","volume":"34","author":"Chen","year":"2023","journal-title":"Chin Chem Lett"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1900047","DOI":"10.1002\/adhm.201900047","volume":"8","author":"Fu","year":"2019","journal-title":"Adv Healthc Mater"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"108460","DOI":"10.1016\/j.cclet.2023.108460","volume":"35","author":"Zheng","year":"2024","journal-title":"Chin Chem Lett"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12951-020-00684-5","volume":"18","author":"Choi","year":"2020","journal-title":"J Nanobiotech"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"22096","DOI":"10.1021\/acsami.9b03004","volume":"11","author":"Xu","year":"2019","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1901819","DOI":"10.1002\/adhm.201901819","volume":"9","author":"Lyu","year":"2020","journal-title":"Adv Healthc Mater"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"15066","DOI":"10.1039\/d0nj02387f","volume":"44","author":"Chen","year":"2020","journal-title":"New J Chem"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"26254","DOI":"10.1002\/anie.202112128","volume":"60","author":"Wang","year":"2021","journal-title":"Angewandte Chemie - Int Ed"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"188","DOI":"10.52568\/000638\/jcsp\/42.02.2020","volume":"42","author":"Guan","year":"2020","journal-title":"J Chem Soc Pak"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"101809","DOI":"10.1016\/j.nantod.2023.101809","volume":"49","author":"Yang","year":"2023","journal-title":"Nano Today"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"2959","DOI":"10.1016\/j.cclet.2021.12.096","volume":"33","author":"Jiang","year":"2022","journal-title":"Chin Chem Lett"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"5155","DOI":"10.7150\/thno.73039","volume":"12","author":"Xu","year":"2022","journal-title":"Theranostics"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1905271","DOI":"10.1002\/adma.201905271","volume":"31","author":"Chang","year":"2019","journal-title":"Adv Mater"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/braincomms\/fcad356","volume":"3","author":"Ozougwu","year":"2016","journal-title":"Int J Res Pharm Biosci"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1097\/WOX.0b013e3182439613","volume":"5","author":"Birben","year":"2012","journal-title":"World Allergy Organ J"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"8281","DOI":"10.1007\/s12274-022-4471-7","volume":"15","author":"Xie","year":"2022","journal-title":"Nano Res"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"2006892","DOI":"10.1002\/adma.202006892","volume":"33","author":"Fu","year":"2021","journal-title":"Adv Mater"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1016\/j.matt.2019.03.007","volume":"1","author":"Wu","year":"2019","journal-title":"Matter"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"2292","DOI":"10.1039\/d2bm01915a","volume":"11","author":"Lai","year":"2023","journal-title":"Biomater Sci"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"3381","DOI":"10.1021\/acs.jmedchem.0c02250","volume":"64","author":"Chen","year":"2021","journal-title":"J Med Chem"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1667\/RR3185.1","volume":"179","author":"Rezaee","year":"2013","journal-title":"Radiat Res"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"17505","DOI":"10.1021\/acs.jpcc.7b05271","volume":"121","author":"Dong","year":"2017","journal-title":"J Phys Chem C"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"4595","DOI":"10.1016\/j.cclet.2022.03.105","volume":"33","author":"Qi","year":"2022","journal-title":"Chin Chem Lett"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"100960","DOI":"10.1016\/j.nantod.2020.100960","volume":"35","author":"Zhang","year":"2020","journal-title":"Nano Today"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"5680","DOI":"10.1021\/acsami.9b23325","volume":"12","author":"Zhang","year":"2020","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"2000589","DOI":"10.1002\/smll.202000589","volume":"16","author":"Wang","year":"2020","journal-title":"Small"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1016\/j.jconrel.2021.01.036","volume":"331","author":"Wang","year":"2021","journal-title":"J Control Release"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"4169","DOI":"10.1016\/j.cclet.2022.02.049","volume":"33","author":"Yu","year":"2022","journal-title":"Chin Chem Lett"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/96858","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/96858","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T11:05:15Z","timestamp":1730372715000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/tme-activated-mno2pt-nanoplatform-of-hydroxyl-radical-and-oxygen-gener-peer-reviewed-fulltext-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":53,"URL":"https:\/\/doi.org\/10.2147\/ijn.s474098","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11]]}}}