{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T18:51:28Z","timestamp":1792867888429,"version":"4.5.0"},"reference-count":59,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s477587","type":"journal-article","created":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T22:10:15Z","timestamp":1729030215000},"page":"10415-10434","source":"Crossref","is-referenced-by-count":20,"title":["Yam Carbon Dots Promote Bone Defect Repair by Modulating Histone Demethylase 4B"],"prefix":"10.2147","volume":"Volume 19","author":[{"given":"QianYang","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MeiChen","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HaiBo","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8880-1301","authenticated-orcid":true,"given":"WeiDong","family":"Niu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2129-8905","authenticated-orcid":true,"given":"LiNa","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2024,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1737","DOI":"10.3390\/biom12121737","volume":"12","author":"Lyu","year":"2022","journal-title":"Biomolecules"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"128200","DOI":"10.1016\/j.ijbiomac.2023.128200","volume":"259","author":"Liu","year":"2024","journal-title":"Int J Biol Macromol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.bioactmat.2022.03.021","volume":"18","author":"Li","year":"2022","journal-title":"Bioact Mater"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"e1964","DOI":"10.1002\/wnan.1964","volume":"16","author":"Yu","year":"2024","journal-title":"Wiley Interdiscip Rev Nanomed Nanobiotechnol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"700","DOI":"10.3390\/gels9090700","volume":"9","author":"Ji","year":"2023","journal-title":"Gels"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1021\/acs.molpharmaceut.3c00703","volume":"21","author":"Chen","year":"2024","journal-title":"Mol Pharm"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1308004","DOI":"10.3389\/fbioe.2023.1308004","volume":"11","author":"Sun","year":"2023","journal-title":"Front Bioeng Biotechnol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/odi.14702","author":"Fu","year":"2023","journal-title":"Oral Dis"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1016\/j.jcis.2020.10.015","volume":"584","author":"Sun","year":"2021","journal-title":"J Colloid Interface Sci"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1039\/d0na00479k","volume":"3","author":"Javed","year":"2020","journal-title":"Nanoscale Adv"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"e1617","DOI":"10.1002\/wnan.1617","volume":"12","author":"Ali","year":"2020","journal-title":"Wiley Interdiscip Rev Nanomed Nanobiotechnol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"e2301013","DOI":"10.1002\/smtd.202301013","volume":"8","author":"Ran","year":"2024","journal-title":"Small Methods"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002\/mabi.201600271","volume":"17","author":"Gogoi","year":"2017","journal-title":"Macromol Biosci"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1016\/j.actbio.2023.01.028","volume":"159","author":"Lee","year":"2023","journal-title":"Acta Biomater"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.3762\/bjnano.13.93","volume":"13","author":"Kanwal","year":"2022","journal-title":"Beilstein J Nanotechnol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1830","DOI":"10.3390\/molecules28041830","volume":"28","author":"Zhang","year":"2023","journal-title":"Molecules"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"2720","DOI":"10.3390\/molecules28062720","volume":"28","author":"Chen","year":"2023","journal-title":"Molecules"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"9049","DOI":"10.2147\/IJN.S281976","volume":"15","author":"Zhao","year":"2020","journal-title":"Int J Nanomed"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1112793","DOI":"10.3389\/fnut.2023.1112793","volume":"10","author":"Riek\u00f6tter","year":"2023","journal-title":"Front Nutr"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1007\/s00425-020-03458-3","volume":"252","author":"Epping","year":"2020","journal-title":"Planta"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.foodres.2019.04.016","volume":"122","author":"Zhang","year":"2019","journal-title":"Food Res Int"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.jconrel.2023.01.071","volume":"355","author":"Hwang","year":"2023","journal-title":"J Control Release"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"194","DOI":"10.3746\/pnf.2014.19.3.194","volume":"19","author":"Kim","year":"2014","journal-title":"Prev Nutr Food Sci"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1111\/cas.16005","volume":"115","author":"Ni","year":"2024","journal-title":"Cancer Sci"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"790129","DOI":"10.3389\/fcell.2021.790129","volume":"9","author":"Wang","year":"2022","journal-title":"Front Cell Dev Biol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1007\/s10528-021-10042-1","volume":"59","author":"Zhang","year":"2021","journal-title":"Biochem Genet"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1002\/stem.2231","volume":"34","author":"Lee","year":"2016","journal-title":"Stem Cells"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1016\/j.stem.2021.01.010","volume":"28","author":"Deng","year":"2021","journal-title":"Cell Stem Cell"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"e1954","DOI":"10.1002\/wnan.1954","volume":"16","author":"Liu","year":"2024","journal-title":"Wiley Interdiscip Rev Nanomed Nanobiotechnol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.jconrel.2007.03.022","volume":"121","author":"Champion","year":"2007","journal-title":"J Control Release"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1016\/j.drudis.2018.10.006","volume":"24","author":"Yang","year":"2019","journal-title":"Drug Discov Today"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"2772","DOI":"10.3390\/molecules28062772","volume":"28","author":"Giordano","year":"2023","journal-title":"Molecules"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1016\/j.actbio.2023.07.006","volume":"168","author":"Shen","year":"2023","journal-title":"Acta Biomater"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/j.actbio.2020.07.022","volume":"114","author":"Dehvari","year":"2020","journal-title":"Acta Biomater"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.3390\/foods9091304","volume":"9","author":"Obidiegwu","year":"2020","journal-title":"Foods"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"815479","DOI":"10.3389\/fphar.2022.815479","volume":"13","author":"Li","year":"2022","journal-title":"Front Pharmacol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1186\/s12951-023-01795-5","volume":"21","author":"Wang","year":"2023","journal-title":"J Nanobiotechnology"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"6503","DOI":"10.2147\/IJN.S431061","volume":"18","author":"Zeng","year":"2023","journal-title":"Int J Nanomed"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1080\/21691401.2023.2239522","volume":"52","author":"Zhao","year":"2024","journal-title":"Artif Cells Nanomed Biotechnol"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"8527","DOI":"10.1021\/acsami.3c18418","volume":"16","author":"Zhu","year":"2024","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"120784","DOI":"10.1016\/j.carbpol.2023.120784","volume":"311","author":"Wen","year":"2023","journal-title":"Carbohydr Polym"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"1118550","DOI":"10.3389\/fphar.2023.1118550","volume":"14","author":"Zhang","year":"2023","journal-title":"Front Pharmacol"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"20726","DOI":"10.1021\/acsami.3c01322","volume":"15","author":"Guo","year":"2023","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"2031","DOI":"10.1021\/acsabm.1c01215","volume":"5","author":"Zhu","year":"2022","journal-title":"ACS Appl Bio Mater"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"869422","DOI":"10.3389\/fimmu.2022.869422","volume":"13","author":"Bordukalo-Nik\u0161i\u0107","year":"2022","journal-title":"Front Immunol"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"155337","DOI":"10.1016\/j.metabol.2022.155337","volume":"138","author":"Liu","year":"2023","journal-title":"Metabolism"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1016\/j.freeradbiomed.2023.08.020","volume":"208","author":"Yang","year":"2023","journal-title":"Free Radic Biol Med"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"e2301366","DOI":"10.1002\/adhm.202301366","volume":"12","author":"Luo","year":"2023","journal-title":"Adv Healthc Mater"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2024.01.018","volume":"17","author":"Gong","year":"2024","journal-title":"J Adv Res"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1038\/s41368-018-0015-0","volume":"10","author":"Hirai","year":"2018","journal-title":"Int J Oral Sci"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1186\/s13148-023-01608-4","volume":"15","author":"Wang","year":"2023","journal-title":"Clin Epigenetics"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"2129","DOI":"10.1002\/jcp.29117","volume":"235","author":"Sha","year":"2020","journal-title":"J Cell Physiol"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.stem.2012.04.009","volume":"11","author":"Ye","year":"2012","journal-title":"Cell Stem Cell"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/j.yexcr.2018.11.027","volume":"374","author":"Yang","year":"2019","journal-title":"Exp Cell Res"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1002\/biof.1670","volume":"46","author":"Zhang","year":"2020","journal-title":"Biofactors"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"E8","DOI":"10.3171\/2010.9.FOCUS10201","volume":"29","author":"Szpalski","year":"2010","journal-title":"Neurosurg Focus"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1538\/expanim.21-0049","volume":"71","author":"Asada","year":"2022","journal-title":"Exp Anim"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.jconrel.2012.12.015","volume":"166","author":"Wang","year":"2013","journal-title":"J Control Release"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"2075","DOI":"10.1021\/acs.biomac.3c00279","volume":"25","author":"Mamidi","year":"2024","journal-title":"Biomacromolecules"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/96434","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/96434","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T22:10:17Z","timestamp":1729030217000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/yam-carbon-dots-promote-bone-defect-repair-by-modulating-histone-demet-peer-reviewed-fulltext-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":59,"URL":"https:\/\/doi.org\/10.2147\/ijn.s477587","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10]]}}}