{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:51:47Z","timestamp":1790013107835,"version":"4.0.1"},"reference-count":57,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s485084","type":"journal-article","created":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T05:00:12Z","timestamp":1729832412000},"page":"10839-10856","source":"Crossref","is-referenced-by-count":3,"title":["Polyoxometalates Ameliorate Metabolic Dysfunction-Associated Steatotic Liver Disease by Activating the AMPK Signaling Pathway"],"prefix":"10.2147","volume":"Volume 19","author":[{"given":"Dandan","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingguo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zequn","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengbao","family":"Zha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3880-9070","authenticated-orcid":true,"given":"Yajun","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2024,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1002\/hep.29466","volume":"67","author":"Estes","year":"2018","journal-title":"Hepatology"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.1172\/jci23621","volume":"115","author":"Donnelly","year":"2005","journal-title":"J Clin Invest"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1503\/cmaj.045232","volume":"172","author":"Adams","year":"2005","journal-title":"Cmaj"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"37","DOI":"10.3390\/cells9010037","volume":"9","author":"Boeckmans","year":"2019","journal-title":"Cells"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.metabol.2017.04.011","volume":"72","author":"Reccia","year":"2017","journal-title":"Metabolism"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1038\/nrendo.2016.124","volume":"12","author":"Baiceanu","year":"2016","journal-title":"Nat Rev Endocrinol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1146\/annurev-pathmechdis-012418-013003","volume":"14","author":"Cai","year":"2019","journal-title":"Annu Rev Pathol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1016\/j.jhep.2013.12.012","volume":"60","author":"Casta\u00f1o","year":"2014","journal-title":"J Hepatol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1016\/j.celrep.2018.12.036","volume":"26","author":"Garcia","year":"2019","journal-title":"Cell Rep"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"4617","DOI":"10.1038\/onc.2010.206","volume":"29","author":"Jeninga","year":"2010","journal-title":"Oncogene"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"20015","DOI":"10.1074\/jbc.M802187200","volume":"283","author":"Hou","year":"2008","journal-title":"J Biol Chem"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"E1234","DOI":"10.1152\/ajpendo.00198.2012","volume":"303","author":"Li","year":"2012","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1038\/nature07813","volume":"458","author":"Cant\u00f3","year":"2009","journal-title":"Nature"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.cmet.2009.02.006","volume":"9","author":"Purushotham","year":"2009","journal-title":"Cell Metab"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1868","DOI":"10.1128\/mcb.20.5.1868-1876.2000","volume":"20","author":"Vega","year":"2000","journal-title":"Mol Cell Biol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"154589","DOI":"10.1016\/j.phymed.2022.154589","volume":"109","author":"Zhang","year":"2023","journal-title":"Phytomedicine"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/s40820-020-00550-x","volume":"13","author":"Jin","year":"2020","journal-title":"Nanomicro Lett"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1016\/j.jhep.2015.10.020","volume":"64","author":"Or\u00f3","year":"2016","journal-title":"J Hepatol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"2449","DOI":"10.1016\/j.nano.2016.07.002","volume":"12","author":"Cao","year":"2016","journal-title":"Nanomedicine"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"6997","DOI":"10.2147\/ijn.S145951","volume":"12","author":"Poilil Surendran","year":"2017","journal-title":"Int J Nanomed"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"132","DOI":"10.3109\/07388551.2014.930017","volume":"36","author":"Kang","year":"2016","journal-title":"Crit Rev Biotechnol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/j.semcancer.2019.09.025","volume":"69","author":"Moosavian","year":"2021","journal-title":"Semin Cancer Biol"},{"key":"ref23","first-page":"477","volume":"44","author":"Mukherjee","year":"1965","journal-title":"J Indian Med Assoc"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"2980","DOI":"10.1002\/anie.201803868","volume":"58","author":"Bijelic","year":"2019","journal-title":"Angew Chem Int Ed Engl"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"5421","DOI":"10.1038\/s41467-018-07890-8","volume":"9","author":"Ni","year":"2018","journal-title":"Nat Commun"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"2126","DOI":"10.1021\/acsnano.9b08894","volume":"14","author":"Zhou","year":"2020","journal-title":"ACS Nano"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"18032","DOI":"10.1002\/anie.201910521","volume":"58","author":"Zhao","year":"2019","journal-title":"Angew Chem Int Ed Engl"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"560905","DOI":"10.3389\/fphar.2020.560905","volume":"11","author":"Li","year":"2020","journal-title":"Front Pharmacol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1124\/jpet.111.184341","volume":"339","author":"Mei","year":"2011","journal-title":"J Pharmacol Exp Ther"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"23667","DOI":"10.1074\/jbc.M112.350181","volume":"287","author":"Duan","year":"2012","journal-title":"J Biol Chem"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"16977","DOI":"10.1074\/jbc.M116.740092","volume":"291","author":"Yu","year":"2016","journal-title":"J Biol Chem"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"9520","DOI":"10.1074\/jbc.M111421200","volume":"277","author":"Liang","year":"2002","journal-title":"J Biol Chem"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"5419","DOI":"10.1073\/pnas.0830671100","volume":"100","author":"Laffitte","year":"2003","journal-title":"Proc Natl Acad Sci"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"11019","DOI":"10.1074\/jbc.M111041200","volume":"277","author":"Joseph","year":"2002","journal-title":"J Biol Chem"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1172\/jci15593","volume":"109","author":"Horton","year":"2002","journal-title":"J Clin Invest"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1038\/nrm.2017.95","volume":"19","author":"Herzig","year":"2018","journal-title":"Nat Rev Mol Cell Biol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1023\/B:REMD.0000021433.63915.bb","volume":"5","author":"Hardie","year":"2004","journal-title":"Rev Endocr Metab Disord"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1645","DOI":"10.1016\/s0016-5085(96)70028-8","volume":"111","author":"Weltman","year":"1996","journal-title":"Gastroenterology"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1093\/toxsci\/kfx253","volume":"161","author":"Li","year":"2018","journal-title":"Toxicol Sci"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1301\/002966402320387224","volume":"60","author":"Mehta","year":"2002","journal-title":"Nutr Rev"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/s2213-8587(18)30154-2","volume":"7","author":"Stefan","year":"2019","journal-title":"Lancet Diabetes Endocrinol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1002\/hep.29229","volume":"66","author":"Li","year":"2017","journal-title":"Hepatology"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"3313","DOI":"10.1007\/s00018-018-2860-6","volume":"75","author":"Ipsen","year":"2018","journal-title":"Cell Mol Life Sci"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1038\/415339a","volume":"415","author":"Minokoshi","year":"2002","journal-title":"Nature"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"3407","DOI":"10.1007\/s00018-010-0454-z","volume":"67","author":"Cant\u00f3","year":"2010","journal-title":"Cell Mol Life Sci"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"14946","DOI":"10.1096\/fj.202001234R","volume":"34","author":"Liu","year":"2020","journal-title":"FASEB j"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1038\/s41419-019-1858-9","volume":"10","author":"Wang","year":"2019","journal-title":"Cell Death Dis"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1016\/j.tem.2017.05.004","volume":"28","author":"Day","year":"2017","journal-title":"Trends Endocrinol Metab"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"2313641","DOI":"10.1155\/2020\/2313641","volume":"2020","author":"Zhai","year":"2020","journal-title":"Oxid Med Cell Longev"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"585582","DOI":"10.3389\/fphar.2020.585582","volume":"11","author":"Zhu","year":"2020","journal-title":"Front Pharmacol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1053\/j.gastro.2016.09.017","volume":"152","author":"Besse-Patin","year":"2017","journal-title":"Gastroenterology"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"12017","DOI":"10.1073\/pnas.0705070104","volume":"104","author":"J\u00e4ger","year":"2007","journal-title":"Proc Natl Acad Sci"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"810619","DOI":"10.4061\/2011\/810619","volume":"2011","author":"Wenz","year":"2011","journal-title":"J Aging Res"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/j.jnutbio.2011.09.006","volume":"23","author":"Nomura","year":"2012","journal-title":"J Nutr Biochem"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"2047","DOI":"10.1128\/mcb.01658-12","volume":"33","author":"He","year":"2013","journal-title":"Mol Cell Biol"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1186\/s12876-015-0298-y","volume":"15","author":"Pierce","year":"2015","journal-title":"BMC Gastroenterol"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"2189","DOI":"10.1002\/hep.26271","volume":"57","author":"Hatting","year":"2013","journal-title":"Hepatology"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/96698","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/96698","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T05:00:14Z","timestamp":1729832414000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/polyoxometalates-ameliorate-metabolic-dysfunction-associated-steatotic-peer-reviewed-fulltext-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":57,"URL":"https:\/\/doi.org\/10.2147\/ijn.s485084","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10]]}}}