{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T11:59:12Z","timestamp":1791547152167,"version":"4.3.4"},"reference-count":58,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s502192","type":"journal-article","created":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T11:50:14Z","timestamp":1741348214000},"page":"2879-2899","source":"Crossref","is-referenced-by-count":15,"title":["Human Umbilical Cord Mesenchymal Stem Cells-Derived Exosomes Attenuates Experimental Periodontitis in Mice Partly by Delivering miRNAs"],"prefix":"10.2147","volume":"Volume 20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-1027-2995","authenticated-orcid":true,"given":"Ke","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoli","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5564-7344","authenticated-orcid":true,"given":"Jinlei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linyuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1038\/s41577-020-00488-6","volume":"21","author":"Hajishengallis","year":"2021","journal-title":"Nat Rev Immunol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"510","DOI":"10.20471\/acc.2021.60.03.22","volume":"60","author":"Rin\u010di\u0107","year":"2022","journal-title":"Acta Clin Croat"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"4683","DOI":"10.2147\/ijn.S420967","volume":"18","author":"Qiao","year":"2023","journal-title":"Int J Nanomed"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1007\/s12035-022-03088-8","volume":"60","author":"Shen","year":"2023","journal-title":"mol Neurobiol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/s40364-019-0159-x","volume":"7","author":"Yin","year":"2019","journal-title":"Biomark Res"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1186\/s13287-024-04028-0","volume":"15","author":"Lu","year":"2024","journal-title":"Stem Cell Res Ther"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"10421","DOI":"10.3390\/ijms231810421","volume":"23","author":"Teng","year":"2022","journal-title":"Int J mol Sci"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1252","DOI":"10.1007\/s12015-023-10521-5","volume":"19","author":"Hu","year":"2023","journal-title":"Stem Cell Rev Rep"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1327495","DOI":"10.3389\/fendo.2023.1327495","volume":"14","author":"Gao","year":"2023","journal-title":"Front Endocrinol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1441733","DOI":"10.3389\/fimmu.2024.1441733","volume":"15","author":"Zabalza","year":"2024","journal-title":"Front Immunol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/s13287-021-02696-w","volume":"13","author":"Peng","year":"2022","journal-title":"Stem Cell Res Ther"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1016\/j.actbio.2020.12.046","volume":"122","author":"Nakao","year":"2021","journal-title":"Acta Biomater"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1186\/s13046-022-02499-8","volume":"41","author":"Qiu","year":"2022","journal-title":"J Exp Clin Cancer Res"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1186\/s13046-019-1511-6","volume":"39","author":"Wei","year":"2020","journal-title":"J Exp Clin Cancer Res"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1186\/s12951-021-00991-5","volume":"19","author":"Xing","year":"2021","journal-title":"J Nanobiotechnology"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"100365","DOI":"10.1016\/j.mtbio.2022.100365","volume":"16","author":"Jiang","year":"2022","journal-title":"Mater Today Bio"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"e2309491","DOI":"10.1002\/advs.202309491","volume":"11","author":"Liu","year":"2024","journal-title":"Adv Sci"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3390\/ma16134805","volume":"16","author":"Li","year":"2023","journal-title":"Materials"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"3821","DOI":"10.1039\/d1bm00346a","volume":"9","author":"Wang","year":"2021","journal-title":"Biomater Sci"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"20","DOI":"10.3390\/md20010020","volume":"20","author":"Mohammadpour","year":"2021","journal-title":"Mar Drugs"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1007\/s40204-022-00199-2","volume":"11","author":"Chenicheri","year":"2022","journal-title":"Prog Biomater"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"111671","DOI":"10.1016\/j.msec.2020.111671","volume":"120","author":"Zhang","year":"2021","journal-title":"Mater Sci Eng C Mater Biol Appl"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"14339","DOI":"10.1080\/21655979.2022.2085388","volume":"13","author":"Zhang","year":"2022","journal-title":"Bioengineered"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"1247448","DOI":"10.3389\/fbioe.2023.1247448","volume":"11","author":"Ren","year":"2023","journal-title":"Front Bioeng Biotechnol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"8399","DOI":"10.1021\/acsnano.2c02900","volume":"16","author":"Yan","year":"2022","journal-title":"ACS Nano"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.jim.2013.05.002","volume":"394","author":"Abe","year":"2013","journal-title":"J Immunol Methods"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"2156","DOI":"10.1016\/j.mex.2019.09.004","volume":"6","author":"Pereira","year":"2019","journal-title":"MethodsX"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1007\/978-1-0716-0939-2_23","volume":"2210","author":"Tamura","year":"2021","journal-title":"Methods mol Biol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"6857","DOI":"10.2147\/ijn.S465089","volume":"19","author":"Wang","year":"2024","journal-title":"Int J Nanomed"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/s13287-023-03242-6","volume":"14","author":"Chen","year":"2023","journal-title":"Stem Cell Res Ther"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1038\/s41368-021-00150-4","volume":"13","author":"Zhang","year":"2021","journal-title":"Int J Oral Sci"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1168","DOI":"10.3390\/cells11071168","volume":"11","author":"Shaikh","year":"2022","journal-title":"Cells"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1186\/s13287-021-02529-w","volume":"12","author":"Shareghi-Oskoue","year":"2021","journal-title":"Stem Cell Res Ther"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1186\/s13287-022-02811-5","volume":"13","author":"Guo","year":"2022","journal-title":"Stem Cell Res Ther"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"750990","DOI":"10.3389\/fgene.2021.750990","volume":"12","author":"Mai","year":"2021","journal-title":"Front Genet"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"181","DOI":"10.3389\/fcell.2020.00181","volume":"8","author":"El Baradie","year":"2020","journal-title":"Front Cell Dev Biol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1186\/s13287-021-02276-y","volume":"12","author":"Peng","year":"2021","journal-title":"Stem Cell Res Ther"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"6917","DOI":"10.2147\/ijn.S264498","volume":"15","author":"Zhang","year":"2020","journal-title":"Int J Nanomed"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"e2400049","DOI":"10.1002\/adhm.202400049","volume":"13","author":"Zhao","year":"2024","journal-title":"Adv Healthc Mater"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1038\/s41536-023-00286-3","volume":"8","author":"Wen","year":"2023","journal-title":"NPJ Regen Med"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1002\/jcp.29004","volume":"235","author":"Abbaszadeh","year":"2020","journal-title":"J Cell Physiol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s12964-022-01017-9","volume":"21","author":"Oveili","year":"2023","journal-title":"Cell Commun Signal"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"7167","DOI":"10.3390\/ijms23137167","volume":"23","author":"Ho","year":"2022","journal-title":"Int J mol Sci"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.semcancer.2008.01.005","volume":"18","author":"Sonkoly","year":"2008","journal-title":"Semin Cancer Biol"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1089\/ten.TEA.2020.0141","volume":"27","author":"Liu","year":"2021","journal-title":"Tissue Eng Part A"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"105125","DOI":"10.1016\/j.archoralbio.2021.105125","volume":"126","author":"Rovas","year":"2021","journal-title":"Arch Oral Biol"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1002\/jper.18-0729","volume":"90","author":"Nisha","year":"2019","journal-title":"J Periodontol"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1016\/j.tcb.2008.07.007","volume":"18","author":"Roush","year":"2008","journal-title":"Trends Cell Biol"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"879877","DOI":"10.3389\/fcell.2022.879877","volume":"10","author":"Liu","year":"2022","journal-title":"Front Cell Dev Biol"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"2182","DOI":"10.7150\/ijbs.33490","volume":"15","author":"Shen","year":"2019","journal-title":"Int J Biol Sci"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"626","DOI":"10.3892\/ol.2021.12887","volume":"22","author":"Fu","year":"2021","journal-title":"Oncol Lett"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1515\/biol-2020-0088","volume":"15","author":"Chen","year":"2020","journal-title":"Open Life Sci"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1080\/03008207.2020.1752200","volume":"62","author":"Niu","year":"2021","journal-title":"Connect Tissue Res"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"3000","DOI":"10.3390\/cells10113000","volume":"10","author":"Iwaszko","year":"2021","journal-title":"Cells"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.1016\/j.biochi.2009.07.003","volume":"91","author":"Krasnikov","year":"2009","journal-title":"Biochimie"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"2946","DOI":"10.1111\/j.1742-4658.2007.05828.x","volume":"274","author":"Lin","year":"2007","journal-title":"Febs j"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1186\/s12951-022-01314-y","volume":"20","author":"Chen","year":"2022","journal-title":"J Nanobiotechnology"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"1113","DOI":"10.1016\/j.bioactmat.2020.07.002","volume":"5","author":"Shen","year":"2020","journal-title":"Bioact Mater"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/100916","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/100916","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T11:50:17Z","timestamp":1741348217000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/human-umbilical-cord-mesenchymal-stem-cells-derived-exosomes-attenuate-peer-reviewed-fulltext-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":58,"URL":"https:\/\/doi.org\/10.2147\/ijn.s502192","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3]]}}}