{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T04:29:49Z","timestamp":1789273789003,"version":"build-2803163510"},"reference-count":46,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s509798","type":"journal-article","created":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T10:25:11Z","timestamp":1741947911000},"page":"3235-3249","source":"Crossref","is-referenced-by-count":9,"title":["Enhanced Dermal Delivery of Nanoparticulate Formulation of Cutibacterium acnes Using Sponge Spicules for Atopic Dermatitis Treatment"],"prefix":"10.2147","volume":"Volume 20","author":[{"given":"Youmei","family":"Jin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-7198-978X","authenticated-orcid":true,"given":"Mengnan","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8397-2184","authenticated-orcid":true,"given":"Ming","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1542\/peds.111.3.608","volume":"111","author":"Eichenfield","year":"2003","journal-title":"Pediatrics"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1111\/bjd.19580","volume":"184","author":"Laughter","year":"2020","journal-title":"Br J Dermatol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/j.iac.2010.06.005","volume":"30","author":"Wollenberg","year":"2010","journal-title":"Immunol Allergy Clin North Am"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1111\/jdv.15973","volume":"34","author":"Yosipovitch","year":"2019","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref5","first-page":"590","volume":"101","author":"Frazier","year":"2020","journal-title":"Am Fam Physician"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1111\/imm.13120","volume":"158","author":"Furue","year":"2019","journal-title":"Immunology"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"e2014444118","DOI":"10.1073\/pnas.2014444118","volume":"118","author":"Towell","year":"2020","journal-title":"Proc Natl Acad Sci"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1248\/bpb.b19-00088","volume":"43","author":"Fujii","year":"2020","journal-title":"Biol Pharm Bull"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1111\/bjd.14357","volume":"175","author":"Kim","year":"2016","journal-title":"Br J Dermatol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"4130","DOI":"10.3390\/ijms22084130","volume":"22","author":"Sroka-Tomaszewska","year":"2021","journal-title":"Int J mol Sci"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"79","DOI":"10.5415\/apallergy.2013.3.2.79","volume":"3","author":"Kim","year":"2013","journal-title":"Asia Pacific Allergy"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"235","DOI":"10.2217\/fmb-2022-0191","volume":"18","author":"Boyanova","year":"2023","journal-title":"Future Microbiol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1111\/jdv.15043","volume":"32","author":"Dreno","year":"2018","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"21237","DOI":"10.1038\/s41598-020-77790-9","volume":"10","author":"Nakamura","year":"2020","journal-title":"Sci Rep"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"490","DOI":"10.2340\/00015555-2896","volume":"98","author":"Francuzik","year":"2018","journal-title":"Acta Derm Venereol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"628","DOI":"10.3390\/microorganisms9030628","volume":"9","author":"Rozas","year":"2021","journal-title":"Microorganisms"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1111\/jdv.14374","volume":"31","author":"Dreno","year":"2017","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/s10753-018-0870-z","volume":"42","author":"Zhu","year":"2018","journal-title":"Inflammation"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1038\/jid.2014.290","volume":"135","author":"Kistowska","year":"2015","journal-title":"J Invest Dermatol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1111\/j.1600-0625.2010.01180.x","volume":"20","author":"Kitagawa","year":"2011","journal-title":"Experimental Dermatol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1007\/s12325-009-0075-9","volume":"26","author":"Ale","year":"2009","journal-title":"Adv Ther"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.jconrel.2021.11.025","volume":"341","author":"Sabbagh","year":"2022","journal-title":"J Control Release"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1038\/nbt.1504","volume":"26","author":"Prausnitz","year":"2008","journal-title":"Nat Biotechnol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1080\/17425247.2020.1713087","volume":"17","author":"Kovacik","year":"2020","journal-title":"Expert Opin Drug Deliv"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1080\/17425247.2023.2209719","volume":"20","author":"Andrade","year":"2023","journal-title":"Expert Opin Drug Deliv"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.ultras.2013.07.007","volume":"54","author":"Park","year":"2014","journal-title":"Ultrasonics"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1080\/17425247.2020.1745772","volume":"17","author":"Dermol-Cerne","year":"2020","journal-title":"Expert Opin Drug Deliv"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.ymeth.2021.07.009","volume":"199","author":"Lima","year":"2022","journal-title":"Methods"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.3762\/bjnano.12.77","volume":"12","author":"Faraji Rad","year":"2021","journal-title":"Beilstein J Nanotechnol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"3188","DOI":"10.1021\/acs.molpharmaceut.7b00468","volume":"14","author":"Zhang","year":"2017","journal-title":"Mol Pharm"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1039\/C8BM01555D","volume":"7","author":"Zhang","year":"2019","journal-title":"Biomater Sci"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"2859","DOI":"10.2147\/IJN.S249751","volume":"15","author":"Yu","year":"2020","journal-title":"Int J Nanomed"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"2119","DOI":"10.3390\/pharmaceutics13122119","volume":"13","author":"Zhang","year":"2021","journal-title":"Pharmaceutics"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1016\/j.omtn.2020.04.003","volume":"20","author":"Liang","year":"2020","journal-title":"mol Ther Nucleic Acids"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/S0022-3565(25)08751-8","volume":"82","author":"Draize","year":"1944","journal-title":"J Pharmacol Exp Ther"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1007\/s10068-018-0499-6","volume":"28","author":"Herrera-Rodr\u00edguez","year":"2018","journal-title":"Food Sci Biotechnol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1016\/j.jaci.2022.10.023","volume":"151","author":"Schuler","year":"2023","journal-title":"J Allergy Clin Immunol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1038\/nri3073","volume":"11","author":"Murray","year":"2011","journal-title":"Nat Rev Immunol"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1016\/j.cell.2010.03.006","volume":"140","author":"Medzhitov","year":"2010","journal-title":"Cell"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1038\/nature07201","volume":"454","author":"Medzhitov","year":"2008","journal-title":"Nature"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1111\/j.1087-0024.2004.00829.x","volume":"9","author":"Biedermann","year":"2004","journal-title":"J Invest Dermatol Symp Proc"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"68","DOI":"10.2174\/1871523011312010009","volume":"12","author":"Roubille","year":"2013","journal-title":"Antiinflamm Antiallergy Agents Med Chem"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"2155","DOI":"10.3390\/ijms19082155","volume":"19","author":"Bent","year":"2018","journal-title":"Int J mol Sci"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"11736","DOI":"10.1073\/pnas.0604575103","volume":"103","author":"Li","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"47","DOI":"10.3390\/antib9030047","volume":"9","author":"Pellefigues","year":"2020","journal-title":"Antibodies"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"254","DOI":"10.3389\/fimmu.2018.00254","volume":"9","author":"Kasperkiewicz","year":"2018","journal-title":"Front Immunol"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/101140","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/101140","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T10:25:14Z","timestamp":1741947914000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/enhanced-dermal-delivery-of-nanoparticulate-formulation-of-cutibacteri-peer-reviewed-fulltext-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":46,"URL":"https:\/\/doi.org\/10.2147\/ijn.s509798","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3]]}}}