{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T05:23:57Z","timestamp":1780723437978,"version":"3.54.1"},"reference-count":128,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s520616","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T12:45:13Z","timestamp":1749473113000},"page":"7271-7294","source":"Crossref","is-referenced-by-count":9,"title":["Multifaceted Applications of Nanomaterials in Colorectal Cancer Management: Screening, Diagnostics, and Therapeutics"],"prefix":"10.2147","volume":"Volume 20","author":[{"given":"He","family":"Xin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihui","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Niu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1136\/gutjnl-2022-327736","volume":"72","author":"Morgan","year":"2023","journal-title":"Gut"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"233","DOI":"10.3322\/caac.21772","volume":"73","author":"Siegel","year":"2023","journal-title":"CA Cancer J Clin"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"229","DOI":"10.3322\/caac.21834","volume":"74","author":"Bray","year":"2024","journal-title":"CA Cancer J Clin"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"e1805391","DOI":"10.1002\/adma.201805391","volume":"31","author":"Yan","year":"2019","journal-title":"Adv Mater"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"4653","DOI":"10.1039\/d0bm00558d","volume":"8","author":"Foulkes","year":"2020","journal-title":"Biomater Sci"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"2491","DOI":"10.1056\/NEJMoa022749","volume":"348","author":"Harisinghani","year":"2003","journal-title":"New Engl J Med"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1016\/j.jmoldx.2018.05.007","volume":"20","author":"Lam","year":"2018","journal-title":"J Mol Diagnostics"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3390\/polym15071596","volume":"15","author":"Yusuf","year":"2023","journal-title":"Polymers"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.1053\/j.gastro.2019.11.304","volume":"158","author":"Mendelsohn","year":"2020","journal-title":"Gastroenterology"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.cdtm.2018.08.004","volume":"4","author":"Li","year":"2018","journal-title":"Chronic Dis Transl Med"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"4142","DOI":"10.1021\/acs.nanolett.2c04914","volume":"23","author":"Ishwar","year":"2023","journal-title":"Nano Lett"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"5090","DOI":"10.1021\/acssensors.4c00774","volume":"9","author":"Liu","year":"2024","journal-title":"ACS Sens"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2023.115993","volume":"248","author":"Jiamin","year":"2024","journal-title":"Biosens Bioelectron"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1021\/acssensors.4c02885","volume":"10","author":"Feng","year":"2025","journal-title":"ACS Sens"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"e740","DOI":"10.1002\/agt2.740","author":"Liu","year":"2025","journal-title":"Aggregate"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1016\/j.ejpb.2010.01.001","volume":"74","author":"Sakuma","year":"2010","journal-title":"Eur J Pharm Biopharm"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"E2288","DOI":"10.1073\/pnas.1211309110","volume":"110","author":"Zavaleta","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"9445","DOI":"10.1038\/srep09445","volume":"5","author":"Xie","year":"2015","journal-title":"Sci Rep"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.jconrel.2015.04.036","volume":"209","author":"Xie","year":"2015","journal-title":"J Control Release"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.3390\/s17081795","volume":"17","author":"Bhattacharyya","year":"2017","journal-title":"Sensors"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"351","DOI":"10.3748\/wjg.v24.i3.351","volume":"24","author":"Kuai","year":"2018","journal-title":"World J Gastroenterol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1624","DOI":"10.7150\/thno.23531","volume":"8","author":"Huang","year":"2018","journal-title":"Theranostics"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"115930","DOI":"10.1016\/j.bmc.2020.115930","volume":"30","author":"Pan","year":"2021","journal-title":"Bioorg Med Chem"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26020466","volume":"26","author":"Astolfi","year":"2021","journal-title":"Molecules"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.3390\/bios12090736","volume":"12","author":"Hanoglu","year":"2022","journal-title":"Biosensors"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"e000355","DOI":"10.1136\/bmjgast-2019-000355","volume":"7","author":"Hariharan","year":"2020","journal-title":"BMJ Open Gastroenterol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/j.mam.2019.06.002","volume":"69","author":"Marcuello","year":"2019","journal-title":"Mol Aspects Med"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15051514","volume":"15","author":"Djermane","year":"2023","journal-title":"Pharmaceutics"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2023.104476","volume":"89","author":"Guo","year":"2023","journal-title":"Ebiomedicine"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"3044","DOI":"10.1158\/0008-5472.CAN-23-3511","volume":"84","author":"Xian","year":"2024","journal-title":"Cancer Res"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"3735","DOI":"10.1007\/s00259-023-06313-1","volume":"50","author":"Liqiang","year":"2023","journal-title":"Eur J Nuclear Med Mol Imaging"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"2305","DOI":"10.1007\/s00259-023-06183-7","volume":"50","author":"Xiao","year":"2023","journal-title":"Eur J Nuclear Med Mol Imaging"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202405275","volume":"36","author":"Zhang","year":"2024","journal-title":"Adv Mater"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.34133\/bmr.0041","volume":"28","author":"Ding","year":"2024","journal-title":"Biomater Res"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1097\/sle.0000000000001194","volume":"33","author":"Ji","year":"2023","journal-title":"Surg Laparosc Endosc Percutan Tech"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1007\/s12032-023-02175-7","volume":"40","author":"Li","year":"2023","journal-title":"Med Oncol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1186\/s12951-023-02171-z","volume":"21","author":"Ma","year":"2023","journal-title":"J Nanobiotechnol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"8909","DOI":"10.7150\/thno.61651","volume":"11","author":"Wang","year":"2021","journal-title":"Theranostics"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"4615","DOI":"10.1007\/s00330-020-07609-8","volume":"31","author":"Dong","year":"2021","journal-title":"Eur Radiol"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1002\/ags3.12061","volume":"2","author":"Matsuda","year":"2018","journal-title":"Ann Gastroenterol Surg"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.1016\/j.surg.2021.08.023","volume":"171","author":"Li","year":"2022","journal-title":"Surgery"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"1445","DOI":"10.1016\/j.dld.2020.08.020","volume":"52","author":"Li","year":"2020","journal-title":"Dig Liver Dis"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1186\/s12957-016-0987-1","volume":"14","author":"Wang","year":"2016","journal-title":"World J Surg Oncol"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"8655","DOI":"10.1039\/d4tb01062k","volume":"12","author":"Yan","year":"2024","journal-title":"J Mater Chem B"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-023-01779-5","volume":"21","author":"Wang","year":"2023","journal-title":"J Nanobiotechnol"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2023.122206","volume":"300","author":"Liang","year":"2023","journal-title":"Biomaterials"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtphys.2023.101150","volume":"36","author":"Zhang","year":"2023","journal-title":"Mat Today Physics"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2023.141819","volume":"460","author":"Lee","year":"2023","journal-title":"Chem Eng J"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1016\/j.actbio.2022.11.043","volume":"157","author":"Xiao","year":"2023","journal-title":"Acta Biomater"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1016\/j.jconrel.2024.01.024","volume":"366","author":"Deng","year":"2024","journal-title":"J Control Release"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202404381","volume":"34","author":"Zhuang","year":"2024","journal-title":"Adv Funct Mater"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"23742","DOI":"10.1021\/acsami.4c02247","volume":"16","author":"de Almeida","year":"2024","journal-title":"ACS App Mater Interfaces"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202401009","volume":"13","author":"Xie","year":"2024","journal-title":"Adv Healthcare Mater"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1016\/j.jcis.2024.01.002","volume":"659","author":"Niu","year":"2024","journal-title":"J Colloid Interface Sci"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"2767","DOI":"10.1007\/s11426-023-1920-0","volume":"67","author":"Axin","year":"2024","journal-title":"Sci China-Chem"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2024.123031","volume":"316","author":"Hui","year":"2025","journal-title":"Biomaterials"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1007\/s42114-024-01141-9","volume":"8","author":"Yan","year":"2025","journal-title":"Adv Composites Hybrid Mat"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"5984","DOI":"10.1021\/acsami.4c18748","volume":"17","author":"Ren","year":"2025","journal-title":"ACS App Mater Interfaces"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202413518","volume":"12","author":"Xiong","year":"2025","journal-title":"Adv Sci"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202404842","author":"Long","year":"2025","journal-title":"Adv Healthcare Mater"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1016\/j.jconrel.2025.01.048","volume":"379","author":"Xin","year":"2025","journal-title":"J Control Release"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2023.101798","volume":"49","author":"Zhang","year":"2023","journal-title":"Nano Today"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1016\/j.actbio.2023.04.001","volume":"164","author":"Huang","year":"2023","journal-title":"Acta Biomater"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"e2307858","DOI":"10.1002\/advs.202307858","volume":"11","author":"Wang","year":"2024","journal-title":"Adv Sci"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"9689","DOI":"10.2147\/ijn.S473473","volume":"19","author":"Fang","year":"2024","journal-title":"Int J Nanomed"},{"key":"ref66","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.jprot.2018.12.029","volume":"195","author":"Liu","year":"2019","journal-title":"J Proteomics"},{"key":"ref67","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21144848","volume":"21","author":"Charest","year":"2020","journal-title":"Int J Mol Sci"},{"key":"ref68","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1007\/s40199-019-00251-w","volume":"27","author":"Moradi","year":"2019","journal-title":"Daru"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"3705","DOI":"10.1039\/d3na00166k","volume":"5","author":"Gabrielaitis","year":"2023","journal-title":"Nanoscale Adv"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"119320","DOI":"10.1016\/j.ijpharm.2020.119320","volume":"582","author":"Faghfoori","year":"2020","journal-title":"Int J Pharm"},{"key":"ref71","doi-asserted-by":"publisher","first-page":"4321","DOI":"10.1038\/s41467-018-06655-7","volume":"9","author":"Ni","year":"2018","journal-title":"Nat Commun"},{"key":"ref72","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/j.canlet.2020.11.021","volume":"500","author":"DuRoss","year":"2021","journal-title":"Cancer Lett"},{"key":"ref73","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1021\/acs.molpharmaceut.7b00808","volume":"15","author":"Meng","year":"2018","journal-title":"Mol Pharm"},{"key":"ref74","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6528\/ad0c74","volume":"35","author":"Belyaev","year":"2023","journal-title":"Nanotechnology"},{"key":"ref75","doi-asserted-by":"publisher","first-page":"107447","DOI":"10.1016\/j.pharmthera.2019.107447","volume":"206","author":"Vodenkova","year":"2020","journal-title":"Pharmacol Ther"},{"key":"ref76","doi-asserted-by":"publisher","first-page":"3018","DOI":"10.2174\/0113816128274742231103063738","volume":"29","author":"Mahaki","year":"2023","journal-title":"Curr Pharm Des"},{"key":"ref77","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-023-02104-w","volume":"21","author":"Shengyun","year":"2023","journal-title":"J Nanobiotechnol"},{"key":"ref78","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-023-02126-4","volume":"21","author":"Silveira","year":"2023","journal-title":"J Nanobiotechnol"},{"key":"ref79","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajps.2023.100801","volume":"18","author":"Zhang","year":"2023","journal-title":"Asian J Pharm Sci"},{"key":"ref80","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-023-02157-x","volume":"21","author":"Yuan","year":"2023","journal-title":"J Nanobiotechnol"},{"key":"ref81","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2023.122332","volume":"302","author":"Jiaxue","year":"2023","journal-title":"Biomaterials"},{"key":"ref82","doi-asserted-by":"publisher","first-page":"11838","DOI":"10.1021\/acsnano.3c03050","volume":"17","author":"Shenshen","year":"2023","journal-title":"ACS Nano"},{"key":"ref83","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2024.122477","volume":"306","author":"Wang","year":"2024","journal-title":"Biomaterials"},{"key":"ref84","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1021\/acsami.4c13358","volume":"17","author":"Cui","year":"2024","journal-title":"ACS App Mater Interfaces"},{"key":"ref85","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-024-02566-6","volume":"22","author":"Cheng","year":"2024","journal-title":"J Nanobiotechnol"},{"key":"ref86","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2024.102273","volume":"56","author":"Liu","year":"2024","journal-title":"Nano Today"},{"key":"ref87","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2024.154750","volume":"497","author":"Wang","year":"2024","journal-title":"Chem Eng J"},{"key":"ref88","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.nano.2019.02.021","volume":"18","author":"Sanoff","year":"2019","journal-title":"Nanomedicine"},{"key":"ref89","doi-asserted-by":"publisher","first-page":"102369","DOI":"10.1016\/j.nano.2021.102369","volume":"34","author":"Li","year":"2021","journal-title":"Nanomedicine"},{"key":"ref90","doi-asserted-by":"publisher","first-page":"2119","DOI":"10.2147\/ijn.S240083","volume":"15","author":"Yao","year":"2020","journal-title":"Int J Nanomed"},{"key":"ref91","doi-asserted-by":"publisher","first-page":"119394","DOI":"10.1016\/j.ijpharm.2020.119394","volume":"584","author":"Wu","year":"2020","journal-title":"Int J Pharm"},{"key":"ref92","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1080\/10717544.2021.1914777","volume":"28","author":"Du","year":"2021","journal-title":"Drug Deliv"},{"key":"ref93","doi-asserted-by":"publisher","first-page":"106080","DOI":"10.1016\/j.phrs.2022.106080","volume":"176","author":"Li","year":"2022","journal-title":"Pharmacol Res"},{"key":"ref94","doi-asserted-by":"publisher","first-page":"15959","DOI":"10.1021\/acsami.0c21349","volume":"13","author":"Fernandes","year":"2021","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref95","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202300524","volume":"12","author":"Wang","year":"2023","journal-title":"Adv Healthcare Mater"},{"key":"ref96","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2023.101985","volume":"52","author":"Meng","year":"2023","journal-title":"Nano Today"},{"key":"ref97","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202410011","volume":"12","author":"Haiting","year":"2025","journal-title":"Adv Sci"},{"key":"ref98","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2024.122846","volume":"314","author":"Lijun","year":"2025","journal-title":"Biomaterials"},{"key":"ref99","doi-asserted-by":"publisher","DOI":"10.1002\/sstr.202400100","volume":"5","author":"Caiying","year":"2024","journal-title":"Small Struct"},{"key":"ref100","doi-asserted-by":"publisher","first-page":"5165","DOI":"10.1021\/acsnano.4c08828","volume":"19","author":"Yoonhee","year":"2025","journal-title":"ACS Nano"},{"key":"ref101","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1016\/j.jcis.2024.12.228","volume":"683","author":"Chen","year":"2025","journal-title":"J Colloid Interface Sci"},{"key":"ref102","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/j.bioactmat.2025.01.022","volume":"47","author":"Liu","year":"2025","journal-title":"Bioact Mater"},{"key":"ref103","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202300548","volume":"35","author":"Xiaoling","year":"2023","journal-title":"Adv Mater"},{"key":"ref104","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.7150\/thno.100998","volume":"15","author":"Yan","year":"2025","journal-title":"Theranostics"},{"key":"ref105","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2025.101611","volume":"31","author":"Lei","year":"2025","journal-title":"Mater Today Bio"},{"key":"ref106","doi-asserted-by":"publisher","first-page":"e2408086","DOI":"10.1002\/advs.202408086","author":"Wang","year":"2025","journal-title":"Adv Sci"},{"key":"ref107","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.bioactmat.2024.09.022","volume":"43","author":"Xinchen","year":"2025","journal-title":"Bioact Mater"},{"key":"ref108","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-024-02970-y","volume":"22","author":"Peng","year":"2024","journal-title":"J Nanobiotechnol"},{"key":"ref109","doi-asserted-by":"publisher","DOI":"10.1186\/s40824-023-00427-1","volume":"27","author":"Jiang","year":"2023","journal-title":"Biomater Res"},{"key":"ref110","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2024.122530","volume":"307","author":"Baoyi","year":"2024","journal-title":"Biomaterials"},{"key":"ref111","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.mattod.2023.06.024","volume":"68","author":"Jin","year":"2023","journal-title":"Mater Today"},{"key":"ref112","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01491-8","volume":"8","author":"Wang","year":"2023","journal-title":"Signal Transduction Targeted Ther"},{"key":"ref113","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202409875","volume":"21","author":"Cun","year":"2025","journal-title":"Small"},{"key":"ref114","doi-asserted-by":"publisher","first-page":"13481","DOI":"10.1021\/acsami.3c16813","volume":"16","author":"Lin","year":"2024","journal-title":"ACS App Mater Interfaces"},{"key":"ref115","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-024-02515-3","volume":"22","author":"Zhilong","year":"2024","journal-title":"J Nanobiotechnol"},{"key":"ref116","doi-asserted-by":"publisher","first-page":"14164","DOI":"10.1021\/acsami.3c01210","volume":"15","author":"Xiaohui","year":"2023","journal-title":"ACS App Mater Interfaces"},{"key":"ref117","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202407685","volume":"34","author":"Zhu","year":"2024","journal-title":"Adv Funct Mater"},{"key":"ref118","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2025.123233","volume":"320","author":"Shiquan","year":"2025","journal-title":"Biomaterials"},{"key":"ref119","doi-asserted-by":"publisher","DOI":"10.34133\/research.0364","volume":"7","author":"Lei","year":"2024","journal-title":"Research"},{"key":"ref120","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adm9561","volume":"10","author":"Fan","year":"2024","journal-title":"Sci Adv"},{"key":"ref121","doi-asserted-by":"publisher","first-page":"e2400485","DOI":"10.1002\/advs.202400485","volume":"11","author":"Zhang","year":"2024","journal-title":"Adv Sci"},{"key":"ref122","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1186\/s12951-024-02909-3","volume":"22","author":"Li","year":"2024","journal-title":"J Nanobiotechnol"},{"key":"ref123","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.jconrel.2024.03.052","volume":"369","author":"Ding","year":"2024","journal-title":"J Control Release"},{"key":"ref124","doi-asserted-by":"publisher","first-page":"2565","DOI":"10.1016\/j.scib.2024.06.016","volume":"69","author":"Chen","year":"2024","journal-title":"Sci Bull"},{"key":"ref125","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1038\/s41551-019-0423-2","volume":"3","author":"Zheng","year":"2019","journal-title":"Nat Biomed Eng"},{"key":"ref126","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.biomaterials.2019.04.029","volume":"211","author":"Jin","year":"2019","journal-title":"Biomaterials"},{"key":"ref127","doi-asserted-by":"publisher","first-page":"e2203466","DOI":"10.1002\/smll.202203466","volume":"18","author":"Cao","year":"2022","journal-title":"Small"},{"key":"ref128","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1208\/s12249-020-01731-y","volume":"21","author":"Cabeza","year":"2020","journal-title":"AAPS Pharm Sci Tech"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/103746","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/103746","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T12:45:14Z","timestamp":1749473114000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/multifaceted-applications-of-nanomaterials-in-colorectal-cancer-manage-peer-reviewed-fulltext-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":128,"URL":"https:\/\/doi.org\/10.2147\/ijn.s520616","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]}}}