{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T03:55:39Z","timestamp":1793073339667,"version":"4.5.0"},"reference-count":145,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s522028","type":"journal-article","created":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T06:30:16Z","timestamp":1749709816000},"page":"7415-7442","source":"Crossref","is-referenced-by-count":8,"title":["Advanced Therapeutic Approaches Based on Small Extracellular Vehicles (sEVs) For the Regeneration of Spinal Cord Injuries"],"prefix":"10.2147","volume":"Volume 20","author":[{"given":"Anam","family":"Anjum","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvin","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hafiz Bilawal","family":"Hussain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yogeswaran","family":"Lokanathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/S40659-022-00407-0\/FIGURES\/6","volume":"55","author":"Anjum","year":"2022","journal-title":"Biol Res"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/IJMS21207533","volume":"21","author":"Anjum","year":"2020","journal-title":"Int J Mol Sci"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1007\/S44164-024-00070-7","volume":"3","author":"Anjum","year":"2024","journal-title":"In Vitro Models"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/S11910-019-0984-1","volume":"19","author":"Karsy","year":"2019","journal-title":"Curr Neurol Neurosci Rep"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"108552","DOI":"10.1016\/J.CELREP.2020.108552","volume":"33","author":"Hulstaert","year":"2020","journal-title":"Cell Rep"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/J.ACTBIO.2021.07.026","volume":"134","author":"Yu","year":"2021","journal-title":"Acta Biomater"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"8156","DOI":"10.1007\/S12035-024-04082-Y","volume":"61","author":"Chen","year":"2024","journal-title":"Mol Neurobiol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"114784","DOI":"10.1016\/J.EXPNEUROL.2024.114784","volume":"377","author":"Fu","year":"2024","journal-title":"Exp Neurol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1016\/j.ymthe.2019.11.017","volume":"28","author":"Ge","year":"2020","journal-title":"Mol Ther"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1186\/S13578-023-01011-9","volume":"13","author":"Ge","year":"2023","journal-title":"Cell Biosci"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.3390\/BIOMEDICINES12061256","volume":"12","author":"Gu","year":"2024","journal-title":"Biomedicines"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/S12951-023-02255-W","volume":"22","author":"Guan","year":"2024","journal-title":"J Nanobiotechnol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1368630","DOI":"10.3389\/FNCEL.2024.1368630","volume":"18","author":"Izhiman","year":"2024","journal-title":"Front Cell Neurosci"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1453772","DOI":"10.3389\/FNAGI.2024.1453772\/BIBTEX","volume":"16","author":"Li","year":"2024","journal-title":"Front Aging Neurosci"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1186\/S12951-024-02737-5","volume":"22","author":"Nie","year":"2024","journal-title":"J Nanobiotechnol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1016\/J.BBI.2024.07.005","volume":"120","author":"Lei","year":"2024","journal-title":"Brain Behav Immun"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3390\/LIFE13091924","volume":"13","author":"Mavroudis","year":"2023","journal-title":"Life"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"2031","DOI":"10.1007\/S10571-021-01091-6","volume":"42","author":"Xu","year":"2022","journal-title":"Cell Mol Neurobiol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/J.JOT.2024.09.007","volume":"49","author":"Chen","year":"2024","journal-title":"J Orthop Transl"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"332","DOI":"10.3934\/NEUROSCIENCE.2023026","volume":"10","author":"Akbari-Gharalari","year":"2023","journal-title":"AIMS Neurosci"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1016\/J.BIOACTMAT.2023.11.013","volume":"33","author":"Qin","year":"2024","journal-title":"Bioact Mater"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/J.MTBIO.2024.101250","volume":"28","author":"Wang","year":"2024","journal-title":"Mater Today Bio"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/J.LFS.2024.123014","volume":"356","author":"Wang","year":"2024","journal-title":"Life Sci"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"3022","DOI":"10.1021\/ACSCHEMNEURO.4C00224","volume":"15","author":"Zhou","year":"2024","journal-title":"ACS Chem Neurosci"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.3389\/FPHAR.2024.1419390","volume":"15","author":"Rao","year":"2024","journal-title":"Front Pharmacol"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.3389\/FNCEL.2022.943506","volume":"16","author":"Saquel","year":"2022","journal-title":"Front Cell Neurosci"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.1038\/S41401-019-0338-1","volume":"41","author":"Li","year":"2020","journal-title":"Acta Pharmacol Sin"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"3186","DOI":"10.3390\/BIOMEDICINES10123186","volume":"10","author":"Akram","year":"2022","journal-title":"Biomedicines"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/J.JCONREL.2024.02.019","volume":"368","author":"Liu","year":"2024","journal-title":"J Control Release"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.3389\/FNCEL.2024.1427525","volume":"18","author":"Salehpour","year":"2024","journal-title":"Front Cell Neurosci"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1007\/S11033-023-08972-7","volume":"51","author":"Soleimani","year":"2024","journal-title":"Mol Biol Rep"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"2120","DOI":"10.1007\/S11064-024-04166-0","volume":"49","author":"Zhu","year":"2024","journal-title":"Neurochem Res"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1186\/S13018-024-04651-W","volume":"19","author":"Luan","year":"2024","journal-title":"J Orthopaedic Surg Res"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1186\/S13287-023-03614-Y","volume":"15","author":"Yu","year":"2024","journal-title":"Stem Cell Res Ther"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"1284","DOI":"10.22038\/IJBMS.2024.76532.16576","volume":"27","author":"Zhou","year":"2024","journal-title":"Iran J Basic Med Sci"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1016\/J.NEULET.2020.135399","volume":"739","author":"Zhang","year":"2020","journal-title":"Neurosci lett"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1007\/S12035-024-04056-0","volume":"61","author":"Wu","year":"2024","journal-title":"Mol Neurobiol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.1007\/S12035-024-04490-0","volume":"62","author":"An","year":"2024","journal-title":"Mol Neurobiol"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"1536","DOI":"10.1007\/S10753-020-01230-Z","volume":"43","author":"Shao","year":"2020","journal-title":"Inflammation"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1186\/S13018-023-04523-9","volume":"19","author":"Yang","year":"2024","journal-title":"J Orthopaedic Surg Res"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/S13287-021-02282-0","volume":"12","author":"Chen","year":"2021","journal-title":"Stem Cell Res Ther"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"116836","DOI":"10.1016\/J.BIOPHA.2024.116836","volume":"176","author":"Ebrahim","year":"2024","journal-title":"Biomed Pharmacother"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"1612","DOI":"10.1177\/09603271211003311","volume":"40","author":"Fan","year":"2021","journal-title":"Hum Exp Toxicol"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1186\/S13287-021-02148-5","volume":"12","author":"Wang","year":"2021","journal-title":"Stem Cell Res Ther"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"725573","DOI":"10.3389\/FNCEL.2021.725573","volume":"15","author":"Li","year":"2021","journal-title":"Front Cell Neurosci"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1177\/1535370219895491","volume":"245","author":"Zhong","year":"2020","journal-title":"Exp Biol Med"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"1078761","DOI":"10.3389\/FPHAR.2022.1078761","volume":"13","author":"Li","year":"2023","journal-title":"Front Pharmacol"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.3390\/IJMS22126375","volume":"22","author":"Terriaca","year":"2021","journal-title":"Int J Mol Sci"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"16","DOI":"10.3389\/FNCEL.2022.882306","author":"Yang","year":"2022","journal-title":"Front Cell Neurosci"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.3389\/FCELL.2021.772205","volume":"9","author":"Sheng","year":"2021","journal-title":"Front Cell Develop Biol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.1007\/S11064-022-03545-9","volume":"47","author":"Kang","year":"2022","journal-title":"Neurochem Res"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.3390\/BIOMEDICINES10030678","volume":"10","author":"Sung","year":"2022","journal-title":"Biomedicines"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1186\/S12951-022-01273-4","volume":"20","author":"Liu","year":"2022","journal-title":"J Nanobiotechnol"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1186\/S13287-021-02248-2","volume":"12","author":"Zhou","year":"2021","journal-title":"Stem Cell Res Ther"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"8100298","DOI":"10.1155\/2021\/8100298","volume":"2021","author":"Chen","year":"2021","journal-title":"J Immunol Res"},{"key":"ref56","first-page":"411","volume":"22","author":"Zhang","year":"2022","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1186\/S12974-021-02215-X","volume":"18","author":"Pan","year":"2021","journal-title":"J Neuroinflammation"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1007\/S10529-021-03198-8","volume":"44","author":"Pan","year":"2022","journal-title":"Biotechnol Lett"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1016\/J.ACTBIO.2021.09.026","volume":"136","author":"Luo","year":"2021","journal-title":"Acta Biomater"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1186\/S12951-021-01123-9","volume":"19","author":"Zhang","year":"2021","journal-title":"J Nanobiotechnol"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"1695087","DOI":"10.1155\/2021\/1695087","volume":"2021","author":"Peng","year":"2021","journal-title":"Oxid Med Cell Longev"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"7591","DOI":"10.1039\/D0TB01499K","volume":"8","author":"Peng","year":"2020","journal-title":"J Mat Chem B"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"738442","DOI":"10.3389\/FNINS.2021.738442","volume":"15","author":"Huo","year":"2021","journal-title":"Front Neurosci"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"4502","DOI":"10.1007\/S12035-023-03341-8","volume":"60","author":"Xu","year":"2023","journal-title":"Mol Neurobiol"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"568889","DOI":"10.3389\/fcell.2020.568889","volume":"8","author":"Gharbi","year":"2020","journal-title":"Front Cell Develop Biol"},{"key":"ref66","doi-asserted-by":"publisher","DOI":"10.1523\/ENEURO.0336-23.2024","volume":"11","author":"Qian","year":"2024","journal-title":"ENeuro"},{"key":"ref67","doi-asserted-by":"publisher","DOI":"10.1186\/S12951-022-01724-Y","volume":"20","author":"Xiong","year":"2022","journal-title":"J Nanobiotechnol"},{"key":"ref68","doi-asserted-by":"publisher","DOI":"10.1080\/20013078.2018.1535750","volume":"7","author":"Th\u00e9ry","year":"2018","journal-title":"J Extracell Vesicles"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"3357","DOI":"10.2147\/IJN.S310357","volume":"16","author":"Gurunathan","year":"2021","journal-title":"Int J Nanomed"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/IJMS21207568","volume":"21","author":"Jankovi\u010dov\u00e1","year":"2020","journal-title":"Int J Mol Sci"},{"key":"ref71","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1186\/S12943-022-01671-0","volume":"21","author":"Han","year":"2022","journal-title":"Mol Cancer"},{"key":"ref72","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/S10571-016-0366-Z","volume":"36","author":"Abels","year":"2016","journal-title":"Cell Mol Neurobiol"},{"key":"ref73","doi-asserted-by":"publisher","first-page":"1198044","DOI":"10.3389\/FMOLB.2023.1198044","volume":"10","author":"Ghadami","year":"2023","journal-title":"Front Mol Biosci"},{"key":"ref74","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/J.CELLIMM.2014.03.016","volume":"289","author":"Sobo-Vujanovic","year":"2014","journal-title":"Cell Immunol"},{"key":"ref75","doi-asserted-by":"publisher","DOI":"10.3390\/PHARMACEUTICS15020598","volume":"15","author":"Lu","year":"2023","journal-title":"Pharmaceutics"},{"key":"ref76","doi-asserted-by":"publisher","DOI":"10.3390\/CELLS12101416","volume":"12","author":"Zeng","year":"2023","journal-title":"Cells"},{"key":"ref77","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1691\/PH.2021.0128","volume":"76","author":"Xi","year":"2021","journal-title":"Die Pharmazie"},{"key":"ref78","doi-asserted-by":"publisher","DOI":"10.1093\/RB\/RBAE081","volume":"11","author":"Zhao","year":"2024","journal-title":"Regen Biomater"},{"key":"ref79","doi-asserted-by":"publisher","first-page":"2361165","DOI":"10.1080\/10717544.2024.2361165","volume":"31","author":"Chen","year":"2024","journal-title":"Drug Delivery"},{"key":"ref80","doi-asserted-by":"publisher","first-page":"1481","DOI":"10.3390\/NANO11061481","volume":"11","author":"Butreddy","year":"2021","journal-title":"Nanomaterials"},{"key":"ref81","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/J.ACTBIO.2021.03.018","volume":"126","author":"Gao","year":"2021","journal-title":"Acta Biomater"},{"key":"ref82","doi-asserted-by":"publisher","first-page":"7137","DOI":"10.2147\/IJN.S464249","volume":"19","author":"Bahadorani","year":"2024","journal-title":"Int J Nanomed"},{"key":"ref83","doi-asserted-by":"publisher","first-page":"1010","DOI":"10.3390\/POLYM14051010","volume":"14","author":"Nunes","year":"2022","journal-title":"Polymers"},{"key":"ref84","doi-asserted-by":"publisher","DOI":"10.1002\/JEV2.12137","volume":"10","author":"Nakazaki","year":"2021","journal-title":"J Extracell Vesicles"},{"key":"ref85","doi-asserted-by":"publisher","first-page":"102040","DOI":"10.1016\/J.OMTN.2023.102040","volume":"34","author":"Lu","year":"2023","journal-title":"Mol Ther Nucleic Acids"},{"key":"ref86","doi-asserted-by":"publisher","first-page":"1309172","DOI":"10.3389\/FNINS.2023.1309172","volume":"17","author":"Nazerian","year":"2023","journal-title":"Front Neurosci"},{"key":"ref87","doi-asserted-by":"publisher","first-page":"100044","DOI":"10.1016\/J.VESIC.2024.100044","volume":"3","author":"Singh","year":"2024","journal-title":"Extracell Vesicle"},{"key":"ref88","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1016\/J.BIOACTMAT.2022.07.002","volume":"25","author":"Ran","year":"2022","journal-title":"Bioact Mater"},{"key":"ref89","doi-asserted-by":"publisher","DOI":"10.3389\/FNMOL.2024.1448777","volume":"17","author":"Ye","year":"2024","journal-title":"Front Mol Neurosci"},{"key":"ref90","doi-asserted-by":"publisher","first-page":"6048","DOI":"10.3390\/IJMS21176048","volume":"21","author":"Villata","year":"2020","journal-title":"Int J Mol Sci"},{"key":"ref91","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202101151","volume":"11","author":"Mehanny","year":"2022","journal-title":"Adv Healthcare Mater"},{"key":"ref92","doi-asserted-by":"publisher","first-page":"240","DOI":"10.3390\/CELLS10020240","volume":"10","author":"Jarrige","year":"2021","journal-title":"Cells"},{"key":"ref93","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41392-022-00932-0","volume":"7","author":"Han","year":"2022","journal-title":"Signal Transduct Target Ther"},{"key":"ref94","unstructured":"Salazar Puerta AI. Engineering extracellular vesicles for therapeutic applications. 2022."},{"key":"ref95","doi-asserted-by":"publisher","DOI":"10.1002\/JEV2.12140","volume":"10","author":"T\u00f3th","year":"2021","journal-title":"J Extracell Vesicles"},{"key":"ref96","doi-asserted-by":"publisher","DOI":"10.3389\/FNUT.2022.838543","volume":"9","author":"Zhou","year":"2022","journal-title":"Front Nutr"},{"key":"ref97","doi-asserted-by":"publisher","first-page":"1060850","DOI":"10.3389\/FCELL.2022.1060850\/BIBTEX","volume":"10","author":"Ortega","year":"2022","journal-title":"Front cell develop biol"},{"key":"ref98","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/S12951-023-02173-X\/FIGURES\/5","volume":"21","author":"Zhang","year":"2023","journal-title":"J Nanobiotechnol"},{"key":"ref99","doi-asserted-by":"publisher","first-page":"814","DOI":"10.1038\/s43587-024-00612-4","volume":"4","author":"Chen","year":"2024","journal-title":"Nature Aging"},{"key":"ref100","doi-asserted-by":"publisher","first-page":"2403199","DOI":"10.1002\/ADMA.202403199","volume":"36","author":"Xia","year":"2024","journal-title":"Adv Mater"},{"key":"ref101","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1016\/j.bbrc.2019.02.005","volume":"510","author":"Li","year":"2019","journal-title":"Biochem Biophys Res Commun"},{"key":"ref102","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.brainres.2019.01.037","volume":"1712","author":"Tatebayashi","year":"2019","journal-title":"Brain Res"},{"key":"ref103","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1007\/s11011-020-00543-0","volume":"35","author":"Akhlaghpasand","year":"2020","journal-title":"Metab Brain Dis"},{"key":"ref104","doi-asserted-by":"publisher","first-page":"107576","DOI":"10.1016\/J.ANIREPROSCI.2024.107576","volume":"270","author":"Wang","year":"2024","journal-title":"Anim Reprod Sci"},{"key":"ref105","doi-asserted-by":"publisher","first-page":"22258","DOI":"10.1074\/JBC.M114.588046","volume":"289","author":"Tian","year":"2014","journal-title":"J Biol Chem"},{"key":"ref106","doi-asserted-by":"publisher","first-page":"13460","DOI":"10.3390\/IJMS252413460","volume":"25","author":"Nakazaki","year":"2024","journal-title":"Int J Mol Sci"},{"key":"ref107","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/S12987-018-0104-7","volume":"15","author":"Ramirez","year":"2018","journal-title":"Fluids Barriers CNS"},{"key":"ref108","unstructured":"Nasiri Kenari A. Defining extracellular vesicle mimetic nanovesicles protein and RNA composition, and its therapeutic potential. 2022. doi:10.26181\/21114490.V1."},{"key":"ref109","doi-asserted-by":"publisher","first-page":"e6","DOI":"10.1017\/S0033583524000027","volume":"57","author":"Amiri","year":"2024","journal-title":"Q Rev Biophys"},{"key":"ref110","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1002\/SCTM.20-0376","volume":"10","author":"Cardoso","year":"2021","journal-title":"Stem Cells Transl Med"},{"key":"ref111","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1016\/J.JCIS.2024.04.074","volume":"667","author":"Salerno","year":"2024","journal-title":"J Colloid Interface Sci"},{"key":"ref112","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.18609\/CGTI.2021.140","volume":"7","author":"Tacheny","year":"2021","journal-title":"Cell Gene Ther Insights"},{"key":"ref113","doi-asserted-by":"publisher","first-page":"101668","DOI":"10.1016\/J.BBREP.2024.101668","volume":"38","author":"Ansari","year":"2024","journal-title":"Biochem Biophys Rep"},{"key":"ref114","doi-asserted-by":"publisher","first-page":"12266","DOI":"10.1002\/JEV2.12266","volume":"11","author":"Visan","year":"2022","journal-title":"J Extracell Vesicles"},{"key":"ref115","doi-asserted-by":"publisher","first-page":"5803","DOI":"10.1039\/D4NA00501E","volume":"6","author":"Palakurthi","year":"2024","journal-title":"Nanoscale Adv"},{"key":"ref116","doi-asserted-by":"publisher","first-page":"7617","DOI":"10.1111\/JCMM.14635","volume":"23","author":"Xu","year":"2019","journal-title":"J Cell Mol Med"},{"key":"ref117","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1002\/STEM.2730","volume":"36","author":"Harting","year":"2018","journal-title":"Stem Cells"},{"key":"ref118","doi-asserted-by":"publisher","first-page":"119942","DOI":"10.1016\/J.BIOMATERIALS.2020.119942","volume":"243","author":"Kim","year":"2020","journal-title":"Biomaterials"},{"key":"ref119","doi-asserted-by":"publisher","first-page":"7979","DOI":"10.2147\/IJN.S275650","volume":"15","author":"Wu","year":"2020","journal-title":"Int J Nanomed"},{"key":"ref120","doi-asserted-by":"publisher","first-page":"6911","DOI":"10.1096\/FJ.201800597R","volume":"32","author":"Jia","year":"2018","journal-title":"FASEB J"},{"key":"ref121","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1002\/BTM2.10065","volume":"2","author":"Patel","year":"2017","journal-title":"Bioeng Transl Med"},{"key":"ref122","doi-asserted-by":"publisher","first-page":"1803","DOI":"10.1039\/D1BM01722E","volume":"10","author":"Mu","year":"2022","journal-title":"Biomater Sci"},{"key":"ref123","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1002\/BIT.27606","volume":"118","author":"Abdollahi","year":"2021","journal-title":"Biotechnol Bioeng"},{"key":"ref124","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1007\/S10565-019-09504-5","volume":"36","author":"Yan","year":"2020","journal-title":"Cell Biol Toxicol"},{"key":"ref125","doi-asserted-by":"publisher","first-page":"553444","DOI":"10.3389\/FCELL.2020.553444","volume":"8","author":"De Almeida Fuzeta","year":"2020","journal-title":"Front Cell Develop Biol"},{"key":"ref126","doi-asserted-by":"publisher","first-page":"3239","DOI":"10.1111\/CNS.14256","volume":"29","author":"Ye","year":"2023","journal-title":"CNS Neurosci Ther"},{"key":"ref127","doi-asserted-by":"publisher","first-page":"845","DOI":"10.3389\/FNINS.2018.00845","volume":"12","author":"Li","year":"2018","journal-title":"Front Neurosci"},{"key":"ref128","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/J.BRAINRESBULL.2021.02.015","volume":"170","author":"Chang","year":"2021","journal-title":"Brain Res Bull"},{"key":"ref129","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1089\/NEU.2021.0290","volume":"39","author":"Liang","year":"2022","journal-title":"J Neurotrauma"},{"key":"ref130","doi-asserted-by":"publisher","DOI":"10.1016\/J.BIOCEL.2021.105921","volume":"132","author":"Yin","year":"2021","journal-title":"Int J Biochem Cell Biol"},{"key":"ref131","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1089\/NEU.2021.0464","volume":"39","author":"Zhou","year":"2022","journal-title":"J Neurotrauma"},{"key":"ref132","doi-asserted-by":"publisher","first-page":"703989","DOI":"10.3389\/FCELL.2021.703989","volume":"9","author":"Feng","year":"2021","journal-title":"Front Cell Develop Biol"},{"key":"ref133","doi-asserted-by":"publisher","first-page":"100163","DOI":"10.1016\/J.MEDIDD.2023.100163","volume":"20","author":"Yadav","year":"2023","journal-title":"Med Drug Discov"},{"key":"ref134","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1021\/ACS.NANOLETT.8B02689","volume":"19","author":"Li","year":"2019","journal-title":"Nano Lett"},{"key":"ref135","doi-asserted-by":"publisher","first-page":"585","DOI":"10.2147\/IJN.S154458","volume":"13","author":"Liang","year":"2018","journal-title":"Int J Nanomed"},{"key":"ref136","doi-asserted-by":"publisher","first-page":"865682","DOI":"10.3389\/FBIOE.2022.865682\/BIBTEX","volume":"10","author":"Wang","year":"2022","journal-title":"Front Bioeng Biotechnol"},{"key":"ref137","doi-asserted-by":"publisher","first-page":"1891","DOI":"10.1016\/J.BBAMCR.2018.09.008","volume":"1865","author":"Nizamudeen","year":"2018","journal-title":"Biochim Biophys Acta Mol Cell Res"},{"key":"ref138","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/J.BBRC.2022.08.025","volume":"627","author":"Okada-Tsuchioka","year":"2022","journal-title":"Biochem Biophys Res Commun"},{"key":"ref139","doi-asserted-by":"publisher","first-page":"943712","DOI":"10.3389\/FBIOE.2022.943712","volume":"10","author":"Liu","year":"2022","journal-title":"Front Bioeng Biotechnol"},{"key":"ref140","doi-asserted-by":"publisher","first-page":"113961","DOI":"10.1016\/J.ADDR.2021.113961","volume":"178","author":"Gupta","year":"2021","journal-title":"Adv Drug Delivery Rev"},{"key":"ref141","doi-asserted-by":"publisher","first-page":"e12085","DOI":"10.1002\/JEV2.12085","volume":"10","author":"Kang","year":"2021","journal-title":"J Extracell Vesicles"},{"key":"ref142","doi-asserted-by":"publisher","first-page":"100029","DOI":"10.1016\/J.VESIC.2023.100029","volume":"2","author":"Cheng","year":"2023","journal-title":"Extracellular Vesicle"},{"key":"ref143","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1161\/CIRCRESAHA.123.323054","volume":"135","author":"Rai","year":"2024","journal-title":"Circ Res"},{"key":"ref144","doi-asserted-by":"publisher","first-page":"e13904","DOI":"10.1111\/CTS.13904","volume":"17","author":"Wang","year":"2024","journal-title":"Clin Transl Sci"},{"key":"ref145","doi-asserted-by":"publisher","first-page":"1178","DOI":"10.3390\/BIOLOGY12091178\/S1","volume":"12","author":"Kumar","year":"2023","journal-title":"Biology"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/103859","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/103859","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T06:30:21Z","timestamp":1749709821000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/advanced-therapeutic-approaches-based-on-small-extracellular-vehicles--peer-reviewed-fulltext-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":145,"URL":"https:\/\/doi.org\/10.2147\/ijn.s522028","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]}}}