{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T01:59:51Z","timestamp":1788400791512,"version":"build-2803163510"},"reference-count":46,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s527094","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T09:15:14Z","timestamp":1758705314000},"page":"11803-11821","source":"Crossref","is-referenced-by-count":2,"title":["Engineering Study on Targeted Therapy of Osteosarcoma Using Tripterine Loaded Polydopamine Mesoporous Microspheres Combined with Photothermal Therapy"],"prefix":"10.2147","volume":"Volume 20","author":[{"given":"Molin","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufei","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7671-7687","authenticated-orcid":true,"given":"Hui","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yalan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuefeng","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"100635","DOI":"10.1016\/j.jbo.2024.100635","volume":"48","author":"Barzegari","year":"2024","journal-title":"J Bone Oncol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1038\/s41413-023-00260-1","volume":"11","author":"Huang","year":"2023","journal-title":"Bone Res"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"113770","DOI":"10.1016\/j.colsurfb.2024.113770","volume":"235","author":"Lin","year":"2024","journal-title":"Colloids Surf B"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/s43046-021-00059-3","volume":"33","author":"Desai","year":"2021","journal-title":"J Egypt Math Nat Cancer Ins"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1039\/D0NP00054J","volume":"38","author":"Tong","year":"2021","journal-title":"Nat Product Rep"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"673209","DOI":"10.3389\/fphar.2021.673209","volume":"12","author":"Wagh","year":"2021","journal-title":"Front Pharmacol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1871","DOI":"10.3390\/antiox10121871","volume":"10","author":"Mart\u00edn-Ram\u00edrez","year":"2021","journal-title":"Antioxidants"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"16887","DOI":"10.18632\/aging.103590","volume":"12","author":"Li","year":"2020","journal-title":"Aging"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"6355","DOI":"10.1039\/D1BM00639H","volume":"9","author":"Guo","year":"2021","journal-title":"Biomater Sci"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"114882","DOI":"10.1016\/j.biopha.2023.114882","volume":"163","author":"Wang","year":"2023","journal-title":"Biomed Pharmacother"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.jcis.2022.12.162","volume":"636","author":"Liu","year":"2023","journal-title":"J Colloid Interface Sci"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"e2410427","DOI":"10.1002\/advs.202410427","volume":"12","author":"Luo","year":"2025","journal-title":"Adv Sci"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"110719","DOI":"10.1016\/j.colsurfb.2019.110719","volume":"186","author":"El Yakhlifi","year":"2020","journal-title":"Colloids Surf B"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"10875","DOI":"10.1039\/D0CC02888F","volume":"56","author":"Jing","year":"2020","journal-title":"Chem Commun"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"e2000228","DOI":"10.1002\/mabi.202000228","volume":"20","author":"Zheng","year":"2020","journal-title":"Macromol biosci"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"126443","DOI":"10.1016\/j.cej.2020.126443","volume":"404","author":"Zhan","year":"2021","journal-title":"Chem Eng J"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1186\/s12951-022-01643-y","volume":"20","author":"Li","year":"2022","journal-title":"J Nanobiotechnol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.actbio.2022.03.023","volume":"144","author":"Liu","year":"2022","journal-title":"Acta Biomater"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"16793","DOI":"10.1021\/acsami.7b01540","volume":"9","author":"Li","year":"2017","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"11306","DOI":"10.1021\/jacs.6b06558","volume":"138","author":"Guan","year":"2016","journal-title":"J Am Chem Soc"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"8647","DOI":"10.2147\/IJN.S218632","volume":"14","author":"Zhang","year":"2019","journal-title":"Int J Nanomed"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.devcel.2006.11.003","volume":"12","author":"Tu","year":"2007","journal-title":"Dev Cell"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1016\/j.bbagen.2016.01.025","volume":"1860","author":"Borriello","year":"2016","journal-title":"BBA"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1021\/bm101281b","volume":"12","author":"Ju","year":"2011","journal-title":"Biomacromolecules"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1903129","DOI":"10.1002\/advs.201903129","volume":"7","author":"Liu","year":"2020","journal-title":"Adv Sci"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"15484","DOI":"10.3390\/ijms242015484","volume":"24","author":"Gallo","year":"2023","journal-title":"Int J Mol Sci"},{"key":"ref27","first-page":"448","author":"Zeng","year":"2022","journal-title":"Chem Eng J"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"7707","DOI":"10.1039\/D3CS00356F","volume":"52","author":"Hao","year":"2023","journal-title":"Chem Soc Rev"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1849","DOI":"10.3390\/cells9081849","volume":"9","author":"Fukai","year":"2020","journal-title":"Cells"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"10954","DOI":"10.1039\/D0TB01939A","volume":"8","author":"Fang","year":"2020","journal-title":"J Mat Chem B"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"558741","DOI":"10.3389\/fphar.2020.558741","volume":"11","author":"Shi","year":"2020","journal-title":"Front Pharmacol"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1947","DOI":"10.1021\/ja511560b","volume":"137","author":"Wang","year":"2015","journal-title":"J Am Chem Soc"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"105235","DOI":"10.1016\/j.ejps.2020.105235","volume":"145","author":"Alamzadeh","year":"2020","journal-title":"Eur J Pharm Sci"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1039\/D1TB02280F","volume":"10","author":"Macchi","year":"2022","journal-title":"J Mat Chem B"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"121802","DOI":"10.1016\/j.lfs.2023.121802","volume":"326","author":"Varaganti","year":"2023","journal-title":"Life Sci"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.msec.2017.03.027","volume":"76","author":"Ai","year":"2017","journal-title":"Mater Sci Eng"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"112911","DOI":"10.1016\/j.colsurfb.2022.112911","volume":"220","author":"Amiryaghoubi","year":"2022","journal-title":"Colloids Surf B"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"109731","DOI":"10.1016\/j.cbi.2021.109731","volume":"351","author":"Karimian","year":"2022","journal-title":"Chem Biol Interact"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1016\/j.trecan.2017.10.006","volume":"3","author":"Burke","year":"2017","journal-title":"Trends Cancer"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1016\/j.bbrc.2018.11.014","volume":"507","author":"Hong","year":"2018","journal-title":"Biochem Biophys Res Commun"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1016\/j.bbrc.2012.05.143","volume":"423","author":"Huang","year":"2012","journal-title":"Biochem Biophys Res Commun"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"1040","DOI":"10.3390\/molecules28031040","volume":"28","author":"Zhang","year":"2023","journal-title":"Molecules"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202302712","volume":"13","author":"Berger","year":"2024","journal-title":"Adv Healthcare Mater"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1007\/s13233-021-9026-3","volume":"29","author":"Lee","year":"2021","journal-title":"Macromol Res"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.mattod.2024.01.004","volume":"73","author":"Zhang","year":"2024","journal-title":"Mater Today"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"3140","DOI":"10.1021\/acs.iecr.3c04310","volume":"63","author":"Li","year":"2024","journal-title":"Ind Eng Chem Res"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/107263","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/107263","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T09:15:15Z","timestamp":1758705315000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/engineering-study-on-targeted-therapy-of-osteosarcoma-using-tripterine-peer-reviewed-fulltext-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":46,"URL":"https:\/\/doi.org\/10.2147\/ijn.s527094","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9]]}}}