{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T21:43:13Z","timestamp":1792532593306,"version":"4.5.0"},"reference-count":79,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s596646","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T16:00:11Z","timestamp":1776268811000},"page":"1-16","source":"Crossref","is-referenced-by-count":7,"title":["Nanomedicine-Integrated Phototherapy for Cancer Theranostics: A Systematic Review of Photoresponsive Materials, Mechanisms, and Clinical Translation"],"prefix":"10.2147","volume":"Volume 21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4149-3978","authenticated-orcid":true,"given":"Fahad","family":"Alsaikhan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6252-2261","authenticated-orcid":true,"given":"Turki","family":"Al-Saikhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yara","family":"Alsaikhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,4]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1016\/S0140-6736(16)31012-1","volume":"388","author":"Wang","year":"2016","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1016\/j.semcancer.2021.05.018","volume":"86","author":"Saeed","year":"2022","journal-title":"Semin Cancer Biol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"8606","DOI":"10.1039\/D2RA07863E","volume":"13","author":"Nirmala","year":"2023","journal-title":"RSC Adv"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"8036","DOI":"10.2174\/0929867328666210420101605","volume":"28","author":"Shoaib","year":"2021","journal-title":"Curr Med Chem"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"723","DOI":"10.3390\/pharmaceutics13050723","volume":"13","author":"Bhushan","year":"2021","journal-title":"Pharmaceutics"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"2068","DOI":"10.1021\/acsnano.0c09115","volume":"15","author":"Cook","year":"2021","journal-title":"ACS Nano"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"597634","DOI":"10.3389\/fmolb.2020.597634","volume":"7","author":"Mohapatra","year":"2021","journal-title":"Front Mol Biosci"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.pdpdt.2010.12.001","volume":"8","author":"Paszko","year":"2011","journal-title":"Photodiagn Photodyn Ther"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"113","DOI":"10.3390\/biomedicines9020113","volume":"9","author":"Yoo","year":"2021","journal-title":"Biomedicines"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1615\/CritRevTherDrugCarrierSyst.2015011645","volume":"32","author":"Garg","year":"2015","journal-title":"Crit Rev Ther Drug Carrier Syst"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1433","DOI":"10.2147\/IJN.S405020","volume":"18","author":"He","year":"2023","journal-title":"Int J Nanomed"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1016\/j.bioactmat.2022.11.013","volume":"23","author":"Li","year":"2023","journal-title":"Bioact Mater"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1879","DOI":"10.7150\/thno.67300","volume":"12","author":"Ji","year":"2022","journal-title":"Theranostics"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.canlet.2018.10.044","volume":"442","author":"Li","year":"2019","journal-title":"Cancer Lett"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"686303","DOI":"10.3389\/fchem.2021.686303","volume":"9","author":"Gunaydin","year":"2021","journal-title":"Front Chem"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"2793","DOI":"10.3390\/cancers12102793","volume":"12","author":"Alsaab","year":"2020","journal-title":"Cancers"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1186\/s12951-021-00903-7","volume":"19","author":"Liu","year":"2021","journal-title":"J Nanobiotechnology"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"571","DOI":"10.3390\/jpm11060571","volume":"11","author":"Subhan","year":"2021","journal-title":"J Pers Med"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.addr.2020.06.005","volume":"157","author":"Fang","year":"2020","journal-title":"Adv Drug Deliv Rev"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"2002797","DOI":"10.1002\/advs.202002797","volume":"8","author":"Zhang","year":"2021","journal-title":"Adv Sci"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"22594","DOI":"10.1021\/acsanm.3c04487","volume":"6","author":"Wang","year":"2023","journal-title":"ACS Appl Nano Mater"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1038\/s41568-022-00496-9","volume":"22","author":"Bhatia","year":"2022","journal-title":"Nat Rev Cancer"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"7","DOI":"10.5946\/ce.2013.46.1.7","volume":"46","author":"Yoon","year":"2013","journal-title":"Clin Endosc"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"2480","DOI":"10.3390\/ijms21072480","volume":"21","author":"Bai","year":"2020","journal-title":"Int J Mol Sci"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"2891","DOI":"10.1021\/nn401196a","volume":"7","author":"Cha","year":"2013","journal-title":"ACS Nano"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1007\/s11095-010-0318-0","volume":"28","author":"Bhattacharyya","year":"2011","journal-title":"Pharm Res"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.redox.2017.11.018","volume":"15","author":"Tabish","year":"2018","journal-title":"Redox Biol"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1902409","DOI":"10.1002\/adma.201902409","volume":"31","author":"He","year":"2019","journal-title":"Adv Mater"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.semcancer.2019.11.002","volume":"69","author":"Raj","year":"2021","journal-title":"Semin Cancer Biol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1016\/j.nano.2016.11.005","volume":"13","author":"Duong","year":"2017","journal-title":"Nanomedicine"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.1021\/ar200106e","volume":"44","author":"Jokerst","year":"2011","journal-title":"Acc Chem Res"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1805875","DOI":"10.1002\/adma.201805875","volume":"31","author":"Fu","year":"2019","journal-title":"Adv Mater"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"6597","DOI":"10.1039\/C6CS00271D","volume":"45","author":"Zhou","year":"2016","journal-title":"Chem Soc Rev"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"250","DOI":"10.3322\/caac.20114","volume":"61","author":"Agostinis","year":"2011","journal-title":"CA Cancer J Clin"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"4881","DOI":"10.1021\/acs.chemrev.8b00626","volume":"119","author":"Yang","year":"2019","journal-title":"Chem Rev"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"2740","DOI":"10.1039\/c1cs15237h","volume":"41","author":"Dreaden","year":"2012","journal-title":"Chem Soc Rev"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"167","DOI":"10.3389\/fchem.2019.00167","volume":"7","author":"Vines","year":"2019","journal-title":"Front Chem"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"13","DOI":"10.3390\/polym9010013","volume":"9","author":"Hwang","year":"2017","journal-title":"Polymers"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"115070","DOI":"10.1016\/j.biopha.2023.115070","volume":"165","author":"Qi","year":"2023","journal-title":"Biomed Pharmacother"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"112032","DOI":"10.1016\/j.inoche.2024.112032","volume":"161","author":"Karami","year":"2024","journal-title":"Inorg Chem Commun"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"8669","DOI":"10.1039\/d0cs00461h","volume":"50","author":"Wang","year":"2021","journal-title":"Chem Soc Rev"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1039\/C7BM01020F","volume":"6","author":"Jiao","year":"2018","journal-title":"Biomater Sci"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"128844","DOI":"10.1016\/j.cej.2021.128844","volume":"417","author":"Li","year":"2021","journal-title":"Chem Eng J"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"5086","DOI":"10.1039\/D1CS00056J","volume":"50","author":"Zheng","year":"2021","journal-title":"Chem Soc Rev"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"1900848","DOI":"10.1002\/advs.201900848","volume":"6","author":"Cai","year":"2019","journal-title":"Adv Sci"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"3651","DOI":"10.1021\/nn1035262","volume":"5","author":"Xiao","year":"2011","journal-title":"ACS Nano"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"6038","DOI":"10.3390\/molecules28166038","volume":"28","author":"Xie","year":"2023","journal-title":"Molecules"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1002\/asia.202001202","volume":"16","author":"Sarfraz","year":"2021","journal-title":"Chem Asian J"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"18590","DOI":"10.1073\/pnas.1906929116","volume":"116","author":"Rastinehad","year":"2019","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1002\/smll.201000134","volume":"7","author":"Kennedy","year":"2011","journal-title":"Small"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"434","DOI":"10.5281\/zenodo.15010913","volume":"9","author":"Alkac","year":"2025","journal-title":"ISPEC J Agric Sci"},{"key":"ref52","first-page":"704","volume":"9","author":"Oguz","year":"2025","journal-title":"ISPEC J Agric Sci"},{"key":"ref53","first-page":"1182","volume":"9","author":"Alan","year":"2025","journal-title":"ISPEC J Agric Sci"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1159\/000362416","volume":"24","author":"Benov","year":"2014","journal-title":"Med Princ Pract"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/s12094-012-0766-6","volume":"14","author":"Egusquiaguirre","year":"2012","journal-title":"Clin Transl Oncol"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"1900499","DOI":"10.1002\/adma.201900499","volume":"31","author":"Liu","year":"2019","journal-title":"Adv Mater"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"2103978","DOI":"10.1002\/adma.202103978","volume":"33","author":"Wan","year":"2021","journal-title":"Adv Mater"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"6488","DOI":"10.1039\/C6CS00616G","volume":"45","author":"Fan","year":"2016","journal-title":"Chem Soc Rev"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"6608","DOI":"10.3390\/molecules27196608","volume":"27","author":"Mir","year":"2022","journal-title":"Molecules"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.addr.2019.01.002","volume":"143","author":"Zhao","year":"2019","journal-title":"Adv Drug Deliv Rev"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"552","DOI":"10.3390\/nano12030552","volume":"12","author":"Anastasiadis","year":"2022","journal-title":"Nanomaterials"},{"key":"ref62","first-page":"125","volume":"36","author":"Bhole","year":"2021","journal-title":"Turk Onkoloji Dergisi"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1158\/0008-5472.CAN-13-2387","volume":"74","author":"Zackrisson","year":"2014","journal-title":"Cancer Res"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"041006","DOI":"10.1117\/1.JBO.22.4.041006","volume":"22","author":"Upputuri","year":"2017","journal-title":"J Biomed Opt"},{"key":"ref65","volume-title":"Nanotechnology-Based Precision Tools for the Detection and Treatment of Cancer","year":"2015"},{"key":"ref66","doi-asserted-by":"publisher","first-page":"122570","DOI":"10.1016\/j.ijpharm.2022.122570","volume":"632","author":"Khizar","year":"2023","journal-title":"Int J Pharm"},{"key":"ref67","doi-asserted-by":"publisher","first-page":"5905","DOI":"10.3390\/molecules26195905","volume":"26","author":"Adepu","year":"2021","journal-title":"Molecules"},{"key":"ref68","doi-asserted-by":"publisher","first-page":"2999","DOI":"10.1515\/nanoph-2021-0254","volume":"10","author":"Bessiere","year":"2021","journal-title":"Nanophotonics"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"1296","DOI":"10.7150\/thno.41578","volume":"10","author":"Sun","year":"2020","journal-title":"Theranostics"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"3788","DOI":"10.1039\/D0QM00922A","volume":"5","author":"Escudero","year":"2021","journal-title":"Mater Chem Front"},{"key":"ref71","doi-asserted-by":"publisher","first-page":"82","DOI":"10.3390\/bioengineering9020082","volume":"9","author":"Plekhova","year":"2022","journal-title":"Bioengineering"},{"key":"ref72","doi-asserted-by":"publisher","first-page":"10897","DOI":"10.1039\/D0TB02085K","volume":"8","author":"Das","year":"2020","journal-title":"J Mater Chem B"},{"key":"ref73","doi-asserted-by":"publisher","first-page":"7909","DOI":"10.1039\/D1TB01310F","volume":"9","author":"Li","year":"2021","journal-title":"J Mater Chem B"},{"key":"ref74","doi-asserted-by":"publisher","first-page":"1706320","DOI":"10.1002\/adma.201706320","volume":"30","author":"Vankayala","year":"2018","journal-title":"Adv Mater"},{"key":"ref75","doi-asserted-by":"publisher","first-page":"83","DOI":"10.3390\/biom14010083","volume":"14","author":"Yang","year":"2024","journal-title":"Biomolecules"},{"key":"ref76","doi-asserted-by":"publisher","first-page":"100094","DOI":"10.1016\/j.onano.2022.100094","volume":"8","author":"Nahhas","year":"2022","journal-title":"OpenNano"},{"key":"ref77","doi-asserted-by":"publisher","first-page":"100035","DOI":"10.1016\/j.mtbio.2019.100035","volume":"5","author":"Gao","year":"2019","journal-title":"Mater Today Bio"},{"key":"ref78","doi-asserted-by":"publisher","first-page":"682","DOI":"10.3390\/pharmaceutics17060682","volume":"17","author":"Mousavi-Kiasary","year":"2025","journal-title":"Pharmaceutics"},{"key":"ref79","doi-asserted-by":"publisher","first-page":"2504672","DOI":"10.1002\/advs.202504672","volume":"12","author":"Zhou","year":"2025","journal-title":"Adv Sci"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/114111","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/114111","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T16:00:18Z","timestamp":1776268818000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/nanomedicine-integrated-phototherapy-for-cancer-theranostics-a-systema-peer-reviewed-fulltext-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":79,"URL":"https:\/\/doi.org\/10.2147\/ijn.s596646","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]}}}