{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T22:41:32Z","timestamp":1791326492553,"version":"4.3.1"},"reference-count":287,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJN"],"DOI":"10.2147\/ijn.s604563","type":"journal-article","created":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T04:15:26Z","timestamp":1778645726000},"page":"1-40","source":"Crossref","is-referenced-by-count":4,"title":["Key Tumor Responsive ZIF-8 Nanocarriers for Effective Anti-Cancer Therapeutics"],"prefix":"10.2147","volume":"Volume 21","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-6189-5979","authenticated-orcid":true,"given":"Wenjing","family":"He","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyu","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0650-9586","authenticated-orcid":true,"given":"Zhuochen","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debiao","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3322\/caac.21871","volume":"75","author":"Siegel","year":"2025","journal-title":"CA Cancer J Clin"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"229","DOI":"10.3322\/caac.21834","volume":"74","author":"Bray","year":"2024","journal-title":"CA Cancer J Clin"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1085\/jgp.8.6.519","volume":"8","author":"Warburg","year":"1927","journal-title":"J Gen Physiol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"e1005758","DOI":"10.1371\/journal.pcbi.1005758","volume":"13","author":"Damiani","year":"2017","journal-title":"PLoS Comput Biol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1002\/nbm.1644","volume":"24","author":"Hashim","year":"2011","journal-title":"NMR Biomed"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1158\/2326-6066.CIR-18-0481","volume":"7","author":"Harmon","year":"2019","journal-title":"Cancer Immunol Res"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1007\/s10555-019-09787-4","volume":"38","author":"Ibrahim-Hashim","year":"2019","journal-title":"Cancer Metastasis Rev"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"3244","DOI":"10.3390\/cancers12113244","volume":"12","author":"P\u00e9rez-Tom\u00e1s","year":"2020","journal-title":"Cancers"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1016\/j.ccell.2014.10.006","volume":"26","author":"Jain","year":"2014","journal-title":"Cancer Cell"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1186\/s12943-019-1089-9","volume":"18","author":"Jing","year":"2019","journal-title":"Mol Cancer"},{"key":"ref11","first-page":"307","volume":"62","author":"Kuppusamy","year":"2002","journal-title":"Cancer Res"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1002\/cbf.1149","volume":"22","author":"Balendiran","year":"2004","journal-title":"Cell Biochem Funct"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1038\/nrc1456","volume":"4","author":"Heldin","year":"2004","journal-title":"Nat Rev Cancer"},{"key":"ref14","first-page":"3039","volume":"47","author":"Jain","year":"1987","journal-title":"Cancer Res"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1186\/s12929-022-00866-3","volume":"29","author":"Tiwari","year":"2022","journal-title":"J Biomed Sci"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1016","DOI":"10.7150\/thno.51777","volume":"11","author":"Chen","year":"2021","journal-title":"Theranostics"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"5357","DOI":"10.1016\/j.cell.2021.09.006","volume":"184","author":"Wang","year":"2021","journal-title":"Cell"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"e10293","DOI":"10.1002\/adma.202510293","volume":"38","author":"Wu","year":"2026","journal-title":"Adv Mater"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1038\/s41392-023-01536-y","volume":"8","author":"Fan","year":"2023","journal-title":"Signal Transduct Target Ther"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"213925","DOI":"10.1016\/j.bioadv.2024.213925","volume":"162","author":"Resina","year":"2024","journal-title":"Biomater Adv"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"3173","DOI":"10.1021\/acs.molpharmaceut.3c01171","volume":"21","author":"Yamashita","year":"2024","journal-title":"Mol Pharm"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"7531","DOI":"10.1021\/ja413036q","volume":"136","author":"Harnoy","year":"2014","journal-title":"J Am Chem Soc"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"2594","DOI":"10.1021\/acs.biomac.7b00710","volume":"18","author":"Saxena","year":"2017","journal-title":"Biomacromolecules"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1186\/s11671-023-03939-w","volume":"18","author":"Foglietta","year":"2023","journal-title":"Discov Nano"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"4989","DOI":"10.2147\/IJN.S379200","volume":"17","author":"Adilakshmi","year":"2022","journal-title":"Int J Nanomedicine"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.jcis.2019.04.032","volume":"548","author":"Jia","year":"2019","journal-title":"J Colloid Interface Sci"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"4862","DOI":"10.1021\/acsami.1c19022","volume":"14","author":"Roy","year":"2022","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"111464","DOI":"10.1016\/j.colsurfb.2020.111464","volume":"198","author":"Yao","year":"2021","journal-title":"Colloids Surf B Biointerfaces"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1021\/acsomega.3c07226","volume":"9","author":"Koide","year":"2023","journal-title":"ACS Omega"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"10967","DOI":"10.1021\/acsami.8b21012","volume":"11","author":"Xue","year":"2019","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/j.jconrel.2021.06.003","volume":"335","author":"Li","year":"2021","journal-title":"J Control Release"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1080\/17435889.2025.2598331","volume":"21","author":"Tan","year":"2026","journal-title":"Nanomedicine"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"139221","DOI":"10.1016\/j.jhazmat.2025.139221","volume":"496","author":"Chen","year":"2025","journal-title":"J Hazard Mater"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"100801","DOI":"10.1016\/j.ceja.2025.100801","volume":"23","author":"Limtongnoi","year":"2025","journal-title":"Chemical Engineering Journal Advances"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"18793","DOI":"10.1038\/s41598-025-03542-2","volume":"15","author":"Mirzanejad","year":"2025","journal-title":"Sci Rep"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"1096","DOI":"10.1039\/d3tb02571c","volume":"12","author":"Iranpour","year":"2024","journal-title":"J Mater Chem B"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"6906","DOI":"10.1039\/c2dt30357d","volume":"41","author":"Sun","year":"2012","journal-title":"Dalton Trans"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"37600","DOI":"10.1039\/d0ra07950b","volume":"10","author":"Wang","year":"2020","journal-title":"RSC Adv"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"3158","DOI":"10.1021\/acs.molpharmaceut.5b00043","volume":"12","author":"Adhikari","year":"2015","journal-title":"Mol Pharm"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s12951-023-01771-z","volume":"21","author":"Shen","year":"2023","journal-title":"J Nanobiotechnology"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"1379365","DOI":"10.3389\/fimmu.2024.1379365","volume":"15","author":"Gao","year":"2024","journal-title":"Front Immunol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"4263","DOI":"10.1021\/acs.biomac.3c00557","volume":"24","author":"Lim","year":"2023","journal-title":"Biomacromolecules"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1016\/j.ijbiomac.2021.02.161","volume":"178","author":"Kulkarni","year":"2021","journal-title":"Int J Biol Macromol"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"10331","DOI":"10.1038\/s41598-022-14630-y","volume":"12","author":"Mittal","year":"2022","journal-title":"Sci Rep"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"37705","DOI":"10.1038\/srep37705","volume":"6","author":"Gao","year":"2016","journal-title":"Sci Rep"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"7936","DOI":"10.1039\/c8tb02308e","volume":"6","author":"Hu","year":"2018","journal-title":"J Mater Chem B"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"26612","DOI":"10.1021\/acsnano.5c05749","volume":"19","author":"Guo","year":"2025","journal-title":"ACS Nano"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"2486","DOI":"10.1039\/C8CE00333E","volume":"20","author":"Samal","year":"2018","journal-title":"CrystEngComm"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"2927","DOI":"10.1039\/C9TC06530J","volume":"8","author":"Ji","year":"2020","journal-title":"Journal of Materials Chemistry C"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"3489","DOI":"10.1021\/cg300552w","volume":"12","author":"Martinez Joaristi","year":"2012","journal-title":"Crystal Growth & Design"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"1058","DOI":"10.2174\/138161212799315777","volume":"18","author":"Muller","year":"2012","journal-title":"Curr Pharm Des"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"1786","DOI":"10.1007\/s13346-024-01714-7","volume":"15","author":"Adibifar","year":"2025","journal-title":"Drug Deliv Transl Res"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"31067","DOI":"10.1038\/s41598-024-82291-0","volume":"14","author":"Wang","year":"2024","journal-title":"Sci Rep"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"1477409","DOI":"10.3389\/fphar.2024.1477409","volume":"15","author":"Wang","year":"2024","journal-title":"Front Pharmacol"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"2375","DOI":"10.1039\/d1dt00116g","volume":"50","author":"Kamal","year":"2021","journal-title":"Dalton Trans"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"3328","DOI":"10.1021\/acs.molpharmaceut.0c00421","volume":"17","author":"Lin","year":"2020","journal-title":"Mol Pharm"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"1906","DOI":"10.3390\/polym12091906","volume":"12","author":"Kang","year":"2020","journal-title":"Polymers"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"e2302952","DOI":"10.1002\/smll.202302952","volume":"19","author":"Zhou","year":"2023","journal-title":"Small"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"125816","DOI":"10.1016\/j.ijpharm.2025.125816","volume":"681","author":"Tasleem","year":"2025","journal-title":"Int J Pharm"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"2242","DOI":"10.1016\/j.ymthe.2022.02.004","volume":"30","author":"Wan","year":"2022","journal-title":"Mol Ther"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"31998","DOI":"10.1021\/acsami.8b11972","volume":"10","author":"Dong","year":"2018","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"21587","DOI":"10.1021\/acsanm.3c03564","volume":"6","author":"Liu","year":"2023","journal-title":"ACS Applied Nano Materials"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.1007\/s00210-023-02707-y","volume":"397","author":"Oryani","year":"2024","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1089\/adt.2024.015","volume":"22","author":"Krishnan","year":"2024","journal-title":"Assay Drug Dev Technol"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"1625","DOI":"10.2147\/IJN.S241428","volume":"15","author":"Haggag","year":"2020","journal-title":"Int J Nanomedicine"},{"key":"ref66","doi-asserted-by":"publisher","first-page":"20304","DOI":"10.1021\/acsami.8b22693","volume":"11","author":"Ren","year":"2019","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref67","doi-asserted-by":"publisher","first-page":"7004","DOI":"10.1021\/acsami.1c01089","volume":"13","author":"Lawson","year":"2021","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref68","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.1080\/10717544.2022.2058649","volume":"29","author":"Peng","year":"2022","journal-title":"Drug Deliv"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"112544","DOI":"10.1016\/j.micromeso.2023.112544","volume":"354","author":"Zeyni","year":"2023","journal-title":"Microporous and Mesoporous Materials"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"134288","DOI":"10.1016\/j.colsurfa.2024.134288","volume":"696","author":"Nguyen","year":"2024","journal-title":"Colloids and Surfaces A"},{"key":"ref71","doi-asserted-by":"publisher","first-page":"111759","DOI":"10.1016\/j.colsurfb.2021.111759","volume":"203","author":"Yu","year":"2021","journal-title":"Colloids Surf B Biointerfaces"},{"key":"ref72","doi-asserted-by":"publisher","first-page":"125343","DOI":"10.1016\/j.ijpharm.2025.125343","volume":"672","author":"Zeng","year":"2025","journal-title":"Int J Pharm"},{"key":"ref73","doi-asserted-by":"publisher","first-page":"879988","DOI":"10.3389\/fbioe.2022.879988","volume":"10","author":"Kong","year":"2022","journal-title":"Front Bioeng Biotechnol"},{"key":"ref74","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1021\/acs.bioconjchem.3c00174","volume":"34","author":"Tenchov","year":"2023","journal-title":"Bioconjug Chem"},{"key":"ref75","doi-asserted-by":"publisher","first-page":"5523","DOI":"10.2147\/IJN.S462480","volume":"19","author":"Wang","year":"2024","journal-title":"Int J Nanomedicine"},{"key":"ref76","doi-asserted-by":"publisher","first-page":"13857","DOI":"10.2147\/IJN.S558675","volume":"20","author":"Jin","year":"2025","journal-title":"Int J Nanomedicine"},{"key":"ref77","doi-asserted-by":"publisher","first-page":"19648","DOI":"10.1021\/acsami.1c01943","volume":"13","author":"He","year":"2021","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref78","doi-asserted-by":"publisher","first-page":"1700270","DOI":"10.1002\/smtd.201700270","volume":"1","author":"Yan","year":"2017","journal-title":"Small Methods"},{"key":"ref79","doi-asserted-by":"publisher","first-page":"2051","DOI":"10.1126\/science.288.5473.2051","volume":"288","author":"Oldenborg","year":"2000","journal-title":"Science"},{"key":"ref80","doi-asserted-by":"publisher","first-page":"2107791","DOI":"10.1002\/adfm.202107791","volume":"32","author":"Qiao","year":"2021","journal-title":"Advanced Functional Materials"},{"key":"ref81","doi-asserted-by":"publisher","first-page":"7194","DOI":"10.1039\/c9ra09233a","volume":"10","author":"Xiao","year":"2020","journal-title":"RSC Adv"},{"key":"ref82","doi-asserted-by":"publisher","first-page":"971","DOI":"10.21037\/atm-22-3646","volume":"10","author":"Zhao","year":"2022","journal-title":"Ann Transl Med"},{"key":"ref83","doi-asserted-by":"publisher","first-page":"563555","DOI":"10.2147\/IJN.S563555","volume":"21","author":"Zhao","year":"2026","journal-title":"Int J Nanomedicine"},{"key":"ref84","doi-asserted-by":"publisher","first-page":"34268","DOI":"10.1021\/acsami.9b12641","volume":"11","author":"Qin","year":"2019","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref85","doi-asserted-by":"publisher","first-page":"2791","DOI":"10.7150\/thno.34740","volume":"9","author":"Liu","year":"2019","journal-title":"Theranostics"},{"key":"ref86","doi-asserted-by":"publisher","first-page":"31519","DOI":"10.1021\/acsami.7b09583","volume":"9","author":"Zhang","year":"2017","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref87","doi-asserted-by":"publisher","first-page":"1657","DOI":"10.3390\/ph18111657","volume":"18","author":"Yang","year":"2025","journal-title":"Pharmaceuticals"},{"key":"ref88","doi-asserted-by":"publisher","first-page":"42758","DOI":"10.1038\/s41598-025-27104-8","volume":"15","author":"Yang","year":"2025","journal-title":"Sci Rep"},{"key":"ref89","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1186\/s13046-022-02372-8","volume":"41","author":"Fan","year":"2022","journal-title":"J Exp Clin Cancer Res"},{"key":"ref90","doi-asserted-by":"publisher","first-page":"e2301328","DOI":"10.1002\/adhm.202301328","volume":"12","author":"Fang","year":"2023","journal-title":"Adv Healthc Mater"},{"key":"ref91","doi-asserted-by":"publisher","first-page":"129233","DOI":"10.1016\/j.ijbiomac.2024.129233","volume":"259","author":"Saeinasab","year":"2024","journal-title":"Int J Biol Macromol"},{"key":"ref92","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1186\/s12951-025-03521-9","volume":"23","author":"Gong","year":"2025","journal-title":"J Nanobiotechnology"},{"key":"ref93","doi-asserted-by":"publisher","first-page":"125692","DOI":"10.1016\/j.ijbiomac.2023.125692","volume":"247","author":"Cui","year":"2023","journal-title":"Int J Biol Macromol"},{"key":"ref94","doi-asserted-by":"publisher","first-page":"4647","DOI":"10.1038\/s41467-023-40345-3","volume":"14","author":"Huang","year":"2023","journal-title":"Nat Commun"},{"key":"ref95","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1016\/j.actbio.2024.02.030","volume":"178","author":"Yu","year":"2024","journal-title":"Acta Biomater"},{"key":"ref96","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1186\/s12951-025-03793-1","volume":"23","author":"Zhou","year":"2025","journal-title":"J Nanobiotechnology"},{"key":"ref97","doi-asserted-by":"publisher","first-page":"10395","DOI":"10.1038\/s41467-024-53906-x","volume":"15","author":"Song","year":"2024","journal-title":"Nat Commun"},{"key":"ref98","doi-asserted-by":"publisher","first-page":"47407","DOI":"10.1021\/acsami.1c16154","volume":"13","author":"Zhou","year":"2021","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref99","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/j.actbio.2024.09.015","volume":"188","author":"Yan","year":"2024","journal-title":"Acta Biomater"},{"key":"ref100","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1016\/j.bioactmat.2022.08.028","volume":"21","author":"Li","year":"2022","journal-title":"Bioact Mater"},{"key":"ref101","doi-asserted-by":"publisher","first-page":"e2501542","DOI":"10.1002\/advs.202501542","volume":"12","author":"Li","year":"2025","journal-title":"Adv Sci"},{"key":"ref102","doi-asserted-by":"publisher","first-page":"34588","DOI":"10.1021\/acsami.0c08315","volume":"12","author":"Wang","year":"2020","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref103","doi-asserted-by":"publisher","first-page":"e2302700","DOI":"10.1002\/advs.202302700","volume":"10","author":"Chen","year":"2023","journal-title":"Adv Sci"},{"key":"ref104","doi-asserted-by":"publisher","first-page":"171777","DOI":"10.1016\/j.cej.2025.171777","volume":"527","author":"Feng","year":"2026","journal-title":"Chemical Engineering Journal"},{"key":"ref105","doi-asserted-by":"publisher","first-page":"119983","DOI":"10.1016\/j.biomaterials.2020.119983","volume":"245","author":"Zhang","year":"2020","journal-title":"Biomaterials"},{"key":"ref106","doi-asserted-by":"publisher","first-page":"1656","DOI":"10.1080\/1061186X.2025.2519602","volume":"33","author":"Qi","year":"2025","journal-title":"J Drug Target"},{"key":"ref107","doi-asserted-by":"publisher","first-page":"2213364","DOI":"10.1002\/adfm.202213364","volume":"33","author":"Pan","year":"2023","journal-title":"Advanced Functional Materials"},{"key":"ref108","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1186\/s12951-025-03229-w","volume":"23","author":"Hu","year":"2025","journal-title":"J Nanobiotechnology"},{"key":"ref109","doi-asserted-by":"publisher","first-page":"4379","DOI":"10.1021\/acsanm.2c05472","volume":"6","author":"Jannatun","year":"2023","journal-title":"ACS Applied Nano Materials"},{"key":"ref110","doi-asserted-by":"publisher","first-page":"1147064","DOI":"10.3389\/fbioe.2023.1147064","volume":"11","author":"Du","year":"2023","journal-title":"Front Bioeng Biotechnol"},{"key":"ref111","doi-asserted-by":"publisher","first-page":"6377","DOI":"10.2147\/IJN.S387715","volume":"17","author":"Wu","year":"2022","journal-title":"Int J Nanomedicine"},{"key":"ref112","doi-asserted-by":"publisher","first-page":"44601","DOI":"10.1021\/acsomega.3c04973","volume":"8","author":"Gao","year":"2023","journal-title":"ACS Omega"},{"key":"ref113","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s43939-025-00229-3","volume":"5","author":"Subhadarshini","year":"2025","journal-title":"Discover Materials"},{"key":"ref114","doi-asserted-by":"publisher","first-page":"9222","DOI":"10.1039\/d0ra10423j","volume":"11","author":"Tran","year":"2021","journal-title":"RSC Adv"},{"key":"ref115","doi-asserted-by":"publisher","first-page":"4313","DOI":"10.3390\/molecules25184313","volume":"25","author":"AlNeyadi","year":"2020","journal-title":"Molecules"},{"key":"ref116","doi-asserted-by":"publisher","first-page":"5989","DOI":"10.1021\/acs.nanolett.4c04628","volume":"25","author":"Wan","year":"2025","journal-title":"Nano Lett"},{"key":"ref117","doi-asserted-by":"publisher","first-page":"159223","DOI":"10.1016\/j.cej.2025.159223","volume":"505","author":"Xia","year":"2025","journal-title":"Chemical Engineering Journal"},{"key":"ref118","doi-asserted-by":"publisher","first-page":"57343","DOI":"10.1021\/acsami.0c16689","volume":"12","author":"Huang","year":"2020","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref119","doi-asserted-by":"publisher","first-page":"9983","DOI":"10.1038\/s41598-024-57664-0","volume":"14","author":"Zhang","year":"2024","journal-title":"Sci Rep"},{"key":"ref120","doi-asserted-by":"publisher","first-page":"3068","DOI":"10.1200\/JCO.2000.18.17.3068","volume":"18","author":"von der Maase","year":"2000","journal-title":"J Clin Oncol"},{"key":"ref121","doi-asserted-by":"publisher","first-page":"1618","DOI":"10.1200\/JCO.22.00763","volume":"41","author":"Coleman","year":"2023","journal-title":"J Clin Oncol"},{"key":"ref122","doi-asserted-by":"publisher","first-page":"117696","DOI":"10.1016\/j.carbpol.2021.117696","volume":"259","author":"Lakkakula","year":"2021","journal-title":"Carbohydr Polym"},{"key":"ref123","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.jconrel.2021.12.030","volume":"342","author":"Park","year":"2022","journal-title":"J Control Release"},{"key":"ref124","doi-asserted-by":"publisher","first-page":"589815","DOI":"10.2147\/IJN.S589815","volume":"21","author":"Li","year":"2026","journal-title":"Int J Nanomedicine"},{"key":"ref125","doi-asserted-by":"publisher","first-page":"7985","DOI":"10.2147\/IJN.S438771","volume":"18","author":"Wu","year":"2023","journal-title":"Int J Nanomedicine"},{"key":"ref126","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1007\/s10570-021-04267-x","volume":"29","author":"Liu","year":"2022","journal-title":"Cellulose"},{"key":"ref127","doi-asserted-by":"publisher","first-page":"126152","DOI":"10.1016\/j.ijpharm.2025.126152","volume":"684","author":"Thrivikraman","year":"2025","journal-title":"Int J Pharm"},{"key":"ref128","doi-asserted-by":"publisher","first-page":"105467","DOI":"10.1016\/j.bioorg.2021.105467","volume":"118","author":"Abd Al-Jabbar","year":"2022","journal-title":"Bioorg Chem"},{"key":"ref129","doi-asserted-by":"publisher","first-page":"eadv6990","DOI":"10.1126\/sciadv.adv6990","volume":"11","author":"Gu","year":"2025","journal-title":"Sci Adv"},{"key":"ref130","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1021\/mp700113r","volume":"4","author":"Anand","year":"2007","journal-title":"Mol Pharm"},{"key":"ref131","doi-asserted-by":"publisher","first-page":"3886","DOI":"10.3390\/molecules29163886","volume":"29","author":"Wen","year":"2024","journal-title":"Molecules"},{"key":"ref132","doi-asserted-by":"publisher","first-page":"1941","DOI":"10.3390\/polym17141941","volume":"17","author":"Dur\u00e1n-Egido","year":"2025","journal-title":"Polymers"},{"key":"ref133","doi-asserted-by":"publisher","first-page":"e70227","DOI":"10.1002\/aoc.70227","volume":"39","author":"Amur","year":"2025","journal-title":"Applied Organometallic Chemistry"},{"key":"ref134","doi-asserted-by":"publisher","first-page":"12598","DOI":"10.1038\/s41598-017-12786-6","volume":"7","author":"Tiwari","year":"2017","journal-title":"Sci Rep"},{"key":"ref135","doi-asserted-by":"publisher","first-page":"3847","DOI":"10.2147\/IJN.S451042","volume":"19","author":"Yan","year":"2024","journal-title":"Int J Nanomedicine"},{"key":"ref136","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.tips.2019.03.002","volume":"40","author":"Noel","year":"2019","journal-title":"Trends Pharmacol Sci"},{"key":"ref137","doi-asserted-by":"publisher","first-page":"104098","DOI":"10.1016\/j.jddst.2022.104098","volume":"79","author":"Reshmi","year":"2023","journal-title":"Journal of Drug Delivery Science and Technology"},{"key":"ref138","doi-asserted-by":"publisher","first-page":"e202500732","DOI":"10.1002\/cmdc.202500732","volume":"21","author":"Han","year":"2026","journal-title":"ChemMedChem"},{"key":"ref139","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/s12575-024-00229-2","volume":"26","author":"Sameni","year":"2024","journal-title":"Biol Proced Online"},{"key":"ref140","doi-asserted-by":"publisher","first-page":"12939","DOI":"10.2147\/IJN.S553945","volume":"20","author":"Guo","year":"2025","journal-title":"Int J Nanomedicine"},{"key":"ref141","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.jconrel.2023.07.054","volume":"361","author":"El Moukhtari","year":"2023","journal-title":"J Control Release"},{"key":"ref142","doi-asserted-by":"publisher","first-page":"113567","DOI":"10.1016\/j.colsurfb.2023.113567","volume":"231","author":"Wang","year":"2023","journal-title":"Colloids Surf B Biointerfaces"},{"key":"ref143","doi-asserted-by":"publisher","first-page":"dmm047662","DOI":"10.1242\/dmm.047662","volume":"14","author":"Hill","year":"2021","journal-title":"Dis Model Mech"},{"key":"ref144","doi-asserted-by":"publisher","first-page":"e252","DOI":"10.1038\/mtna.2015.23","volume":"4","author":"Lam","year":"2015","journal-title":"Mol Ther Nucleic Acids"},{"key":"ref145","doi-asserted-by":"publisher","first-page":"2932","DOI":"10.3390\/ijms25052932","volume":"25","author":"Li","year":"2024","journal-title":"Int J Mol Sci"},{"key":"ref146","doi-asserted-by":"publisher","first-page":"124820","DOI":"10.1016\/j.talanta.2023.124820","volume":"265","author":"Zhang","year":"2023","journal-title":"Talanta"},{"key":"ref147","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1038\/s41392-023-01309-7","volume":"8","author":"Li","year":"2023","journal-title":"Signal Transduct Target Ther"},{"key":"ref148","doi-asserted-by":"publisher","first-page":"1727","DOI":"10.1038\/s41467-024-45998-2","volume":"15","author":"Chen","year":"2024","journal-title":"Nat Commun"},{"key":"ref149","doi-asserted-by":"publisher","first-page":"614","DOI":"10.7150\/thno.47007","volume":"11","author":"Zhang","year":"2021","journal-title":"Theranostics"},{"key":"ref150","doi-asserted-by":"publisher","first-page":"15406","DOI":"10.1039\/d0cc06241c","volume":"56","author":"Poddar","year":"2020","journal-title":"Chem Commun"},{"key":"ref151","doi-asserted-by":"publisher","first-page":"5258","DOI":"10.3390\/ijms20215258","volume":"20","author":"Mammadova-Bach","year":"2019","journal-title":"Int J Mol Sci"},{"key":"ref152","doi-asserted-by":"publisher","first-page":"215535","DOI":"10.1016\/j.ccr.2023.215535","volume":"500","author":"Wang","year":"2024","journal-title":"Coordination Chemistry Reviews"},{"key":"ref153","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/s0006-2952(01)00624-4","volume":"62","author":"Chimienti","year":"2001","journal-title":"Biochem Pharmacol"},{"key":"ref154","doi-asserted-by":"publisher","first-page":"e2015786118","DOI":"10.1073\/pnas.2015786118","volume":"118","author":"Anson","year":"2021","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref155","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1042\/bj3460241","volume":"346","author":"Huang","year":"2000","journal-title":"Biochem J"},{"key":"ref156","doi-asserted-by":"publisher","first-page":"e2321216121","DOI":"10.1073\/pnas.2321216121","volume":"121","author":"Holtzen","year":"2024","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref157","doi-asserted-by":"publisher","first-page":"47524","DOI":"10.1074\/jbc.M108834200","volume":"276","author":"Jiang","year":"2001","journal-title":"J Biol Chem"},{"key":"ref158","doi-asserted-by":"publisher","first-page":"45032","DOI":"10.1038\/srep45032","volume":"7","author":"Mortadza","year":"2017","journal-title":"Sci Rep"},{"key":"ref159","doi-asserted-by":"publisher","first-page":"e2103534","DOI":"10.1002\/advs.202103534","volume":"9","author":"Wu","year":"2022","journal-title":"Adv Sci"},{"key":"ref160","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1007\/s40820-023-01193-4","volume":"15","author":"Zhao","year":"2023","journal-title":"Nanomicro Lett"},{"key":"ref161","doi-asserted-by":"publisher","first-page":"3028","DOI":"10.7150\/ijbs.95929","volume":"20","author":"Li","year":"2024","journal-title":"Int J Biol Sci"},{"key":"ref162","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1007\/s13238-021-00881-4","volume":"13","author":"Ma","year":"2022","journal-title":"Protein Cell"},{"key":"ref163","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1046\/j.1471-4159.2003.01678.x","volume":"85","author":"Dineley","year":"2003","journal-title":"J Neurochem"},{"key":"ref164","doi-asserted-by":"publisher","first-page":"114601","DOI":"10.1016\/j.taap.2019.114601","volume":"377","author":"Qi","year":"2019","journal-title":"Toxicol Appl Pharmacol"},{"key":"ref165","doi-asserted-by":"publisher","first-page":"2210","DOI":"10.31635\/ccschem.023.202303514","volume":"6","author":"Yang","year":"2024","journal-title":"CCS Chemistry"},{"key":"ref166","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.freeradbiomed.2017.03.032","volume":"108","author":"Salazar","year":"2017","journal-title":"Free Radic Biol Med"},{"key":"ref167","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1038\/s41419-020-2384-5","volume":"11","author":"Zhang","year":"2020","journal-title":"Cell Death Dis"},{"key":"ref168","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1007\/BF02112356","volume":"15","author":"Verbost","year":"1996","journal-title":"Fish Physiol Biochem"},{"key":"ref169","doi-asserted-by":"publisher","first-page":"RP88082","DOI":"10.7554\/eLife.88082","volume":"12","author":"Akizawa","year":"2023","journal-title":"eLife"},{"key":"ref170","doi-asserted-by":"publisher","first-page":"e62601","DOI":"10.7554\/eLife.62601","volume":"9","author":"Preissler","year":"2020","journal-title":"eLife"},{"key":"ref171","doi-asserted-by":"publisher","first-page":"1422","DOI":"10.1038\/s41556-025-01730-w","volume":"27","author":"Leder","year":"2025","journal-title":"Nat Cell Biol"},{"key":"ref172","doi-asserted-by":"publisher","first-page":"2630","DOI":"10.1021\/bi062106y","volume":"46","author":"Butler","year":"2007","journal-title":"Biochemistry"},{"key":"ref173","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.freeradbiomed.2019.12.017","volume":"147","author":"Anzai","year":"2020","journal-title":"Free Radic Biol Med"},{"key":"ref174","doi-asserted-by":"publisher","first-page":"11161","DOI":"10.1038\/s41598-017-10574-w","volume":"7","author":"Rabdano","year":"2017","journal-title":"Sci Rep"},{"key":"ref175","doi-asserted-by":"publisher","first-page":"6787","DOI":"10.7150\/jca.62352","volume":"12","author":"Zhang","year":"2021","journal-title":"J Cancer"},{"key":"ref176","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1038\/nature17041","volume":"529","author":"Wang","year":"2016","journal-title":"Nature"},{"key":"ref177","doi-asserted-by":"publisher","first-page":"132","DOI":"10.3390\/biology11010132","volume":"11","author":"Gonnella","year":"2022","journal-title":"Biology"},{"key":"ref178","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1038\/sj.cdd.4401378","volume":"11","author":"Rao","year":"2004","journal-title":"Cell Death Differ"},{"key":"ref179","doi-asserted-by":"publisher","first-page":"2787","DOI":"10.2147\/DDDT.S209947","volume":"13","author":"Wu","year":"2019","journal-title":"Drug Des Devel Ther"},{"key":"ref180","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1186\/s12951-025-04003-8","volume":"24","author":"Xiu","year":"2026","journal-title":"J Nanobiotechnology"},{"key":"ref181","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1126\/science.aat1022","volume":"361","author":"Du","year":"2018","journal-title":"Science"},{"key":"ref182","doi-asserted-by":"publisher","first-page":"e2307278","DOI":"10.1002\/advs.202307278","volume":"11","author":"Sun","year":"2024","journal-title":"Adv Sci"},{"key":"ref183","doi-asserted-by":"publisher","first-page":"1148","DOI":"10.1038\/s41590-022-01267-2","volume":"23","author":"Christofides","year":"2022","journal-title":"Nat Immunol"},{"key":"ref184","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1186\/s12943-022-01645-2","volume":"21","author":"Bai","year":"2022","journal-title":"Mol Cancer"},{"key":"ref185","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1186\/s13045-020-00887-1","volume":"13","author":"Lu","year":"2020","journal-title":"J Hematol Oncol"},{"key":"ref186","doi-asserted-by":"publisher","first-page":"4191","DOI":"10.1002\/smll.201403838","volume":"11","author":"Su","year":"2015","journal-title":"Small"},{"key":"ref187","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1038\/s41577-019-0127-6","volume":"19","author":"DeNardo","year":"2019","journal-title":"Nat Rev Immunol"},{"key":"ref188","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1016\/s1471-4906(02)02302-5","volume":"23","author":"Mantovani","year":"2002","journal-title":"Trends Immunol"},{"key":"ref189","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1038\/s41551-018-0236-8","volume":"2","author":"Rodell","year":"2018","journal-title":"Nat Biomed Eng"},{"key":"ref190","doi-asserted-by":"publisher","first-page":"12579","DOI":"10.1021\/jacs.0c05039","volume":"142","author":"Ni","year":"2020","journal-title":"J Am Chem Soc"},{"key":"ref191","doi-asserted-by":"publisher","first-page":"11723","DOI":"10.1021\/acsomega.4c10865","volume":"10","author":"Li","year":"2025","journal-title":"ACS Omega"},{"key":"ref192","doi-asserted-by":"publisher","first-page":"eadu1647","DOI":"10.1126\/sciadv.adu1647","volume":"11","author":"Ding","year":"2025","journal-title":"Sci Adv"},{"key":"ref193","doi-asserted-by":"publisher","first-page":"9104","DOI":"10.1021\/acs.nanolett.4c02657","volume":"24","author":"Zhang","year":"2024","journal-title":"Nano Lett"},{"key":"ref194","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1186\/s12951-025-03870-5","volume":"23","author":"Peng","year":"2025","journal-title":"J Nanobiotechnology"},{"key":"ref195","doi-asserted-by":"publisher","first-page":"114707","DOI":"10.1016\/j.jconrel.2026.114707","volume":"392","author":"Zuo","year":"2026","journal-title":"J Control Release"},{"key":"ref196","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1038\/cr.2013.88","volume":"23","author":"Covarrubias","year":"2013","journal-title":"Cell Res"},{"key":"ref197","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1186\/s12943-022-01657-y","volume":"21","author":"Wu","year":"2022","journal-title":"Mol Cancer"},{"key":"ref198","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s12943-024-02208-3","volume":"24","author":"He","year":"2025","journal-title":"Mol Cancer"},{"key":"ref199","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1111\/j.1349-7006.2008.00854.x","volume":"99","author":"Murakami","year":"2008","journal-title":"Cancer Sci"},{"key":"ref200","doi-asserted-by":"publisher","first-page":"101541","DOI":"10.1016\/j.arr.2021.101541","volume":"74","author":"Baarz","year":"2022","journal-title":"Ageing Res Rev"},{"key":"ref201","doi-asserted-by":"publisher","first-page":"1350","DOI":"10.7150\/thno.121988","volume":"16","author":"Chen","year":"2026","journal-title":"Theranostics"},{"key":"ref202","doi-asserted-by":"publisher","first-page":"1903","DOI":"10.1038\/s41565-024-01758-3","volume":"19","author":"Tan","year":"2024","journal-title":"Nat Nanotechnol"},{"key":"ref203","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1038\/s41420-024-02104-1","volume":"10","author":"Jakobs","year":"2024","journal-title":"Cell Death Discov"},{"key":"ref204","doi-asserted-by":"publisher","first-page":"13668","DOI":"10.3390\/ijms222413668","volume":"22","author":"Ginefra","year":"2021","journal-title":"Int J Mol Sci"},{"key":"ref205","doi-asserted-by":"publisher","first-page":"mfaf018","DOI":"10.1093\/mtomcs\/mfaf018","volume":"17","author":"Kocy\u0142a","year":"2025","journal-title":"Metallomics"},{"key":"ref206","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.ccr.2016.07.002","volume":"327\u2013328","author":"Bellomo","year":"2016","journal-title":"Coord Chem Rev"},{"key":"ref207","doi-asserted-by":"publisher","first-page":"7841","DOI":"10.7150\/thno.117773","volume":"15","author":"Mu","year":"2025","journal-title":"Theranostics"},{"key":"ref208","doi-asserted-by":"publisher","first-page":"132","DOI":"10.2174\/187153009788452390","volume":"9","author":"H\u00f6nscheid","year":"2009","journal-title":"Endocr Metab Immune Disord Drug Targets"},{"key":"ref209","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1097\/HEP.0000000000000629","volume":"80","author":"Yang","year":"2024","journal-title":"Hepatology"},{"key":"ref210","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1038\/cdd.2014.137","volume":"22","author":"Galluzzi","year":"2015","journal-title":"Cell Death Differ"},{"key":"ref211","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1038\/s41418-017-0012-4","volume":"25","author":"Galluzzi","year":"2018","journal-title":"Cell Death Differ"},{"key":"ref212","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1038\/s41392-020-00449-4","volume":"6","author":"Tang","year":"2021","journal-title":"Signal Transduct Target Ther"},{"key":"ref213","doi-asserted-by":"publisher","first-page":"58754","DOI":"10.18632\/oncotarget.17678","volume":"8","author":"Xu","year":"2017","journal-title":"Oncotarget"},{"key":"ref214","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1038\/s41568-019-0183-z","volume":"19","author":"Feng","year":"2019","journal-title":"Nat Rev Cancer"},{"key":"ref215","doi-asserted-by":"publisher","first-page":"1573","DOI":"10.1126\/science.1208347","volume":"334","author":"Michaud","year":"2011","journal-title":"Science"},{"key":"ref216","doi-asserted-by":"publisher","first-page":"C1318","DOI":"10.1152\/ajpcell.00616.2005","volume":"291","author":"Bell","year":"2006","journal-title":"American Journal of Physiology-Cell Physiology"},{"key":"ref217","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.1038\/nm1622","volume":"13","author":"Apetoh","year":"2007","journal-title":"Nat Med"},{"key":"ref218","doi-asserted-by":"publisher","first-page":"9407","DOI":"10.1021\/acsnano.5c21475","volume":"20","author":"Li","year":"2026","journal-title":"ACS Nano"},{"key":"ref219","doi-asserted-by":"publisher","first-page":"394","DOI":"10.3390\/pharmaceutics18030394","volume":"18","author":"Hao","year":"2026","journal-title":"Pharmaceutics"},{"key":"ref220","doi-asserted-by":"publisher","first-page":"2474","DOI":"10.3390\/cells12202474","volume":"12","author":"Nazari","year":"2023","journal-title":"Cells"},{"key":"ref221","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1038\/s41580-018-0080-4","volume":"20","author":"Dongre","year":"2019","journal-title":"Nat Rev Mol Cell Biol"},{"key":"ref222","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1038\/nrm3758","volume":"15","author":"Lamouille","year":"2014","journal-title":"Nat Rev Mol Cell Biol"},{"key":"ref223","doi-asserted-by":"publisher","first-page":"1784","DOI":"10.1097\/JTO.0b013e31822adfb0","volume":"6","author":"Reka","year":"2011","journal-title":"J Thorac Oncol"},{"key":"ref224","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1007\/s10549-020-05627-0","volume":"181","author":"J\u00f8rgensen","year":"2020","journal-title":"Breast Cancer Res Treat"},{"key":"ref225","doi-asserted-by":"publisher","first-page":"143","DOI":"10.3390\/cells8020143","volume":"8","author":"Fontana","year":"2019","journal-title":"Cells"},{"key":"ref226","doi-asserted-by":"publisher","first-page":"917","DOI":"10.17179\/excli2020-1946","volume":"19","author":"Niknami","year":"2020","journal-title":"EXCLI J"},{"key":"ref227","doi-asserted-by":"publisher","first-page":"4845","DOI":"10.62347\/HFLG3477","volume":"15","author":"Chen","year":"2025","journal-title":"Am J Cancer Res"},{"key":"ref228","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1186\/s12885-018-4071-9","volume":"18","author":"Kim","year":"2018","journal-title":"BMC Cancer"},{"key":"ref229","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/s12951-021-01161-3","volume":"20","author":"Chen","year":"2022","journal-title":"J Nanobiotechnology"},{"key":"ref230","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.cell.2010.03.015","volume":"141","author":"Kessenbrock","year":"2010","journal-title":"Cell"},{"key":"ref231","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1161\/01.RES.0000070112.80711.3D","volume":"92","author":"Visse","year":"2003","journal-title":"Circ Res"},{"key":"ref232","doi-asserted-by":"publisher","first-page":"146","DOI":"10.3390\/ijms23010146","volume":"23","author":"Niland","year":"2021","journal-title":"Int J Mol Sci"},{"key":"ref233","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3390\/cells15010017","volume":"15","author":"Liu","year":"2025","journal-title":"Cells"},{"key":"ref234","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1186\/s12935-020-01719-5","volume":"21","author":"Emami Nejad","year":"2021","journal-title":"Cancer Cell Int"},{"key":"ref235","doi-asserted-by":"publisher","first-page":"1582305","DOI":"10.3389\/fimmu.2025.1582305","volume":"16","author":"Pan","year":"2025","journal-title":"Front Immunol"},{"key":"ref236","doi-asserted-by":"publisher","first-page":"139298","DOI":"10.1016\/j.jcis.2025.139298","volume":"704","author":"Yu","year":"2026","journal-title":"J Colloid Interface Sci"},{"key":"ref237","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1038\/s43246-024-00518-z","volume":"5","author":"Wang","year":"2024","journal-title":"Communications Materials"},{"key":"ref238","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1021\/acs.chemrev.8b00363","volume":"119","author":"Wahsner","year":"2019","journal-title":"Chem Rev"},{"key":"ref239","doi-asserted-by":"publisher","first-page":"110840","DOI":"10.1016\/j.ejrad.2023.110840","volume":"164","author":"Winder","year":"2023","journal-title":"Eur J Radiol"},{"key":"ref240","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1039\/c8cc08943d","volume":"55","author":"Lin","year":"2019","journal-title":"Chem Commun"},{"key":"ref241","doi-asserted-by":"publisher","first-page":"7386","DOI":"10.1007\/s10853-020-05647-7","volume":"56","author":"Zhou","year":"2021","journal-title":"Journal of Materials Science"},{"key":"ref242","doi-asserted-by":"publisher","first-page":"7683","DOI":"10.1039\/c9tb01651a","volume":"7","author":"Pan","year":"2019","journal-title":"J Mater Chem B"},{"key":"ref243","doi-asserted-by":"publisher","first-page":"13086","DOI":"10.1021\/acs.chemrev.1c00506","volume":"121","author":"Jiang","year":"2021","journal-title":"Chem Rev"},{"key":"ref244","doi-asserted-by":"publisher","first-page":"113917","DOI":"10.1016\/j.addr.2021.113917","volume":"179","author":"Yuan","year":"2021","journal-title":"Adv Drug Deliv Rev"},{"key":"ref245","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1016\/j.actbio.2021.10.006","volume":"137","author":"Guo","year":"2022","journal-title":"Acta Biomater"},{"key":"ref246","doi-asserted-by":"publisher","first-page":"3483","DOI":"10.3390\/jcm9113483","volume":"9","author":"Lang","year":"2020","journal-title":"J Clin Med"},{"key":"ref247","doi-asserted-by":"publisher","first-page":"177","DOI":"10.2174\/1874471013666191220105449","volume":"13","author":"Evangelista","year":"2020","journal-title":"Curr Radiopharm"},{"key":"ref248","doi-asserted-by":"publisher","first-page":"26881","DOI":"10.1038\/s41598-025-12725-w","volume":"15","author":"Damodaran","year":"2025","journal-title":"Sci Rep"},{"key":"ref249","doi-asserted-by":"publisher","first-page":"15209","DOI":"10.1007\/s00210-025-03963-w","volume":"398","author":"Shaik","year":"2025","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"ref250","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1038\/s41577-023-00973-8","volume":"24","author":"Butterfield","year":"2024","journal-title":"Nat Rev Immunol"},{"key":"ref251","doi-asserted-by":"publisher","first-page":"1579","DOI":"10.1186\/s12885-025-15039-2","volume":"25","author":"Li","year":"2025","journal-title":"BMC Cancer"},{"key":"ref252","doi-asserted-by":"publisher","first-page":"13063","DOI":"10.1038\/s41598-025-98018-8","volume":"15","author":"Zhou","year":"2025","journal-title":"Sci Rep"},{"key":"ref253","doi-asserted-by":"publisher","first-page":"1228","DOI":"10.3390\/pharmaceutics14061228","volume":"14","author":"Huang","year":"2022","journal-title":"Pharmaceutics"},{"key":"ref254","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1586\/14760584.2014.863715","volume":"13","author":"Shirota","year":"2014","journal-title":"Expert Rev Vaccines"},{"key":"ref255","doi-asserted-by":"publisher","first-page":"6377","DOI":"10.1016\/j.vaccine.2014.06.065","volume":"32","author":"Scheiermann","year":"2014","journal-title":"Vaccine"},{"key":"ref256","doi-asserted-by":"publisher","first-page":"eadj6380","DOI":"10.1126\/sciadv.adj6380","volume":"10","author":"Alsaiari","year":"2024","journal-title":"Sci Adv"},{"key":"ref257","doi-asserted-by":"publisher","first-page":"8845","DOI":"10.1038\/s41467-024-53015-9","volume":"15","author":"Bergeron","year":"2024","journal-title":"Nat Commun"},{"key":"ref258","doi-asserted-by":"publisher","first-page":"2916","DOI":"10.3390\/cancers12102916","volume":"12","author":"Krisnawan","year":"2020","journal-title":"Cancers"},{"key":"ref259","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1038\/s41577-019-0218-4","volume":"20","author":"Kalbasi","year":"2020","journal-title":"Nat Rev Immunol"},{"key":"ref260","doi-asserted-by":"publisher","first-page":"295","DOI":"10.7150\/thno.80687","volume":"13","author":"Yang","year":"2023","journal-title":"Theranostics"},{"key":"ref261","doi-asserted-by":"publisher","first-page":"100995","DOI":"10.1016\/j.apmt.2021.100995","volume":"23","author":"Wei","year":"2021","journal-title":"Applied Materials Today"},{"key":"ref262","doi-asserted-by":"publisher","first-page":"6919","DOI":"10.7150\/thno.110841","volume":"15","author":"Hu","year":"2025","journal-title":"Theranostics"},{"key":"ref263","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/s12935-021-02407-8","volume":"22","author":"Vafaei","year":"2022","journal-title":"Cancer Cell Int"},{"key":"ref264","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1007\/s10147-016-0959-z","volume":"21","author":"Hamanishi","year":"2016","journal-title":"Int J Clin Oncol"},{"key":"ref265","doi-asserted-by":"publisher","first-page":"817548","DOI":"10.3389\/fonc.2022.817548","volume":"12","author":"Frisone","year":"2022","journal-title":"Front Oncol"},{"key":"ref266","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1038\/s41392-025-02280-1","volume":"10","author":"Tufail","year":"2025","journal-title":"Signal Transduct Target Ther"},{"key":"ref267","doi-asserted-by":"publisher","first-page":"e17792","DOI":"10.1002\/advs.202517792","volume":"13","author":"Fang","year":"2026","journal-title":"Adv Sci"},{"key":"ref268","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1007\/s10238-024-01302-6","volume":"24","author":"Stiles","year":"2024","journal-title":"Clin Exp Med"},{"key":"ref269","doi-asserted-by":"publisher","first-page":"131364","DOI":"10.1016\/j.jhazmat.2023.131364","volume":"453","author":"Li","year":"2023","journal-title":"J Hazard Mater"},{"key":"ref270","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1080\/15376516.2018.1553221","volume":"29","author":"Singh","year":"2019","journal-title":"Toxicol Mech Methods"},{"key":"ref271","doi-asserted-by":"publisher","first-page":"e0164434","DOI":"10.1371\/journal.pone.0164434","volume":"11","author":"Wang","year":"2016","journal-title":"PLoS One"},{"key":"ref272","doi-asserted-by":"publisher","first-page":"22067","DOI":"10.3390\/ijms141122067","volume":"14","author":"Mizuno","year":"2013","journal-title":"Int J Mol Sci"},{"key":"ref273","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1016\/0306-4522(94)90282-8","volume":"60","author":"Koh","year":"1994","journal-title":"Neuroscience"},{"key":"ref274","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/s0006-8993(00)02944-9","volume":"886","author":"Kim","year":"2000","journal-title":"Brain Res"},{"key":"ref275","doi-asserted-by":"publisher","first-page":"3899","DOI":"10.2147\/DDDT.S87662","volume":"9","author":"Kocdor","year":"2015","journal-title":"Drug Des Devel Ther"},{"key":"ref276","doi-asserted-by":"publisher","first-page":"7619","DOI":"10.1039\/c9tb02131k","volume":"7","author":"Li","year":"2019","journal-title":"J Mater Chem B"},{"key":"ref277","doi-asserted-by":"publisher","first-page":"133498","DOI":"10.1016\/j.cej.2021.133498","volume":"433","author":"Zhang","year":"2022","journal-title":"Chemical Engineering Journal"},{"key":"ref278","doi-asserted-by":"publisher","first-page":"120395","DOI":"10.1016\/j.ijpharm.2021.120395","volume":"598","author":"Kunde","year":"2021","journal-title":"Int J Pharm"},{"key":"ref279","doi-asserted-by":"publisher","first-page":"12096","DOI":"10.1021\/acsnano.8b05292","volume":"12","author":"Deng","year":"2018","journal-title":"ACS Nano"},{"key":"ref280","doi-asserted-by":"publisher","first-page":"e2104594","DOI":"10.1002\/adma.202104594","volume":"33","author":"Duan","year":"2021","journal-title":"Adv Mater"},{"key":"ref281","doi-asserted-by":"publisher","first-page":"5035","DOI":"10.1021\/acs.iecr.2c04570","volume":"62","author":"Quan","year":"2023","journal-title":"Industrial & Engineering Chemistry Research"},{"key":"ref282","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1038\/s42004-021-00613-z","volume":"5","author":"Deacon","year":"2022","journal-title":"Commun Chem"},{"key":"ref283","doi-asserted-by":"publisher","first-page":"1645","DOI":"10.1039\/c4sc03217a","volume":"6","author":"Crawford","year":"2015","journal-title":"Chem Sci"},{"key":"ref284","doi-asserted-by":"publisher","first-page":"40","DOI":"10.3390\/separations12020040","volume":"12","author":"Su","year":"2025","journal-title":"Separations"},{"key":"ref285","doi-asserted-by":"publisher","first-page":"116586","DOI":"10.1016\/j.jece.2025.116586","volume":"13","author":"Tian","year":"2025","journal-title":"Journal of Environmental Chemical Engineering"},{"key":"ref286","doi-asserted-by":"publisher","first-page":"13039","DOI":"10.2147\/IJN.S554821","volume":"20","author":"Herdiana","year":"2025","journal-title":"Int J Nanomedicine"},{"key":"ref287","doi-asserted-by":"publisher","first-page":"13983","DOI":"10.1021\/acsnano.4c00182","volume":"18","author":"Anchordoquy","year":"2024","journal-title":"ACS Nano"}],"container-title":["International Journal of Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/115118","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/115118","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T04:15:30Z","timestamp":1778645730000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/key-tumor-responsive-zif-8-nanocarriers-for-effective-anti-cancer-ther-peer-reviewed-fulltext-article-IJN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":287,"URL":"https:\/\/doi.org\/10.2147\/ijn.s604563","relation":{},"ISSN":["1178-2013"],"issn-type":[{"value":"1178-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]}}}