{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T09:34:53Z","timestamp":1758274493842,"version":"3.40.5"},"reference-count":52,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJWH"],"DOI":"10.2147\/ijwh.s483139","type":"journal-article","created":{"date-parts":[[2024,11,9]],"date-time":"2024-11-09T06:05:12Z","timestamp":1731132312000},"page":"1889-1902","source":"Crossref","is-referenced-by-count":1,"title":["Causal Pathways Between Breast Cancer and Cardiovascular Disease Through Mediator Factors: A Two-Step Mendelian Randomization Analysis"],"prefix":"10.2147","volume":"Volume 16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5616-621X","authenticated-orcid":true,"given":"Weilin","family":"Lu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaiming","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haisi","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinyu","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7510-9735","authenticated-orcid":true,"given":"Xiaolin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5967-6721","authenticated-orcid":true,"given":"Zhipeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9124-303X","authenticated-orcid":true,"given":"Huae","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinxing","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2024,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"524","DOI":"10.3322\/caac.21754","volume":"72","author":"Giaquinto","year":"2022","journal-title":"CA Cancer J Clin"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"12","DOI":"10.3322\/caac.21820","volume":"74","author":"Siegel","year":"2024","journal-title":"CA Cancer J Clin"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1708","DOI":"10.1016\/j.cell.2023.01.040","volume":"186","author":"Nolan","year":"2023","journal-title":"Cell"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1559","DOI":"10.1002\/cncr.32648","volume":"126","author":"Afifi","year":"2020","journal-title":"Cancer"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1093\/jnci\/djaa097","volume":"113","author":"Blaes","year":"2021","journal-title":"J Natl Cancer Inst"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"3889","DOI":"10.1093\/eurheartj\/ehz766","volume":"40","author":"Sturgeon","year":"2019","journal-title":"Eur Heart J"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"2826","DOI":"10.1002\/cncr.34224","volume":"128","author":"Koric","year":"2022","journal-title":"Cancer"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1186\/s13058-023-01680-x","volume":"25","author":"M\u00f6hl","year":"2023","journal-title":"Breast Cancer Res"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"e30","DOI":"10.1161\/cir.0000000000000556","volume":"137","author":"Mehta","year":"2018","journal-title":"Circulation"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1001\/jamacardio.2016.3841","volume":"2","author":"Abdel-Qadir","year":"2017","journal-title":"JAMA Cardiol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1093\/eurjpc\/zwad243","author":"Galimzhanov","year":"2023","journal-title":"Eur J Prev Cardiol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1161\/circresaha.115.303633","volume":"118","author":"Lenneman","year":"2016","journal-title":"Circ Res"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"409","DOI":"10.3322\/caac.21731","volume":"72","author":"Miller","year":"2022","journal-title":"CA Cancer J Clin"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1093\/ije\/dyy262","volume":"48","author":"Sanderson","year":"2019","journal-title":"Int J Epidemiol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1007\/s10654-021-00757-1","volume":"36","author":"Carter","year":"2021","journal-title":"Eur J Epidemiol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1023006","DOI":"10.3389\/fcell.2022.1023006","volume":"10","author":"Gao","year":"2022","journal-title":"Front Cell Dev Biol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1111\/1756-185x.14624","volume":"26","author":"Quan","year":"2023","journal-title":"Int J Rheum Dis"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1614","DOI":"10.1001\/jama.2021.18236","volume":"326","author":"Skrivankova","year":"2021","journal-title":"JAMA"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1038\/nature24284","volume":"551","author":"Michailidou","year":"2017","journal-title":"Nature"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"1138149","DOI":"10.3389\/fendo.2023.1138149","volume":"14","author":"Tan","year":"2023","journal-title":"Front Endocrinol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1038\/ng.2385","volume":"44","author":"Scott","year":"2012","journal-title":"Nat Genet"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1038\/s41588-021-00931-x","volume":"53","author":"Sakaue","year":"2021","journal-title":"Nat Genet"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.1038\/ng.2797","volume":"45","author":"Willer","year":"2013","journal-title":"Nat Genet"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"11008","DOI":"10.1038\/s41598-017-10812-1","volume":"7","author":"Prins","year":"2017","journal-title":"Sci Rep"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1260","DOI":"10.1038\/s41588-021-00892-1","volume":"53","author":"Barton","year":"2021","journal-title":"Nat Genet"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1038\/s42003-020-01583-z","volume":"4","author":"Panyard","year":"2021","journal-title":"Commun Biol"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.63033","volume":"10","author":"Julkunen","year":"2021","journal-title":"Elife"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1007\/s10654-015-0011-z","volume":"30","author":"Burgess","year":"2015","journal-title":"Eur J Epidemiol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"3253","DOI":"10.1681\/asn.2016010098","volume":"27","author":"Sekula","year":"2016","journal-title":"J Am Soc Nephrol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"e32","DOI":"10.1017\/s2045796023000173","volume":"32","author":"Liu","year":"2023","journal-title":"Epidemiol Psychiatr Sci"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1007\/s10654-017-0255-x","volume":"32","author":"Burgess","year":"2017","journal-title":"Eur J Epidemiol"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1038\/s41588-018-0099-7","volume":"50","author":"Verbanck","year":"2018","journal-title":"Nat Genet"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.34408","volume":"7","author":"Hemani","year":"2018","journal-title":"Elife"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"16645","DOI":"10.1038\/srep16645","volume":"5","author":"Millard","year":"2015","journal-title":"Sci Rep"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"4014","DOI":"10.1200\/jco.2010.32.6462","volume":"29","author":"Colzani","year":"2011","journal-title":"J Clin Oncol"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"R64","DOI":"10.1186\/bcr2901","volume":"13","author":"Patnaik","year":"2011","journal-title":"Breast Cancer Res"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1097\/ede.0000000000000394","volume":"27","author":"Bradshaw","year":"2016","journal-title":"Epidemiology"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1093\/jnci\/djaa096","volume":"113","author":"Ramin","year":"2021","journal-title":"J Natl Cancer Inst"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1007\/s10549-011-1843-1","volume":"131","author":"Bardia","year":"2012","journal-title":"Breast Cancer Res Treat"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"2739","DOI":"10.1016\/j.jacc.2015.04.059","volume":"65","author":"Barac","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1093\/eurheartj\/ehab745","volume":"43","author":"Guha","year":"2022","journal-title":"Eur Heart J"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"1647","DOI":"10.1200\/jco.21.01736","volume":"40","author":"Greenlee","year":"2022","journal-title":"J Clin Oncol"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.canlet.2016.11.033","volume":"388","author":"Lu","year":"2017","journal-title":"Cancer Lett"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1186\/s12944-022-01747-2","volume":"21","author":"Georgoulis","year":"2022","journal-title":"Lipids Health Dis"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"155817","DOI":"10.1016\/j.metabol.2024.155817","volume":"154","author":"Chen","year":"2024","journal-title":"Metabolism"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/0304-3835(94)90008-6","volume":"82","author":"K\u00f6ko\u011flu","year":"1994","journal-title":"Cancer Lett"},{"key":"ref47","first-page":"581","volume":"23","author":"Kumar","year":"1991","journal-title":"Biochem Int"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"3065","DOI":"10.1002\/1097-0142(19871215)60:12<3065::aid-cncr2820601234>3.0.co;2-q","volume":"60","author":"Alexopoulos","year":"1987","journal-title":"Cancer"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"1219","DOI":"10.1515\/cclm.2007.263","volume":"45","author":"Chang","year":"2007","journal-title":"Clin Chem Lab Med"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.159577","volume":"7","author":"Sorokin","year":"2022","journal-title":"JCI Insight"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"e0148049","DOI":"10.1371\/journal.pone.0148049","volume":"11","author":"Sharma","year":"2016","journal-title":"PLoS One"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1016\/j.ijcard.2021.01.073","volume":"331","author":"Tan","year":"2021","journal-title":"Int J Cardiol"}],"container-title":["International Journal of Women's Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/97153","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/97153","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,9]],"date-time":"2024-11-09T06:05:14Z","timestamp":1731132314000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/causal-pathways-between-breast-cancer-and-cardiovascular-disease-throu-peer-reviewed-fulltext-article-IJWH"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":52,"URL":"https:\/\/doi.org\/10.2147\/ijwh.s483139","relation":{},"ISSN":["1179-1411"],"issn-type":[{"type":"electronic","value":"1179-1411"}],"subject":[],"published":{"date-parts":[[2024,11]]}}}