{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T17:56:25Z","timestamp":1790272585161,"version":"4.1.0"},"reference-count":261,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ITT"],"DOI":"10.2147\/itt.s485650","type":"journal-article","created":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T13:50:13Z","timestamp":1750686613000},"page":"605-629","source":"Crossref","is-referenced-by-count":10,"title":["Immunotargets and Therapy for Systemic Lupus Erythematosus"],"prefix":"10.2147","volume":"Volume 14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3696-1228","authenticated-orcid":true,"given":"Chi Chiu","family":"Mok","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2009","DOI":"10.1136\/annrheumdis-2017-211663","volume":"76","author":"Tektonidou","year":"2017","journal-title":"Ann Rheum Dis"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1177\/0961203317739129","volume":"27","author":"Mok","year":"2018","journal-title":"Lupus"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"552","DOI":"10.3389\/fmed.2020.00552","volume":"7","author":"Mok","year":"2020","journal-title":"Front Med"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1517\/14728214.2014.894018","volume":"19","author":"Mok","year":"2014","journal-title":"Expert Opin Emerg Drugs"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"2163","DOI":"10.1016\/S0140-6736(24)02381-X","volume":"404","author":"Hoi","year":"2024","journal-title":"Lancet Lond Engl"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1136\/jcp.56.7.481","volume":"56","author":"Mok","year":"2003","journal-title":"J Clin Pathol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"e004156","DOI":"10.1136\/rmdopen-2024-004156","volume":"10","author":"Mok","year":"2024","journal-title":"RMD Open"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"103648","DOI":"10.1016\/j.autrev.2024.103648","volume":"23","author":"Arnaud","year":"2024","journal-title":"Autoimmun Rev"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1501783","DOI":"10.3389\/fimmu.2024.1501783","volume":"15","author":"Zhou","year":"2024","journal-title":"Front Immunol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"i55","DOI":"10.1093\/rheumatology\/kew427","volume":"56","author":"Zharkova","year":"2017","journal-title":"Rheumatol Oxf Engl"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1080\/13543784.2019.1551358","volume":"28","author":"Mok","year":"2019","journal-title":"Expert Opin Investig Drugs"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"2110","DOI":"10.1056\/NEJMra1100359","volume":"365","author":"Tsokos","year":"2011","journal-title":"N Engl J Med"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"35","DOI":"10.3389\/fimmu.2016.00035","volume":"7","author":"Mahajan","year":"2016","journal-title":"Front Immunol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"649693","DOI":"10.3389\/fimmu.2021.649693","volume":"12","author":"Fresneda Alarcon","year":"2021","journal-title":"Front Immunol"},{"key":"ref15","first-page":"3522","volume":"188","author":"Leffler","year":"2012","journal-title":"J Immunol Baltim Md 1950"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"9813","DOI":"10.1073\/pnas.0909927107","volume":"107","author":"Hakkim","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1186\/ar2966","volume":"12","author":"Fransen","year":"2010","journal-title":"Arthritis Res Ther"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.jaut.2010.06.018","volume":"35","author":"Scheinecker","year":"2010","journal-title":"J Autoimmun"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"ii85","DOI":"10.1136\/annrheumdis-2012-202341","volume":"72 Suppl 2","author":"Fujio","year":"2013","journal-title":"Ann Rheum Dis"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1016\/j.immuni.2016.02.012","volume":"44","author":"Menon","year":"2016","journal-title":"Immunity"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1007\/s40265-023-01856-x","volume":"83","author":"Mok","year":"2023","journal-title":"Drugs"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1111\/1756-185X.12463","volume":"18","author":"Mok","year":"2015","journal-title":"Int J Rheum Dis"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"e149095","DOI":"10.1172\/JCI149095","volume":"131","author":"Atisha-Fregoso","year":"2021","journal-title":"J Clin Invest"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"2849","DOI":"10.1002\/art.38742","volume":"66","author":"Gao","year":"2014","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1146\/annurev-immunol-083122-044829","volume":"42","author":"Abeles","year":"2024","journal-title":"Annu Rev Immunol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1002\/art.27233","volume":"62","author":"Merrill","year":"2010","journal-title":"Arthritis Rheum"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1002\/art.34359","volume":"64","author":"Rovin","year":"2012","journal-title":"Arthritis Rheum"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1080\/1744666X.2017.1323635","volume":"13","author":"Mok","year":"2017","journal-title":"Expert Rev Clin Immunol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"S2","DOI":"10.1186\/ar3910","volume":"15","author":"Reddy","year":"2013","journal-title":"Arthritis Res Ther"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"2368","DOI":"10.1002\/art.38037","volume":"65","author":"Mysler","year":"2013","journal-title":"Arthritis Rheum"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1136\/annrheumdis-2021-220920","volume":"81","author":"Furie","year":"2022","journal-title":"Ann Rheum Dis"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"4393","DOI":"10.1182\/blood-2009-06-225979","volume":"115","author":"M\u00f6ssner","year":"2010","journal-title":"Blood"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1002\/art.41608","volume":"73","author":"Marinov","year":"2021","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/art.42734","volume":"76","author":"Rovin","year":"2023","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.1056\/NEJMoa2410965","volume":"392","author":"Furie","year":"2025","journal-title":"N Engl J Med"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"1280","DOI":"10.1136\/annrheumdis-2012-202844","volume":"72","author":"Condon","year":"2013","journal-title":"Ann Rheum Dis"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"3020","DOI":"10.1182\/blood-2012-12-473744","volume":"122","author":"Rossi","year":"2013","journal-title":"Blood"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1016\/j.autrev.2015.07.013","volume":"14","author":"D\u00f6rner","year":"2015","journal-title":"Autoimmun Rev"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"R74","DOI":"10.1186\/ar1942","volume":"8","author":"D\u00f6rner","year":"2006","journal-title":"Arthritis Res Ther"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1136\/ard.2007.075762","volume":"67","author":"Jacobi","year":"2008","journal-title":"Ann Rheum Dis"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1136\/annrheumdis-2012-202760","volume":"73","author":"Wallace","year":"2014","journal-title":"Ann Rheum Dis"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1002\/acr.22694","volume":"68","author":"Wallace","year":"2016","journal-title":"Arthritis Care Res"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1002\/art.39856","volume":"69","author":"Clowse","year":"2017","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref44","first-page":"4223","volume":"186","author":"Horton","year":"2011","journal-title":"J Immunol Baltim Md 1950"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"2185","DOI":"10.1002\/art.42652","volume":"75","author":"Merrill","year":"2023","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"2215","DOI":"10.1007\/s00277-020-04221-0","volume":"99","author":"Viardot","year":"2020","journal-title":"Ann Hematol"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"1593","DOI":"10.1038\/s41591-024-02964-1","volume":"30","author":"Bucci","year":"2024","journal-title":"Nat Med"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"114071","DOI":"10.1136\/annrheumdis-2020-eular.2700","volume":"204","author":"Subklewe","year":"2024","journal-title":"Eur J Cancer Oxf Engl"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1093\/cei\/uxae031","volume":"217","author":"Shah","year":"2024","journal-title":"Clin Exp Immunol"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1056\/NEJMoa2203478","volume":"387","author":"Moreau","year":"2022","journal-title":"N Engl J Med"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"864","DOI":"10.1056\/NEJMc2407150","volume":"391","author":"Alexander","year":"2024","journal-title":"N Engl J Med"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"1721","DOI":"10.3390\/vaccines11111721","volume":"11","author":"Mishra","year":"2023","journal-title":"Vaccines"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1056\/NEJMoa2308917","volume":"390","author":"M\u00fcller","year":"2024","journal-title":"N Engl J Med"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1038\/nrneph.2016.20","volume":"12","author":"Hiepe","year":"2016","journal-title":"Nat Rev Nephrol"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"e2149675","DOI":"10.1002\/eji.202149675","volume":"53","author":"Merino-Vico","year":"2023","journal-title":"Eur J Immunol"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"111646","DOI":"10.1016\/j.ejmech.2019.111646","volume":"182","author":"Xi","year":"2019","journal-title":"Eur J Med Chem"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"100994","DOI":"10.1016\/j.blre.2022.100994","volume":"57","author":"Fuchs","year":"2022","journal-title":"Blood Rev"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"1474","DOI":"10.1136\/annrheumdis-2014-206016","volume":"74","author":"Alexander","year":"2015","journal-title":"Ann Rheum Dis"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1177\/0961203316686703","volume":"26","author":"Zhang","year":"2017","journal-title":"Lupus"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"1573","DOI":"10.1002\/eji.201847492","volume":"48","author":"Alexander","year":"2018","journal-title":"Eur J Immunol"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1177\/0961203319896018","volume":"29","author":"Segarra","year":"2020","journal-title":"Lupus"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"756941","DOI":"10.3389\/fimmu.2021.756941","volume":"12","author":"Walhelm","year":"2021","journal-title":"Front Immunol"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"239","DOI":"10.2174\/156800911794519752","volume":"11","author":"Chen","year":"2011","journal-title":"Curr Cancer Drug Targets"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1124\/dmd.120.000307","volume":"49","author":"Fang","year":"2021","journal-title":"Drug Metab Dispos Biol Fate Chem"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1136\/annrheumdis-2020-eular.2700","volume":"79","author":"Furie","year":"2020","journal-title":"Ann Rheum Dis"},{"key":"ref66","unstructured":"Zetomipzomib (KZR-616), a first-in-class selective immunoproteasome inhibitor, demonstrated improvements in SLE\/LN disease measures and biomarkers in patients with highly active SLE or nephrotic range proteinuria in the open-label phase 1b\/2 MISSION study [Internet]. ACR Meeting Abstracts. Available from: https:\/\/acrabstracts.org\/abstract\/zetomipzomib-kzr-616-a-first-in-class-selective-immunoproteasome-inhibitor-demonstrated-improvements-in-sle-ln-disease-measures-and-biomarkers-in-patients-with-highly-active-sle-or-nephrotic-range\/. Accessed December 29, 2024."},{"key":"ref67","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/14789450.2022.2039631","author":"Richardson","year":"2022","journal-title":"Expert Rev Proteomics"},{"key":"ref68","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1016\/j.molimm.2011.03.006","volume":"48","author":"John","year":"2011","journal-title":"Mol Immunol"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1111\/bjh.12708","volume":"164","author":"Gandhi","year":"2014","journal-title":"Br J Haematol"},{"key":"ref70","first-page":"248","volume":"27","author":"Yuki","year":"2021","journal-title":"J Clin Rheumatol Pract Rep Rheum Musculoskelet Dis"},{"key":"ref71","doi-asserted-by":"publisher","first-page":"e293","DOI":"10.1093\/rheumatology\/kead116","volume":"62","author":"Wang","year":"2023","journal-title":"Rheumatol Oxf Engl"},{"key":"ref72","doi-asserted-by":"publisher","DOI":"10.7573\/dic.2021-9-8","volume":"11","author":"Malara","year":"2022","journal-title":"Drugs Context"},{"key":"ref73","doi-asserted-by":"publisher","first-page":"R265","DOI":"10.1186\/ar4111","volume":"14","author":"Cort\u00e9s-Hern\u00e1ndez","year":"2012","journal-title":"Arthritis Res Ther"},{"key":"ref74","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/j.jaad.2013.11.007","volume":"70","author":"Okon","year":"2014","journal-title":"J Am Acad Dermatol"},{"key":"ref75","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1159\/000508672","volume":"236","author":"Domingo","year":"2020","journal-title":"Dermatol Basel Switz"},{"key":"ref76","doi-asserted-by":"publisher","first-page":"980","DOI":"10.1001\/jamaoncol.2016.3350","volume":"3","author":"Li","year":"2017","journal-title":"JAMA Oncol"},{"key":"ref77","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1021\/acs.jmedchem.6b01921","volume":"61","author":"Matyskiela","year":"2018","journal-title":"J Med Chem"},{"key":"ref78","doi-asserted-by":"publisher","first-page":"1136","DOI":"10.1136\/annrheumdis-2022-222212","volume":"81","author":"Lipsky","year":"2022","journal-title":"Ann Rheum Dis"},{"key":"ref79","doi-asserted-by":"publisher","first-page":"e000581","DOI":"10.1136\/lupus-2021-000581","volume":"9","author":"Furie","year":"2022","journal-title":"Lupus Sci Med"},{"key":"ref80","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.1056\/NEJMoa2106535","volume":"386","author":"Merrill","year":"2022","journal-title":"N Engl J Med"},{"key":"ref81","first-page":"3044","volume":"S0190-9622","author":"Werth","year":"2024","journal-title":"J Am Acad Dermatol"},{"key":"ref82","doi-asserted-by":"publisher","first-page":"1582","DOI":"10.1016\/S1470-2045(21)00466-6","volume":"22","author":"Facon","year":"2021","journal-title":"Lancet Oncol"},{"key":"ref83","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1056\/NEJMoa2023325","volume":"383","author":"Ostendorf","year":"2020","journal-title":"N Engl J Med"},{"key":"ref84","doi-asserted-by":"publisher","first-page":"2041","DOI":"10.1038\/s41591-023-02479-1","volume":"29","author":"Roccatello","year":"2023","journal-title":"Nat Med"},{"key":"ref85","doi-asserted-by":"publisher","first-page":"2635","DOI":"10.1016\/j.ekir.2024.06.018","volume":"9","author":"Rovin","journal-title":"Kidney Int Rep"},{"key":"ref86","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1126\/science.285.5425.260","volume":"285","author":"Moore","year":"1999","journal-title":"Science"},{"key":"ref87","doi-asserted-by":"publisher","first-page":"2453","DOI":"10.1002\/art.23678","volume":"58","author":"Petri","year":"2008","journal-title":"Arthritis Rheum"},{"key":"ref88","doi-asserted-by":"publisher","first-page":"R6","DOI":"10.1186\/ar1855","volume":"8","author":"Collins","year":"2006","journal-title":"Arthritis Res Ther"},{"key":"ref89","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1002\/iub.1046","volume":"64","author":"Fairfax","year":"2012","journal-title":"IUBMB Life"},{"key":"ref90","doi-asserted-by":"publisher","first-page":"2435","DOI":"10.2165\/11208440-000000000-00000","volume":"71","author":"Burness","year":"2011","journal-title":"Drugs"},{"key":"ref91","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1016\/S0140-6736(10)61354-2","volume":"377","author":"Navarra","year":"2011","journal-title":"Lancet Lond Engl"},{"key":"ref92","doi-asserted-by":"publisher","first-page":"3918","DOI":"10.1002\/art.30613","volume":"63","author":"Furie","year":"2011","journal-title":"Arthritis Rheum"},{"key":"ref93","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1136\/annrheumdis-2017-211631","volume":"77","author":"Zhang","year":"2018","journal-title":"Ann Rheum Dis"},{"key":"ref94","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.1002\/art.40511","volume":"70","author":"Doria","year":"2018","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref95","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1093\/rheumatology\/kez279","volume":"59","author":"van Vollenhoven","year":"2020","journal-title":"Rheumatol Oxf Engl"},{"key":"ref96","doi-asserted-by":"publisher","first-page":"1134","DOI":"10.1016\/j.clinthera.2016.02.022","volume":"38","author":"Wei","year":"2016","journal-title":"Clin Ther"},{"key":"ref97","doi-asserted-by":"publisher","first-page":"2184","DOI":"10.1002\/art.39682","volume":"68","author":"van Vollenhoven","year":"2016","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref98","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1093\/rheumatology\/kead253","volume":"63","author":"Gomez","year":"2024","journal-title":"Rheumatol Oxf Engl"},{"key":"ref99","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1056\/NEJMoa2001180","volume":"383","author":"Furie","year":"2020","journal-title":"N Engl J Med"},{"key":"ref100","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1053\/j.ajkd.2022.06.013","volume":"81","author":"Yu","year":"2023","journal-title":"Am J Kidney Dis off J Natl Kidney Found"},{"key":"ref101","first-page":"2733","volume":"38","author":"Anders","year":"2023","journal-title":"Nephrol Dial Transplant off Publ Eur Dial Transpl Assoc - Eur Ren Assoc"},{"key":"ref102","doi-asserted-by":"publisher","first-page":"1620","DOI":"10.2215\/CJN.02520322","volume":"17","author":"Furie","year":"2022","journal-title":"Clin J Am Soc Nephrol CJASN"},{"key":"ref103","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1016\/j.kint.2021.08.027","volume":"101","author":"Rovin","year":"2022","journal-title":"Kidney Int"},{"key":"ref104","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1097\/BOR.0b013e328344c15e","volume":"23","author":"Stohl","year":"2011","journal-title":"Curr Opin Rheumatol"},{"key":"ref105","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1136\/annrheumdis-2015-207653","volume":"75","author":"Isenberg","year":"2016","journal-title":"Ann Rheum Dis"},{"key":"ref106","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1136\/annrheumdis-2015-207654","volume":"75","author":"Merrill","year":"2016","journal-title":"Ann Rheum Dis"},{"key":"ref107","doi-asserted-by":"publisher","first-page":"1597","DOI":"10.1177\/0961203316650734","volume":"25","author":"Rovin","year":"2016","journal-title":"Lupus"},{"key":"ref108","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1186\/s13075-015-0741-z","volume":"17","author":"Stohl","year":"2015","journal-title":"Arthritis Res Ther"},{"key":"ref109","doi-asserted-by":"publisher","first-page":"1667","DOI":"10.1136\/annrheumdis-2013-205144","volume":"74","author":"Furie","year":"2015","journal-title":"Ann Rheum Dis"},{"key":"ref110","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1136\/annrheumdis-2018-213032","volume":"77","author":"Merrill","year":"2018","journal-title":"Ann Rheum Dis"},{"key":"ref111","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1186\/ar2976","volume":"12","author":"Stohl","year":"2010","journal-title":"Arthritis Res Ther"},{"key":"ref112","doi-asserted-by":"publisher","first-page":"4142","DOI":"10.1002\/art.23047","volume":"56","author":"Dall\u2019Era","year":"2007","journal-title":"Arthritis Rheum"},{"key":"ref113","doi-asserted-by":"publisher","first-page":"R33","DOI":"10.1186\/ar3738","volume":"14","author":"Ginzler","year":"2012","journal-title":"Arthritis Res Ther"},{"key":"ref114","doi-asserted-by":"publisher","first-page":"2006","DOI":"10.1136\/annrheumdis-2013-205067","volume":"74","author":"Isenberg","year":"2015","journal-title":"Ann Rheum Dis"},{"key":"ref115","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1002\/art.39809","volume":"69","author":"Gordon","year":"2017","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref116","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1002\/art.40360","volume":"70","author":"Merrill","year":"2018","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref117","first-page":"105704","volume":"159","author":"Yao","year":"2021","journal-title":"Eur J Pharm Sci off J Eur Fed Pharm Sci"},{"key":"ref118","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1136\/ard-2023-224854","volume":"83","author":"Wu","year":"2024","journal-title":"Ann Rheum Dis"},{"key":"ref119","doi-asserted-by":"publisher","first-page":"2672","DOI":"10.1002\/art.38074","volume":"65","author":"Carter","year":"2013","journal-title":"Arthritis Rheum"},{"key":"ref120","first-page":"1474","volume":"36","author":"Kraaij","year":"2021","journal-title":"Nephrol Dial Transplant off Publ Eur Dial Transpl Assoc - Eur Ren Assoc"},{"key":"ref121","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1002\/art.41466","volume":"73","author":"Atisha-Fregoso","year":"2021","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref122","doi-asserted-by":"publisher","first-page":"1647","DOI":"10.7326\/M21-2078","volume":"174","author":"Shipa","year":"2021","journal-title":"Ann Intern Med"},{"key":"ref123","doi-asserted-by":"publisher","first-page":"1502","DOI":"10.1136\/ard-2024-225686","volume":"83","author":"Aranow","year":"2024","journal-title":"Ann Rheum Dis"},{"key":"ref124","doi-asserted-by":"publisher","first-page":"102364","DOI":"10.1016\/j.jaut.2019.102364","volume":"110","author":"Mavragani","year":"2020","journal-title":"J Autoimmun"},{"key":"ref125","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1002\/acr2.11487","volume":"4","author":"Abuqayyas","year":"2022","journal-title":"ACR Open Rheumatol"},{"key":"ref126","doi-asserted-by":"publisher","first-page":"1605","DOI":"10.1007\/s40265-021-01592-0","volume":"81","author":"Neys","year":"2021","journal-title":"Drugs"},{"key":"ref127","doi-asserted-by":"crossref","first-page":"4907","DOI":"10.3390\/molecules26164907","volume":"26","author":"Zhang","year":"2021","journal-title":"Mol"},{"key":"ref128","doi-asserted-by":"publisher","first-page":"95","DOI":"10.3389\/fimmu.2019.00095","volume":"10","author":"Rip","year":"2019","journal-title":"Front Immunol"},{"key":"ref129","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1007\/s10067-017-3717-3","volume":"37","author":"Kong","year":"2018","journal-title":"Clin Rheumatol"},{"key":"ref130","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1002\/acr2.11511","volume":"5","author":"Wallace","year":"2023","journal-title":"ACR Open Rheumatol"},{"key":"ref131","doi-asserted-by":"publisher","first-page":"1835","DOI":"10.1002\/art.41811","volume":"73","author":"Isenberg","year":"2021","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref132","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1136\/annrheumdis-2022-eular.5086a","volume":"81","author":"Li","year":"2022","journal-title":"Ann Rheum Dis"},{"key":"ref133","doi-asserted-by":"publisher","first-page":"1302714","DOI":"10.3389\/fnins.2024.1302714","volume":"18","author":"Leu","year":"2024","journal-title":"Front Neurosci"},{"key":"ref134","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1136\/annrheumdis-2024-eular.LBA90","volume":"83","author":"Gottenberg","year":"2024","journal-title":"Ann Rheum Dis"},{"key":"ref135","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/S1474-4422(24)00498-8","volume":"24","author":"Antozzi","year":"2025","journal-title":"Lancet Neurol"},{"key":"ref136","doi-asserted-by":"publisher","first-page":"2351","DOI":"10.1002\/ajh.27487","volume":"99","author":"Jacobs","year":"2024","journal-title":"Am J Hematol"},{"key":"ref137","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.berh.2017.09.010","volume":"31","author":"Mok","year":"2017","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"ref138","first-page":"1561","volume":"31","author":"Mok","year":"2016","journal-title":"Nephrol Dial Transplant off Publ Eur Dial Transpl Assoc - Eur Ren Assoc"},{"key":"ref139","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1136\/ard.62.9.799","volume":"62","author":"Mok","year":"2003","journal-title":"Ann Rheum Dis"},{"key":"ref140","doi-asserted-by":"publisher","first-page":"1070","DOI":"10.1136\/annrheumdis-2020-217178","volume":"79","author":"Mok","year":"2020","journal-title":"Ann Rheum Dis"},{"key":"ref141","doi-asserted-by":"publisher","first-page":"e224492","DOI":"10.1001\/jamanetworkopen.2022.4492","volume":"5","author":"Zheng","year":"2022","journal-title":"JAMA Network Open"},{"key":"ref142","doi-asserted-by":"publisher","first-page":"18","DOI":"10.7326\/M14-1030","volume":"162","author":"Liu","year":"2015","journal-title":"Ann Intern Med"},{"key":"ref143","doi-asserted-by":"publisher","first-page":"3671","DOI":"10.1681\/ASN.2017030263","volume":"28","author":"Zhang","year":"2017","journal-title":"J Am Soc Nephrol JASN"},{"key":"ref144","doi-asserted-by":"publisher","first-page":"1135","DOI":"10.1177\/0961203313502864","volume":"22","author":"Mok","year":"2013","journal-title":"Lupus"},{"key":"ref145","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1177\/0961203310365714","volume":"19","author":"Lanata","year":"2010","journal-title":"Lupus"},{"key":"ref146","doi-asserted-by":"publisher","first-page":"1192","DOI":"10.1177\/0961203314540353","volume":"23","author":"Webster","year":"2014","journal-title":"Lupus"},{"key":"ref147","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1038\/nrrheum.2015.174","volume":"12","author":"Mok","year":"2016","journal-title":"Nat Rev Rheumatol"},{"key":"ref148","doi-asserted-by":"publisher","first-page":"613","DOI":"10.3899\/jrheum.2023-0210","volume":"51","author":"Takeuchi","year":"2024","journal-title":"J Rheumatol"},{"key":"ref149","doi-asserted-by":"publisher","first-page":"e70021","DOI":"10.1111\/1756-185X.70021","volume":"28","author":"Mok","year":"2025","journal-title":"Int J Rheum Dis"},{"key":"ref150","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1080\/17512433.2022.2092470","volume":"15","author":"van Gelder","year":"2022","journal-title":"Expert Rev Clin Pharmacol"},{"key":"ref151","doi-asserted-by":"publisher","first-page":"2070","DOI":"10.1016\/S0140-6736(21)00578-X","volume":"397","author":"Rovin","year":"2021","journal-title":"Lancet Lond Engl"},{"key":"ref152","doi-asserted-by":"publisher","first-page":"2027","DOI":"10.1016\/S0140-6736(21)00663-2","volume":"397","author":"Mok","year":"2021","journal-title":"Lancet Lond Engl"},{"key":"ref153","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.kint.2023.09.001","volume":"105","author":"Rovin","year":"2024","journal-title":"Kidney Int"},{"key":"ref154","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1136\/annrheumdis-2020-216924","volume":"79","author":"Fanouriakis","year":"2020","journal-title":"Ann Rheum Dis"},{"key":"ref155","doi-asserted-by":"publisher","first-page":"3830","DOI":"10.1093\/rheumatology\/keac037","volume":"61","author":"Mao","year":"2022","journal-title":"Rheumatol Oxf Engl"},{"key":"ref156","doi-asserted-by":"publisher","first-page":"S32","DOI":"10.1097\/TP.0000000000001729","volume":"102","author":"Ma","year":"2018","journal-title":"Transplantation"},{"key":"ref157","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.1016\/S0140-6736(18)30485-9","volume":"391","author":"Lai","year":"2018","journal-title":"Lancet Lond Engl"},{"key":"ref158","doi-asserted-by":"publisher","first-page":"82","DOI":"10.3389\/fphar.2019.00082","volume":"10","author":"Eriksson","year":"2019","journal-title":"Front Pharmacol"},{"key":"ref159","doi-asserted-by":"publisher","first-page":"1759720X20953336","DOI":"10.1177\/1759720X20953336","volume":"12","author":"Peng","year":"2020","journal-title":"Ther Adv Musculoskelet Dis"},{"key":"ref160","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1016\/j.semarthrit.2020.07.006","volume":"50","author":"Ji","year":"2020","journal-title":"Semin Arthritis Rheum"},{"key":"ref161","doi-asserted-by":"publisher","first-page":"1559","DOI":"10.1517\/14712598.2012.721773","volume":"12","author":"Mok","year":"2012","journal-title":"Expert Opin Biol Ther"},{"key":"ref162","doi-asserted-by":"publisher","first-page":"3077","DOI":"10.1002\/art.27601","volume":"62","author":"Merrill","year":"2010","journal-title":"Arthritis Rheum"},{"key":"ref163","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1002\/art.38260","volume":"66","author":"Furie","year":"2014","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref164","doi-asserted-by":"crossref","unstructured":"ACCESS Trial Group. Treatment of lupus nephritis with abatacept: the abatacept and cyclophosphamide combination efficacy and safety study. Arthritis Rheumatol Hoboken NJ. 2014;66(11):3096\u20133104. doi:10.1002\/art.38790","DOI":"10.1002\/art.38790"},{"key":"ref165","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1191\/0961203304lu1030oa","volume":"13","author":"Yazdany","year":"2004","journal-title":"Lupus"},{"key":"ref166","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/s00296-009-0933-4","volume":"30","author":"Manea","year":"2009","journal-title":"Rheumatol Int"},{"key":"ref167","doi-asserted-by":"publisher","first-page":"102668","DOI":"10.1016\/j.autrev.2020.102668","volume":"19","author":"Ramanujam","year":"2020","journal-title":"Autoimmun Rev"},{"key":"ref168","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1002\/art.10856","volume":"48","author":"Boumpas","year":"2003","journal-title":"Arthritis Rheum"},{"key":"ref169","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1177\/0961203315574558","volume":"24","author":"Tocoian","year":"2015","journal-title":"Lupus"},{"key":"ref170","doi-asserted-by":"publisher","first-page":"5397","DOI":"10.1093\/rheumatology\/keab381","volume":"60","author":"Furie","year":"2021","journal-title":"Rheumatol Oxf Engl"},{"key":"ref171","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.1111\/j.1600-0560.2010.01587.x","volume":"37","author":"Tomasini","year":"2010","journal-title":"J Cutan Pathol"},{"key":"ref172","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1002\/art.23186","volume":"58","author":"Tucci","year":"2008","journal-title":"Arthritis Rheum"},{"key":"ref173","doi-asserted-by":"publisher","first-page":"15","DOI":"10.2217\/imt-2023-0086","volume":"16","author":"Cho","year":"2024","journal-title":"Immunotherapy"},{"key":"ref174","doi-asserted-by":"publisher","first-page":"102856","DOI":"10.1016\/j.jaut.2022.102856","volume":"132","author":"Liu","year":"2022","journal-title":"J Autoimmun"},{"key":"ref175","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1056\/NEJMoa2118025","volume":"387","author":"Furie","year":"2022","journal-title":"N Engl J Med"},{"key":"ref176","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1056\/NEJMoa2118024","volume":"387","author":"Werth","year":"2022","journal-title":"N Engl J Med"},{"key":"ref177","doi-asserted-by":"publisher","first-page":"eabf8442","DOI":"10.1126\/scitranslmed.abf8442","volume":"13","author":"Karnell","year":"2021","journal-title":"Sci Transl Med"},{"key":"ref178","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1136\/annrheumdis-2024-eular.1540","volume":"83","author":"Baribaud","year":"2024","journal-title":"Ann Rheum Dis"},{"key":"ref179","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1089\/jir.2011.0029","volume":"31","author":"Apostolidis","year":"2011","journal-title":"J Interferon Cytokine Res off J Int Soc Interferon Cytokine Res"},{"key":"ref180","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1186\/ar3349","volume":"13","author":"Jacob","year":"2011","journal-title":"Arthritis Res Ther"},{"key":"ref181","doi-asserted-by":"publisher","first-page":"347141","DOI":"10.1155\/2012\/347141","volume":"2012","author":"Su","year":"2012","journal-title":"J Biomed Biotechnol"},{"key":"ref182","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1186\/ar625","volume":"5","author":"R\u00f6nnblom","year":"2003","journal-title":"Arthritis Res Ther"},{"key":"ref183","doi-asserted-by":"publisher","first-page":"1692","DOI":"10.1136\/ard.2004.033753","volume":"64","author":"Dall\u2019era","year":"2005","journal-title":"Ann Rheum Dis"},{"key":"ref184","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1136\/ard.2007.074765","volume":"67","author":"Nikpour","year":"2008","journal-title":"Ann Rheum Dis"},{"key":"ref185","doi-asserted-by":"publisher","first-page":"2951","DOI":"10.1002\/art.22044","volume":"54","author":"Feng","year":"2006","journal-title":"Arthritis Rheum"},{"key":"ref186","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.coi.2020.10.014","volume":"67","author":"Postal","year":"2020","journal-title":"Curr Opin Immunol"},{"key":"ref187","doi-asserted-by":"publisher","first-page":"3666","DOI":"10.1002\/art.34632","volume":"64","author":"McBride","year":"2012","journal-title":"Arthritis Rheum"},{"key":"ref188","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1136\/annrheumdis-2014-206090","volume":"75","author":"Kalunian","year":"2016","journal-title":"Ann Rheum Dis"},{"key":"ref189","doi-asserted-by":"publisher","first-page":"1909","DOI":"10.1136\/annrheumdis-2015-208562","volume":"75","author":"Khamashta","year":"2016","journal-title":"Ann Rheum Dis"},{"key":"ref190","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1177\/0961203316652495","volume":"25","author":"Kalunian","year":"2016","journal-title":"Lupus"},{"key":"ref191","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1002\/art.39962","volume":"69","author":"Furie","year":"2017","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref192","doi-asserted-by":"publisher","first-page":"e208","DOI":"10.1016\/S2665-9913(19)30076-1","volume":"1","author":"Furie","year":"2019","journal-title":"Lancet Rheumatol"},{"key":"ref193","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1056\/NEJMoa1912196","volume":"382","author":"Morand","year":"2020","journal-title":"N Engl J Med"},{"key":"ref194","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1136\/ard-2022-222748","volume":"82","author":"Morand","year":"2023","journal-title":"Ann Rheum Dis"},{"key":"ref195","doi-asserted-by":"publisher","first-page":"1526","DOI":"10.1093\/rheumatology\/keac491","volume":"62","author":"Bruce","year":"2023","journal-title":"Rheumatol Oxf Engl"},{"key":"ref196","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1136\/annrheumdis-2021-221425","volume":"81","author":"Vital","year":"2022","journal-title":"Ann Rheum Dis"},{"key":"ref197","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/art.42392","volume":"75","author":"Kalunian","year":"2023","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref198","doi-asserted-by":"publisher","first-page":"e000464","DOI":"10.1136\/lupus-2020-000464","volume":"8","author":"Tummala","year":"2021","journal-title":"Lupus Sci Med"},{"key":"ref199","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1136\/annrheumdis-2021-221478","volume":"81","author":"Jayne","year":"2022","journal-title":"Ann Rheum Dis"},{"key":"ref200","doi-asserted-by":"publisher","first-page":"e000910","DOI":"10.1136\/lupus-2023-000910","volume":"10","author":"Jayne","year":"2023","journal-title":"Lupus Sci Med"},{"key":"ref201","doi-asserted-by":"publisher","first-page":"1138","DOI":"10.1136\/ard.2010.141101","volume":"70","author":"Mathian","year":"2011","journal-title":"Ann Rheum Dis"},{"key":"ref202","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1002\/art.37785","volume":"65","author":"Lauwerys","year":"2013","journal-title":"Arthritis Rheum"},{"key":"ref203","doi-asserted-by":"publisher","first-page":"1901","DOI":"10.1093\/rheumatology\/kew262","volume":"55","author":"Ducreux","year":"2016","journal-title":"Rheumatol Oxf Engl"},{"key":"ref204","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1007\/s10875-007-9104-0","volume":"27","author":"Chun","year":"2007","journal-title":"J Clin Immunol"},{"key":"ref205","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1002\/art.27221","volume":"62","author":"Illei","year":"2010","journal-title":"Arthritis Rheum"},{"key":"ref206","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1136\/annrheumdis-2012-201310","volume":"72","author":"Shirota","year":"2013","journal-title":"Ann Rheum Dis"},{"key":"ref207","doi-asserted-by":"publisher","first-page":"2661","DOI":"10.1002\/art.38091","volume":"65","author":"Szepietowski","year":"2013","journal-title":"Arthritis Rheum"},{"key":"ref208","doi-asserted-by":"publisher","first-page":"2174","DOI":"10.1002\/art.39722","volume":"68","author":"Rovin","year":"2016","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref209","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1517\/14728222.9.6.1123","volume":"9","author":"Kreymborg","year":"2005","journal-title":"Expert Opin Ther Targets"},{"key":"ref210","first-page":"903","volume":"199","author":"Dai","year":"2017","journal-title":"J Immunol Baltim Md 1950"},{"key":"ref211","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1177\/0961203313498799","volume":"22","author":"Qiu","year":"2013","journal-title":"Lupus"},{"key":"ref212","doi-asserted-by":"publisher","first-page":"220","DOI":"10.3109\/s10165-007-0568-9","volume":"17","author":"Huang","year":"2007","journal-title":"Mod Rheumatol"},{"key":"ref213","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1002\/art.41179","volume":"72","author":"van Vollenhoven","year":"2020","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref214","doi-asserted-by":"publisher","first-page":"1330","DOI":"10.1016\/S0140-6736(18)32167-6","volume":"392","author":"van Vollenhoven","year":"2018","journal-title":"Lancet Lond Engl"},{"key":"ref215","doi-asserted-by":"publisher","first-page":"1556","DOI":"10.1136\/ard-2022-222858","volume":"81","author":"van Vollenhoven","year":"2022","journal-title":"Ann Rheum Dis"},{"key":"ref216","doi-asserted-by":"publisher","first-page":"2731","DOI":"10.1093\/rheumatology\/keae647","volume":"64","author":"Anders","year":"2025","journal-title":"Rheumatol Oxf Engl"},{"key":"ref217","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1080\/08830185.2023.2274574","volume":"43","author":"Zhang","year":"2024","journal-title":"Int Rev Immunol"},{"key":"ref218","doi-asserted-by":"publisher","first-page":"e1165","DOI":"10.1002\/iid3.1165","volume":"12","author":"Su","year":"2024","journal-title":"Immun Inflamm Dis"},{"key":"ref219","doi-asserted-by":"publisher","first-page":"e68748","DOI":"10.7759\/cureus.68748","volume":"16","author":"Farooq","year":"2024","journal-title":"Cureus"},{"key":"ref220","first-page":"1053","volume":"213","author":"Santana","year":"2024","journal-title":"J Immunol Baltim Md 1950"},{"key":"ref221","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1136\/ard-2022-222501","volume":"81","author":"Humrich","year":"2022","journal-title":"Ann Rheum Dis"},{"key":"ref222","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1136\/annrheumdis-2019-215396","volume":"79","author":"He","year":"2020","journal-title":"Ann Rheum Dis"},{"key":"ref223","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/S0140-6736(18)31363-1","volume":"392","author":"Wallace","year":"2018","journal-title":"Lancet Lond Engl"},{"key":"ref224","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1186\/s13075-022-02794-x","volume":"24","author":"D\u00f6rner","year":"2022","journal-title":"Arthritis Res Ther"},{"key":"ref225","doi-asserted-by":"publisher","first-page":"e000424","DOI":"10.1136\/lupus-2020-000424","volume":"7","author":"D\u00f6rner","year":"2020","journal-title":"Lupus Sci Med"},{"key":"ref226","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1016\/S0140-6736(22)02607-1","volume":"401","author":"Morand","year":"2023","journal-title":"Lancet Lond Engl"},{"key":"ref227","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1016\/S0140-6736(22)02546-6","volume":"401","author":"Petri","year":"2023","journal-title":"Lancet Lond Engl"},{"key":"ref228","doi-asserted-by":"publisher","first-page":"e15082","DOI":"10.1111\/1756-185X.15082","volume":"27","author":"Mok","year":"2024","journal-title":"Int J Rheum Dis"},{"key":"ref229","first-page":"1518","volume":"76","author":"Merrill","year":"2024","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref230","doi-asserted-by":"publisher","first-page":"103649","DOI":"10.1016\/j.autrev.2024.103649","volume":"23","author":"Ramakrishna","year":"2024","journal-title":"Autoimmun Rev"},{"key":"ref231","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1002\/art.42391","volume":"75","author":"Morand","year":"2023","journal-title":"Arthritis Rheumatol Hoboken NJ"},{"key":"ref232","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.clim.2013.02.014","volume":"148","author":"Barilla-Labarca","year":"2013","journal-title":"Clin Immunol Orlando Fla"},{"key":"ref233","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1191\/0961203303lu1021oa","volume":"13","author":"Rother","year":"2004","journal-title":"Lupus"},{"key":"ref234","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1186\/s12882-020-01888-5","volume":"21","author":"Wright","year":"2020","journal-title":"BMC Nephrol"},{"key":"ref235","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1053\/j.ajkd.2014.07.031","volume":"65","author":"El-Husseini","year":"2015","journal-title":"Am J Kidney Dis off J Natl Kidney Found"},{"key":"ref236","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1007\/s40265-024-02009-4","volume":"84","author":"Syed","year":"2024","journal-title":"Drugs"},{"key":"ref237","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1007\/s40265-024-02094-5","volume":"84","author":"Kitsou","year":"2024","journal-title":"Drugs"},{"key":"ref238","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1007\/s40265-021-01528-8","volume":"81","author":"P\u00e9rez-Jeldres","year":"2021","journal-title":"Drugs"},{"key":"ref239","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1007\/s40265-016-0603-2","volume":"76","author":"Tsai","year":"2016","journal-title":"Drugs"},{"key":"ref240","doi-asserted-by":"publisher","first-page":"113341","DOI":"10.1016\/j.biopha.2022.113341","volume":"153","author":"Chen","year":"2022","journal-title":"Biomed Pharmacother Biomedecine Pharmacother"},{"key":"ref241","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1038\/s41584-022-00784-6","volume":"18","author":"Burg","year":"2022","journal-title":"Nat Rev Rheumatol"},{"key":"ref242","doi-asserted-by":"publisher","first-page":"1902","DOI":"10.1177\/0961203320966385","volume":"29","author":"Tanaka","year":"2020","journal-title":"Lupus"},{"key":"ref243","doi-asserted-by":"publisher","first-page":"e000354","DOI":"10.1136\/lupus-2019-000354","volume":"6","author":"Hermann","year":"2019","journal-title":"Lupus Sci Med"},{"key":"ref244","doi-asserted-by":"publisher","first-page":"e21","DOI":"10.1016\/S2665-9913(24)00246-7","volume":"7","author":"Askanase","year":"2025","journal-title":"Lancet Rheumatol"},{"key":"ref245","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1136\/ard-2024-226547","volume":"84","author":"Suffiotti","year":"2025","journal-title":"Ann Rheum Dis"},{"key":"ref246","first-page":"257","volume":"28","author":"Furie","year":"2001","journal-title":"J Rheumatol"},{"key":"ref247","doi-asserted-by":"publisher","first-page":"2470","DOI":"10.1002\/art.23673","volume":"58","author":"Cardiel","year":"2008","journal-title":"Arthritis Rheum"},{"key":"ref248","doi-asserted-by":"publisher","first-page":"1501","DOI":"10.1517\/14656560902946419","volume":"10","author":"Horowitz","year":"2009","journal-title":"Expert Opin Pharmacother"},{"key":"ref249","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.humimm.2009.01.018","volume":"70","author":"Sthoeger","year":"2009","journal-title":"Hum Immunol"},{"key":"ref250","doi-asserted-by":"publisher","first-page":"e60394","DOI":"10.1371\/journal.pone.0060394","volume":"8","author":"Sthoeger","year":"2013","journal-title":"PLoS One"},{"key":"ref251","doi-asserted-by":"publisher","first-page":"e000104","DOI":"10.1136\/lupus-2015-000104","volume":"2","author":"Urowitz","year":"2015","journal-title":"Lupus Sci Med"},{"key":"ref252","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.jaut.2012.05.016","volume":"39","author":"Schall","year":"2012","journal-title":"J Autoimmun"},{"key":"ref253","doi-asserted-by":"publisher","first-page":"R111","DOI":"10.1186\/ar2317","volume":"9","author":"Monneaux","year":"2007","journal-title":"Arthritis Res Ther"},{"key":"ref254","doi-asserted-by":"publisher","first-page":"1830","DOI":"10.1136\/annrheumdis-2012-202460","volume":"72","author":"Zimmer","year":"2013","journal-title":"Ann Rheum Dis"},{"key":"ref255","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1136\/ard-2022-222839","volume":"82","author":"Lorenzo-Vizcaya","year":"2023","journal-title":"Ann Rheum Dis"},{"key":"ref256","doi-asserted-by":"publisher","first-page":"A164","DOI":"10.1136\/annrheumdis-2013-eular.528","volume":"72","author":"Jayne","year":"2013","journal-title":"Ann Rheum Dis"},{"key":"ref257","doi-asserted-by":"publisher","first-page":"9577","DOI":"10.3390\/ijms25179577","volume":"25","author":"Mok","year":"2024","journal-title":"Int J Mol Sci"},{"key":"ref258","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1186\/s13075-021-02454-6","volume":"23","author":"Hamidou","year":"2021","journal-title":"Arthritis Res Ther"},{"key":"ref259","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1080\/1744666X.2023.2192927","volume":"19","author":"Mok","year":"2023","journal-title":"Expert Rev Clin Immunol"},{"key":"ref260","doi-asserted-by":"publisher","first-page":"31","DOI":"10.2478\/rir-2020-0005","volume":"1","author":"Mok","year":"2020","journal-title":"Rheumatol Immunol Res"},{"key":"ref261","doi-asserted-by":"publisher","first-page":"2","DOI":"10.2174\/1573397114666180406100857","volume":"15","author":"Mok","year":"2019","journal-title":"Curr Rheumatol Rev"}],"container-title":["ImmunoTargets and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/104146","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/104146","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T13:50:16Z","timestamp":1750686616000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/immunotargets-and-therapy-for-systemic-lupus-erythematosus-peer-reviewed-fulltext-article-ITT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":261,"URL":"https:\/\/doi.org\/10.2147\/itt.s485650","relation":{},"ISSN":["2253-1556"],"issn-type":[{"value":"2253-1556","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]}}}