{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T17:05:02Z","timestamp":1782320702591,"version":"3.54.5"},"reference-count":36,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ITT"],"DOI":"10.2147\/itt.s500723","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T07:50:10Z","timestamp":1737359410000},"page":"25-33","source":"Crossref","is-referenced-by-count":3,"title":["Increased Co-Expression of PD-L1 and CTLA-4 Predicts Poor Overall Survival in Patients with Acute Myeloid Leukemia Following Allogeneic Hematopoietic Stem Cell Transplantation"],"prefix":"10.2147","volume":"Volume 14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3733-9174","authenticated-orcid":true,"given":"Cunte","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kangjie","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunqing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caixia","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0974-4036","authenticated-orcid":true,"given":"Yangqiu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,1]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1182\/blood.2022015522","volume":"140","author":"Gournay","year":"2022","journal-title":"Blood"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"229","DOI":"10.7326\/M19-2936","volume":"172","author":"McDonald","year":"2020","journal-title":"Ann Intern Med"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"e00207","DOI":"10.1097\/BS9.0000000000000207","volume":"6","author":"Deng","year":"2024","journal-title":"Blood Sci"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1186\/s13045-020-00853-x","volume":"13","author":"Chen","year":"2020","journal-title":"J Hematol Oncol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"463","DOI":"10.21147\/j.issn.1000-9604.2017.05.11","volume":"29","author":"Tan","year":"2017","journal-title":"Chin J Cancer Res"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.clim.2018.02.009","volume":"190","author":"Liu","year":"2018","journal-title":"Clin Immunol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"2201507","DOI":"10.1080\/07853890.2023.2201507","volume":"55","author":"Wang","year":"2023","journal-title":"Ann Med"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"100004","DOI":"10.1016\/j.clnves.2024.100004","volume":"1","author":"Wang","year":"2025","journal-title":"Cell Investigation"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"100005","DOI":"10.1016\/j.clnves.2024.100005","volume":"1","author":"Li","year":"2025","journal-title":"Cell Investigation"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"e00181","DOI":"10.1097\/BS9.0000000000000181","volume":"6","author":"Wang","year":"2024","journal-title":"Blood Sci"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1111\/bjh.19007","volume":"203","author":"Apostolova","year":"2023","journal-title":"Br J Haematol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1884","DOI":"10.1182\/blood.2022017686","volume":"141","author":"Garcia","year":"2023","journal-title":"Blood"},{"key":"ref13","volume":"9","author":"Saberian","year":"2021","journal-title":"J Immunother Cancer"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"152804","DOI":"10.1016\/j.imbio.2024.152804","volume":"229","author":"Pan","year":"2024","journal-title":"Immunobiology"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"582955","DOI":"10.3389\/fphar.2020.582955","volume":"11","author":"Chen","year":"2020","journal-title":"Front Pharmacol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1002\/hon.3160","volume":"41","author":"N\u00fa\u00f1ez-Torr\u00f3n Stock","year":"2023","journal-title":"Hematol Oncol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"2753","DOI":"10.1182\/blood.2021013626","volume":"138","author":"Heuser","year":"2021","journal-title":"Blood"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"e152631","DOI":"10.1172\/jci.insight.152631","volume":"7","author":"Chen","year":"2022","journal-title":"JCI Insight"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1186\/s12943-024-02162-0","volume":"23","author":"Zeng","year":"2024","journal-title":"Mol Cancer"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"100002","DOI":"10.1016\/j.clnves.2024.100002","volume":"1","author":"Zheng","year":"2025","journal-title":"Cell Investigation"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"e002836","DOI":"10.1136\/jitc-2021-002836","volume":"9","author":"Wang","year":"2021","journal-title":"J Immunother Cancer"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"e775","DOI":"10.1002\/ctm2.775","volume":"12","author":"Chen","year":"2022","journal-title":"Clin Transl Med"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1158\/1538-7445.AM2023-LB245","volume":"35","author":"Chen","year":"2023","journal-title":"Chin J Cancer Res"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1186\/s13046-023-02846-3","volume":"42","author":"Palermo","year":"2023","journal-title":"J Exp Clin Cancer Res"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1265255","DOI":"10.3389\/fimmu.2023.1265255","volume":"14","author":"Ma","year":"2023","journal-title":"Front Immunol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1038\/leu.2014.173","volume":"29","author":"Walter","year":"2015","journal-title":"Leukemia"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"865","DOI":"10.3324\/haematol.2016.159343","volume":"102","author":"Buckley","year":"2017","journal-title":"Haematologica"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1200\/JCO.2015.63.3826","volume":"34","author":"Araki","year":"2016","journal-title":"J Clin Oncol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1182\/blood-2009-07-235358","volume":"115","author":"D\u00f6hner","year":"2010","journal-title":"Blood"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"2209","DOI":"10.1056\/NEJMoa1516192","volume":"374","author":"Papaemmanuil","year":"2016","journal-title":"N Engl J Med"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1182\/blood-2009-11-254441","volume":"116","author":"Grimwade","year":"2010","journal-title":"Blood"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/s40164-024-00487-6","volume":"13","author":"Zhang","year":"2024","journal-title":"Exp Hematol Oncol"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1016\/j.bbmt.2018.11.031","volume":"25","author":"Wang","year":"2019","journal-title":"Biol Blood Marrow Transplant"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"e2300042","DOI":"10.1002\/adbi.202300042","volume":"7","author":"Chen","year":"2023","journal-title":"Adv Biol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"9055","DOI":"10.1002\/cam4.5644","volume":"12","author":"Yu","year":"2023","journal-title":"Cancer Med"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"1571","DOI":"10.1038\/leu.2015.44","volume":"29","author":"Yang","year":"2015","journal-title":"Leukemia"}],"container-title":["ImmunoTargets and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/99390","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/99390","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T07:50:12Z","timestamp":1737359412000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/increased-co-expression-of-pd-l1-and-ctla-4-predicts-poor-overall-surv-peer-reviewed-fulltext-article-ITT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":36,"URL":"https:\/\/doi.org\/10.2147\/itt.s500723","relation":{},"ISSN":["2253-1556"],"issn-type":[{"value":"2253-1556","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]}}}