{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T11:30:55Z","timestamp":1776511855215,"version":"3.51.2"},"reference-count":100,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JHC"],"DOI":"10.2147\/jhc.s409526","type":"journal-article","created":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T04:10:15Z","timestamp":1694578215000},"page":"1527-1546","source":"Crossref","is-referenced-by-count":5,"title":["Al-Hijamah (Prophetic Wet Cupping Therapy) is a Novel Adjuvant Treatment for Viral Hepatitis That Excretes Viral Particles and Excess Ferritin Percutaneously, Synergizes Pharmacotherapy, Enhances Antiviral Immunity and Helps Better HCC Prevention and Treatment: A Novel Evidence-Based Combination with Prophetic Medicine Remedies"],"prefix":"10.2147","volume":"Volume 10","author":[{"given":"Salah Mohamed","family":"El Sayed","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2023,9]]},"reference":[{"key":"ref1","first-page":"504","volume":"73","author":"Gurtsevitch","year":"2008","journal-title":"Biochemistry"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"e48125","DOI":"10.1371\/journal.pone.0048125","volume":"7","author":"Traore","year":"2012","journal-title":"PLoS One"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1652","DOI":"10.3748\/wjg.14.1652","volume":"14","author":"But","year":"2008","journal-title":"World J Gastroenterol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1729","DOI":"10.1080\/14656566.2021.1921737","volume":"22","author":"Stanciu","year":"2021","journal-title":"Expert Opin Pharmacother"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"e1003653","DOI":"10.1371\/journal.pmed.1003653","volume":"18","author":"Fadnes","year":"2021","journal-title":"PLoS Med"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1743-422X-8-102","volume":"8","author":"Ali","year":"2011","journal-title":"Virol J"},{"key":"ref7","first-page":"17","volume":"83","author":"Kulikov","year":"2011","journal-title":"Ter Arkh"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"100307","DOI":"10.1016\/j.aohep.2021.100307","volume":"23","author":"Ding","year":"2021","journal-title":"Ann Hepatol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1146\/annurev.pathol.1.110304.100230","volume":"1","author":"Guidotti","year":"2006","journal-title":"Annu Rev Pathol Mech Dis"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"587628","DOI":"10.3389\/fcimb.2020.587628","volume":"10","author":"Lim","year":"2020","journal-title":"Front Cell Infect Microbiol"},{"key":"ref11","first-page":"821","author":"El Sayed","year":"2022"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"143","DOI":"10.2147\/OTT.S397593","volume":"Volume 16","author":"El Sayed","year":"2023","journal-title":"Onco Targets Ther"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1016\/j.mehy.2013.08.024","volume":"81","author":"El Sayed","year":"2013","journal-title":"Med Hypotheses"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10238-022-00897-y","author":"Xu","year":"2022","journal-title":"Clin Exp Med"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"14","DOI":"10.12691\/ajcmr-11-1-3","volume":"11","author":"El Sayed","year":"2023","journal-title":"Am J Clin Med Res"},{"key":"ref16","first-page":"1","volume":"2","author":"El Sayed","year":"2013","journal-title":"Altern Integr Med"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1002\/ar.1091730210","volume":"173","author":"Takada","year":"1972","journal-title":"Anat Rec"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"241","DOI":"10.2147\/JBM.S170523","volume":"9","author":"El-Shanshory","year":"2018","journal-title":"J Blood Med"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"e87974","DOI":"10.1371\/journal.pone.0087974","volume":"9","author":"Grammatikos","year":"2014","journal-title":"PLoS One"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1590\/S0004-28032012000100003","volume":"49","author":"Borges","year":"2012","journal-title":"Arq Gastroenterol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"2371","DOI":"10.2169\/internalmedicine.49.4088","volume":"49","author":"Hayashi","year":"2010","journal-title":"Intern Med"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1034\/j.1600-0676.2001.210501.x","volume":"21","author":"Sumida","year":"2001","journal-title":"Liver"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"e170","DOI":"10.1111\/j.1365-2893.2011.01508.x","volume":"19","author":"Sebastiani","year":"2012","journal-title":"J Viral Hepat"},{"key":"ref24","first-page":"e13136","volume":"13","author":"Vagu","year":"2013","journal-title":"Hepat Mon"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/S1665-2681(19)31385-7","volume":"12","author":"Elalfy","year":"2013","journal-title":"Ann Hepatol"},{"key":"ref26","first-page":"2130","volume":"56","author":"Abergel","year":"2006","journal-title":"Rev Prat"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.gcb.2009.07.032","volume":"34","author":"Nahon","year":"2010","journal-title":"Gastroenterol Clin Biol"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1007\/s10620-007-9945-7","volume":"53","author":"Desai","year":"2008","journal-title":"Dig Dis Sci"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1111\/j.1478-3231.2007.01449.x","volume":"27","author":"Alexander","year":"2007","journal-title":"Liver Int"},{"key":"ref30","first-page":"1467","volume":"50","author":"Carlo","year":"2003","journal-title":"Hepato-Gastroenterology"},{"key":"ref31","first-page":"125","volume":"12","author":"El-Shanshory","year":"2022","journal-title":"Am J Blood Res"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"100245","DOI":"10.1016\/j.hermed.2018.11.001","volume":"16","author":"El-Shanshory","year":"2019","journal-title":"J Herb Med"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1016\/j.mehy.2014.04.001","volume":"83","author":"El Sayed","year":"2014","journal-title":"Med Hypotheses"},{"key":"ref34","first-page":"54","volume":"8","author":"El Sayed","year":"2020","journal-title":"Am J Public Health Res"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1093\/cid\/civ419","volume":"61","author":"Harrington","year":"2015","journal-title":"Clin Infect Dis"},{"key":"ref36","first-page":"447","volume":"10","author":"El-Shanshory","year":"2020","journal-title":"Am J Blood Res"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"219","DOI":"10.2147\/JBM.S65042","volume":"5","author":"El Sayed","year":"2014","journal-title":"J Blood Med"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"207","DOI":"10.12816\/0024129","volume":"9","author":"Baghdadi","year":"2015","journal-title":"Int J Health Sci"},{"key":"ref39","first-page":"1","volume":"2","author":"Mahmoud","year":"2013","journal-title":"Altern Integ Med"},{"key":"ref40","first-page":"1","volume":"2","author":"El Sayed","year":"2013","journal-title":"Altern Integr Med"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1063423","DOI":"10.3389\/fonc.2022.1063423","volume":"12","author":"Xu","year":"2023","journal-title":"Front Oncol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"2529","DOI":"10.3748\/wjg.v19.i16.2529","volume":"19","author":"Barakat","year":"2013","journal-title":"World J Gastroenterol"},{"key":"ref43","first-page":"131","volume":"23","author":"Helal","year":"2010","journal-title":"Pak J Pharm Sci"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1746-1596-8-137","volume":"8","author":"Alimohammadi","year":"2013","journal-title":"Diagn Pathol"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/S2221-1691(13)60075-1","volume":"3","author":"Ahmad","year":"2013","journal-title":"Asian Pac J Trop Biomed"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1024\/0300-9831\/a000121","volume":"82","author":"Al-Suhaimi","year":"2012","journal-title":"Int J Vitamin Nutr Res"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1002\/cbf.1624","volume":"28","author":"Coban","year":"2010","journal-title":"Cell Biochem Funct"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"554","DOI":"10.4103\/1319-2442.235184","volume":"29","author":"Beheshti","year":"2018","journal-title":"Saudi J Kidney Dis Transpl"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/j.intimp.2012.12.020","volume":"15","author":"Bai","year":"2013","journal-title":"Int Immunopharmacol"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/S1473-0502(03)00102-2","volume":"29","author":"Straube","year":"2003","journal-title":"Transfus Apher Sci"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/S0378-8741(02)00356-2","volume":"85","author":"Al-Jishi","year":"2003","journal-title":"J Ethnopharmacol"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1093\/chrsci\/49.4.321","volume":"49","author":"Ashraf","year":"2011","journal-title":"J Chromatogr Sci"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1016\/j.freeradbiomed.2009.12.002","volume":"48","author":"Ismail","year":"2010","journal-title":"Free Radic Biol Med"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"254","DOI":"10.4161\/oxim.3.4.12714","volume":"3","author":"Sayed-Ahmed","year":"2010","journal-title":"Oxid Med Cell Longev"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"3115","DOI":"10.3923\/pjbs.2007.3115.3119","volume":"10","author":"Al-Enazi","year":"2007","journal-title":"Pak J Biol Sci"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1016\/S0192-0561(00)00036-9","volume":"22","author":"Salem","year":"2000","journal-title":"Int J Immunopharmacol"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1002\/ptr.1146","volume":"17","author":"Khan","year":"2003","journal-title":"Phytother Res"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.1002\/ptr.2487","volume":"22","author":"Al\u2010Johar","year":"2008","journal-title":"Phytother Res"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1097\/00008469-199910000-00009","volume":"8","author":"Badary","year":"1999","journal-title":"Eur J Cancer Prev"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.rvsc.2004.03.002","volume":"77","author":"Fararh","year":"2004","journal-title":"Res Vet Sci"},{"key":"ref61","first-page":"105","volume":"9","author":"El Daly","year":"1996","journal-title":"J Islamic Acad Sci"},{"key":"ref62","first-page":"362","volume":"25","author":"Badary","year":"2001","journal-title":"Cancer Detect Prev"},{"key":"ref63","first-page":"282","volume":"19","author":"Nili-Ahmadabadi","year":"2011","journal-title":"Daru"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/j.jep.2009.11.001","volume":"127","author":"Khader","year":"2010","journal-title":"J Ethnopharmacol"},{"key":"ref65","first-page":"569","volume":"17","author":"Hamed","year":"2013","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"ref66","doi-asserted-by":"publisher","first-page":"678","DOI":"10.4103\/0253-7613.103239","volume":"44","author":"Hassan","year":"2012","journal-title":"Indian J Pharmacol"},{"key":"ref67","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/s12199-012-0292-8","volume":"18","author":"Abdel-Hamid","year":"2013","journal-title":"Environ Health Prev Med"},{"key":"ref68","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1016\/j.jep.2013.05.004","volume":"148","author":"Sayeed","year":"2013","journal-title":"J Ethnopharmacol"},{"key":"ref69","first-page":"25","volume":"20","author":"Al-Ali","year":"2008","journal-title":"J Ayub Med Coll Abbottabad"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"97","DOI":"10.5681\/apb.2013.016","volume":"3","author":"Dollah","year":"2013","journal-title":"Adv Pharm Bull"},{"key":"ref71","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.amjsurg.2007.04.011","volume":"195","author":"K\u0131l\u0131coglu","year":"2008","journal-title":"Am J Surg"},{"key":"ref72","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1046\/j.1365-2672.2003.02050.x","volume":"95","author":"Miorin","year":"2003","journal-title":"J Appl Microbiol"},{"key":"ref73","doi-asserted-by":"publisher","first-page":"957932","DOI":"10.3389\/fnut.2022.957932","volume":"9","author":"Schell","year":"2022","journal-title":"Front Nutr"},{"key":"ref74","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1472-6882-6-6","volume":"6","author":"Ezz El-Arab","year":"2006","journal-title":"BMC Complement Altern Med"},{"key":"ref75","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1089\/jmf.2008.0203","volume":"12","author":"\u00c7avu\u015fo\u011flu","year":"2009","journal-title":"J Med Food"},{"key":"ref76","doi-asserted-by":"publisher","first-page":"e54515","DOI":"10.1371\/journal.pone.0054515","volume":"8","author":"Mussulini","year":"2013","journal-title":"PLoS One"},{"key":"ref77","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.taap.2010.12.004","volume":"251","author":"Khan","year":"2011","journal-title":"Toxicol Appl Pharmacol"},{"key":"ref78","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1159\/000136479","volume":"41","author":"Kismet","year":"2008","journal-title":"Eur Surg Res"},{"key":"ref79","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/0166-3542(94)00083-K","volume":"27","author":"Chen","year":"1995","journal-title":"Antiviral Res"},{"key":"ref80","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/j.jpba.2011.11.016","volume":"61","author":"Nugroho","year":"2012","journal-title":"J Pharm Biomed Anal"},{"key":"ref81","doi-asserted-by":"publisher","first-page":"S229","DOI":"10.1002\/ptr.3089","volume":"24","author":"Yaeesh","year":"2010","journal-title":"Phytother Res"},{"key":"ref82","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1016\/j.jep.2006.12.033","volume":"110","author":"Pandey","year":"2007","journal-title":"J Ethnopharmacol"},{"key":"ref83","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1124\/jpet.108.148395","volume":"329","author":"Hsu","year":"2009","journal-title":"J Pharmacol Exp Ther"},{"key":"ref84","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.ejphar.2004.03.027","volume":"492","author":"Cho","year":"2004","journal-title":"Eur J Pharmacol"},{"key":"ref85","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12906-015-0836-8","volume":"15","author":"Selim","year":"2015","journal-title":"BMC Complement Altern Med"},{"key":"ref86","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.3892\/etm.2017.4159","volume":"13","author":"El-Fakharany","year":"2017","journal-title":"Exp Ther Med"},{"key":"ref87","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12906-017-1926-6","volume":"17","author":"Khan","year":"2017","journal-title":"BMC Complement Altern Med"},{"key":"ref88","doi-asserted-by":"publisher","first-page":"2601","DOI":"10.2147\/DDDT.S344247","author":"Hassan","year":"2022","journal-title":"Drug Des Devel Ther"},{"key":"ref89","first-page":"26","volume":"2","author":"Al-Ghasham","year":"2008","journal-title":"Int J Health Sci"},{"key":"ref90","first-page":"2161","volume":"3","author":"Ragab","year":"2013","journal-title":"J Environ Anal Toxicol"},{"key":"ref91","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/j.etp.2010.03.002","volume":"63","author":"Saafi","year":"2011","journal-title":"Exp Toxicol Pathol"},{"key":"ref92","doi-asserted-by":"publisher","first-page":"2351","DOI":"10.1002\/jsfa.6154","volume":"93","author":"Tang","year":"2013","journal-title":"J Sci Food Agric"},{"key":"ref93","doi-asserted-by":"publisher","first-page":"46","DOI":"10.12691\/ajmbr-2-2-3","volume":"2","author":"El Sayed","year":"2014","journal-title":"Am J Med Biol Res"},{"key":"ref94","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1111\/jvh.12795","volume":"25","author":"Camus","year":"2018","journal-title":"J Viral Hepat"},{"key":"ref95","first-page":"397","volume":"10","author":"El Sayed","year":"2020","journal-title":"Am J Blood Res"},{"key":"ref96","first-page":"54","volume":"8","author":"El Sayed","year":"2020","journal-title":"Am J Public Health Res"},{"key":"ref97","first-page":"266","volume":"10","author":"El Sayed","year":"2020","journal-title":"Am J Blood Res"},{"key":"ref98","volume-title":"StatPearls [Internet]","year":"2022"},{"key":"ref99","doi-asserted-by":"publisher","first-page":"1736","DOI":"10.3390\/jcm8101736","volume":"8","author":"Lee","year":"2019","journal-title":"J Clin Med"},{"key":"ref100","first-page":"984","volume":"26","author":"Zhang","year":"2006","journal-title":"Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi"}],"container-title":["Journal of Hepatocellular Carcinoma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=92752","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=92752","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T04:10:38Z","timestamp":1694578238000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/al-hijamah-prophetic-wet-cupping-therapy-is-a-novel-adjuvant-treatment-peer-reviewed-fulltext-article-JHC"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":100,"URL":"https:\/\/doi.org\/10.2147\/jhc.s409526","relation":{},"ISSN":["2253-5969"],"issn-type":[{"value":"2253-5969","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9]]}}}