{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T12:31:15Z","timestamp":1774355475574,"version":"3.50.1"},"reference-count":32,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JHC"],"DOI":"10.2147\/jhc.s600757","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T11:40:13Z","timestamp":1774352413000},"page":"1-12","source":"Crossref","is-referenced-by-count":0,"title":["Development and Validation of the TCAP Nomogram for Predicting Hepatotoxicity Risk in Hepatocellular Carcinoma Patients Receiving TACE Combined with Systemic Therapy"],"prefix":"10.2147","volume":"Volume 13","author":[{"given":"Shuangshuang","family":"Ma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Congcong","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinlong","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinpeng","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2026,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.jncc.2024.01.006","volume":"4","author":"Han","year":"2024","journal-title":"J Natl Cancer Cent"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.cld.2022.08.004","volume":"27","author":"Ganesan","year":"2023","journal-title":"Clin Liver Dis"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1002\/hep.28453","volume":"64","author":"Lencioni","year":"2016","journal-title":"Hepatology"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"1894","DOI":"10.1056\/NEJMoa1915745","volume":"382","author":"Finn","year":"2020","journal-title":"N Engl J Med"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"EVIDoa2100070","DOI":"10.1056\/EVIDoa2100070","volume":"1","author":"Abou-Alfa","year":"2022","journal-title":"NEJM Evid"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1379622","DOI":"10.3389\/fimmu.2024.1379622","volume":"15","author":"Berber","year":"2024","journal-title":"Front Immunol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1016\/j.jhep.2023.10.040","volume":"80","author":"Celsa","year":"2024","journal-title":"J Hepatol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1492","DOI":"10.1136\/gutjnl-2019-318934","volume":"69","author":"Kudo","year":"2020","journal-title":"Gut"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1016\/S1470-2045(18)30937-9","volume":"20","author":"Zhu","year":"2019","journal-title":"Lancet Oncol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1016\/S0140-6736(18)30207-1","volume":"391","author":"Kudo","year":"2018","journal-title":"Lancet"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2025.102896","author":"Cabibbo","year":"2025","journal-title":"Cancer Treat Rev"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1097\/HEP.0000000000000205","volume":"77","author":"Cabibbo","year":"2023","journal-title":"Hepatology"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1016\/j.jhep.2021.07.004","volume":"75","author":"Bruix","year":"2021","journal-title":"J Hepatol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"e2","DOI":"10.1056\/NEJMc1906565","volume":"381","author":"Duran","year":"2019","journal-title":"N Engl J Med"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1200\/JCO.2014.57.9151","volume":"33","author":"Johnson","year":"2015","journal-title":"J Clin Oncol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1111\/jgh.13250","volume":"31","author":"Hiraoka","year":"2016","journal-title":"J Gastroenterol Hepatol"},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"National HCOT. National guidelines for diagnosis and treatment of cervical cancer 2022 in China (English version). Chin J Cancer Res. 2022;34(3):256\u2013269. doi:10.21147\/j.issn.1000-9604.2022.03.06","DOI":"10.21147\/j.issn.1000-9604.2022.03.06"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"2674","DOI":"10.3760\/cma.j.cn112137-20230630-01114","volume":"103","author":"Hepatology","year":"2023","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.ad.2019.05.009","volume":"112","author":"Freites-Martinez","year":"2021","journal-title":"Actas Dermosifiliogr"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"1071860","DOI":"10.3389\/fonc.2022.1071860","volume":"12","author":"Li","year":"2022","journal-title":"Front Oncol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/j.jhep.2019.09.025","volume":"72","author":"Cheng","year":"2020","journal-title":"J Hepatol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/j.jhep.2019.10.021","volume":"72","author":"Sangro","year":"2020","journal-title":"J Hepatol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"1766","DOI":"10.1111\/jgh.13339","volume":"31","author":"Chan","year":"2016","journal-title":"J Gastroenterol Hepatol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1159\/000479984","volume":"6","author":"Hiraoka","year":"2017","journal-title":"Liver Cancer"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000521374","volume":"11","author":"Kudo","year":"2022","journal-title":"Liver Cancer"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1159\/000480256","volume":"35","author":"Hiraoka","year":"2017","journal-title":"Dig Dis"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1269","DOI":"10.1152\/physrev.00027.2008","volume":"89","author":"Vollmar","year":"2009","journal-title":"Physiol Rev"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1230","DOI":"10.1038\/s12276-020-0483-0","volume":"52","author":"So","year":"2020","journal-title":"Exp Mol Med"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"6398","DOI":"10.3748\/wjg.v19.i38.6398","volume":"19","author":"Sticova","year":"2013","journal-title":"World J Gastroenterol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1177\/13.8.740","volume":"13","author":"Barnhart","year":"1965","journal-title":"J Histochem Cytochem"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1002\/hep.29086","volume":"67","author":"Heimbach","year":"2018","journal-title":"Hepatology"}],"container-title":["Journal of Hepatocellular Carcinoma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/113405","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/113405","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T11:40:16Z","timestamp":1774352416000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/development-and-validation-of-the-tcap-nomogram-for-predicting-hepatot-peer-reviewed-fulltext-article-JHC"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":32,"URL":"https:\/\/doi.org\/10.2147\/jhc.s600757","relation":{},"ISSN":["2253-5969"],"issn-type":[{"value":"2253-5969","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]}}}