{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:23:05Z","timestamp":1790126585630,"version":"4.0.1"},"reference-count":45,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JIR"],"DOI":"10.2147\/jir.s325528","type":"journal-article","created":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T16:22:38Z","timestamp":1628612558000},"page":"3863-3877","source":"Crossref","is-referenced-by-count":14,"title":["Neuroinflammation and Microglial Activation at Rostral Ventrolateral Medulla Underpin Cadmium-Induced Cardiovascular Dysregulation in Rats"],"prefix":"10.2147","volume":"Volume 14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9548-9851","authenticated-orcid":true,"given":"Ching-Yi","family":"Tsai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline CC","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiung-Ju","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuang-Yu","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu-Mi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2021,8]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"World Health Organization. Environmental Health Criteria 134, Cadmium. 1st ed. Geneva, Switzerland: World Health Organization; 2012.","DOI":"10.7591\/cornell\/9780801450655.003.0001"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"191","DOI":"10.2131\/jts.37.191","volume":"37","author":"Miura","year":"2012","journal-title":"J Toxicol Sci"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1177\/096032719601500507","volume":"15","author":"Shukla","year":"1996","journal-title":"Hum Exp Toxicol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"898034","DOI":"10.1155\/2013\/898034","volume":"2013","author":"Wang","year":"2013","journal-title":"Oxid Med Cell Longev"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1093\/toxsci\/kfu208","volume":"143","author":"Ashok","year":"2015","journal-title":"Toxicol Sci"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1035","DOI":"10.1016\/j.freeradbiomed.2008.07.011","volume":"45","author":"Chen","year":"2008","journal-title":"Free Radic Biol Med"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1016\/j.neuropharm.2016.01.030","volume":"105","author":"Xu","year":"2016","journal-title":"Neuropharmacology"},{"key":"ref8","first-page":"2734","volume":"61","author":"Favorito","year":"2017","journal-title":"Eur J Histochem"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1093\/toxsci\/kfm106","volume":"98","author":"Yang","year":"2007","journal-title":"Toxicol Sci"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0306-4522(90)90229-W","volume":"39","author":"Lawson","year":"1990","journal-title":"Neuroscience"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1007\/s11011-014-9531-6","volume":"30","author":"Kawabori","year":"2015","journal-title":"Metab Brain Dis"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"33","DOI":"10.5607\/en.2017.26.1.33","volume":"26","author":"Choi","year":"2017","journal-title":"Exp Neurobiol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1002\/glia.23091","volume":"65","author":"Menzel","year":"2017","journal-title":"Glia"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"7425","DOI":"10.3390\/ijms21197425","volume":"21","author":"Jung","year":"2020","journal-title":"Int J Mol Sci"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"17023","DOI":"10.1038\/sigtrans.2017.23","volume":"2","author":"Liu","year":"2017","journal-title":"Signal Transduct Target Ther"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"772","DOI":"10.3389\/fphys.2019.00772","volume":"10","author":"Chen","year":"2019","journal-title":"Front Physiol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1038\/nrn1902","volume":"7","author":"Guyenet","year":"2006","journal-title":"Nat Rev Neurosci"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1161\/HYPERTENSIONAHA.108.116905","volume":"53","author":"Chan","year":"2009","journal-title":"Hypertension"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1016\/j.freeradbiomed.2005.04.012","volume":"39","author":"Chan","year":"2005","journal-title":"Free Radic Biol Med"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"104791","DOI":"10.1016\/j.neuint.2020.104791","volume":"139","author":"Tsai","year":"2020","journal-title":"Neurochem Int"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1186\/s12974-019-1623-0","volume":"16","author":"Fu","year":"2019","journal-title":"J Neuroinflammation"},{"key":"ref22","first-page":"1568","volume":"275","author":"Yang","year":"1995","journal-title":"J Pharmacol Exp Ther"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"H485","DOI":"10.1152\/ajpcell.1997.272.2.C485","volume":"272","author":"Kuo","year":"1997","journal-title":"Am J Physiol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"H555","DOI":"10.1152\/ajpheart.00246.2016","volume":"311","author":"Poon","year":"2016","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"40111","DOI":"10.1038\/srep40111","volume":"7","author":"Tsai","year":"2017","journal-title":"Sci Rep"},{"key":"ref26","first-page":"57648","volume":"136","author":"Young","year":"2018","journal-title":"J Vis Exp"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/0166-2236(96)10049-7","volume":"19","author":"Kreutzberg","year":"1996","journal-title":"Trends Neurosci"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"101438","DOI":"10.1016\/j.tice.2020.101438","volume":"68","author":"Tu","year":"2021","journal-title":"Tissue Cell"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.neuro.2017.03.001","volume":"60","author":"Phuagkhaopong","year":"2017","journal-title":"Neurotoxicology"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"4585","DOI":"10.1074\/jbc.M603394200","volume":"282","author":"Chan","year":"2007","journal-title":"J Biol Chem"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"e7744","DOI":"10.1371\/journal.pone.0007744","volume":"4","author":"Chang","year":"2009","journal-title":"PLoS One"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"36027","DOI":"10.1074\/jbc.M304854200","volume":"278","author":"Chen","year":"2003","journal-title":"J Biol Chem"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"1434","DOI":"10.1016\/j.freeradbiomed.2004.03.010","volume":"36","author":"Wang","year":"2004","journal-title":"Free Radic Biol Med"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"1699","DOI":"10.1007\/s00018-015-2094-9","volume":"73","author":"Messner","year":"2016","journal-title":"Cell Mol Life Sci"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"3560","DOI":"10.1161\/01.CIR.0000143082.63063.33","volume":"110","author":"Chan","year":"2004","journal-title":"Circulation"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.yexmp.2015.02.003","volume":"98","author":"Yang","year":"2015","journal-title":"Exp Mol Pathol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1113\/EP086780","volume":"103","author":"Silva","year":"2018","journal-title":"Exp Physiol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"282","DOI":"10.3389\/fnagi.2017.00282","volume":"9","author":"Zhang","year":"2017","journal-title":"Front Aging Neurosci"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1038\/40901","volume":"388","author":"Deveraux","year":"1997","journal-title":"Nature"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"105715","DOI":"10.1016\/j.biocel.2020.105715","volume":"121","author":"Zhao","year":"2020","journal-title":"Int J Biochem Cell Biol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"23453","DOI":"10.1007\/s11356-019-05675-0","volume":"26","author":"Tang","year":"2019","journal-title":"Environ Sci Pollut Res Int"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"1222","DOI":"10.3390\/nu12051222","volume":"12","author":"Benvenga","year":"2020","journal-title":"Nutrients"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"152855","DOI":"10.1016\/j.tox.2021.152855","volume":"459","author":"Xue","year":"2021","journal-title":"Toxicology"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"9162946","DOI":"10.1155\/2018\/9162946","volume":"2018","author":"Micali","year":"2018","journal-title":"Oxid Med Cell Longev"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1016\/j.bbrc.2004.05.218","volume":"320","author":"Jeong","year":"2004","journal-title":"Biochem Biophys Res Commun"}],"container-title":["Journal of Inflammation Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=72511","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=72511","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T16:23:00Z","timestamp":1628612580000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/neuroinflammation-and-microglial-activation-at-rostral-ventrolateral-m-peer-reviewed-fulltext-article-JIR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":45,"URL":"https:\/\/doi.org\/10.2147\/jir.s325528","relation":{},"ISSN":["1178-7031"],"issn-type":[{"value":"1178-7031","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8]]}}}