{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T07:17:37Z","timestamp":1773127057025,"version":"3.50.1"},"reference-count":41,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JIR"],"DOI":"10.2147\/jir.s338598","type":"journal-article","created":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T17:50:53Z","timestamp":1643737853000},"page":"635-648","source":"Crossref","is-referenced-by-count":11,"title":["IL-17 is a Potential Therapeutic Target in a Rodent Model of Otitis Media with Effusion"],"prefix":"10.2147","volume":"Volume 15","author":[{"given":"Nanfeng","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tingting","family":"Qian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2142-4307","authenticated-orcid":true,"given":"Shan","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3754-3434","authenticated-orcid":true,"given":"Zhixian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danling","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peifan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingfang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huawei","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianming","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2022,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"16063","DOI":"10.1038\/nrdp.2016.63","volume":"2","author":"Schilder","year":"2016","journal-title":"Nat Rev Dis Primers"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"e36226","DOI":"10.1371\/journal.pone.0036226","volume":"7","author":"Monasta","year":"2012","journal-title":"PLoS One"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1016\/S0140-6736(18)31862-2","volume":"392","author":"Pichichero","year":"2018","journal-title":"Lancet"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1177\/0194599815623467","volume":"154","author":"Rosenfeld","year":"2016","journal-title":"Otolaryngol Head Neck Surg"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1016\/S0140-6736(04)15495-0","volume":"363","author":"Rovers","year":"2004","journal-title":"Lancet"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1542\/peds.2007-3349","volume":"123","author":"Thompson","year":"2009","journal-title":"Pediatrics"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1086\/528685","volume":"46","author":"Chonmaitree","year":"2008","journal-title":"Clin Infect Dis"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1111\/j.1365-2273.2004.00833.x","volume":"29","author":"Waldron","year":"2004","journal-title":"Clin Otolaryngol Allied Sci"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/s0165-5876(97)00113-4","volume":"42","author":"Cohen","year":"1997","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1080\/14992020802331230","volume":"47","author":"Casselbrant","year":"2008","journal-title":"Int J Audiol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1136\/adc.85.2.91","volume":"85","author":"Bennett","year":"2001","journal-title":"Arch Dis Child"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1016\/j.ijporl.2014.12.030","volume":"79","author":"Elicora","year":"2015","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/s0165-5876(99)00037-3","volume":"48","author":"Engel","year":"1999","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1403","DOI":"10.1016\/j.ijporl.2013.07.015","volume":"77","author":"Kuo","year":"2013","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.ijid.2014.10.015","volume":"29","author":"Mittal","year":"2014","journal-title":"Int J Infect Dis"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1111\/j.1398-9995.2006.00971.x","volume":"61","author":"Chantzi","year":"2006","journal-title":"Allergy"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1416","DOI":"10.1016\/j.ijporl.2012.06.013","volume":"76","author":"Daniel","year":"2012","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"4003","DOI":"10.1007\/s00405-016-4094-2","volume":"273","author":"Tawfik","year":"2016","journal-title":"Eur Arch Oto-Rhino-L"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.1099\/jmm.0.001227","volume":"69","author":"Christensen","year":"2020","journal-title":"J Med Microbiol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1007\/s11882-010-0158-3","volume":"11","author":"Leichtle","year":"2011","journal-title":"Curr Allergy Asthma Rep"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"e96","DOI":"10.1097\/inf.0b013e3181fcd9e8","volume":"29","author":"MacIntyre","year":"2010","journal-title":"Pediatr Infect Dis J"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1007\/s11882-012-0308-x","volume":"12","author":"MacIntyre","year":"2012","journal-title":"Curr Allergy Asthma Rep"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1016\/j.jgg.2014.10.003","volume":"41","author":"Mittal","year":"2014","journal-title":"J Genet Genomics"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1097\/01.mao.0000224087.93096.4d","volume":"27","author":"Kariya","year":"2006","journal-title":"Otol Neurotol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1080\/00016480510035449","volume":"125","author":"Smirnova","year":"2005","journal-title":"Acta Otolaryngol"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00147-20","volume":"88","author":"Enoksson","year":"2020","journal-title":"Infect Immun"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1007\/s00405-015-3683-9","volume":"273","author":"Zielnik-Jurkiewicz","year":"2016","journal-title":"Eur Arch Oto-Rhino-L"},{"key":"ref28","first-page":"520","volume":"16","author":"Yeghaneh Moghaddam","year":"2017","journal-title":"Iran J Allergy Asthma Immunol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1097\/INF.0000000000001493","volume":"36","author":"Krueger","year":"2017","journal-title":"Pediatr Infect Dis J"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"222","DOI":"10.4049\/jimmunol.1003606","volume":"187","author":"Kang","year":"2011","journal-title":"J Immunol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1177\/00034894760850S218","volume":"85","author":"Bernstein","year":"1976","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1067\/mhn.2001.119140","volume":"125","author":"Hardy","year":"2001","journal-title":"Otolaryngol Head Neck Surg"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1016\/S0140-6736(18)31490-9","volume":"392","author":"Francis","year":"2018","journal-title":"Lancet"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1038\/s41577-018-0044-0","volume":"18","author":"Borst","year":"2018","journal-title":"Nat Rev Immunol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1038\/nri3707","volume":"14","author":"Gaffen","year":"2014","journal-title":"Nat Rev Immunol"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1111\/j.1365-2133.2008.08902.x","volume":"160","author":"Johansen","year":"2009","journal-title":"Br J Dermatol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"7128","DOI":"10.4049\/jimmunol.179.10.7128","volume":"179","author":"Yamaguchi","year":"2007","journal-title":"J Immunol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1564","DOI":"10.1016\/S0140-6736(21)00440-2","volume":"397","author":"Papp","year":"2021","journal-title":"Lancet"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"ii43","DOI":"10.1093\/rheumatology\/kew346","volume":"55","author":"Nirula","year":"2016","journal-title":"Rheumatology"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"668207","DOI":"10.3389\/fimmu.2021.668207","volume":"12","author":"Christopoulos","year":"2021","journal-title":"Front Immunol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1038\/cmi.2015.105","volume":"13","author":"Song","year":"2016","journal-title":"Cell Mol Immunol"}],"container-title":["Journal of Inflammation Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=77988","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=77988","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T17:50:57Z","timestamp":1643737857000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/il-17-is-a-potential-therapeutic-target-in-a-rodent-model-of-otitis-me-peer-reviewed-fulltext-article-JIR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":41,"URL":"https:\/\/doi.org\/10.2147\/jir.s338598","relation":{},"ISSN":["1178-7031"],"issn-type":[{"value":"1178-7031","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2]]}}}