{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T23:00:04Z","timestamp":1783465204501,"version":"3.55.0"},"reference-count":88,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JIR"],"DOI":"10.2147\/jir.s388216","type":"journal-article","created":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T23:25:05Z","timestamp":1672961105000},"page":"57-67","source":"Crossref","is-referenced-by-count":33,"title":["Pathogenesis and Therapy of Coagulation Disorders in Severe Acute Pancreatitis"],"prefix":"10.2147","volume":"Volume 16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4867-9860","authenticated-orcid":true,"given":"Menglu","family":"Gui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erzhen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongping","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enqiang","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,1]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1038\/s41575-018-0087-5","volume":"16","author":"Petrov","year":"2019","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1053\/j.gastro.2021.09.043","volume":"162","author":"Iannuzzi","year":"2022","journal-title":"Gastroenterology"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"197","DOI":"10.3892\/etm.2022.11120","volume":"23","author":"Padureanu","year":"2022","journal-title":"Exp Ther Med"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1002\/bjs.5316","volume":"93","author":"Cuthbertson","year":"2006","journal-title":"Br J Surg"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1023\/A:1013284008219","volume":"47","author":"Foitzik","year":"2002","journal-title":"Dig Dis Sci"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"e15648","DOI":"10.1097\/MD.0000000000015648","volume":"98","author":"Liu","year":"2019","journal-title":"Medicine"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1177\/0300060516677929","volume":"45","author":"Yang","year":"2017","journal-title":"J Int Med Res"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"4054","DOI":"10.3748\/wjg.v24.i35.4054","volume":"24","author":"Ding","year":"2018","journal-title":"World J Gastroenterol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/S1015-9584(09)60017-8","volume":"32","author":"Lu","year":"2009","journal-title":"Asian J Surg"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"320","DOI":"10.5152\/TJAR.2019.42709","volume":"47","author":"Yano","year":"2019","journal-title":"Turk J Anaesthesiol Reanim"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1016\/j.pan.2015.08.002","volume":"15","author":"Eguchi","year":"2015","journal-title":"Pancreatology"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.pan.2018.02.009","volume":"18","author":"Hollemans","year":"2018","journal-title":"Pancreatology"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1007\/s10620-012-2034-6","volume":"57","author":"Zhu","year":"2012","journal-title":"Dig Dis Sci"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.26402\/jpp.2020.3.13","volume":"71","author":"Maduzia","year":"2020","journal-title":"J Physiol Pharmacol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"753","DOI":"10.3390\/ijms18040753","volume":"18","author":"Dumnicka","year":"2017","journal-title":"Int J Mol Sci"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1979","DOI":"10.1053\/j.gastro.2019.01.268","volume":"156","author":"Saluja","year":"2019","journal-title":"Gastroenterology"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1038\/s41575-019-0158-2","volume":"16","author":"Lee","year":"2019","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.jim.2009.08.007","volume":"350","author":"Macey","year":"2009","journal-title":"J Immunol Methods"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"2775","DOI":"10.2174\/092986706778522011","volume":"13","author":"Pereda","year":"2006","journal-title":"Curr Med Chem"},{"key":"ref20","first-page":"967","volume":"85","author":"Grignani","year":"2000","journal-title":"Haematologica"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1023\/A:1013952114485","volume":"67","author":"Dugina","year":"2002","journal-title":"Biochemistry"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1055\/s-0030-1254052","volume":"36","author":"Lisman","year":"2010","journal-title":"Semin Thromb Hemost"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1038\/s41422-020-0275-z","volume":"30","author":"Schmaier","year":"2020","journal-title":"Cell Res"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1097\/MPA.0b013e3181a66860","volume":"38","author":"Radenkovic","year":"2009","journal-title":"Pancreas"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"6128","DOI":"10.3748\/wjg.v16.i48.6128","volume":"16","author":"Andersson","year":"2010","journal-title":"World J Gastroenterol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"906","DOI":"10.1182\/blood-2018-11-882993","volume":"133","author":"Jackson","year":"2019","journal-title":"Blood"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1007\/s00134-001-1194-1","volume":"28","author":"Eibl","year":"2002","journal-title":"Intensive Care Med"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.cca.2019.01.024","volume":"491","author":"Yuan","year":"2019","journal-title":"Clin Chim Acta"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1161\/ATVBAHA.115.305996","volume":"36","author":"Mast","year":"2016","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.ccc.2019.12.002","volume":"36","author":"Sungurlu","year":"2020","journal-title":"Crit Care Clin"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1159\/000333481","volume":"11","author":"Lindstrom","year":"2011","journal-title":"Pancreatology"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.1007\/s00535-009-0096-9","volume":"44","author":"Yasuda","year":"2009","journal-title":"J Gastroenterol"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"1941","DOI":"10.1111\/jth.14246","volume":"16","author":"Zelaya","year":"2018","journal-title":"J Thromb Haemost"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1097\/MOH.0000000000000416","volume":"25","author":"Pendurthi","year":"2018","journal-title":"Curr Opin Hematol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.5858\/arpa.2017-0403-RS","volume":"143","author":"Dinarvand","year":"2019","journal-title":"Arch Pathol Lab Med"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"R16","DOI":"10.1186\/cc3966","volume":"10","author":"Lindstrom","year":"2006","journal-title":"Crit Care"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.pan.2016.12.005","volume":"17","author":"Chen","year":"2017","journal-title":"Pancreatology"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1055\/s-2006-939554","volume":"32","author":"Esmon","year":"2006","journal-title":"Semin Thromb Hemost"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"980","DOI":"10.1111\/j.1538-7836.2007.02480.x","volume":"5","author":"Villegas-Mendez","year":"2007","journal-title":"J Thromb Haemost"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"2521","DOI":"10.1182\/blood-2009-02-205914","volume":"114","author":"Song","year":"2009","journal-title":"Blood"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"1497","DOI":"10.1182\/blood-2014-10-604553","volume":"125","author":"Dargaud","year":"2015","journal-title":"Blood"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3109\/00365513.2015.1084041","volume":"76","author":"Kyhala","year":"2016","journal-title":"Scand J Clin Lab Invest"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"R184","DOI":"10.1186\/cc3485","volume":"9","author":"Yamanel","year":"2005","journal-title":"Crit Care"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"8","DOI":"10.3390\/ijms22084283","volume":"22","author":"Schlommer","year":"2021","journal-title":"Int J Mol Sci"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1159\/000485613","volume":"36","author":"Fidan","year":"2018","journal-title":"Dig Dis"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1007\/s11684-017-0553-4","volume":"12","author":"Wang","year":"2018","journal-title":"Front Med"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1186\/s40560-014-0051-6","volume":"2","author":"Iba","year":"2014","journal-title":"J Intensive Care"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"363","DOI":"10.5009\/gnl.2013.7.3.363","volume":"7","author":"Nakahara","year":"2013","journal-title":"Gut Liver"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1111\/j.1538-7836.2005.01697.x","volume":"4","author":"Kienast","year":"2006","journal-title":"J Thromb Haemost"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/s40560-015-0075-6","volume":"3","author":"Madoiwa","year":"2015","journal-title":"J Intensive Care"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"1695","DOI":"10.2174\/1389450120666190715102510","volume":"20","author":"Urano","year":"2019","journal-title":"Curr Drug Targets"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1097\/mpa.0b013e3180335c64","volume":"34","author":"Nakajima","year":"2007","journal-title":"Pancreas"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1002\/cphy.c160004","volume":"6","author":"Kaji","year":"2016","journal-title":"Compr Physiol"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.blre.2014.09.003","volume":"29","author":"Chapin","year":"2015","journal-title":"Blood Rev"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"2013","DOI":"10.1160\/TH17-03-0219","volume":"117","author":"Fender","year":"2017","journal-title":"Thromb Haemost"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"23","DOI":"10.3390\/molecules24234414","volume":"24","author":"Lordan","year":"2019","journal-title":"Molecules"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"11","DOI":"10.3390\/biomedicines9111707","volume":"9","author":"Zinellu","year":"2021","journal-title":"Biomedicines"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"6361","DOI":"10.3748\/wjg.v26.i41.6361","volume":"26","author":"Zhang","year":"2020","journal-title":"World J Gastroenterol"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1093\/cvr\/cvv048","volume":"107","author":"Rossaint","year":"2015","journal-title":"Cardiovasc Res"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1161\/ATVBAHA.109.200964","volume":"31","author":"Zwicker","year":"2011","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1097\/MPA.0000000000001009","volume":"47","author":"Tsaroucha","year":"2018","journal-title":"Pancreas"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1182\/bloodadvances.2018026294","volume":"3","author":"Setiadi","year":"2019","journal-title":"Blood Adv"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1002\/bjs.7775","volume":"99","author":"Hartman","year":"2012","journal-title":"Br J Surg"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1161\/ATVBAHA.115.305378","volume":"35","author":"Jin","year":"2015","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1159\/000212098","volume":"9","author":"Hackert","year":"2009","journal-title":"Pancreatology"},{"key":"ref66","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1189\/jlb.3A0415-161R","volume":"99","author":"Carestia","year":"2016","journal-title":"J Leukoc Biol"},{"key":"ref67","doi-asserted-by":"publisher","first-page":"2133","DOI":"10.1182\/blood-2012-06-437772","volume":"120","author":"Darbousset","year":"2012","journal-title":"Blood"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"3","DOI":"10.3390\/ijms23031411","volume":"23","author":"Carminita","year":"2022","journal-title":"Int J Mol Sci"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1038\/s41420-018-0073-2","volume":"4","author":"Nakazawa","year":"2018","journal-title":"Cell Death Discov"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"85","DOI":"10.3389\/fcvm.2019.00085","volume":"6","author":"Zucoloto","year":"2019","journal-title":"Front Cardiovasc Med"},{"key":"ref71","doi-asserted-by":"publisher","first-page":"1920","DOI":"10.1053\/j.gastro.2015.08.026","volume":"149","author":"Merza","year":"2015","journal-title":"Gastroenterology"},{"key":"ref72","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.129270","author":"Madhi","year":"2019","journal-title":"JCI Insight"},{"key":"ref73","doi-asserted-by":"publisher","first-page":"1756284820974913","DOI":"10.1177\/1756284820974913","volume":"13","author":"Hu","year":"2020","journal-title":"Therap Adv Gastroenterol"},{"key":"ref74","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.tmrv.2019.08.004","volume":"33","author":"Dzik","year":"2019","journal-title":"Transfus Med Rev"},{"key":"ref75","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1097\/MBC.0000000000000720","volume":"29","author":"Conway","year":"2018","journal-title":"Blood Coagul Fibrinolysis"},{"key":"ref76","doi-asserted-by":"publisher","first-page":"e23205","DOI":"10.1002\/jcla.23205","volume":"34","author":"Zhang","year":"2020","journal-title":"J Clin Lab Anal"},{"key":"ref77","doi-asserted-by":"publisher","first-page":"15","DOI":"10.3389\/fimmu.2017.00015","volume":"8","author":"Bettac","year":"2017","journal-title":"Front Immunol"},{"key":"ref78","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1084\/jem.20041497","volume":"201","author":"Del Conde","year":"2005","journal-title":"J Exp Med"},{"key":"ref79","first-page":"1","volume":"2021","author":"Linders","year":"2021","journal-title":"Eur Surg Res"},{"key":"ref80","doi-asserted-by":"publisher","first-page":"11850","DOI":"10.1002\/jcp.27874","volume":"234","author":"Madhi","year":"2019","journal-title":"J Cell Physiol"},{"key":"ref81","doi-asserted-by":"publisher","first-page":"28","DOI":"10.3389\/fimmu.2019.00028","volume":"10","author":"Murthy","year":"2019","journal-title":"Front Immunol"},{"key":"ref82","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1016\/j.cgh.2013.09.068","volume":"12","author":"Easler","year":"2014","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref83","doi-asserted-by":"publisher","first-page":"100615","DOI":"10.1016\/j.blre.2019.100615","volume":"39","author":"Lin","year":"2020","journal-title":"Blood Rev"},{"key":"ref84","doi-asserted-by":"publisher","first-page":"11","DOI":"10.3390\/molecules25112493","volume":"25","author":"Maduzia","year":"2020","journal-title":"Molecules"},{"key":"ref85","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1097\/SHK.0000000000000946","volume":"49","author":"Kong","year":"2018","journal-title":"Shock"},{"key":"ref86","doi-asserted-by":"publisher","first-page":"81","DOI":"10.5152\/tjg.2018.18583","volume":"30","author":"Tozlu","year":"2019","journal-title":"Turk J Gastroenterol"},{"key":"ref87","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1097\/MPA.0b013e3181c3c954","volume":"39","author":"Lu","year":"2010","journal-title":"Pancreas"},{"key":"ref88","doi-asserted-by":"publisher","first-page":"106621","DOI":"10.1016\/j.ijsu.2022.106621","volume":"101","author":"Patil","year":"2022","journal-title":"Int J Surg"}],"container-title":["Journal of Inflammation Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=86665","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=86665","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T23:25:15Z","timestamp":1672961115000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/pathogenesis-and-therapy-of-coagulation-disorders-in-severe-acute-panc-peer-reviewed-fulltext-article-JIR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":88,"URL":"https:\/\/doi.org\/10.2147\/jir.s388216","relation":{},"ISSN":["1178-7031"],"issn-type":[{"value":"1178-7031","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]}}}