{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T15:08:51Z","timestamp":1780412931038,"version":"3.54.1"},"reference-count":65,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JIR"],"DOI":"10.2147\/jir.s411492","type":"journal-article","created":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T01:35:06Z","timestamp":1684373706000},"page":"2159-2166","source":"Crossref","is-referenced-by-count":9,"title":["Antigen Recognition and Immune Response to Acute and Chronic Hepatitis B Virus Infection"],"prefix":"10.2147","volume":"Volume 16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1467-2724","authenticated-orcid":true,"given":"Adane","family":"Adugna","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2053","DOI":"10.1016\/S0140-6736(14)60220-8","volume":"384","author":"Tr\u00e9po","year":"2014","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1002\/hep.21627","volume":"45","author":"Hoofnagle","year":"2007","journal-title":"Hepatology"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1002\/hep.21513","volume":"45","author":"Lok","year":"2007","journal-title":"Hepatology"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1743-422X-11-22","volume":"11","author":"Busca","year":"2014","journal-title":"Virol J"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"1754","DOI":"10.1136\/gutjnl-2011-301073","volume":"61","author":"Bertoletti","year":"2012","journal-title":"Gut"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"91","DOI":"10.3390\/v1020091","volume":"1","author":"Bertoletti","year":"2009","journal-title":"Viruses"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1111\/liv.12749","volume":"35","author":"Ferrari","year":"2015","journal-title":"Liver Inter"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1016\/j.mcna.2004.08.014","volume":"89","author":"Hayashi","year":"2005","journal-title":"Med Clin"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1002\/jmv.1890430210","volume":"43","author":"Fong","year":"1994","journal-title":"J Med Virol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1126\/science.284.5415.825","volume":"284","author":"Guidotti","year":"1999","journal-title":"Science"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1007\/s12016-014-8465-4","volume":"50","author":"Li","year":"2016","journal-title":"Clin Rev Allergy Immunol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1111\/j.1572-0241.2003.07179.x","volume":"98","author":"Ben-Ari","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.antiviral.2016.03.008","volume":"130","author":"Isorce","year":"2016","journal-title":"Antiviral Res"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.antiviral.2015.08.008","volume":"122","author":"Isorce","year":"2015","journal-title":"Antiviral Res"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1897","DOI":"10.1053\/j.gastro.2011.06.051","volume":"141","author":"Zhang","year":"2011","journal-title":"Gastroenterology"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1016\/j.intimp.2006.12.007","volume":"7","author":"Xiong","year":"2007","journal-title":"Int Immunopharmacol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"690","DOI":"10.4049\/jimmunol.1401659","volume":"194","author":"Chen","year":"2015","journal-title":"J Immunol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"e1003208","DOI":"10.1371\/journal.ppat.1003208","volume":"9","author":"Schurich","year":"2013","journal-title":"PLoS Pathog"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1479-5876-6-58","volume":"6","author":"Schultz-Thater","year":"2008","journal-title":"J Transl Med"},{"key":"ref20","first-page":"188","volume":"23","author":"Zhang","year":"2009","journal-title":"Zhonghua Shi Yan He Lin Chuang Bing du Xue Za Zhi"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"323","DOI":"10.3389\/fimmu.2017.00323","volume":"8","author":"Liu","year":"2017","journal-title":"Front Immunol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1089\/vim.2013.0067","volume":"27","author":"Sanchooli","year":"2014","journal-title":"Viral Immunol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.micpath.2014.07.010","volume":"74","author":"Li","year":"2014","journal-title":"Microb Pathog"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1002\/jmv.24306","volume":"88","author":"Sun","year":"2016","journal-title":"J Med Virol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1111\/sji.12097","volume":"78","author":"Ma","year":"2013","journal-title":"Scand J Immunol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1038\/nri723","volume":"2","author":"Figdor","year":"2002","journal-title":"Nat Rev Immunol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1016\/j.coi.2007.05.006","volume":"19","author":"Van Vliet","year":"2007","journal-title":"Curr Opin Immunol"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1002\/hep.20366","volume":"40","author":"van der Molen","year":"2004","journal-title":"Hepatology"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1111\/j.1440-1746.2004.03529.x","volume":"20","author":"Duan","year":"2005","journal-title":"J Gastroenterol Hepatol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1046\/j.1365-2893.2003.00435.x","volume":"10","author":"Bozdayi","year":"2003","journal-title":"J Viral Hepat"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1038\/ni.2691","volume":"14","author":"Jenne","year":"2013","journal-title":"Nat Immunol"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1038\/cmi.2015.111","volume":"14","author":"Hou","year":"2017","journal-title":"Cell Mol Immunol"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"7654","DOI":"10.4049\/jimmunol.1000927","volume":"185","author":"Wang","year":"2010","journal-title":"J Immunol"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"3100","DOI":"10.4049\/jimmunol.1500839","volume":"195","author":"Li","year":"2015","journal-title":"J Immunol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"805","DOI":"10.4049\/jimmunol.1800871","volume":"202","author":"Hu","year":"2019","journal-title":"J Immunol"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"15142","DOI":"10.1128\/JVI.79.24.15142-15150.2005","volume":"79","author":"Takai","year":"2005","journal-title":"J Virol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1038\/cmi.2014.2","volume":"11","author":"Xu","year":"2014","journal-title":"Cell Mol Immunol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1034\/j.1600-0528.2002.017416.x","volume":"174","author":"Doherty","year":"2000","journal-title":"Immunol Rev"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1111\/j.1365-2893.2005.00543.x","volume":"12","author":"Chen","year":"2005","journal-title":"J Viral Hepat"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/j.bjid.2015.05.006","volume":"19","author":"Wu","year":"2015","journal-title":"Braz J Infect Dis"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"258","DOI":"10.3389\/fimmu.2014.00258","volume":"5","author":"Schuch","year":"2014","journal-title":"Front Immunol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1002\/hep.22034","volume":"47","author":"Gao","year":"2008","journal-title":"Hepatology"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/hep.23977","volume":"53","author":"Zhang","year":"2011","journal-title":"Hepatology"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"1984","DOI":"10.1002\/pro.3519","volume":"27","author":"Morris","year":"2018","journal-title":"Prot Sci"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1038\/cmi.2015.25","volume":"12","author":"Xu","year":"2015","journal-title":"Cell Mol Immunol"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"8766","DOI":"10.1073\/pnas.1003854107","volume":"107","author":"Farci","year":"2010","journal-title":"Proc Natl Acad Sci"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"e1003730","DOI":"10.1371\/journal.pcbi.1003730","volume":"10","author":"Ciupe","year":"2014","journal-title":"PLoS Comput Biol"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"1269","DOI":"10.1084\/jem.191.8.1269","volume":"191","author":"Maini","year":"2000","journal-title":"J Exp Med"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"2617","DOI":"10.1128\/JVI.76.6.2617-2621.2002","volume":"76","author":"Guidotti","year":"2002","journal-title":"J Virol"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1084\/jem.20112741","volume":"209","author":"Yokosuka","year":"2012","journal-title":"J Exp Med"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1038\/nri.2017.108","volume":"18","author":"Sharpe","year":"2018","journal-title":"Nat Rev Immunol"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1038\/ni.1679","volume":"10","author":"Blackburn","year":"2009","journal-title":"Nat Immunol"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1016\/j.molimm.2007.07.038","volume":"45","author":"Peng","year":"2008","journal-title":"Mol Immunol"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"101","DOI":"10.22578\/IJMS.18.2.3","volume":"18","author":"Mahdi","year":"2020","journal-title":"Iraqi JMS"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.3390\/ijms18071517","volume":"18","author":"Cho","year":"2017","journal-title":"Int J Mol Sci"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1128\/JVI.77.1.68-76.2003","volume":"77","author":"Thimme","year":"2003","journal-title":"J Virol"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"1472","DOI":"10.1172\/JCI119308","volume":"99","author":"Chisari","year":"1997","journal-title":"J Clin Invest"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"287","DOI":"10.4049\/jimmunol.0902761","volume":"184","author":"Phillips","year":"2010","journal-title":"J Immunol"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"1040","DOI":"10.1002\/hep.1840220405","volume":"22","author":"Marinos","year":"1995","journal-title":"Hepatology"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1111\/j.1365-2893.1997.tb00180.x","volume":"4","author":"Milich","year":"1997","journal-title":"J Viral Hepat"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"885","DOI":"10.3892\/etm.2012.864","volume":"5","author":"Xing","year":"2013","journal-title":"Exp Ther Med"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1111\/j.1365-2567.2007.02691.x","volume":"123","author":"Peng","year":"2008","journal-title":"Immunology"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"739","DOI":"10.4049\/jimmunol.177.1.739","volume":"177","author":"Xu","year":"2006","journal-title":"J Immunol"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/3-7643-7301-6_8","volume":"2005","author":"Baecher-Allan","year":"2005","journal-title":"Regul T Cells Inflam"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.4049\/jimmunol.167.3.1137","volume":"167","author":"Piccirillo","year":"2001","journal-title":"J Immunol"}],"container-title":["Journal of Inflammation Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=89778","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=89778","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T01:35:12Z","timestamp":1684373712000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/antigen-recognition-and-immune-response-to-acute-and-chronic-hepatitis-peer-reviewed-fulltext-article-JIR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":65,"URL":"https:\/\/doi.org\/10.2147\/jir.s411492","relation":{},"ISSN":["1178-7031"],"issn-type":[{"value":"1178-7031","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5]]}}}