{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:31:58Z","timestamp":1790746318274,"version":"4.1.0"},"reference-count":188,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JIR"],"DOI":"10.2147\/jir.s467099","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T04:15:14Z","timestamp":1716869714000},"page":"3433-3448","source":"Crossref","is-referenced-by-count":20,"title":["Association Between Atopic Dermatitis and Aging: Clinical Observations and Underlying Mechanisms"],"prefix":"10.2147","volume":"Volume 17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1041-4130","authenticated-orcid":true,"given":"Peng-Yu","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0441-9303","authenticated-orcid":true,"given":"Minxue","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7543-9013","authenticated-orcid":true,"given":"Sui-Qing","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7692-3501","authenticated-orcid":true,"given":"Zhen-Wei","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2024,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1016\/S0140-6736(20)31286-1","volume":"396","author":"Langan","year":"2020","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41572-018-0001-z","volume":"4","author":"Weidinger","year":"2018","journal-title":"Nat Rev Dis Primers"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"S58","DOI":"10.1016\/j.jaci.2017.01.008","volume":"139","author":"Bieber","year":"2017","journal-title":"J Allergy Clin Immunol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1111\/ggi.12771","volume":"16 Suppl 1","author":"Tanei","year":"2016","journal-title":"Geriatrics Gerontol Int"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1097\/ACI.0000000000000837","volume":"22","author":"Patruno","year":"2022","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/j.anai.2018.11.025","volume":"122","author":"Brunner","year":"2019","journal-title":"Ann Allergy Asthma Immunol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"2346","DOI":"10.1111\/jdv.16346","volume":"34","author":"Wang","year":"2020","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1111\/bjd.18652","volume":"182","author":"Williamson","year":"2020","journal-title":"Br J Dermatol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"2202","DOI":"10.1111\/all.15741","volume":"78","author":"Facheris","year":"2023","journal-title":"Allergy"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/j.anai.2021.03.001","volume":"127","author":"Pan","year":"2021","journal-title":"Ann Allergy Asthma Immunol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"24228","DOI":"10.1038\/s41598-021-03630-z","volume":"11","author":"Kim","year":"2021","journal-title":"Sci Rep"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"2232","DOI":"10.1111\/all.15807","volume":"78","author":"Shin","year":"2023","journal-title":"Allergy"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1753","DOI":"10.1016\/j.jaci.2020.12.001","volume":"147","author":"Silverwood","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"ref14","volume-title":"The Epidemiology of Aging","year":"2012"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1111\/j.1365-2133.2006.07659.x","volume":"156","author":"Wolkewitz","year":"2007","journal-title":"Br J Dermatol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1159\/000329150","volume":"157","author":"Bozek","year":"2012","journal-title":"Int Arch Allergy Immunol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1046\/j.1365-2133.2003.05092.x","volume":"148","author":"Muto","year":"2003","journal-title":"Br J Dermatol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1111\/ijd.14891","volume":"59","author":"Chello","year":"2020","journal-title":"Int J Dermatol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"278","DOI":"10.3345\/cep.2019.01291","volume":"63","author":"Ha","year":"2020","journal-title":"Clin Experim Pediatr"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1038\/s41586-019-1365-2","volume":"571","author":"Campisi","year":"2019","journal-title":"Nature"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"354","DOI":"10.7326\/M18-2246","volume":"170","author":"Abuabara","year":"2019","journal-title":"Ann Internal Med"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"adv00738","DOI":"10.2340\/actadv.v102.2287","volume":"102","author":"Salava","year":"2022","journal-title":"Acta Derm Venereol"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3390\/cells11162541","volume":"11","author":"Kim","year":"2022","journal-title":"Cells"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.clindermatol.2010.07.001","volume":"29","author":"Zouboulis","year":"2011","journal-title":"Clin Dermatol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1186\/s12935-023-03012-7","volume":"23","author":"Khayyati Kohnehshahri","year":"2023","journal-title":"Can Cell Inter"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"132","DOI":"10.3390\/life12010132","volume":"12","author":"Montero-Vilchez","year":"2022","journal-title":"Life"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1524","DOI":"10.1111\/all.15569","volume":"78","author":"Yin","year":"2022","journal-title":"Allergy"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1046\/j.1365-2133.2002.04765.x","volume":"147","author":"Eishi","year":"2002","journal-title":"Br J Dermatol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"4703","DOI":"10.1038\/s41467-019-12253-y","volume":"10","author":"Fyhrquist","year":"2019","journal-title":"Nat Commun"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1038\/s41591-021-01256-2","volume":"27","author":"Nakatsuji","year":"2021","journal-title":"Nature Med"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1111\/all.16077","author":"Kim","year":"2024","journal-title":"Allergy"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1111\/jdv.18663","volume":"37","author":"Ju","year":"2023","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref33","first-page":"239","volume":"27","author":"Masoro","year":"2012","journal-title":"Handbook Biol Aging"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1161\/01.ATV.0000160548.78317.29","volume":"25","author":"Zieman","year":"2005","journal-title":"Arteriosclerosis Thrombosis Vasc Biol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.jid.2016.08.022","volume":"137","author":"Brunner","year":"2017","journal-title":"J Investigat Dermatol"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"956850","DOI":"10.3389\/fgene.2022.956850","volume":"13","author":"Huang","year":"2022","journal-title":"Front Genetics"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1111\/bjd.20802","volume":"186","author":"Ben Abdallah","year":"2022","journal-title":"Br J Dermatol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1111\/bjd.15727","volume":"177","author":"Drucker","year":"2017","journal-title":"Br J Dermatol"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1016\/j.jid.2016.11.031","volume":"137","author":"Standl","year":"2017","journal-title":"J Investigat Dermatol"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1111\/bjd.20661","volume":"186","author":"Yousaf","year":"2022","journal-title":"Br J Dermatol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1016\/j.jaad.2019.10.039","volume":"82","author":"Pavel","year":"2020","journal-title":"J Am Acad Dermatol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1016\/j.jaad.2020.04.138","volume":"84","author":"Glickman","year":"2021","journal-title":"J Am Acad Dermatol"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"3107","DOI":"10.1111\/all.14859","volume":"76","author":"Villani","year":"2021","journal-title":"Allergy"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.jaad.2023.05.031","volume":"89","author":"Smith","year":"2023","journal-title":"J Am Acad Dermatol"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.annepidem.2005.06.052","volume":"16","author":"Segal","year":"2006","journal-title":"Ann epidemiol"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1007\/s00335-016-9629-8","volume":"27","author":"Jones","year":"2016","journal-title":"Mammalian Genome"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.exger.2007.06.014","volume":"43","author":"Mari","year":"2008","journal-title":"Exp Gerontology"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1161\/CIRCRESAHA.111.300539","volume":"112","author":"Willeit","year":"2013","journal-title":"Circ Res"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"e0277469","DOI":"10.1371\/journal.pone.0277469","volume":"17","author":"Hedderson","year":"2022","journal-title":"PLoS One"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1016\/j.amjmed.2014.03.041","volume":"127","author":"Huang","year":"2014","journal-title":"Am j Med"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1001\/jamadermatol.2023.1300","volume":"159","author":"Chen","year":"2023","journal-title":"JAMA Dermatol"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1016\/S2213-8587(18)30026-3","volume":"6","author":"van den Beld","year":"2018","journal-title":"Lancet Diabetes Endocrinol"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1093\/ageing\/20.3.221","volume":"20","author":"Broughton","year":"1991","journal-title":"Age Ageing"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"e000062","DOI":"10.1136\/bmjopen-2011-000062","volume":"1","author":"Thyssen","year":"2011","journal-title":"BMJ open"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1016\/j.jaci.2014.11.023","volume":"135","author":"Silverberg","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1016\/j.jaci.2016.08.049","volume":"139","author":"Andersen","year":"2017","journal-title":"J Allergy Clin Immunol"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1111\/bjd.16215","volume":"178","author":"Thyssen","year":"2018","journal-title":"Br J Dermatol"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"2161","DOI":"10.1111\/dom.14146","volume":"22","author":"Gether","year":"2020","journal-title":"Diabetes Obes Metab"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1016\/j.jaad.2022.12.050","volume":"88","author":"Del Duca","year":"2023","journal-title":"J Am Acad Dermatol"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.arr.2014.12.001","volume":"19","author":"Liu","year":"2015","journal-title":"Ageing Res Rev"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1161\/01.ATV.3.3.260","volume":"3","author":"Abbott","year":"1983","journal-title":"Arteriosclerosis"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1161\/01.CIR.96.1.37","volume":"96","author":"Ferrara","year":"1997","journal-title":"Circulation"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/0002-9343(87)90272-5","volume":"82","author":"Kreisberg","year":"1987","journal-title":"Am j Med"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1177\/1753944710385048","volume":"4","author":"Gobal","year":"2010","journal-title":"Therap Adv Cardiovasc Dis"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.1161\/ATVBAHA.108.181438","volume":"29","author":"Walter","year":"2009","journal-title":"Arteriosclerosis Thrombosis Vasc Biol"},{"key":"ref66","doi-asserted-by":"publisher","first-page":"810092","DOI":"10.3389\/fmed.2022.810092","volume":"9","author":"Tang","year":"2022","journal-title":"Front Med"},{"key":"ref67","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1038\/nrendo.2013.38","volume":"9","author":"Veldhuis","year":"2013","journal-title":"Nat Rev Endocrinol"},{"key":"ref68","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1038\/nrendo.2013.30","volume":"9","author":"Boelaert","year":"2013","journal-title":"Nat Rev Endocrinol"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1089\/rej.2017.1991","volume":"21","author":"Duntas","year":"2018","journal-title":"Rejuvenation Res"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1016\/j.jaad.2022.10.017","volume":"88","author":"Smith","year":"2022","journal-title":"J Am Acad Dermatol"},{"key":"ref71","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1038\/ng.2642","volume":"45","author":"Ellinghaus","year":"2013","journal-title":"Nature Genet"},{"key":"ref72","doi-asserted-by":"publisher","first-page":"906","DOI":"10.1210\/er.2018-00178","volume":"40","author":"Kaufman","year":"2019","journal-title":"Endocrine Reviews"},{"key":"ref73","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1007\/s10815-016-0663-y","volume":"33","author":"Gunes","year":"2016","journal-title":"J Assist Reprod Genet"},{"key":"ref74","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1016\/j.fertnstert.2013.05.046","volume":"100","author":"Stone","year":"2013","journal-title":"Fertil Sterility"},{"key":"ref75","doi-asserted-by":"publisher","first-page":"105","DOI":"10.5935\/1518-0557.20210026","volume":"26","author":"Moghadam","year":"2022","journal-title":"JBRA Assist Reprod"},{"key":"ref76","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.tem.2007.01.004","volume":"18","author":"Broekmans","year":"2007","journal-title":"Trends Endocrinol Metab"},{"key":"ref77","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1530\/rep.0.1230023","volume":"123","author":"Markstr\u00f6m","year":"2002","journal-title":"Reproduction"},{"key":"ref78","doi-asserted-by":"publisher","first-page":"1484","DOI":"10.1093\/oxfordjournals.humrep.a019422","volume":"11","author":"Faddy","year":"1996","journal-title":"Hum Reprod"},{"key":"ref79","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1093\/humupd\/8.2.141","volume":"8","author":"te Velde","year":"2002","journal-title":"Hum Reprod Update"},{"key":"ref80","first-page":"61","volume":"11","author":"Wood","year":"1989","journal-title":"Oxford RevReprod Biol"},{"key":"ref81","doi-asserted-by":"publisher","first-page":"305","DOI":"10.11622\/smedj.2014081","volume":"55","author":"Tan","year":"2014","journal-title":"Singapore Med J"},{"key":"ref82","doi-asserted-by":"publisher","first-page":"2066","DOI":"10.1016\/j.jaip.2022.04.002","volume":"10","author":"Weare-Regales","year":"2022","journal-title":"J Allergy Clin Immunol Pract"},{"key":"ref83","doi-asserted-by":"publisher","first-page":"113397","DOI":"10.1016\/j.jep.2020.113397","volume":"266","author":"Yuan","year":"2021","journal-title":"J Ethnopharmacol"},{"key":"ref84","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1111\/j.1346-8138.1996.tb02662.x","volume":"23","author":"Ebata","year":"1996","journal-title":"J Dermatol"},{"key":"ref85","first-page":"160","volume":"17","author":"Kasperska-Zajac","year":"2007","journal-title":"J Invest Allergol Clin Immunol"},{"key":"ref86","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1159\/000504388","volume":"236","author":"Vinnik","year":"2020","journal-title":"Dermatology"},{"key":"ref87","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1016\/j.jid.2021.07.133","volume":"142","author":"Kische","year":"2022","journal-title":"J Investigat Dermatol"},{"key":"ref88","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1016\/j.taap.2018.07.008","volume":"355","author":"Watanabe","year":"2018","journal-title":"Toxicol Appl Pharmacol"},{"key":"ref89","doi-asserted-by":"crossref","first-page":"e2100749118","DOI":"10.1073\/pnas.2100749118","volume":"118","author":"Zhang","year":"2021","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref90","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1007\/s40257-022-00677-0","volume":"23","author":"Ng","year":"2022","journal-title":"Am J Clin Dermatol"},{"key":"ref91","doi-asserted-by":"publisher","first-page":"308","DOI":"10.5534\/wjmh.200156","volume":"40","author":"Costanzo","year":"2022","journal-title":"World J Mens Health"},{"key":"ref92","doi-asserted-by":"publisher","first-page":"90","DOI":"10.3390\/biomedicines11010090","volume":"11","author":"Adamczewska","year":"2022","journal-title":"Biomedicines"},{"key":"ref93","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/s13293-021-00358-3","volume":"12","author":"Dupuis","year":"2021","journal-title":"Biol Sex Diff"},{"key":"ref94","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1159\/000515600","volume":"238","author":"Horev","year":"2022","journal-title":"Dermatology"},{"key":"ref95","doi-asserted-by":"publisher","first-page":"101157","DOI":"10.1016\/j.mam.2022.101157","volume":"88","author":"Weinberg","year":"2022","journal-title":"Mol Aspect Med"},{"key":"ref96","doi-asserted-by":"publisher","first-page":"e489","DOI":"10.1016\/S2214-109X(20)30488-5","volume":"9","author":"Burton","year":"2021","journal-title":"Lancet Glob Health"},{"key":"ref97","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1001\/archopht.122.4.477","volume":"122","author":"Congdon","year":"2004","journal-title":"Arch Ophthalmol"},{"key":"ref98","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.clae.2017.05.003","volume":"40","author":"Hashemi","year":"2017","journal-title":"Contact Lens Anterior Eye"},{"key":"ref99","doi-asserted-by":"publisher","first-page":"1283","DOI":"10.1167\/iovs.16-21374","volume":"58","author":"Amano","year":"2017","journal-title":"Invest Ophthalmol Visual Sci"},{"key":"ref100","doi-asserted-by":"publisher","first-page":"e144","DOI":"10.1016\/S2214-109X(20)30489-7","volume":"9","author":"Steinmetz","year":"2021","journal-title":"Lancet Glob Health"},{"key":"ref101","doi-asserted-by":"publisher","first-page":"e2214610","DOI":"10.1001\/jamanetworkopen.2022.14610","volume":"5","author":"Varadaraj","year":"2022","journal-title":"JAMA network open"},{"key":"ref102","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1007\/s40257-019-00455-5","volume":"20","author":"Beck","year":"2019","journal-title":"Am J Clin Dermatol"},{"key":"ref103","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.1016\/S0161-6420(94)31219-X","volume":"101","author":"Oka","year":"1994","journal-title":"Ophthalmology"},{"key":"ref104","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1111\/j.1346-8138.1999.tb02068.x","volume":"26","author":"Taniguchi","year":"1999","journal-title":"J Dermatol"},{"key":"ref105","doi-asserted-by":"publisher","first-page":"33","DOI":"10.2500\/aap.2013.34.3612","volume":"34","author":"Sy","year":"2013","journal-title":"Allergy Asthma Proc"},{"key":"ref106","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.jaad.2017.03.003","volume":"77","author":"Thyssen","year":"2017","journal-title":"J Am Acad Dermatol"},{"key":"ref107","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/bs.afnr.2015.09.001","volume":"76","author":"Milan","year":"2015","journal-title":"Adv Food Nutr Res"},{"key":"ref108","doi-asserted-by":"publisher","first-page":"97","DOI":"10.3390\/life11020097","volume":"11","author":"Lerner","year":"2021","journal-title":"Life"},{"key":"ref109","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1097\/MCO.0000000000000238","volume":"19","author":"Soenen","year":"2016","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"ref110","doi-asserted-by":"publisher","first-page":"e14352","DOI":"10.1111\/nmo.14352","volume":"34","author":"Nguyen","year":"2022","journal-title":"Neurogastroenterol Motil"},{"key":"ref111","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/s12979-020-00213-w","volume":"18","author":"Ragonnaud","year":"2021","journal-title":"Immunity Ageing"},{"key":"ref112","doi-asserted-by":"publisher","first-page":"355","DOI":"10.4103\/ijd.IJD_490_18","volume":"64","author":"Islamo\u011flu ZG","year":"2019","journal-title":"Indian J Dermatol"},{"key":"ref113","doi-asserted-by":"publisher","first-page":"44385","DOI":"10.1038\/srep44385","volume":"7","author":"Zachariassen","year":"2017","journal-title":"Sci Rep"},{"key":"ref114","doi-asserted-by":"publisher","first-page":"2044723","DOI":"10.1080\/19490976.2022.2044723","volume":"14","author":"Fang","year":"2022","journal-title":"Gut Microbes"},{"key":"ref115","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1210\/er.2009-0024","volume":"31","author":"Manolagas","year":"2010","journal-title":"Endocrine Reviews"},{"key":"ref116","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1111\/j.1474-9726.2011.00669.x","volume":"10","author":"Kassem","year":"2011","journal-title":"Aging Cell"},{"key":"ref117","doi-asserted-by":"publisher","first-page":"2636","DOI":"10.1016\/S0140-6736(19)31138-9","volume":"393","author":"Cruz-Jentoft","year":"2019","journal-title":"Lancet"},{"key":"ref118","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1007\/s43657-023-00110-4","volume":"4","author":"Tang","year":"2023","journal-title":"Phenomics"},{"key":"ref119","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1016\/j.jaad.2018.05.026","volume":"80","author":"Shaheen","year":"2019","journal-title":"J Am Acad Dermatol"},{"key":"ref120","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1016\/j.anai.2021.09.004","volume":"127","author":"Lin","year":"2021","journal-title":"Ann Allergy Asthma Immunol"},{"key":"ref121","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1016\/j.jaci.2022.12.002","volume":"151","author":"Thyssen","year":"2023","journal-title":"J Allergy Clin Immunol"},{"key":"ref122","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1111\/jdv.16895","volume":"35","author":"Mukovozov","year":"2021","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref123","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.1016\/j.jaad.2022.01.009","volume":"86","author":"Davis","year":"2022","journal-title":"J Am Acad Dermatol"},{"key":"ref124","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1038\/nrn.2017.42","volume":"18","author":"Satoh","year":"2017","journal-title":"Nat Rev Neurosci"},{"key":"ref125","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/S0304-3940(01)02428-4","volume":"317","author":"Page","year":"2002","journal-title":"Neurosci Lett"},{"key":"ref126","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1093\/cercor\/13.9.950","volume":"13","author":"Duan","year":"2003","journal-title":"Cereb. Cortex"},{"key":"ref127","doi-asserted-by":"publisher","first-page":"4373","DOI":"10.1523\/JNEUROSCI.4289-03.2004","volume":"24","author":"Smith","year":"2004","journal-title":"J Neurosci"},{"key":"ref128","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1515\/revneuro-2018-0084","volume":"30","author":"Isaev","year":"2019","journal-title":"Rev Neurosci"},{"key":"ref129","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.arr.2018.09.005","volume":"48","author":"Chadda","year":"2018","journal-title":"Ageing Res Rev"},{"key":"ref130","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.ydbio.2013.03.015","volume":"382","author":"Saffrey","year":"2013","journal-title":"Dev Biol"},{"key":"ref131","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1016\/j.jaad.2020.05.041","volume":"83","author":"Silverberg","year":"2020","journal-title":"J Am Acad Dermatol"},{"key":"ref132","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1016\/j.anai.2020.11.008","volume":"126","author":"Jackson-Cowan","year":"2021","journal-title":"Ann Allergy Asthma Immunol"},{"key":"ref133","doi-asserted-by":"publisher","first-page":"1913","DOI":"10.3390\/healthcare10101913","volume":"10","author":"Birdi","year":"2022","journal-title":"Healthcare"},{"key":"ref134","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1016\/j.jaad.2021.11.014","volume":"86","author":"Roh","year":"2022","journal-title":"J Am Acad Dermatol"},{"key":"ref135","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1365-2567.2011.03506.x","volume":"135","author":"Moens","year":"2012","journal-title":"Immunology"},{"key":"ref136","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.1016\/j.jaci.2020.04.024","volume":"145","author":"Celebi S\u00f6zener","year":"2020","journal-title":"J Allergy Clin Immunol"},{"key":"ref137","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.jaci.2012.12.1563","volume":"131","author":"Kuo","year":"2013","journal-title":"J Allergy Clin Immunol"},{"key":"ref138","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1111\/ijd.15814","volume":"61","author":"Suwanchote","year":"2022","journal-title":"Int J Dermatol"},{"key":"ref139","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/j.chom.2022.01.004","volume":"30","author":"Zheng","year":"2022","journal-title":"Cell Host Microbe"},{"key":"ref140","doi-asserted-by":"publisher","first-page":"111761","DOI":"10.1016\/j.mad.2022.111761","volume":"210","author":"Lin","year":"2023","journal-title":"Mech Ageing Dev"},{"key":"ref141","doi-asserted-by":"publisher","first-page":"5551","DOI":"10.18632\/aging.102946","volume":"12","author":"Wang","year":"2020","journal-title":"Aging"},{"key":"ref142","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/s12979-023-00331-1","volume":"20","author":"Yang","year":"2023","journal-title":"Immunity Ageing"},{"key":"ref143","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1159\/000231524","volume":"22","author":"Man","year":"2009","journal-title":"Skin Pharmacol Physiol"},{"key":"ref144","doi-asserted-by":"publisher","first-page":"2847","DOI":"10.1038\/sj.jid.5700913","volume":"127","author":"Choi","year":"2007","journal-title":"J Investigat Dermatol"},{"key":"ref145","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1038\/jid.2013.402","volume":"134","author":"V\u00e1vrov\u00e1","year":"2014","journal-title":"J Investigat Dermatol"},{"key":"ref146","doi-asserted-by":"publisher","first-page":"1292","DOI":"10.1111\/all.15640","volume":"78","author":"Kim","year":"2023","journal-title":"Allergy"},{"key":"ref147","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1111\/bjd.16734","volume":"179","author":"Zhu","year":"2018","journal-title":"Br J Dermatol"},{"key":"ref148","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1186\/s40168-022-01386-w","volume":"10","author":"Kim","year":"2022","journal-title":"Microbiome"},{"key":"ref149","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1111\/j.1749-6632.2000.tb06651.x","volume":"908","author":"Franceschi","year":"2000","journal-title":"Ann N Y Acad Sci"},{"key":"ref150","doi-asserted-by":"publisher","first-page":"2974","DOI":"10.1093\/eurheartj\/ehz961","volume":"41","author":"Liberale","year":"2020","journal-title":"Eur Heart J"},{"key":"ref151","doi-asserted-by":"publisher","first-page":"943640","DOI":"10.3389\/fimmu.2022.943640","volume":"13","author":"Ong","year":"2022","journal-title":"Front Immunol"},{"key":"ref152","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.mad.2017.07.001","volume":"170","author":"de Magalh\u00e3es","year":"2018","journal-title":"Mech Ageing Dev"},{"key":"ref153","doi-asserted-by":"publisher","first-page":"16981","DOI":"10.3390\/ijms160816981","volume":"16","author":"S\u00e1nchez","year":"2015","journal-title":"Int J Mol Sci"},{"key":"ref154","doi-asserted-by":"publisher","first-page":"59","DOI":"10.3389\/fcell.2020.00059","volume":"8","author":"Wang","year":"2020","journal-title":"Front Cell Develop Biol"},{"key":"ref155","doi-asserted-by":"publisher","first-page":"2853","DOI":"10.1371\/journal.pbio.0060301","volume":"6","author":"Copp\u00e9","year":"2008","journal-title":"PLoS biol"},{"key":"ref156","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.brainresrev.2007.02.007","volume":"54","author":"Pardon","year":"2007","journal-title":"Brain Res Rev"},{"key":"ref157","doi-asserted-by":"publisher","first-page":"9631","DOI":"10.1007\/s11357-014-9631-6","volume":"36","author":"Vitlic","year":"2014","journal-title":"Age"},{"key":"ref158","doi-asserted-by":"publisher","first-page":"2131","DOI":"10.3390\/ijms18102131","volume":"18","author":"Lin","year":"2017","journal-title":"Int J Mol Sci"},{"key":"ref159","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1001\/jamapsychiatry.2019.4188","volume":"77","author":"Bahrami","year":"2020","journal-title":"JAMA psychiatry"},{"key":"ref160","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1038\/s41562-020-01031-2","volume":"5","author":"Bahrami","year":"2021","journal-title":"Nat Human Behav"},{"key":"ref161","doi-asserted-by":"publisher","first-page":"775591","DOI":"10.3389\/fgene.2021.775591","volume":"12","author":"Zhou","year":"2021","journal-title":"Front Genetics"},{"key":"ref162","doi-asserted-by":"publisher","first-page":"1495","DOI":"10.1016\/j.jaci.2019.10.023","volume":"144","author":"Schoettler","year":"2019","journal-title":"J Allergy Clin Immunol"},{"key":"ref163","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.humimm.2020.11.005","volume":"82","author":"Restrepo","year":"2021","journal-title":"Hum Immunol"},{"key":"ref164","doi-asserted-by":"publisher","first-page":"2316","DOI":"10.18632\/aging.101323","volume":"9","author":"Yang","year":"2017","journal-title":"Aging"},{"key":"ref165","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1038\/35041700","volume":"408","author":"Guarente","year":"2000","journal-title":"Nature"},{"key":"ref166","doi-asserted-by":"publisher","first-page":"1037925","DOI":"10.3389\/fphar.2023.1037925","volume":"14","author":"Xiao","year":"2023","journal-title":"Front Pharmacol"},{"key":"ref167","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1002\/med.20178","volume":"30","author":"Schemies","year":"2010","journal-title":"Med Res Rev"},{"key":"ref168","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1186\/1479-7364-5-5-485","volume":"5","author":"Vassilopoulos","year":"2011","journal-title":"Hum Genomics"},{"key":"ref169","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1016\/j.cell.2019.03.043","volume":"177","author":"Tian","year":"2019","journal-title":"Cell"},{"key":"ref170","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1016\/j.jaci.2014.09.035","volume":"135","author":"Ming","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"ref171","doi-asserted-by":"publisher","first-page":"1504","DOI":"10.1172\/JCI124612","volume":"129","author":"Murrison","year":"2019","journal-title":"J Clin Invest"},{"key":"ref172","doi-asserted-by":"publisher","first-page":"113932","DOI":"10.1016\/j.ijheh.2022.113932","volume":"241","author":"Tang","year":"2022","journal-title":"Int J Hygiene Environ Health"},{"key":"ref173","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1111\/pai.13471","volume":"32","author":"Mahdavinia","year":"2021","journal-title":"Pediatr Allergy Immunol"},{"key":"ref174","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/S0091-6749(00)90069-1","volume":"105","author":"Weinberg","year":"2000","journal-title":"J Allergy Clin Immunol"},{"key":"ref175","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.3390\/ijerph14121458","volume":"14","author":"Ngoc","year":"2017","journal-title":"Int J Environ Res Public Health"},{"key":"ref176","doi-asserted-by":"publisher","first-page":"92","DOI":"10.4103\/ijd.IJD_520_18","volume":"65","author":"Li","year":"2020","journal-title":"Indian J Dermatol"},{"key":"ref177","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.145185","volume":"6","author":"Kim","year":"2021","journal-title":"JCI Insight"},{"key":"ref178","doi-asserted-by":"publisher","first-page":"1160","DOI":"10.1001\/jamapediatrics.2017.3024","volume":"171","author":"Martens","year":"2017","journal-title":"JAMA Pediatr"},{"key":"ref179","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1001\/jamaneurol.2019.4914","volume":"77","author":"Grande","year":"2020","journal-title":"JAMA neurol"},{"key":"ref180","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1093\/brain\/awz348","volume":"143","author":"Younan","year":"2020","journal-title":"Brain"},{"key":"ref181","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1080\/09603123.2019.1682528","volume":"31","author":"Wu","year":"2021","journal-title":"Int J Environ Health Res"},{"key":"ref182","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1016\/j.ad.2019.03.018","volume":"111","author":"Marron","year":"2020","journal-title":"Actas Dermo-Sifiliograficas"},{"key":"ref183","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1542\/peds.2004-0374","volume":"114","author":"Chamlin","year":"2004","journal-title":"Pediatrics"},{"key":"ref184","doi-asserted-by":"publisher","first-page":"919","DOI":"10.2147\/JAA.S317009","volume":"14","author":"Stingeni","year":"2021","journal-title":"J Asthma Allergy"},{"key":"ref185","doi-asserted-by":"publisher","first-page":"S119","DOI":"10.3233\/JAD-180501","volume":"70","author":"Evans","year":"2019","journal-title":"J Alzheimers Dis"},{"key":"ref186","doi-asserted-by":"publisher","first-page":"1619","DOI":"10.3233\/JAD-180439","volume":"66","author":"Penninkilampi","year":"2018","journal-title":"J Alzheimers Dis"},{"key":"ref187","doi-asserted-by":"publisher","first-page":"1387","DOI":"10.1177\/2047487318792696","volume":"25","author":"Valtorta","year":"2018","journal-title":"Eur J Prevent Cardiol"},{"key":"ref188","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1080\/1744666X.2024.2301967","volume":"20","author":"Napolitano","year":"2024","journal-title":"Expert Rev Clin Immunol"}],"container-title":["Journal of Inflammation Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=99495","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=99495","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T04:15:25Z","timestamp":1716869725000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/association-between-atopic-dermatitis-and-aging-clinical-observations--peer-reviewed-fulltext-article-JIR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":188,"URL":"https:\/\/doi.org\/10.2147\/jir.s467099","relation":{},"ISSN":["1178-7031"],"issn-type":[{"value":"1178-7031","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5]]}}}