{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T03:24:47Z","timestamp":1776914687062,"version":"3.51.2"},"reference-count":52,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JIR"],"DOI":"10.2147\/jir.s476646","type":"journal-article","created":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T03:55:14Z","timestamp":1728964514000},"page":"7361-7372","source":"Crossref","is-referenced-by-count":3,"title":["Clinical Observation of Hydrogen-Rich Saline for Nasal Irrigation After Surgery for Chronic sinusitis:A Randomized, Double-Blind, Controlled Trial"],"prefix":"10.2147","volume":"Volume 17","author":[{"given":"Ling","family":"Jin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunyan","family":"Yao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongjun","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiawei","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2208-4535","authenticated-orcid":true,"given":"Shaoqing","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2024,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4193\/Rhin20.600","volume":"58","author":"Fokkens","year":"2020","journal-title":"Rhinology"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1001\/jamaoto.2015.3142","volume":"142","author":"Ahn","year":"2016","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1002\/alr.22034","volume":"8","author":"Yoo","year":"2018","journal-title":"Int Forum Allergy Rhinol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.anai.2021.10.014","volume":"128","author":"Borish","year":"2022","journal-title":"Ann Allergy Asthma Immunol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1017\/S002221512100030X","volume":"135","author":"Fandino","year":"2021","journal-title":"J Laryngol Otol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"245","DOI":"10.3390\/jpm10040245","volume":"10","author":"Michalik","year":"2020","journal-title":"J Pers Med"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"187","DOI":"10.5415\/apallergy.0000000000000120","volume":"13","author":"Jin","year":"2023","journal-title":"Asia Pac Allergy"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"302","DOI":"10.4193\/Rhino16.026","volume":"54","author":"Giotakis","year":"2016","journal-title":"Rhinology"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1016\/j.bjorl.2020.03.008","volume":"86","author":"Liu","year":"2020","journal-title":"Braz J Otorhinolaryngol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1007\/s12070-020-01878-x","volume":"72","author":"Thanneru","year":"2020","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"102604","DOI":"10.1016\/j.amjoto.2020.102604","volume":"41","author":"Lee","year":"2020","journal-title":"Am J Otolaryngol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1470","DOI":"10.1002\/alr.22423","volume":"9","author":"Ooi","year":"2019","journal-title":"Int Forum Allergy Rhinol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1001\/jamaoto.2019.1191","volume":"145","author":"Ooi","year":"2019","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"7785","DOI":"10.3390\/molecules28237785","volume":"28","author":"Johnsen","year":"2023","journal-title":"Molecules"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"2062","DOI":"10.3390\/antiox12122062","volume":"12","author":"Cheng","year":"2023","journal-title":"Antioxidants (Basel)"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"946","DOI":"10.2174\/1381612825666190506123038","volume":"25","author":"Ishibashi","year":"2019","journal-title":"Curr Pharm Des"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"2149","DOI":"10.2147\/JIR.S413179","volume":"16","author":"Jin","year":"2023","journal-title":"J Inflamm Res"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2023.128901","author":"Zhu","year":"2023","journal-title":"Int J Biol Macromol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"2076","DOI":"10.3390\/molecules24112076","volume":"24","author":"LeBaron","year":"2019","journal-title":"Molecules"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1007\/s11481-022-10051-w","volume":"18","author":"Yang","year":"2023","journal-title":"J Neuroimmune Pharmacol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1007\/s10753-017-0666-6","volume":"41","author":"Xu","year":"2018","journal-title":"Inflammation"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12950-016-0148-x","volume":"14","author":"Yu","year":"2017","journal-title":"J Inflamm"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1016\/j.aller.2016.10.007","volume":"45","author":"Zhao","year":"2017","journal-title":"Allergol Immunopathol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"3983","DOI":"10.2147\/JIR.S365611","volume":"15","author":"Jin","year":"2022","journal-title":"J Inflamm Res"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.3892\/ijmm.2019.4264","volume":"44","author":"Yao","year":"2019","journal-title":"Int J Mol Med"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1038\/nm1577","volume":"13","author":"Ohsawa","year":"2007","journal-title":"Nat Med"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1177\/000348949510410s02","volume":"167","author":"Lund","year":"1995","journal-title":"Ann Otol Rhinol Laryngol Suppl"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.1016\/j.jaci.2015.10.012","volume":"136","author":"Rudmik","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1111\/j.1749-4486.2009.01995.x","volume":"34","author":"Hopkins","year":"2009","journal-title":"Clin Otolaryngol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.anai.2018.10.014","volume":"122","author":"Cao","year":"2019","journal-title":"Ann Allergy Asthma Immunol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1491","DOI":"10.1016\/j.jaci.2022.02.016","volume":"149","author":"Kato","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1080\/00016480310005110","volume":"123","author":"Toskala","year":"2003","journal-title":"Acta Otolaryngol"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"971","DOI":"10.3109\/10715762.2010.500328","volume":"44","author":"Huang","year":"2010","journal-title":"Free Radic Res"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"2114","DOI":"10.3892\/etm.2015.2385","volume":"9","author":"Zhang","year":"2015","journal-title":"Exp Ther Med"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"5178","DOI":"10.3892\/etm.2018.6880","volume":"16","author":"Fang","year":"2018","journal-title":"Exp Ther Med"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"98","DOI":"10.3390\/antiox7080098","volume":"7","author":"Cano Sanchez","year":"2018","journal-title":"Antioxidants"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1524-475X.2008.00436.x","volume":"17","author":"Sen","year":"2009","journal-title":"Wound Repair Regen"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1111\/iwj.12557","volume":"14","author":"Dunnill","year":"2017","journal-title":"Int Wound J"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1016\/j.redox.2015.01.002","volume":"4","author":"Sies","year":"2015","journal-title":"Redox Biol"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1007\/s00204-013-1034-4","volume":"87","author":"Sinha","year":"2013","journal-title":"Arch Toxicol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"5857","DOI":"10.1111\/jcmm.16597","volume":"25","author":"Liu","year":"2021","journal-title":"J Cell Mol Med"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"2424","DOI":"10.3390\/molecules26092424","volume":"26","author":"S\u00fcntar","year":"2021","journal-title":"Molecules"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"3856","DOI":"10.3390\/ijms20163856","volume":"20","author":"Hiebert","year":"2019","journal-title":"Int J Mol Sci"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"2949824","DOI":"10.1155\/2022\/2949824","volume":"2022","author":"Li","year":"2022","journal-title":"Oxid Med Cell Longev"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/s41232-023-00271-9","volume":"43","author":"Zhao","year":"2023","journal-title":"Inflamm Regen"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"9774","DOI":"10.3390\/ijms23179774","volume":"23","author":"Kasamatsu","year":"2022","journal-title":"Int J Mol Sci"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"264","DOI":"10.3390\/vetsci8110264","volume":"8","author":"Qi","year":"2021","journal-title":"Vet Sci"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"1104444","DOI":"10.3389\/fcimb.2023.1104444","volume":"13","author":"Zhou","year":"2023","journal-title":"Front Cell Infect Microbiol"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1111\/all.12983","volume":"72","author":"van der Veen","year":"2017","journal-title":"Allergy"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"103406","DOI":"10.1016\/j.amjoto.2022.103406","volume":"43","author":"Wang","year":"2022","journal-title":"Am J Otolaryngol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"1584","DOI":"10.1002\/alr.23127","volume":"13","author":"Khanwalkar","year":"2023","journal-title":"Int Forum Allergy Rhinol"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"CD012597","DOI":"10.1002\/14651858.CD012597.pub2","volume":"6","author":"Head","year":"2018","journal-title":"Cochrane Database Syst Rev"}],"container-title":["Journal of Inflammation Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/96417","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/96417","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T03:55:17Z","timestamp":1728964517000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/clinical-observation-of-hydrogen-rich-saline-for-nasal-irrigation-afte-peer-reviewed-fulltext-article-JIR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":52,"URL":"https:\/\/doi.org\/10.2147\/jir.s476646","relation":{},"ISSN":["1178-7031"],"issn-type":[{"value":"1178-7031","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10]]}}}