{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:42:53Z","timestamp":1790127773795,"version":"4.0.1"},"reference-count":47,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JIR"],"DOI":"10.2147\/jir.s505296","type":"journal-article","created":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T10:40:27Z","timestamp":1738147227000},"page":"1353-1375","source":"Crossref","is-referenced-by-count":8,"title":["CLEC11A-Driven Molecular Mechanisms in Intervertebral Disc Degeneration: A Comprehensive Multi-Omics Study"],"prefix":"10.2147","volume":"Volume 18","author":[{"given":"Nizhou","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quanxiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenxin","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9703-2743","authenticated-orcid":true,"given":"Xiliang","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,1]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1007\/s11914-022-00769-0","volume":"21","author":"Ou-Yang","year":"2023","journal-title":"Curr Osteoporosis Rep"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1016\/j.bioactmat.2024.07.031","volume":"41","author":"Wang","year":"2024","journal-title":"Bioact Mater"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1038\/nrrheum.2015.13","volume":"11","author":"Sakai","year":"2015","journal-title":"Nat Rev Rheumatol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1515\/revneuro-2014-0077","volume":"26","author":"Hanaei","year":"2015","journal-title":"Rev Neurosci"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.gendis.2016.04.005","volume":"3","author":"Feng","year":"2016","journal-title":"Genes Dis"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.jot.2023.01.001","volume":"39","author":"Lu","year":"2023","journal-title":"J Orthop Translat"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1001\/jama.2016.21189","volume":"317","author":"Davey Smith","year":"2017","journal-title":"JAMA"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1186\/s13073-021-00890-2","volume":"13","author":"Gockley","year":"2021","journal-title":"Genome Med"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1007\/s10654-021-00757-1","volume":"36","author":"Carter","year":"2021","journal-title":"Eur J Epidemiol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1300","DOI":"10.1038\/s41588-021-00913-z","volume":"53","author":"V\u00f5sa","year":"2021","journal-title":"Nature Genet"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1540","DOI":"10.1038\/s41590-023-01588-w","volume":"24","author":"Zhao","year":"2023","journal-title":"Nat Immunol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1038\/s41588-022-01270-1","volume":"55","author":"Chen","year":"2023","journal-title":"Nature Genet"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"3253","DOI":"10.1681\/asn.2016010098","volume":"27","author":"Sekula","year":"2016","journal-title":"J Am Soc Nephrol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/ije\/dyg070","volume":"32","author":"Smith","year":"2003","journal-title":"Int J Epidemiol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.34408","volume":"7","author":"Hemani","year":"2018","journal-title":"eLife"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1007\/s10654-017-0255-x","volume":"32","author":"Burgess","year":"2017","journal-title":"Eur J Epidemiol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1985","DOI":"10.1093\/ije\/dyx102","volume":"46","author":"Hartwig","year":"2017","journal-title":"Int J Epidemiol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"5434","DOI":"10.1002\/sim.9133","volume":"40","author":"Sanderson","year":"2021","journal-title":"Stat Med"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1038\/s41588-018-0099-7","volume":"50","author":"Verbanck","year":"2018","journal-title":"Nature Genet"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"1070","DOI":"10.1164\/rccm.201707-1339LE","volume":"197","author":"Scicluna","year":"2018","journal-title":"Am J Respir Crit Care Med"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1038\/s41467-023-44313-9","volume":"15","author":"Chen","year":"2024","journal-title":"Nat Commun"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"3573","DOI":"10.1016\/j.cell.2021.04.048","volume":"184","author":"Hao","year":"2021","journal-title":"Cell"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1038\/s41590-018-0276-y","volume":"20","author":"Aran","year":"2019","journal-title":"Nat Immunol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1038\/s41586-019-0969-x","volume":"566","author":"Cao","year":"2019","journal-title":"Nature"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1146\/annurev-publhealth-032315-021402","volume":"37","author":"VanderWeele","year":"2016","journal-title":"Ann Rev Public Health"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1093\/ije\/dyu176","volume":"44","author":"Burgess","year":"2015","journal-title":"Int J Epidemiol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"115224","DOI":"10.1016\/j.biopha.2023.115224","volume":"165","author":"Hu","year":"2023","journal-title":"Biomed Pharmacother"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1038\/s41420-023-01730-5","volume":"9","author":"Wang","year":"2023","journal-title":"Cell Death Discovery"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"eabi5751","DOI":"10.1126\/sciadv.abi5751","volume":"7","author":"Cheng","year":"2021","journal-title":"Sci Adv"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"3215","DOI":"10.1111\/febs.14604","volume":"285","author":"Nagashimada","year":"2018","journal-title":"FEBS J"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1093\/procel\/pwac012","volume":"14","author":"Arnold","year":"2023","journal-title":"Protein Cell"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.1007\/s40618-023-02292-0","volume":"47","author":"Yu","year":"2024","journal-title":"J Endocrinol Invest"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"526","DOI":"10.3389\/fimmu.2018.00526","volume":"9","author":"Arts","year":"2018","journal-title":"Front Immunol"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"e13205","DOI":"10.1111\/cpr.13205","volume":"55","author":"Du","year":"2022","journal-title":"Cell Proliferation"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"910626","DOI":"10.3389\/fcell.2022.910626","volume":"10","author":"Li","year":"2022","journal-title":"Front Cell Develop Biol"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"13448","DOI":"10.1038\/s41598-017-12573-3","volume":"7","author":"Feng","year":"2017","journal-title":"Sci Rep"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"351","DOI":"10.15252\/embj.201796781","volume":"37","author":"Du","year":"2018","journal-title":"EMBO J"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.bbrc.2018.09.065","volume":"506","author":"Zhang","year":"2018","journal-title":"Biochem Biophys Res Commun"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"824771","DOI":"10.3389\/fcell.2022.824771","volume":"10","author":"Han","year":"2022","journal-title":"Front Cell Develop Biol"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"1324","DOI":"10.1016\/j.joca.2021.06.010","volume":"29","author":"Zhang","year":"2021","journal-title":"Osteoarthritis Cartilage"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"e13006","DOI":"10.1111\/acel.13006","volume":"18","author":"Mohanty","year":"2019","journal-title":"Aging Cell"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"106692","DOI":"10.1016\/j.isci.2023.106692","volume":"26","author":"Wang","year":"2023","journal-title":"iScience"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"e12927","DOI":"10.1111\/acel.12927","volume":"18","author":"Patil","year":"2019","journal-title":"Aging Cell"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1038\/nrrheum.2013.160","volume":"10","author":"Risbud","year":"2014","journal-title":"Nat Rev Rheumatol"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"15874","DOI":"10.3390\/ijms242115874","volume":"24","author":"Iwasaki","year":"2023","journal-title":"Int J Mol Sci"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1007\/s00018-023-05094-y","volume":"81","author":"Zhang","year":"2024","journal-title":"Cell Mol Life Sci"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.3389\/fphar.2018.01043","volume":"9","author":"Liu","year":"2018","journal-title":"Front Pharmacol"}],"container-title":["Journal of Inflammation Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/99704","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/99704","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T10:40:30Z","timestamp":1738147230000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/clec11a-driven-molecular-mechanisms-in-intervertebral-disc-degeneratio-peer-reviewed-fulltext-article-JIR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":47,"URL":"https:\/\/doi.org\/10.2147\/jir.s505296","relation":{},"ISSN":["1178-7031"],"issn-type":[{"value":"1178-7031","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]}}}