{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T11:26:28Z","timestamp":1773833188727,"version":"3.50.1"},"reference-count":24,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JIR"],"DOI":"10.2147\/jir.s527482","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T12:35:12Z","timestamp":1754915712000},"page":"10885-10903","source":"Crossref","is-referenced-by-count":1,"title":["Unveiling the Therapeutic Potential of Jiawei Jianpi Huoyu Formula in Ulcerative Colitis: A Multi-Strategies and Experimental Study Integrating Network Pharmacology, Machine Learning, and Mendelian Randomization"],"prefix":"10.2147","volume":"Volume 18","author":[{"given":"Xiaobei","family":"Lu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yapeng","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9256-1213","authenticated-orcid":true,"given":"Man","family":"Gong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhigang","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueru","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1910-7591","authenticated-orcid":true,"given":"Liping","family":"Dai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erping","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1038\/s41572-020-0205-x","volume":"6","author":"Kobayashi","year":"2020","journal-title":"Nat Rev Dis Primers"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1016\/s0140-6736(23)00966-2","volume":"402","author":"Le Berre","year":"2023","journal-title":"Lancet"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"103017","DOI":"10.1016\/j.autrev.2021.103017","volume":"21","author":"Nakase","year":"2022","journal-title":"Autoimmunity Rev"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.3748\/wjg.v30.i9.1132","volume":"30","author":"Gravina","year":"2024","journal-title":"World J Gastroenterol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"e2400048","DOI":"10.1002\/adhm.202400048","volume":"13","author":"Liu","year":"2024","journal-title":"Adv Healthcare Mater"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"15026","DOI":"10.1021\/acsnano.2c06151","volume":"16","author":"Li","year":"2022","journal-title":"ACS Nano"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1016\/j.mayocp.2019.01.018","volume":"94","author":"Feuerstein","year":"2019","journal-title":"Mayo Clin Proc"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"e2101049","DOI":"10.1002\/mnfr.202101049","volume":"66","author":"Kim","year":"2022","journal-title":"Mol Nutr Food Res"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1781","DOI":"10.1142\/s0192415x22500756","volume":"50","author":"Zheng","year":"2022","journal-title":"Am J Chin Med"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"115084","DOI":"10.1016\/j.jep.2022.115084","volume":"289","author":"Liu","year":"2022","journal-title":"J Ethnopharmacol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"417","DOI":"10.5483\/BMBRep.2022.55.9.102","volume":"55","author":"Lee","year":"2022","journal-title":"BMB Rep"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"116306","DOI":"10.1016\/j.jep.2023.116306","volume":"309","author":"Zhao","year":"2023","journal-title":"J Ethnopharmacol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1525210","DOI":"10.3389\/fphar.2025.1525210","volume":"16","author":"Su","year":"2025","journal-title":"Front Pharmacol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"4913","DOI":"10.1093\/eurheartj\/ehad736","volume":"44","author":"Larsson","year":"2023","journal-title":"Eur Heart J"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1461","DOI":"10.1017\/s0033291724000321","volume":"54","author":"Chen","year":"2024","journal-title":"Psychol Med"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1080\/21691401.2025.2471762","volume":"53","author":"Huang","year":"2025","journal-title":"Artif Cells Nanomed Biotechnol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/ptr.8027","volume":"38","author":"Wang","year":"2024","journal-title":"Phytother Res"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"5771","DOI":"10.3390\/ijms20225771","volume":"20","author":"Dicarlo","year":"2019","journal-title":"Int J Mol Sci"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1007\/s00011-021-01468-9","volume":"70","author":"Li","year":"2021","journal-title":"Inflammation Res"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"119008","DOI":"10.1016\/j.lfs.2020.119008","volume":"269","author":"Li","year":"2021","journal-title":"Life Sci"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"679897","DOI":"10.3389\/fimmu.2021.679897","volume":"12","author":"Qu","year":"2021","journal-title":"Front Immunol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"210563","DOI":"10.1155\/2013\/210563","volume":"2013","author":"Uddin","year":"2013","journal-title":"Oxid Med Cell Longev"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"2057","DOI":"10.1007\/s10753-024-02025-2","volume":"47","author":"Zhao","year":"2024","journal-title":"Inflammation"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"1622","DOI":"10.12998\/wjcc.v12.i9.1622","volume":"12","author":"Gong","year":"2024","journal-title":"World J Clin Cases"}],"container-title":["Journal of Inflammation Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/105689","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/105689","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T12:35:12Z","timestamp":1754915712000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/unveiling-the-therapeutic-potential-of-jiawei-jianpi-huoyu-formula-in--peer-reviewed-fulltext-article-JIR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":24,"URL":"https:\/\/doi.org\/10.2147\/jir.s527482","relation":{},"ISSN":["1178-7031"],"issn-type":[{"value":"1178-7031","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8]]}}}