{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T11:58:34Z","timestamp":1786449514569,"version":"build-2736575974"},"reference-count":29,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JIR"],"DOI":"10.2147\/jir.s578682","type":"journal-article","created":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T02:05:21Z","timestamp":1767146721000},"page":"18323-18329","source":"Crossref","is-referenced-by-count":2,"title":["Dupilumab-Induced Systemic Hypoperfusion in an Elderly Patient: A Case Report"],"prefix":"10.2147","volume":"Volume 18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-6710-6319","authenticated-orcid":true,"given":"Huishang","family":"Feng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3071-295X","authenticated-orcid":true,"given":"Xinglu","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1038\/s41572-025-00605-6","volume":"11","author":"Akbarialiabad","year":"2025","journal-title":"Nat Rev Dis Primers"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"661","DOI":"10.2147\/CCID.S267573","volume":"15","author":"Ruggiero","year":"2022","journal-title":"Clin Cosmet Invest Dermatol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1590\/abd1806-4841.20199007","volume":"94","author":"Miyamoto","year":"2019","journal-title":"An Bras Dermatol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1038\/clpt.1981.154","volume":"30","author":"Naranjo","year":"1981","journal-title":"Clin Pharmacol Ther"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1159\/000469710","volume":"17","author":"Shen","year":"2017","journal-title":"Neurodegener Dis"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"adv00054","DOI":"10.2340\/00015555-3399","volume":"100","author":"Nishie","year":"2020","journal-title":"Acta Derm Venereol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1042\/EBC20180071","volume":"63","author":"Gatseva","year":"2019","journal-title":"Essays Biochem"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1161\/STROKEAHA.110.596361","volume":"42","author":"Yang","year":"2011","journal-title":"Stroke"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1111\/jdv.15444","volume":"33","author":"Papakonstantinou","year":"2019","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.abd.2022.01.012","volume":"98","author":"Wang","year":"2023","journal-title":"An Bras Dermatol"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"GBD. Stroke collaborators. global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the global burden of disease study 2019. Lancet Neurol. 2021;20(10):795\u2013820. doi:10.1016\/S1474-4422(21)00252-0.","DOI":"10.1016\/S1474-4422(21)00252-0"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1111\/jdv.20313","volume":"39","author":"Werth","year":"2025","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"738907","DOI":"10.3389\/fimmu.2021.738907","volume":"12","author":"Zhang","year":"2021","journal-title":"Front Immunol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.abd.2024.08.008","volume":"100","author":"da Silva","year":"2025","journal-title":"An Bras Dermatol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1194088","DOI":"10.3389\/fimmu.2023.1194088","volume":"14","author":"Yan","year":"2023","journal-title":"Front Immunol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1188","DOI":"10.1111\/all.14151","volume":"75","author":"A","year":"2020","journal-title":"Allergy"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1080\/21645515.2019.1582403","volume":"15","author":"Thibodeaux","year":"2019","journal-title":"Hum Vaccin Immunother"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1092685","DOI":"10.3389\/fimmu.2023.1092685","volume":"14","author":"Cao","year":"2023","journal-title":"Front Immunol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"546","DOI":"10.3390\/biom14050546","volume":"14","author":"Nakagome","year":"2024","journal-title":"Biomolecules"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"1638","DOI":"10.1016\/S0140-6736(19)31881-1","volume":"394","author":"Bachert","year":"2019","journal-title":"Lancet"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1038\/s41591-023-02320-9","volume":"29","author":"Yosipovitch","year":"2023","journal-title":"Nat Med"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1001\/jamadermatol.2023.2428","volume":"159","author":"Zhao","year":"2023","journal-title":"JAMA Dermatol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"2556294","DOI":"10.1080\/09546634.2025.2556294","volume":"36","author":"Fang","year":"2025","journal-title":"J DermatolTreat"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"115802","DOI":"10.1016\/j.jep.2022.115802","volume":"301","author":"Lin","year":"2023","journal-title":"J Ethnopharmacol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.3390\/ijms19041057","volume":"19","author":"Kong","year":"2018","journal-title":"Int J Mol Sci"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.1016\/j.immuni.2025.04.003","volume":"58","author":"Van Hove","year":"2025","journal-title":"Immunity"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.jaad.2020.08.051","volume":"84","author":"Halling","year":"2021","journal-title":"J Am Acad Dermatol"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"634","DOI":"10.3390\/biom13040634","volume":"13","author":"Olbrich","year":"2023","journal-title":"Biomolecules"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1080\/14740338.2024.2326480","volume":"23","author":"Camela","year":"2024","journal-title":"Expert Opin Drug Saf"}],"container-title":["Journal of Inflammation Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/110575","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/110575","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T02:05:25Z","timestamp":1767146725000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/dupilumab-induced-systemic-hypoperfusion-in-an-elderly-patient-a-case--peer-reviewed-fulltext-article-JIR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":29,"URL":"https:\/\/doi.org\/10.2147\/jir.s578682","relation":{},"ISSN":["1178-7031"],"issn-type":[{"value":"1178-7031","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12]]}}}