{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T13:10:10Z","timestamp":1751980210152,"version":"3.41.2"},"reference-count":61,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPR"],"DOI":"10.2147\/jpr.s521100","type":"journal-article","created":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T12:35:13Z","timestamp":1751978113000},"page":"3429-3438","source":"Crossref","is-referenced-by-count":0,"title":["A Bidirectional Mendelian Randomization Study of Causal Relationships Between Migraine and White-Matter Structural Connectivity"],"prefix":"10.2147","volume":"Volume 18","author":[{"given":"Dan","family":"Tong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyue","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiyong","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Supattra","family":"Taothong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prapawee","family":"Teeravarunyou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanxia","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sai","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuo","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siyuan","family":"Tao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8518-9268","authenticated-orcid":true,"given":"Fanrong","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1213-0382","authenticated-orcid":true,"given":"Zhengjie","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,7]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Headache Classification Committee of the International Headache Society (IHS). The international classification of headache disorders, 3rd edition. Cephalalgia. 2018;38(1):1\u2013211. doi:10.1177\/0333102417738202.","DOI":"10.1177\/0333102417738202"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1038\/s41582-022-00763-1","volume":"19","author":"Steiner","year":"2023","journal-title":"Nat Rev Neurol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1874","DOI":"10.1001\/jama.2021.1640","volume":"325","author":"Robbins","year":"2021","journal-title":"JAMA"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1038\/ng.3285","volume":"47","author":"Polderman","year":"2015","journal-title":"Nat Genet"},{"key":"ref5","first-page":"225","volume":"36","author":"Ulrich","year":"1999","journal-title":"J Med Genet"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/s10194-023-01547-8","volume":"24","author":"Grangeon","year":"2023","journal-title":"J Headache Pain"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1038\/s41588-021-00990-0","volume":"54","author":"Hautakangas","year":"2022","journal-title":"Nat Genet"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/s1474-4422(14)70193-0","volume":"14","author":"Schwedt","year":"2015","journal-title":"Lancet Neurol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1097\/wco.0000000000001060","volume":"35","author":"Messina","year":"2022","journal-title":"Curr Opin Neurol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1007\/s00415-022-11363-w","volume":"270","author":"Zhang","year":"2023","journal-title":"J Neurol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"103312","DOI":"10.1016\/j.nicl.2023.103312","volume":"37","author":"Zhang","year":"2023","journal-title":"Neuroimage Clin"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"3253","DOI":"10.1681\/asn.2016010098","volume":"27","author":"Sekula","year":"2016","journal-title":"J Am Soc Nephrol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1925","DOI":"10.1001\/jama.2017.17219","volume":"318","author":"Emdin","year":"2017","journal-title":"JAMA"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"k601","DOI":"10.1136\/bmj.k601","volume":"362","author":"Davies","year":"2018","journal-title":"BMJ"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"6484","DOI":"10.3390\/ijerph18126484","volume":"18","author":"Besser","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1038\/s41593-022-01174-7","volume":"25","author":"Guo","year":"2022","journal-title":"Nat Neurosci"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1177\/0333102420916751","volume":"40","author":"Daghlas","year":"2020","journal-title":"Cephalalgia"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"3214","DOI":"10.1093\/brain\/awac105","volume":"145","author":"Mitchell","journal-title":"Brain"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1148458","DOI":"10.3389\/fnins.2023.1148458","volume":"17","author":"Guo","year":"2023","journal-title":"Front Neurosci"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"23901","DOI":"10.1038\/s41598-024-74745-2","volume":"14","author":"Lu","year":"2024","journal-title":"Sci Rep"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/s10194-023-01550-z","volume":"24","author":"Zhao","year":"2023","journal-title":"J Headache Pain"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1016\/j.neuroimage.2006.12.021","volume":"35","author":"Kochunov","year":"2007","journal-title":"Neuroimage"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"10422","DOI":"10.1073\/pnas.96.18.10422","volume":"96","author":"Conturo","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"e3785","DOI":"10.1002\/nbm.3785","volume":"32","author":"Jeurissen","year":"2019","journal-title":"NMR Biomed"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"118870","DOI":"10.1016\/j.neuroimage.2021.118870","volume":"249","author":"Zhang","year":"2022","journal-title":"Neuroimage"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.neuroscience.2022.02.001","volume":"487","author":"Mao","year":"2022","journal-title":"Neuroscience"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1389","DOI":"10.1016\/j.jpain.2022.02.012","volume":"23","author":"Xu","year":"2022","journal-title":"J Pain"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1177\/0333102419885392","volume":"40","author":"Planchuelo-G\u00f3mez","year":"2020","journal-title":"Cephalalgia"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1186\/s10194-024-01806-2","volume":"25","author":"Noh","year":"2024","journal-title":"J Headache Pain"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"1962","DOI":"10.1038\/s41467-024-46023-2","volume":"15","author":"Wainberg","year":"2024","journal-title":"Nat Commun"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1152\/jn.00338.2011","volume":"106","author":"Yeo","year":"2011","journal-title":"J Neurophysiol"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1038\/ng.3406","volume":"47","author":"Bulik-Sullivan","year":"2015","journal-title":"Nat Genet"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1038\/ng.3211","volume":"47","author":"Bulik-Sullivan","year":"2015","journal-title":"Nat Genet"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1093\/ije\/dyr036","volume":"40","author":"Burgess","year":"2011","journal-title":"Int J Epidemiol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"3443","DOI":"10.1158\/0008-5472.Can-20-0985","volume":"80","author":"Lin","year":"2020","journal-title":"Cancer Res"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1016\/s1474-4422(22)00211-3","volume":"21","author":"Seng","year":"2022","journal-title":"Lancet Neurol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"4169","DOI":"10.1093\/cercor\/bhy300","volume":"29","author":"Zhao","year":"2019","journal-title":"Cereb Cortex"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1007\/s10654-015-0011-z","volume":"30","author":"Burgess","year":"2015","journal-title":"Eur J Epidemiol"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1002\/gepi.21758","volume":"37","author":"Burgess","year":"2013","journal-title":"Genet Epidemiol"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1002\/gepi.21965","volume":"40","author":"Bowden","year":"2016","journal-title":"Genet Epidemiol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"1985","DOI":"10.1093\/ije\/dyx102","volume":"46","author":"Hartwig","year":"2017","journal-title":"Int J Epidemiol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1093\/ije\/dyv080","volume":"44","author":"Bowden","year":"2015","journal-title":"Int J Epidemiol"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","volume":"57","author":"Benjamini","year":"2018","journal-title":"J Royal Stat Soc Series B"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/s00439-007-0448-6","volume":"123","author":"Ebrahim","year":"2008","journal-title":"Hum Genet"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1038\/s41588-018-0099-7","volume":"50","author":"Verbanck","year":"2018","journal-title":"Nat Genet"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"877956","DOI":"10.3389\/fpsyt.2022.877956","volume":"13","author":"Li","year":"2022","journal-title":"Front Psychiatry"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"e3002910","DOI":"10.1371\/journal.pbio.3002910","volume":"22","author":"Gim","year":"2024","journal-title":"PLoS Biol"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/2049-9256-1-9","volume":"1","author":"Veinante","year":"2013","journal-title":"J Mol Psychiatry"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1097\/j.pain.0000000000001714","volume":"161","author":"Gandhi","year":"2020","journal-title":"Pain"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1177\/0333102414531155","volume":"34","author":"Kim","year":"2014","journal-title":"Cephalalgia"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"2635","DOI":"10.1002\/hbm.23548","volume":"38","author":"Hougaard","year":"2017","journal-title":"Hum Brain Mapp"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1111\/ene.12636","volume":"22","author":"Hougaard","year":"2015","journal-title":"Eur J Neurol"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"13746","DOI":"10.1523\/jneurosci.3687-09.2009","volume":"29","author":"Rodriguez-Raecke","year":"2009","journal-title":"J Neurosci"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1212\/WNL.0b013e3181b8791a","volume":"73","author":"Obermann","year":"2009","journal-title":"Neurology"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"e0301543","DOI":"10.1371\/journal.pone.0301543","volume":"19","author":"Kosuge","year":"2024","journal-title":"PLoS One"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1097\/01.GOX.0000992272.93365.45","volume":"11","author":"R","year":"2023","journal-title":"Plast Reconstr Surg Glob Open"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1186\/s10194-024-01866-4","volume":"25","author":"Bharath","year":"2024","journal-title":"J Headache Pain"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1111\/head.13479","volume":"59","author":"Stilling","year":"2019","journal-title":"Headache"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"1565","DOI":"10.1111\/head.12981","volume":"56","author":"Shirahige","year":"2016","journal-title":"Headache"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"1669","DOI":"10.1007\/s10072-023-07195-9","volume":"45","author":"Tedeschi","year":"2024","journal-title":"Neurol Sci"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"31","DOI":"10.3822\/ijtmb.v17i3.971","volume":"17","author":"Tedeschi","year":"2024","journal-title":"Int J Ther Massage Bodywork"}],"container-title":["Journal of Pain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/104634","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/104634","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T12:35:16Z","timestamp":1751978116000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/a-bidirectional-mendelian-randomization-study-of-causal-relationships--peer-reviewed-fulltext-article-JPR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":61,"URL":"https:\/\/doi.org\/10.2147\/jpr.s521100","relation":{},"ISSN":["1178-7090"],"issn-type":[{"value":"1178-7090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7]]}}}