{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T03:36:13Z","timestamp":1769657773393,"version":"3.49.0"},"reference-count":61,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPR"],"DOI":"10.2147\/jpr.s564911","type":"journal-article","created":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T16:05:11Z","timestamp":1769616311000},"page":"1-17","source":"Crossref","is-referenced-by-count":0,"title":["Periplaneta americana Powder Alleviates Neuropathic Pain and is Associated with Gut Microbiota Changes in Rats"],"prefix":"10.2147","volume":"Volume 19","author":[{"given":"Dan","family":"Luo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuaiying","family":"Jia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenting","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhidong","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3892-5108","authenticated-orcid":true,"given":"Wenqin","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2026,1]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"17002","DOI":"10.1038\/nrdp.2017.2","volume":"3","author":"Colloca","year":"2017","journal-title":"Nat Rev Dis Primers"},{"key":"ref2","first-page":"104","volume":"34","author":"Hai-chun","year":"2015","journal-title":"Chin Foreign Med J"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1080\/13880209.2023.2198560","volume":"61","author":"Zhang","year":"2023","journal-title":"Pharm Biol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.bbi.2024.02.027","volume":"118","author":"Hua","year":"2024","journal-title":"Brain Behav Immun"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"106675","DOI":"10.1016\/j.biocel.2024.106675","volume":"176","author":"Luo","year":"2024","journal-title":"Int J Biochem Cell Biol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1186\/s12974-022-02489-9","volume":"19","author":"Li","year":"2022","journal-title":"J Neuroinflamm"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1097\/AAP.0000000000000780","volume":"43","author":"Zhao","year":"2018","journal-title":"Reg Anesth Pain Med"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.expneurol.2008.07.016","volume":"214","author":"Hulsebosch","year":"2008","journal-title":"Exp Neurol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/j.pain.2009.09.030","volume":"147","author":"Carlton","year":"2009","journal-title":"Pain"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1172\/JCI81950","volume":"126","author":"Jiang","year":"2016","journal-title":"J Clin Invest"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"2009","DOI":"10.3892\/ijmm.2018.3763","volume":"42","author":"Chen","year":"2018","journal-title":"Int J Mol Med"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1038\/nrd1852","volume":"4","author":"White","year":"2005","journal-title":"Nat Rev Drug Discov"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1016\/j.bja.2019.07.026","volume":"123","author":"Guo","year":"2019","journal-title":"Br J Anaesth"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1186\/s12974-022-02523-w","volume":"19","author":"Ma","year":"2022","journal-title":"J Neuroinflamm"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1342833","DOI":"10.3389\/fimmu.2024.1342833","volume":"15","author":"Goudman","year":"2024","journal-title":"Front Immunol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"155740","DOI":"10.1016\/j.phymed.2024.155740","volume":"132","author":"Di","year":"2024","journal-title":"Phytomedicine"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/j.jad.2024.02.069","volume":"360","author":"Li","year":"2024","journal-title":"J Affect Disord"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1007\/s00018-024-05332-x","volume":"81","author":"Lin","year":"2024","journal-title":"Cell Mol Life Sci"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"e01260","DOI":"10.1002\/brb3.1260","volume":"9","author":"Huang","year":"2019","journal-title":"Brain Behav"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"660","DOI":"10.7679\/j.issn.2095-1353.2024.069","volume":"61","author":"Huamei","year":"2024","journal-title":"J Appl Entomol"},{"key":"ref21","first-page":"19","volume":"35","author":"Yanbo","year":"2025","journal-title":"J Integrat Trad Western Med Zhejiang Province"},{"key":"ref22","first-page":"98","volume":"32","author":"Fu-de","year":"2020","journal-title":"China Commun Med"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.19338\/j.issn.1672-2019.2023.12.001","volume":"31","author":"Fucheng","year":"2023","journal-title":"Chin Med Eng"},{"key":"ref24","first-page":"1889","volume":"42","author":"Lei","year":"2020","journal-title":"Chin Trad Patent Med"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1007\/s11596-023-2723-8","volume":"43","author":"Nguyen","year":"2023","journal-title":"Curr Med Sci"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"944","DOI":"10.3389\/fphar.2018.00944","volume":"9","author":"Ma","year":"2018","journal-title":"Front Pharmacol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"117400","DOI":"10.1016\/j.jep.2023.117400","volume":"321","author":"Rao","year":"2024","journal-title":"J Ethnopharmacol"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"108","DOI":"10.13193\/j.issn.1673-7717.2021.08.024","volume":"39","author":"Wang","year":"2021","journal-title":"Chin Arch Trad Chin Med"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"58","DOI":"10.3969\/j.issn.1005-4847.2024.01.001","volume":"32","author":"Jie","year":"2024","journal-title":"Acta Laboratorium Animalis Scientia Sinica"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.vascn.2012.04.006","volume":"66","author":"Nirogi","year":"2012","journal-title":"J Pharmacol Toxicol Methods"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1038\/nmeth.1923","volume":"9","author":"Langmead","year":"2012","journal-title":"Nat Methods"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"27663","DOI":"10.3402\/mehd.v26.27663","volume":"26","author":"Mandal","year":"2015","journal-title":"Microb Ecol Health Dis"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1038\/s41592-018-0176-y","volume":"15","author":"Franzosa","year":"2018","journal-title":"Nat Methods"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"S10","DOI":"10.1016\/j.pain.2013.06.022","volume":"154","author":"Ji","year":"2013","journal-title":"Pain"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1186\/s12974-017-0947-x","volume":"14","author":"Jiang","year":"2017","journal-title":"J Neuroinflammation"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1007\/s12640-020-00245-6","volume":"38","author":"Zhao","year":"2020","journal-title":"Neurotox Res"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.1213\/ANE.0000000000005155","volume":"132","author":"Ding","year":"2021","journal-title":"Anesth Analg"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1186\/s13041-021-00765-y","volume":"14","author":"Chen","year":"2021","journal-title":"Mol Brain"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"115442","DOI":"10.1016\/j.bbr.2025.115442","volume":"482","author":"Zhao","year":"2025","journal-title":"Behav Brain Res"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"116769","DOI":"10.1016\/j.biopha.2024.116769","volume":"175","author":"Huang","year":"2024","journal-title":"Biomed Pharmacother"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.chom.2024.11.013","volume":"33","author":"Jiang","year":"2025","journal-title":"Cell Host Microbe"},{"key":"ref42","first-page":"110","volume":"14","author":"Chaqun","year":"2019","journal-title":"Chin J Pathogenic Biol"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"1228754","DOI":"10.3389\/fimmu.2023.1228754","volume":"14","author":"Luo","year":"2023","journal-title":"Front Immunol"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1002\/jsfa.13908","volume":"105","author":"Qin","year":"2025","journal-title":"J Sci Food Agric"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"110943","DOI":"10.1016\/j.brainresbull.2024.110943","volume":"211","author":"Wu","year":"2024","journal-title":"Brain Res Bull"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"12232","DOI":"10.3390\/ijms241512232","volume":"24","author":"O\u00f1ate","year":"2023","journal-title":"Int J Mol Sci"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"2069","DOI":"10.3390\/nu14102069","volume":"14","author":"Guo","year":"2022","journal-title":"Nutrients"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1186\/s13568-023-01614-y","volume":"13","author":"Jiao","year":"2023","journal-title":"AMB Express"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1574-6968.2009.01514.x","volume":"294","author":"Louis","year":"2009","journal-title":"FEMS Microbiol Lett"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"e00889","DOI":"10.1128\/mBio.00889-14","volume":"5","author":"Vital","year":"2014","journal-title":"mBio"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"2141","DOI":"10.1099\/00207713-52-6-2141","volume":"52","author":"Duncan","year":"2002","journal-title":"Int J Syst Evol Microbiol"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"1499","DOI":"10.3390\/nu10101499","volume":"10","author":"Bach Knudsen","year":"2018","journal-title":"Nutrients"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/19490976.2021.1875796","volume":"13","author":"Liu","year":"2021","journal-title":"Gut Microbes"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"1354","DOI":"10.2174\/1570159X19666210215123239","volume":"19","author":"Zhao","year":"2021","journal-title":"Curr Neuropharmacol"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1111\/cns.14077","volume":"29","author":"Li","year":"2023","journal-title":"CNS Neurosci Ther"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1136\/gutjnl-2013-304833","volume":"63","author":"Machiels","year":"2014","journal-title":"Gut"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"1696","DOI":"10.3390\/ijms17101696","volume":"17","author":"Miao","year":"2016","journal-title":"Int J Mol Sci"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"108849","DOI":"10.1016\/j.biopha.2019.108849","volume":"114","author":"Shen","year":"2019","journal-title":"Biomed Pharmacother"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"mgen000399","DOI":"10.1099\/mgen.0.000399","volume":"6","author":"Hillman","year":"2020","journal-title":"Microb Genom"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"e2300180","DOI":"10.1002\/biot.202300180","volume":"18","author":"Song","year":"2023","journal-title":"Biotechnol J"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"109753","DOI":"10.1016\/j.biopha.2019.109753","volume":"123","author":"Nguyen","year":"2020","journal-title":"Biomed Pharmacother"}],"container-title":["Journal of Pain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/111409","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/111409","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T16:05:16Z","timestamp":1769616316000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/periplaneta-americana-powder-alleviates-neuropathic-pain-and-is-associ-peer-reviewed-fulltext-article-JPR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":61,"URL":"https:\/\/doi.org\/10.2147\/jpr.s564911","relation":{},"ISSN":["1178-7090"],"issn-type":[{"value":"1178-7090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]}}}