{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T02:17:52Z","timestamp":1784686672018,"version":"3.55.0"},"reference-count":43,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPR"],"DOI":"10.2147\/jpr.s614007","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T07:00:18Z","timestamp":1781593218000},"page":"1-12","source":"Crossref","is-referenced-by-count":1,"title":["Diurnal Variation in Intraoperative Opioid Requirements: A Prospective Cohort Study"],"prefix":"10.2147","volume":"Volume 19","author":[{"given":"Zhe","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoying","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4826-8554","authenticated-orcid":true,"given":"Huamei","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianran","family":"Gang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaowen","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1441020","DOI":"10.3389\/fimmu.2024.1441020","volume":"15","author":"Guo","year":"2024","journal-title":"Front Immunol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1001\/jamasurg.2023.2009","volume":"158","author":"Santa Cruz Mercado","year":"2023","journal-title":"JAMA Surg"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"S11","DOI":"10.1097\/j.pain.0000000000000775","volume":"158 Suppl 1","author":"Fillingim","year":"2017","journal-title":"Pain"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"S108","DOI":"10.1097\/j.pain.0000000000002738","volume":"163","author":"Keogh","year":"2022","journal-title":"Pain"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"32","DOI":"10.2106\/jbjs.20.00237","volume":"102 Suppl 1","author":"Templeton","year":"2020","journal-title":"J Bone Joint Surg Am"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"4280","DOI":"10.1093\/brain\/awae179","volume":"147","author":"Stratton","year":"2024","journal-title":"Brain"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"afae107","DOI":"10.1093\/ageing\/afae107","volume":"53","author":"Zhi","year":"2024","journal-title":"Age Ageing"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1220","DOI":"10.1111\/anae.16391","volume":"79","author":"El-Boghdadly","year":"2024","journal-title":"Anaesthesia"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1007\/s44254-023-00043-1","volume":"2","author":"Kianian","year":"2024","journal-title":"Anesthesiology and Perioperative Science"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.jor.2021.02.028","volume":"24","author":"Lendrum","year":"2021","journal-title":"J Orthop"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1007\/s11916-020-0844-3","volume":"24","author":"Coppes","year":"2020","journal-title":"Curr Pain Headache Rep"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"2407","DOI":"10.2147\/jpr.S420447","volume":"16","author":"Elgendy","year":"2023","journal-title":"J Pain Res"},{"key":"ref13","unstructured":"Bienert A, Bartkowska-\u015bniatkowska A. Selected aspects of chronobiological studies in anaesthesia. 2014."},{"key":"ref14","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1038\/s41580-019-0179-2","volume":"21","author":"Patke","year":"2020","journal-title":"Nat Rev Mol Cell Biol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"16219","DOI":"10.1073\/pnas.1408886111","volume":"111","author":"Zhang","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"S20","DOI":"10.1111\/j.1526-4637.2009.00596.x","volume":"10","author":"Holmquist","year":"2009","journal-title":"Pain Medicine"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1016\/j.neubiorev.2021.08.004","volume":"129","author":"Bum Garner","year":"2021","journal-title":"Neurosci Biobehav Rev"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"993506","DOI":"10.3389\/fphar.2022.993506","volume":"13","author":"Gan","year":"2022","journal-title":"Front Pharmacol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"183","DOI":"10.2147\/jpr.S13616","volume":"3","author":"Boom","year":"2010","journal-title":"J Pain Res"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.1124\/dmd.104.000927","volume":"32","author":"Uhing","year":"2004","journal-title":"Drug Metab Dispos"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"285","DOI":"10.2165\/00003088-199121040-00005","volume":"21","author":"Wood","year":"1991","journal-title":"Clin Pharmacokinet"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1111\/aas.13533","volume":"64","author":"Hahn","year":"2020","journal-title":"Acta Anaesthesiol Scand"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"31","DOI":"10.4097\/kja.23158","volume":"77","author":"Oh","year":"2024","journal-title":"Korean J Anesthesiol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1097\/eja.0000000000001877","volume":"40","author":"Mestdagh","year":"2023","journal-title":"Eur J Anaesthesiol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1111\/j.1365-2044.1989.tb11086.x","volume":"44","author":"Burns","year":"1989","journal-title":"Anaesthesia"},{"key":"ref26","first-page":"49","volume":"2","author":"Graves","year":"1983","journal-title":"Clin Pharm"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.1016\/j.bja.2023.08.039","volume":"131","author":"Shu","year":"2023","journal-title":"Br J Anaesth"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"231","DOI":"10.2165\/00003088-199529040-00003","volume":"29","author":"Lemmens","year":"1995","journal-title":"Clin Pharmacokinet"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1007\/s00540-022-03094-z","volume":"36","author":"Hung","year":"2022","journal-title":"J Anesth"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1213\/ane.0000000000004388","volume":"130","author":"Funcke","year":"2020","journal-title":"Anesth Analg"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1153107","DOI":"10.3389\/fpain.2023.1153107","volume":"4","author":"Edwards","year":"2023","journal-title":"Front Pain Res (Lausanne)"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1186\/s12964-023-01258-2","volume":"21","author":"Li","year":"2023","journal-title":"Cell Commun Signal"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"2743","DOI":"10.1097\/ms9.0000000000004865","volume":"88","author":"Xu","year":"2026","journal-title":"Ann Med Surg (Lond)"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"1010","DOI":"10.1111\/exd.13994","volume":"28","author":"Goto","year":"2019","journal-title":"Exp Dermatol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.1111\/j.1365-2044.2012.07267.x","volume":"67","author":"Choi","year":"2012","journal-title":"Anaesthesia"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"1178","DOI":"10.3390\/cells12081178","volume":"12","author":"Jovanovic","year":"2023","journal-title":"Cells"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"127","DOI":"10.3389\/fnbeh.2018.00127","volume":"12","author":"Godoy","year":"2018","journal-title":"Front Behav Neurosci"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1007\/s10928-021-09751-2","volume":"48","author":"Ayyar","year":"2021","journal-title":"J Pharmacokinet Pharmacodyn"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"114045","DOI":"10.1016\/j.bcp.2020.114045","volume":"178","author":"Dong","year":"2020","journal-title":"Biochem Pharmacol"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1080\/17425255.2024.2356167","volume":"20","author":"Okyar","year":"2024","journal-title":"Expert Opin Drug Metab Toxicol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s13041-023-00997-0","volume":"16","author":"Schurhoff","year":"2023","journal-title":"Mol Brain"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"1109480","DOI":"10.3389\/fnins.2023.1109480","volume":"17","author":"Bumgarner","year":"2023","journal-title":"Front Neurosci"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1016\/j.bja.2023.11.027","volume":"132","author":"Liu","year":"2024","journal-title":"Br J Anaesth"}],"container-title":["Journal of Pain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/116425","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/116425","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T07:00:22Z","timestamp":1781593222000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/diurnal-variation-in-intraoperative-opioid-requirements-a-prospective--peer-reviewed-fulltext-article-JPR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":43,"URL":"https:\/\/doi.org\/10.2147\/jpr.s614007","relation":{},"ISSN":["1178-7090"],"issn-type":[{"value":"1178-7090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6]]}}}